Open nowCloses in 3 days (Nov 15, 2026)
Health Grants
NutritionDiabetes treatmentAlternative medicine
Who can apply: Must be a 501(c)(3) public charity and provide programs aligned with the Foundation's mission in health.
Health Grants in South Dakota
102 foundations fund health programs in South Dakota. See who they are, what they give, and how to reach them.
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These foundations have a track record of funding health work in South Dakota, based on IRS 990 grant data. Use the list below to find funders aligned with your mission, then sign up free to see how well your nonprofit fits each one.
Open Grant Opportunities
Live programs funding health in South Dakota that your nonprofit can apply to now.
Open nowCloses in 4 days (Nov 16, 2026)Award: Varies
Current Research Grants
From Children's Cancer Research Fund
childhood cancer researchhard-to-treat diseasessurvivorship+4 more
Who can apply: Research projects at institutions nationwide that are innovative and promising, with potential to prove an idea and help researchers secure larger grants; the funder emphasizes projects with fresh, ambitious ideas and impact for children with cancer.
Open nowCloses in 6 days (Nov 18, 2026)May not accept unsolicited proposalsAward: Varies
Demonstrating Health Solutions Science in Action
Health solutions scienceBehavioral health driversClinical health drivers+5 more
Who can apply: Lead applicant organizations should generally be U.S. 501(c)(3) public charities that are not private foundations or Type III supporting organizations. State universities are eligible. For-profit entities may not apply directly or indirectly through nonprofit venture philanthropy programs, though they may participate as collaborators. Proposals must be collaborative, cross-sectoral and multidisciplinary; focus on applying existing evidence to produce measurable health outcomes or validated proxies in the United States; include knowledge-user participation, stakeholder leverage, and a feasible three-year implementation and evaluation plan.
Open nowCloses in 6 days (Nov 18, 2026)May not accept unsolicited proposalsAward: Varies
Demonstrating Health Solutions Science in Action
From Doris Duke Management Foundation
Health solutions scienceHealth outcomesHealth systems+5 more
Who can apply: Teams must designate a lead applicant organization. Lead organizations may be knowledge users or producers and are encouraged to have 501(c)(3) status; state universities are eligible. Non-501(c)(3) entities may participate as collaborators. For-profit entities are not eligible to apply directly or indirectly through nonprofit venture philanthropy programs. Projects must focus on real-world application of evidence-based health solutions science in the United States, demonstrate measurable health impact, include relevant partnerships and leverage, and have a feasible three-year plan.
Open nowCloses in 6 days (Nov 18, 2026)May not accept unsolicited proposals
Demonstrating Health Solutions Science in Action
From Doris Duke Charitable Foundation
Health solutions scienceHealth researchPrevention+2 more
Who can apply: Detailed eligibility criteria were not included in the scraped content.
Open nowCloses in 8 days (Nov 20, 2026)Award: Up to $200K
Transformation of Mental Health Care Program
From Esther A & Joseph Klingenstein Fund
Child and adolescent mental healthMental health services researchImplementation science+5 more
Who can apply: Academic researchers at universities, research institutions, health systems, or other settings positioned to provide rigorous research may apply. Investigators must reside within institutions based in the United States, and all project research must be completed in the United States. Applicants may be at any career stage but must have sufficient pilot data and be established enough to lead the project; early-career investigators are strongly encouraged to collaborate with senior researchers. Co-applicants or principal investigators must be at the same institution. Proposals must include rigorous research, pilot data, implementation or service outcomes, and potential for future scale. Applicants may not apply for both a KTGF Fellowship grant and a Transformation of Mental Health Care grant in the same year.
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Find My Grant MatchesDeadlines and program details come from public sources and can change. Always confirm on the funder's official site before applying.
Largest Health in South Dakota Foundations
| Foundation | Location | Annual Giving | Total Assets | Median Grant | NTEE | Scope |
|---|---|---|---|---|---|---|
| MAYO CLINIC GROUP RETURN | ROCHESTER, MN | $1.7B | $17.9B | $18K | E21 | National |
| MAYO CLINIC | ROCHESTER, MN | $572.1M | $26.7B | $52K | E21 | National |
