Open nowCloses in 3 days (Sep 30, 2026)
Hartford Area Community Foundation Grants
From Sioux Falls Area Community Foundation
YouthOlder adultsEducation+4 more
Who can apply: Projects must directly benefit the people of Hartford, South Dakota.
Health Grants in South Dakota
94 foundations fund health programs in South Dakota. See who they are, what they give, and how to reach them.
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These foundations have a track record of funding health work in South Dakota, based on IRS 990 grant data. Use the list below to find funders aligned with your mission, then sign up free to see how well your nonprofit fits each one.
Open Grant Opportunities
Live programs funding health in South Dakota that your nonprofit can apply to now.
Open nowCloses in 4 days (Oct 1, 2026)Award: $10K – $50K
Arts Grants
Arts
Who can apply: Priority is given to requests that create pathways to opportunities, such as art education or employment, especially for people with limited access to artistic experiences; preference for projects serving under-resourced communities and/or people with disabilities and for requests that address multiple focus areas.
Open nowCloses in 5 days (Oct 2, 2026)Award: Up to $500K
Journalism Grants
From National Institute for Health Care Mgmt Research & Educational Foundation
Health Care Costs & QualityHealth Care ConsolidationArtificial Intelligence+3 more
Who can apply: Journalists from national and local print, digital, trade, and broadcast news organizations, including nonprofit and for-profit news organizations, as well as freelancers, are welcome to apply.
Open nowCloses in 18 days (Oct 15, 2026)Award: Up to $5K
Animal Welfare and Appreciation Fund (Effie C. Skaarud & Wanda Covington Endowment)
From Sioux Falls Area Community Foundation
Animal welfareAnimal health and safetyPrevention of cruelty+2 more
Who can apply: Supports new or existing programs, full activity costs or portions thereof, serving the greater Sioux Falls area. Eligible work includes animal welfare, health and safety, prevention of cruelty, habitat and living conditions, and use of animals as companions or protectors.
Open nowCloses Oct 30, 2026Award: Up to $110K
Well-Being in FTD Pilot Grant
From Association for Frontotemporal Degeneration
Frontotemporal degenerationCaregiver well-beingNonpharmacologic interventions+5 more
Who can apply: PI must have a faculty appointment or equivalent position at a nonprofit or academic research institution. U.S. and international researchers are eligible. Investigators at all career stages may apply, although early-career investigators and new research directions are especially encouraged. Postdoctoral fellows may not serve as PIs unless they can verify a faculty-level appointment beginning by the funding period. Established investigators with substantial funding on the proposed topic are unlikely to be competitive.
Open nowCloses Nov 1, 2026Award: Varies
Centre County Community Action Grants
From State College Association of University Women
Equity for women and girlsEducationEconomic security+2 more
Who can apply: Applicants must be nonprofit organizations located in Centre County, Pennsylvania. Funded programs must relate to AAUW's mission of advancing equity for women and girls, and more than half of the program's clients must be women or girls. Grants support specific programs, not general organizational funding. Recipients must publicly acknowledge AAUW State College support and submit a program update six months after receiving funds and when applying again.
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Find My Grant MatchesDeadlines and program details come from public sources and can change. Always confirm on the funder's official site before applying.
Largest Health in South Dakota Foundations
| Foundation | Location | Annual Giving | Total Assets | Median Grant | NTEE | Scope |
|---|---|---|---|---|---|---|
| MAYO CLINIC GROUP RETURN | ROCHESTER, MN | $1.7B | $17.9B | $18K | E21 | National |
| MAYO CLINIC | ROCHESTER, MN | $572.1M | $26.7B | $52K | E21 | National |
| American Heart Association Inc | Dallas, TX | $198.2M | $2B | $26K | G430 | National |
| CYSTIC FIBROSIS FOUNDATION | BETHESDA, MD | $189.6M | $5B | $161K | G200 | National |
| Vanderbilt University Medical Center | Nashville, TN | $125.1M | $7.8B | $75K | E20 | National |
