About Mayo Clinic Group Return
Solving the world's toughest medical problems and providing the best possible patient-centered care through integrated clinical practice, research, and education.
Focus Areas
healthcare deliverymedical researchmedical educationclinical trialsglobal health
Funding Style
general operating supportproject/program supportresearch grant fundingunrestricted/charitable-purpose support
Topics
charitable program support (broad, sector-agnostic)research program supportexempt-purpose funding
About Mayo Clinic Group Return
Mayo Clinic Group Return’s largest recent grants all stay inside the Mayo Clinic system: $2.23 billion in 2024, $1.63 billion in 2025, and $1.31 billion in 2023 went to Mayo Clinic in Rochester for support of charitable programs. That pattern makes the funder’s core role clear: it channels very large resources into Mayo’s clinical, research, and education mission rather than distributing across a wide array of unrelated organizations. The grant list also shows material support beyond the main campus. Mayo Clinic Jacksonville received $160 million in 2023, while Mayo Foundation for Medical Education and Research received $1.46 million in 2024 for research program support. Outside the Mayo system, the foundation has made six- and seven-figure awards to universities, hospitals, and community organizations, including Washington University, Columbia University, Emory University, and St. Jude Children’s Research Hospital. The mix suggests a funder that combines internal institutional support with targeted external grants tied to research, charitable programs, and charitable purposes. Across the recent grants file, support is overwhelmingly domestic and heavily centered on healthcare, medical research, medical education, clinical trials, and global health.
What Mayo Clinic Group Return Funds
Healthcare delivery appears in both system-level and community-facing grants. Mayo Clinic Jacksonville received $160 million in 2023, and Circle the City received $1 million in 2024 for support of charitable programs. These awards point to a funder that backs direct care infrastructure as well as charitable health services. Medical research is another visible thread. Indiana University received $2.97 million in 2025 for support of research program, and the University of California Irvine received $1.06 million in 2025 for the same purpose. University-based research also appears at the University of Florida, where a 2025 grant of $946,634 supported a research program. The foundation also funds education-linked and research-adjacent institutions. Independent School District 535 received $10 million in 2024, while Mayo Foundation for Medical Education and Research received $1.46 million in 2024 for research program support. These grants align with a broader emphasis on medical education and clinical training.
How Mayo Clinic Group Return Gives
Typical grants are relatively small next to the largest awards, with a p25 of $10,000, a median of $18,050, and a p75 of $59,500. The recent list also shows a small number of very large institutional grants, especially within the Mayo system, alongside many mid-sized awards to universities and nonprofits. The pattern is strongly recurring: Mayo Clinic appears in 2023, 2024, and 2025, and several recipients, including Washington University, Columbia University, Emory University, Nexus Family Healing, and St. Jude Children’s Research Hospital, appear more than once. The foundation is a regular funder and does not fund individuals or make program-related investments.
Financial Snapshot
Annual Giving
$1.7B
Total Assets
$17.9B
Total Revenue
$14.9B
Total Expenses
$14.3B
Typical Grant Size
Most grants fall between $10K and $60K, with a median of $18K.
25th Percentile
$10K
Median
$18K
75th Percentile
$60K
Geographic Reach
National39 states funded
About 16% of grants go to recipients in MN.
Funding intensity
LowHigh
Headquarters
Leadership
GIANRICO FARRUGIA MD
Unlock Deep Analysis
Sign up for a free Kindora account to access AI-generated insights into this funder's giving patterns, decision-makers, and fit signals.
Get Started FreeSee Similar Funders
Free Kindora accounts unlock side-by-side comparisons with foundations that share this funder's focus areas and giving profile.
Get Started FreeExplore related grant guides
Want a Personalized Pitch for Mayo Clinic Group Return?
Sign up free to see how well your nonprofit fits this funder, get an AI-generated pitch, and unlock similar foundations.
Free plan available
No contracts
Cancel anytime