About Mayo Clinic
Mayo Clinic has the vision and values to forever alter the trajectory of healthcare, ensuring high-quality, personalized care is accessible to everyone, everywhere.
Focus Areas
Medical researchPatient careMedical educationClinical trialsCommunity health
Who They Fund
unspecified
Funding Style
programmatic support (charitable)research program fundingproject-level grants
Topics
charitable program supportresearch program supportnon-thematic/general support
About Mayo Clinic
Mayo Clinic’s recent grantmaking is dominated by internal program support for its own healthcare network, with very large awards flowing to Mayo Clinic Jacksonville, Mayo Clinic Arizona, and Mayo Foundation for Medical Education and Research. Those grants show a structure built around sustaining clinical operations, education, and research inside the organization rather than dispersing funds broadly across many outside institutions. The scale is substantial: the foundation gave $1.77 billion in annual grants, and the largest recent award in the list was $346.1 million to Mayo Clinic Jacksonville in 2024 for support of charitable programs. Another major 2024 grant of $266.0 million went to Mayo Foundation for Medical Education and Research in Rochester for the same purpose. The pattern continues in 2025 with another $120.3 million to Mayo Clinic Jacksonville and $97.5 million to Mayo Clinic Arizona. Alongside these institutional commitments, Mayo Clinic also funds external research partners such as the University of California San Francisco and the Regents of the University of Minnesota.
What Mayo Clinic Funds
Medical research is one clear strand in Mayo Clinic’s giving. The foundation awarded $3,185,286 in 2025 to the University of California San Francisco for support of research programs, and it also gave $2,527,396 in 2023 and $1,960,832 in 2024 to the Regents of the University of Minnesota for the same purpose. A second area is clinical and charitable program support across Mayo-affiliated regions. Examples include $118,423,244 in 2025 to Mchs--southwest Minnesota Region and $95,970,322 in 2025 to Mchs--southwest Wisconsin Region Inc., both for support of charitable programs. Education appears in the organizational portfolio as well, reflected in the large grant to Mayo Foundation for Medical Education and Research. The portfolio also includes support for community-oriented regional entities such as Mchs--southeast Minnesota Region and Mchs--fairmont.
How Mayo Clinic Gives
Typical grants are mid-sized but with a wide spread: p25 is $20,350, median is $52,000, and p75 is $186,739. The recent list shows a strong recurring pattern, with many recipients appearing across 2023, 2024, and 2025, especially Mayo-affiliated regional entities and university research partners. Mayo Clinic is a public charity and a regular funder, and the grants shown are project-level and programmatic in nature, with a heavy emphasis on charitable program support and research program support. The organization does not fund individuals and does not make program-related investments.
Financial Snapshot
Annual Giving
$572.1M
Total Assets
$26.7B
Total Revenue
$7.9B
Total Expenses
$6.3B
Typical Grant Size
Most grants fall between $20K and $187K, with a median of $52K.
25th Percentile
$20K
Median
$52K
75th Percentile
$187K
Geographic Reach
National45 states funded
About 35% of grants go to recipients in DC.
Funding intensity
LowHigh
Headquarters
Leadership
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