| FRED HUTCHINSON CANCER RESEARCH CENTER | SEATTLE, WA | $122.1M | — | $58K | H300 | National |
| FRED HUTCHINSON CANCER CENTER | SEATTLE, WA | $88.2M | $3.6B | $48K | E240 | National |
| Ronald McDonald House Charities Inc | Chicago, IL | $85.5M | $328.9M | $229K | E860 | National |
| BREAKTHROUGH T1D | NEW YORK, NY | $79.3M | $534.6M | $300K | G800 | National |
| ALZHEIMER'S DISEASE & RELATED DISORDERS ASSOCIATION INC | CHICAGO, IL | $73.3M | $523.7M | $250K | G830 | National |
| Public Health Institute | Oakland, CA | $58.8M | $133.3M | $50K | E70Z | Regional |
| SANFORD GROUP RETURN | SIOUX FALLS, SD | $45.3M | $4.3B | $20K | E21 | Regional |
| CARING FOR DENVER FOUNDATION | DENVER, CO | $43.6M | $114.8M | $170K | F20 | Local |
| SEATTLE CHILDREN'S HOSPITAL | SEATTLE, WA | $43M | $5.6B | $53K | E240 | National |
| Southern Baptist Hospital of Florida Inc | Jacksonville, FL | $35.8M | $4.7B | $43K | E220 | Local |
| BENAROYA RESEARCH INSTITUTE AT VIRGINIA | SEATTLE, WA | $27.5M | $95.5M | $116K | H920 | National |
| HEALTH RESOURCES IN ACTION INC | BOSTON, MA | $26.2M | $122.5M | $75K | H99 | Local |
| AMERICAN CANCER SOCIETY INC | Atlanta, GA | $23.1M | $1.7B | $20K | G300 | National |
| LIFESCAPE FOUNDATION | SIOUX FALLS, SD | $18.4M | $155.2M | $1.3M | E50J | Local |
| American Dental Association | Chicago, IL | $18.2M | $286.9M | $57K | E99 | National |
| BOB WOODRUFF FAMILY FOUNDATION INC | LONG ISLAND CITY, NY | $16.8M | $73.3M | $50K | E99 | National |
| BROADWAY CARESEQUITY FIGHTS AIDS INC | NEW YORK, NY | $14.6M | $15.9M | $13K | G81 | National |
| ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY FOUNDATION | CHICAGO, IL | $12.8M | $112.8M | $25K | H31Z | National |
| MUSCULAR DYSTROPHY ASSOCIATION INC | CHICAGO, IL | $12.6M | $50.9M | $35K | G50 | National |
| COMMUNITY CATALYST INC | BOSTON, MA | $12.1M | $48.4M | $73K | E99 | National |
MAYO CLINIC GROUP RETURN
ROCHESTER, MN
Annual Giving
$1.7B
Total Assets
$17.9B
Median Grant
$18K
E21National
American Heart Association Inc
Dallas, TX
Annual Giving
$198.2M
Total Assets
$2B
Median Grant
$26K
G430National
CYSTIC FIBROSIS FOUNDATION
BETHESDA, MD
Annual Giving
$189.6M
Total Assets
$5B
Median Grant
$161K
G200National
Vanderbilt University Medical Center
Nashville, TN
Annual Giving
$125.1M
Total Assets
$7.8B
Median Grant
$75K
E20National
FRED HUTCHINSON CANCER RESEARCH CENTER
SEATTLE, WA
Annual Giving
$122.1M
Total Assets
—
Median Grant
$58K
H300National
FRED HUTCHINSON CANCER CENTER
SEATTLE, WA
Annual Giving
$88.2M
Total Assets
$3.6B
Median Grant
$48K
E240National
Ronald McDonald House Charities Inc
Chicago, IL
Annual Giving
$85.5M
Total Assets
$328.9M
Median Grant
$229K
E860National
ALZHEIMER'S DISEASE & RELATED DISORDERS ASSOCIATION INC
CHICAGO, IL
Annual Giving
$73.3M
Total Assets
$523.7M
Median Grant
$250K
G830National
Public Health Institute
Oakland, CA
Annual Giving
$58.8M
Total Assets
$133.3M
Median Grant
$50K
E70ZRegional
CARING FOR DENVER FOUNDATION
DENVER, CO
Annual Giving
$43.6M
Total Assets
$114.8M
Median Grant
$170K
F20Local
SEATTLE CHILDREN'S HOSPITAL
SEATTLE, WA
Annual Giving
$43M
Total Assets
$5.6B
Median Grant
$53K
E240National
Southern Baptist Hospital of Florida Inc
Jacksonville, FL
Annual Giving
$35.8M
Total Assets
$4.7B
Median Grant
$43K
E220Local
BENAROYA RESEARCH INSTITUTE AT VIRGINIA
SEATTLE, WA
Annual Giving
$27.5M
Total Assets
$95.5M
Median Grant
$116K
H920National
HEALTH RESOURCES IN ACTION INC
BOSTON, MA
Annual Giving
$26.2M
Total Assets
$122.5M
Median Grant
$75K
H99Local
AMERICAN CANCER SOCIETY INC
Atlanta, GA
Annual Giving
$23.1M
Total Assets
$1.7B
Median Grant
$20K
G300National
American Dental Association
Chicago, IL
Annual Giving
$18.2M
Total Assets
$286.9M
Median Grant
$57K
E99National
BOB WOODRUFF FAMILY FOUNDATION INC
LONG ISLAND CITY, NY
Annual Giving
$16.8M
Total Assets
$73.3M
Median Grant
$50K
E99National
BROADWAY CARESEQUITY FIGHTS AIDS INC
NEW YORK, NY
Annual Giving
$14.6M
Total Assets
$15.9M
Median Grant
$13K
G81National
ALLIANCE FOR CLINICAL TRIALS IN ONCOLOGY FOUNDATION
CHICAGO, IL
Annual Giving
$12.8M
Total Assets
$112.8M
Median Grant
$25K
H31ZNational
MUSCULAR DYSTROPHY ASSOCIATION INC
CHICAGO, IL
Annual Giving
$12.6M
Total Assets
$50.9M
Median Grant
$35K
G50National
Health grants by state
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