Uniting for a world immune to cancer by turning immunotherapy research into real-world impact and changing the way we treat and defeat cancer.
Cancer Research Institute Inc backed a $9,002,197 grant to Johns Hopkins University School of Medicine in 2024, a signal of how much of its capital is directed toward research that can move immunotherapy into clinical use. The foundation’s giving is built around cancer immunotherapy, with support for multi-center clinical trials, translational research, data infrastructure, and career development for researchers. Its program mix reaches from early-stage ideas to late-stage clinical studies, including the CRI Anna-Maria Kellen Clinical Accelerator / Venture Philanthropy Fund and the CRI Lloyd J. Old STAR Program. It also funds investigator training through postdoctoral fellowships and transition awards, helping scientists build careers in immunology, bioinformatics, and cancer research. Recent grants show repeated support for major academic medical centers and research institutes, including University of California San Francisco, Dana-Farber Cancer Institute Inc, Memorial Sloan Kettering Cancer Center, and Columbia University in the City of New York. The pattern is one of sustained research funding rather than a single project category, with awards reaching across laboratory discovery, clinical translation, and shared data resources.
Cancer immunotherapy is the central thread across the foundation’s program portfolio. In clinical translation, it gave $1,000,000 to academic researchers through the CRI Clinical Innovator program for pioneering immunotherapy clinical trials, and $1,250,000 through the CRI Lloyd J. Old STAR Program for high-risk research at the leading edge of the field. It also supports the laboratory-to-clinic pipeline through the CRI Clinic and Laboratory Integration Program (CLIP), which funds investigations at the intersection of discovery and clinical application. On the data side, CRI Data Programs back AI-ready resources and shared tools, including the CRI Discovery Engine. Career-building is another recurring theme: the CRI Immuno-Informatics Postdoctoral Fellowship and the CRI Irvington Postdoctoral Fellowship support early-career scientists developing expertise in immunology, bioinformatics, and cancer immunology.
Typical award size clusters in the six-figure range, with p25 at $175,500, a median of $243,000, and p75 at $543,000. The recent grants list also shows several larger awards above $1 million, including multi-year support to research institutions and clinical programs. The foundation appears to combine recurring programmatic awards with one-off project grants, and some recipients appear in multiple years, such as University of California San Francisco, Columbia University in the City of New York, Yale University School of Medicine, and Memorial Sloan Kettering Cancer Center. It is a regular funder rather than a DAF, and it does not fund individuals. Several active programs accept unsolicited applications, including fellowships and research awards, while some data and accelerator programs do not.
$15.8M
$133.7M
$24M
$32.8M
Most grants fall between $176K and $543K, with a median of $243K.
25th Percentile
$176K
Median
$243K
75th Percentile
$543K
About 19% of grants go to recipients in NY.
ALICIA ZHOU PHD
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Grantmaking is national, and every grant in the recipient distribution is in the United States. New York is the top state by grant count, with 19% of grants going to recipients in NY, including New York City institutions such as Memorial Sloan Kettering Cancer Center, The Rockefeller University, and New York University Medical Center. Other recurring recipient cities include San Francisco, Boston, Philadelphia, New Haven, and Stanford. The list also reaches Baltimore, Seattle, Tampa, Atlanta, Houston, and Cambridge.
Its active programs center on cancer immunotherapy, with support for clinical trials, translational research, immunology, bioinformatics, and shared data infrastructure. The portfolio includes the Clinical Accelerator / Venture Philanthropy Fund, postdoctoral fellowships, technology awards, and clinical innovation grants.
Yes, several active programs do. The CRI Immuno-Informatics Postdoctoral Fellowship, CRI Irvington Postdoctoral Fellowship, CRI Technology Impact Award, CRI Lloyd J. Old STAR Program, CRI Clinical Innovator, CLIP, and CRI IGNITE Award all accept unsolicited applications.
Typical awards cluster around $243,000, with p25 at $175,500 and p75 at $543,000. The recent grants list also includes awards at $1,000,000, $1,250,000, and $9,002,197, showing that the foundation funds both mid-sized project grants and much larger institutional awards.
The giving is national, and 100% of the recipient distribution is in the United States. New York receives the largest share of grants by count at 19%, followed by a spread of recipients in California, Massachusetts, Pennsylvania, Connecticut, and other states.
