The Crohn's & Colitis Foundation is primarily a biomedical research funder that supports investigator-initiated and translational research on inflammatory bowel disease by channeling multi-year and project grants to leading academic medical centers, pediatric hospitals, and specialized biotech partners. Its portfolio concentrates on clinical and translational studies, biomarker and therapeutic development, and pediatric IBD research, frequently supporting the same top research institutions repeatedly rather than broad community programming.
Crohn's & Colitis Foundation Inc. directs its grantmaking toward biomedical research on inflammatory bowel disease, with large awards flowing to academic medical centers, pediatric hospitals, and biotech partners. In the recent grants list, Weill Medical College of Cornell University received $926,360 in 2024 and $588,047 in 2023, showing repeat support for the same research institution. Other major awards went to Cincinnati Children's Hospital Medical Center for research and to Icahn School of Medicine at Mount Sinai, both part of a pattern of funding university-based clinical and translational work. The foundation also backs specialized industry collaborators such as Infinity Biologix LLC and Enlisense LLC, alongside established medical centers including Cedars Sinai Medical Center, Cleveland Clinic Foundation, and Washington University in St Louis. The overall picture is a funder that uses sizeable project grants to support investigator-initiated studies, biomarker and therapeutic development, and research infrastructure across a national network of IBD research institutions. Its giving is concentrated in the research ecosystem rather than broad community programming, and the same institutions appear repeatedly across multiple years.
Clinical and translational IBD research is a central theme. The foundation gave $1,017,114 in 2023 to Vanderbilt University Medical Center for research, and $692,063 in 2023 to The Regents of the University of California Los Angeles for research. Pediatric inflammatory bowel disease is another clear area: Boston Children's Hospital received $539,217 in 2024, and Cincinnati Children's Hospital Medical Center received $815,000 in 2024, both for research. The funder also supports therapeutic and biomarker development through specialized partners, including $661,903 in 2025 to Infinity Biologix LLC and $450,000 in 2024 to Enlisense LLC. Its portfolio includes multi-site academic research as well, with awards to The University of North Carolina at Chapel Hill, Case Western Reserve University - School of Medicine, and University of Maryland Baltimore.
Typical awards are mid-six figures: p25 is $57,910, median is $115,830, and p75 is $299,182. The recent list also shows repeated support for the same institutions across years, including Weill Medical College of Cornell University, Cedars Sinai Medical Center, Washington University in St Louis, University of Maryland Baltimore, and The Regents of the University of Michigan. That pattern fits a regular funder rather than a donor-advised vehicle. The foundation does not fund individuals and does not make program-related investments. Recent grants are all research grants, suggesting a project-oriented approach tied to institutional research activity rather than open application philanthropy.
$13M
$50.6M
$85.2M
$83.5M
Most grants fall between $58K and $299K, with a median of $116K.
25th Percentile
$58K
Median
$116K
75th Percentile
$299K
About 10% of grants go to recipients in CA.
MICHAEL OSSO
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Concentrated, research-focused giving: moderate number of relatively large grants distributed repeatedly to established academic medical centers and select biotech partners rather than many small community grants; emphasis on recurring support to institutional research programs and multi-year projects.
Notable grantees: Weill Medical College of Cornell University, Icahn School of Medicine at Mount Sinai, Vanderbilt University Medical Center, Boston Children's Hospital, Aetion Inc / Enlisenese (biotech partners)
Grantmaking is national, with recipients in 210 U.S. grants. Massachusetts is the top state by grant count, while New York accounts for 10% of grants and also appears repeatedly through New York City institutions such as Weill Medical College of Cornell University and Icahn School of Medicine at Mount Sinai. Other frequent recipient cities include Boston, Cincinnati, Los Angeles, Baltimore, and St Louis. The recipient-country distribution is entirely U.S.-based in the data provided.
It funds academic medical centers, pediatric hospitals, and specialized biotech partners. Recent recipients include universities and hospitals such as Vanderbilt University Medical Center, Boston Children's Hospital, and Cleveland Clinic Foundation, along with research companies such as Infinity Biologix LLC and Enlisense LLC.