| American Heart Association Inc | Dallas, TX | $198.2M | $2B | $26K | G430 | National |
| CYSTIC FIBROSIS FOUNDATION | BETHESDA, MD | $189.6M | $5B | $161K | G200 | National |
| Vanderbilt University Medical Center | Nashville, TN | $125.1M | $7.8B | $75K | E20 | National |
| FRED HUTCHINSON CANCER RESEARCH CENTER | SEATTLE, WA | $122.1M | — | $58K | H300 | National |
| FRED HUTCHINSON CANCER CENTER | SEATTLE, WA | $88.2M | $3.6B | $48K | E240 | National |
| Ronald McDonald House Charities Inc | Chicago, IL | $85.5M | $328.9M | $229K | E860 | National |
| BREAKTHROUGH T1D | NEW YORK, NY | $79.3M | $534.6M | $300K | G800 | National |
| ALZHEIMER'S DISEASE & RELATED DISORDERS ASSOCIATION INC | CHICAGO, IL | $73.3M | $523.7M | $250K | G830 | National |
| Public Health Institute | Oakland, CA | $58.8M | $133.3M | $50K | E70Z | Regional |
| SEATTLE CHILDREN'S HOSPITAL | SEATTLE, WA | $56.3M | $6B | $53K | E240 | National |
| SANFORD GROUP RETURN | SIOUX FALLS, SD | $45.3M | $4.3B | $20K | E21 | Regional |
| CARING FOR DENVER FOUNDATION | DENVER, CO | $43.6M | $114.8M | $170K | F20 | Local |
| Southern Baptist Hospital of Florida Inc | Jacksonville, FL | $38.8M | $5.2B | $43K | E220 | Local |
| JSI RESEARCH & TRAINING INSTITUTE INC | BOSTON, MA | $37.4M | $195.8M | $43K | E70 | National |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA | SEATTLE, WA | $27.5M | $95.5M | $116K | H920 | National |
| HEALTH RESOURCES IN ACTION INC | BOSTON, MA | $26.2M | $122.5M | $75K | H99 | Local |
| AMERICAN CANCER SOCIETY INC | Atlanta, GA | $23.1M | $1.7B | $20K | G300 | National |
| LIFESCAPE FOUNDATION | SIOUX FALLS, SD | $18.4M | $155.2M | $1.3M | E50J | Local |
| American Dental Association | Chicago, IL | $18.2M | $286.9M | $57K | E99 | National |
| BROADWAY CARESEQUITY FIGHTS AIDS INC | NEW YORK, NY | $17.1M | $16.8M | $13K | G81 | National |
| BOB WOODRUFF FAMILY FOUNDATION INC | LONG ISLAND CITY, NY | $16.8M | $73.3M | $50K | E99 | National |
| NORTHWEST PORTLAND AREA INDIAN HEALTH BOARD | PORTLAND, OR | $13.3M | $290.8M | $101K | E70Z | Regional |
| ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY FOUNDATION | CHICAGO, IL | $12.8M | $112.8M | $25K | H31Z | National |
MAYO CLINIC GROUP RETURN
ROCHESTER, MN
Annual Giving
$1.7B
Total Assets
$17.9B
Median Grant
$18K
E21National
American Heart Association Inc
Dallas, TX
Annual Giving
$198.2M
Total Assets
$2B
Median Grant
$26K
G430National
CYSTIC FIBROSIS FOUNDATION
BETHESDA, MD
Annual Giving
$189.6M
Total Assets
$5B
Median Grant
$161K
G200National
Vanderbilt University Medical Center
Nashville, TN
Annual Giving
$125.1M
Total Assets
$7.8B
Median Grant
$75K
E20National
FRED HUTCHINSON CANCER RESEARCH CENTER
SEATTLE, WA
Annual Giving
$122.1M
Total Assets
—
Median Grant
$58K
H300National
FRED HUTCHINSON CANCER CENTER
SEATTLE, WA
Annual Giving
$88.2M
Total Assets
$3.6B
Median Grant
$48K
E240National
Ronald McDonald House Charities Inc
Chicago, IL
Annual Giving
$85.5M
Total Assets
$328.9M
Median Grant
$229K
E860National
ALZHEIMER'S DISEASE & RELATED DISORDERS ASSOCIATION INC
CHICAGO, IL
Annual Giving
$73.3M
Total Assets
$523.7M
Median Grant
$250K
G830National
Public Health Institute
Oakland, CA
Annual Giving
$58.8M
Total Assets
$133.3M
Median Grant
$50K
E70ZRegional
SEATTLE CHILDREN'S HOSPITAL
SEATTLE, WA
Annual Giving
$56.3M
Total Assets
$6B
Median Grant
$53K
E240National
CARING FOR DENVER FOUNDATION
DENVER, CO
Annual Giving
$43.6M
Total Assets
$114.8M
Median Grant
$170K
F20Local
Southern Baptist Hospital of Florida Inc
Jacksonville, FL
Annual Giving
$38.8M
Total Assets
$5.2B
Median Grant
$43K
E220Local
JSI RESEARCH & TRAINING INSTITUTE INC
BOSTON, MA
Annual Giving
$37.4M
Total Assets
$195.8M
Median Grant
$43K
E70National
BENAROYA RESEARCH INSTITUTE AT VIRGINIA
SEATTLE, WA
Annual Giving
$27.5M
Total Assets
$95.5M
Median Grant
$116K
H920National
HEALTH RESOURCES IN ACTION INC
BOSTON, MA
Annual Giving
$26.2M
Total Assets
$122.5M
Median Grant
$75K
H99Local
AMERICAN CANCER SOCIETY INC
Atlanta, GA
Annual Giving
$23.1M
Total Assets
$1.7B
Median Grant
$20K
G300National
American Dental Association
Chicago, IL
Annual Giving
$18.2M
Total Assets
$286.9M
Median Grant
$57K
E99National
BROADWAY CARESEQUITY FIGHTS AIDS INC
NEW YORK, NY
Annual Giving
$17.1M
Total Assets
$16.8M
Median Grant
$13K
G81National
BOB WOODRUFF FAMILY FOUNDATION INC
LONG ISLAND CITY, NY
Annual Giving
$16.8M
Total Assets
$73.3M
Median Grant
$50K
E99National
NORTHWEST PORTLAND AREA INDIAN HEALTH BOARD
PORTLAND, OR
Annual Giving
$13.3M
Total Assets
$290.8M
Median Grant
$101K
E70ZRegional
ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY FOUNDATION
CHICAGO, IL
Annual Giving
$12.8M
Total Assets
$112.8M
Median Grant
$25K
H31ZNational
Health grants by state
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