It does not fund individuals. The grant list is made up of research awards to universities, medical schools, cancer centers, and research organizations, alongside fellowship programs for early-career scientists.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| UNIVERSITY OF PENNSYLVANIA | PHILADELPHIA, PA | $1,793,000 | 2025 | RESEARCH |
| YALE UNIVERSITY SCHOOL OF MEDICINE | NEW HAVEN, CT | $1,550,000 | 2025 | RESEARCH |
| COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | NEW YORK, NY | $1,250,000 | 2025 | RESEARCH |
| UNIVERSITY OF CALIFORNIA SAN FRANCISCO | SAN FRANCISCO, CA | $1,243,000 | 2025 | RESEARCH |
| MEMORIAL SLOAN KETTERING CANCER CENTER | NEW YORK, NY | $1,132,000 | 2025 | RESEARCH |
| BOSTON CHILDREN'S HOSPITAL | BOSTON, MA | $1,039,700 | 2025 | RESEARCH |
| THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER | HOUSTON, TX | $1,015,000 | 2025 | RESEARCH |
| THE ROCKEFELLER UNIVERSITY | NEW YORK, NY | $729,000 | 2025 | RESEARCH |
| STANFORD UNIVERSITY | STANFORD, CA | $729,000 | 2025 | RESEARCH |
| NEW YORK UNIVERSITY MEDICAL CENTER | NEW YORK, NY | $543,000 | 2025 | RESEARCH |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $300,000 | 2025 | RESEARCH |
| UNIVERSITY OF CHICAGO MEDICAL CENTER | CHICAGO, IL | $300,000 | 2025 | RESEARCH |
| OHIO STATE UNIVERSITY | COLUMBUS, OH | $300,000 | 2025 | RESEARCH |
| SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE | ST LOUIS, MO | $299,786 | 2025 | RESEARCH |
| NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES | BETHESDA, MD | $243,000 | 2025 | RESEARCH |
| EMORY UNIVERSITY | ATLANTA, GA | $243,000 | 2025 | RESEARCH |
| THE LA JOLLA INSTITUTE FOR IMMUNOLOGY | LA JOLLA, CA | $243,000 | 2025 | RESEARCH |
| ALBERT EINSTEIN COLLEGE OF MEDICINE | BRONX, NY | $243,000 | 2025 | RESEARCH |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | NEW YORK, NY | $243,000 | 2025 | RESEARCH |
| BROAD INSTITUTE OF MIT AND HARVARD | CAMBRIDGE, MA | $243,000 | 2025 | RESEARCH |
| WASHINGTON UNIVERSITY SCHOOL OF MEDICINE | ST LOUIS, MO | $243,000 | 2025 | RESEARCH |
| PRINCETON UNIVERSITY | PRINCETON, NJ | $243,000 | 2025 | RESEARCH |
| DANA-FARBER CANCER INSTITUTE INC | BOSTON, MA | $243,000 | 2025 | RESEARCH |
| UNIVERSITY OF MASSACHUSETTS CHAN MEDICAL SCHOOL | WORCESTER, MA | $243,000 | 2025 | RESEARCH |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | NEW YORK, NY | $243,000 | 2025 | RESEARCH |
| OVERT | NEW YORK, NY | $200,000 | 2025 | RESEARCH |
| THE J DAVID GLADSTONE INSTITUTES | SAN FRANCISCO, CA | $200,000 | 2025 | RESEARCH |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | BIRMINGHAM, AL | $200,000 | 2025 | RESEARCH |
| UNIVERSITY OF WASHINGTON | SEATTLE, WA | $160,000 | 2025 | RESEARCH |
| FRED HUTCHINSON CANCER RESEARCH CENTER | SEATTLE, WA | $67,700 | 2025 | RESEARCH |
| AMERICAN ASSOCIATION FOR CANCER RESEARCH | PHILADELPHIA, PA | $25,000 | 2025 | RESEARCH |
| FOCUSED ULTRASOUND FOUNDATION | CHARLOTTESVILLE, VA | $20,942 | 2025 | RESEARCH |
| THE BRIGHAM AND WOMEN'S HOSPITAL INC | BOSTON, MA | $6,361 | 2025 | RESEARCH |
| JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | BALTIMORE, MD | $9,002,197 | 2024 | RESEARCH |
| DANA-FARBER CANCER INSTITUTE INC | BOSTON, MA | $1,535,000 | 2024 | RESEARCH |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | NEW YORK, NY | $1,464,497 | 2024 | RESEARCH |
| EMORY UNIVERSITY | ATLANTA, GA | $1,250,000 | 2024 | RESEARCH |
| COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | NEW YORK, NY | $1,250,000 | 2024 | RESEARCH |
| UNIVERSITY OF CALIFORNIA SAN FRANCISCO | SAN FRANCISCO, CA | $1,128,550 | 2024 | RESEARCH |