The grant-size distribution is centered in the six-figure range. The p25 grant is $57,910, the median is $115,830, and the p75 is $299,182.
The recent grants list shows repeated support to the same organizations across multiple years. Weill Medical College of Cornell University, Cedars Sinai Medical Center, Washington University in St Louis, University of Maryland Baltimore, and The Regents of the University of Michigan each appear more than once.
Its giving is national, with all listed recipient-country grants in the U.S. Massachusetts is the top state by grant count, and New York represents 10% of grants.
The foundation funds clinical and translational inflammatory bowel disease research, pediatric IBD research, therapeutic development and biomarker work, multi-site investigator-initiated studies, and center-level research support at major medical centers.
2026
Source: IRS Form 990-PF, fiscal year 2026.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| INFINITY BIOLOGIX LLC | PISCATAWAY, NJ | $661,903 | 2026 | RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF MICHIGAN | ANN ARBOR, CO | $561,992 | 2026 | RESEARCH |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | NEW YORK, NY | $534,898 | 2026 | RESEARCH |
| MOBIUS CARE INC | CLEVELAND, OH | $500,000 | 2026 | RESEARCH |
| CEDARS SINAI MEDICAL CENTER | LOS ANGELES, CA | $426,341 | 2026 | RESEARCH |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | NEW YORK, NY | $407,003 | 2026 | RESEARCH |
| THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | PHILADELPHIA, MI | $388,114 | 2026 | RESEARCH |
| THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | CHAPEL HILL, IL | $384,631 | 2026 | RESEARCH |
| CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER | CINCINNATI, OH | $375,023 | 2026 | RESEARCH |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $362,986 | 2026 | RESEARCH |
| RUTGERS THE STATE UNIVERSITY OF NJ RUTGERS BIOMEDICAL & HEALTH SCIENCE | NEWARK, NJ | $316,168 | 2026 | RESEARCH |
| AETION INC | NEW YORK, NY | $315,500 | 2026 | RESEARCH |
| NORTHWESTERN UNIVERSITY FEINBERG SCHOOL OF MEDICINE | EVANSTON, IL | $301,544 | 2026 | RESEARCH |
| JOHNS HOPKINS UNIVERSITY | BALTIMORE, MD | $300,000 | 2026 | RESEARCH |
| CASE WESTERN RESERVE UNIVERSITY | CLEVELAND, OH | $288,165 | 2026 | RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN DIEGO | LA JOLLA, CA | $274,333 | 2026 | RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF COLORADO | AURORA, CA | $274,064 | 2026 | RESEARCH |
| BOSTON CHILDREN'S HOSPITAL | BOSTON, MA | $270,909 | 2026 | RESEARCH |
| HARVARD UNIVERSITY | CAMBRIDGE, MA | $269,495 | 2026 | RESEARCH |
| BAYLOR SCOTT & WHITE RESEARCH INSTITUTE | DALLAS, TX | $269,345 | 2026 | RESEARCH |
| WASHINGTON UNIVERSITY IN ST LOUIS (WASHINGTON UNIVERSITY) | ST LOUIS, MO | $267,385 | 2026 | RESEARCH |
| THE UNIVERSITY OF CHICAGO | CHICAGO, AZ | $259,430 | 2026 | RESEARCH |
| CLEVELAND CLINIC FOUNDATION | CLEVELAND, OH | $257,471 | 2026 | RESEARCH |
| OGB8 INC | CINCINNATI, OH | $250,000 | 2026 | RESEARCH |