| MEMORIAL SLOAN KETTERING CANCER CENTER | NEW YORK, NY | $1,112,850 | 2024 | RESEARCH |
| PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY | SAN FRANCISCO, CA | $750,000 | 2024 | RESEARCH |
| HARVARD UNIVERSITY | CAMBRIDGE, MA | $688,800 | 2024 | RESEARCH |
| YALE UNIVERSITY SCHOOL OF MEDICINE | NEW HAVEN, CT | $529,695 | 2024 | RESEARCH |
| BOSTON CHILDREN'S HOSPITAL | BOSTON, MA | $475,100 | 2024 | RESEARCH |
| UNIVERSITY OF MINNESOTA | MINNEAPOLIS, MN | $452,600 | 2024 | RESEARCH |
| THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | DALLAS, TX | $445,800 | 2024 | RESEARCH |
| BRIGHAM & WOMEN'S HOSPITALHARVARD MEDICAL SCHOOL | BOSTON, MA | $437,300 | 2024 | RESEARCH |
| UNIVERSITY OF WASHINGTON | SEATTLE, WA | $429,000 | 2024 | RESEARCH |
| OREGON HEALTH & SCIENCE UNIVERSITY | PORTLAND, OR | $405,600 | 2024 | RESEARCH |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $402,800 | 2024 | RESEARCH |
UNIVERSITY OF PENNSYLVANIA
$1,793,000RESEARCH
YALE UNIVERSITY SCHOOL OF MEDICINE
$1,550,000RESEARCH
COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
$1,250,000RESEARCH
UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$1,243,000RESEARCH
MEMORIAL SLOAN KETTERING CANCER CENTER
$1,132,000RESEARCH
BOSTON CHILDREN'S HOSPITAL
$1,039,700RESEARCH
THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER
$1,015,000RESEARCH
THE ROCKEFELLER UNIVERSITY
$729,000RESEARCH
STANFORD UNIVERSITY
$729,000RESEARCH
NEW YORK UNIVERSITY MEDICAL CENTER
$543,000RESEARCH
MASSACHUSETTS GENERAL HOSPITAL
$300,000RESEARCH
UNIVERSITY OF CHICAGO MEDICAL CENTER
$300,000RESEARCH
OHIO STATE UNIVERSITY
$300,000RESEARCH
SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE
$299,786RESEARCH
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
$243,000RESEARCH
EMORY UNIVERSITY
$243,000RESEARCH
THE LA JOLLA INSTITUTE FOR IMMUNOLOGY
$243,000RESEARCH
ALBERT EINSTEIN COLLEGE OF MEDICINE
$243,000RESEARCH
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
$243,000RESEARCH
BROAD INSTITUTE OF MIT AND HARVARD
$243,000RESEARCH
WASHINGTON UNIVERSITY SCHOOL OF MEDICINE
$243,000RESEARCH
PRINCETON UNIVERSITY
$243,000RESEARCH
DANA-FARBER CANCER INSTITUTE INC
$243,000RESEARCH
UNIVERSITY OF MASSACHUSETTS CHAN MEDICAL SCHOOL
$243,000RESEARCH
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
$243,000RESEARCH
OVERT
$200,000RESEARCH
THE J DAVID GLADSTONE INSTITUTES
$200,000RESEARCH
UNIVERSITY OF ALABAMA AT BIRMINGHAM
$200,000RESEARCH
UNIVERSITY OF WASHINGTON
$160,000RESEARCH
FRED HUTCHINSON CANCER RESEARCH CENTER
$67,700RESEARCH
AMERICAN ASSOCIATION FOR CANCER RESEARCH
$25,000RESEARCH
FOCUSED ULTRASOUND FOUNDATION
$20,942RESEARCH
THE BRIGHAM AND WOMEN'S HOSPITAL INC
$6,361RESEARCH
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
$9,002,197RESEARCH
DANA-FARBER CANCER INSTITUTE INC
$1,535,000RESEARCH
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
$1,464,497RESEARCH
EMORY UNIVERSITY
$1,250,000RESEARCH
COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
$1,250,000RESEARCH
UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$1,128,550RESEARCH
MEMORIAL SLOAN KETTERING CANCER CENTER
$1,112,850RESEARCH
PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY
$750,000RESEARCH
HARVARD UNIVERSITY
$688,800RESEARCH
YALE UNIVERSITY SCHOOL OF MEDICINE
$529,695RESEARCH
BOSTON CHILDREN'S HOSPITAL
$475,100RESEARCH
UNIVERSITY OF MINNESOTA
$452,600RESEARCH
THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER
$445,800RESEARCH
BRIGHAM & WOMEN'S HOSPITALHARVARD MEDICAL SCHOOL
$437,300RESEARCH
UNIVERSITY OF WASHINGTON
$429,000RESEARCH
OREGON HEALTH & SCIENCE UNIVERSITY
$405,600RESEARCH
MASSACHUSETTS GENERAL HOSPITAL
$402,800RESEARCH