| MAYO CLINIC COLLEGE OF MEDICINE | ROCHESTER, MN | $248,369 | 2026 | RESEARCH |
| ENLISENSE LLC | ALLEN, TX | $225,000 | 2026 | RESEARCH |
| VANDERBILT UNIVERSITY MEDICAL CENTER | NASHVILLE, TN | $212,166 | 2026 | RESEARCH |
| UNIVERSITY OF COLORADO DENVER | AURORA, CO | $210,476 | 2026 | RESEARCH |
| SERES THERAPEUTICS INC | CAMBRIDGE, MA | $200,000 | 2026 | RESEARCH |
| CHILDREN'S HOSPITAL LOS ANGELES | LOS ANGELES, CA | $195,000 | 2026 | RESEARCH |
| UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | PITTSBURGH, PA | $194,335 | 2026 | RESEARCH |
| UNIVERSITY OF MARYLAND BALTIMORE | BALTIMORE, MD | $179,201 | 2026 | RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES | LOS ANGELES, PA | $171,024 | 2026 | RESEARCH |
| BOARD OF REGENTS OF THE UNIVERSITY OF WISCONSIN SYSTEM - MEDICAL COLLEGE | MADISON, WI | $156,454 | 2026 | RESEARCH |
| THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (UT SOUTHWESTERN) | DALLAS, TX | $134,628 | 2026 | RESEARCH |
| UNIVERSITY OF FLORIDA | GAINESVILLE, FL | $130,000 | 2026 | RESEARCH |
| GLYCOMINDS LLC | SIMI VALLEY, CA | $126,000 | 2026 | RESEARCH |
| STANFORD UNIVERSITY | REDWOOD CITY, CA | $120,406 | 2026 | RESEARCH |
| INTEROPERABILITY BIDCO INC | BOSTON, MA | $117,659 | 2026 | RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO | SAN FRANCISCO, CA | $115,830 | 2026 | RESEARCH |
| BOARD OF REGENTS OF THE UNIVERSITY OF WISCONSIN SYSTEM | MADISON, WI | $115,709 | 2026 | RESEARCH |
| THE CHILDREN'S MERCY HOSPITAL | KANSAS CITY, MO | $101,684 | 2026 | RESEARCH |
| THE BRIGHAM AND WOMEN'S HOSPITAL INC | BOSTON, MA | $94,939 | 2026 | RESEARCH |
| THE UNIVERSITY OF ARIZONA | TUCSON, PA | $92,648 | 2026 | RESEARCH |
| DARTMOUTH-HITCHCOCK CLINIC | LEBANON, NH | $91,151 | 2026 | RESEARCH |
| AUGUSTA UNIVERSITY RESEARCH INSTITUTE INC | AUGUSTA, GA | $90,000 | 2026 | RESEARCH |
| NEW YORK UNIVERSITY GROSSMAN SCHOOL OF MEDICINE | NEW YORK, NY | $89,244 | 2026 | RESEARCH |
| UNIVERSITY OF CALIFORNIA SAN DIEGO | LA JOLLA, AL | $88,585 | 2026 | RESEARCH |
| ST PAUL PLACE SPECIALISTS INC | BALTIMORE, MD | $84,511 | 2026 | RESEARCH |
| THE CHILDREN'S HOSPITAL OF PHILADELPHIA | PHILADELPHIA, MA | $75,674 | 2026 | RESEARCH |
INFINITY BIOLOGIX LLC
$661,903RESEARCH
THE REGENTS OF THE UNIVERSITY OF MICHIGAN
$561,992RESEARCH
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
$534,898RESEARCH
MOBIUS CARE INC
$500,000RESEARCH
RESEARCH
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
$384,631RESEARCH
MASSACHUSETTS GENERAL HOSPITAL
$362,986RESEARCH
RUTGERS THE STATE UNIVERSITY OF NJ RUTGERS BIOMEDICAL & HEALTH SCIENCE
$316,168RESEARCH
AETION INC
$315,500RESEARCH
CASE WESTERN RESERVE UNIVERSITY
$288,165RESEARCH
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN DIEGO
$274,333RESEARCH
THE REGENTS OF THE UNIVERSITY OF COLORADO
$274,064RESEARCH
OGB8 INC
$250,000RESEARCH
ENLISENSE LLC
$225,000RESEARCH
UNIVERSITY OF COLORADO DENVER
$210,476RESEARCH
SERES THERAPEUTICS INC
$200,000RESEARCH
RESEARCH
UNIVERSITY OF MARYLAND BALTIMORE
$179,201RESEARCH
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES
$171,024RESEARCH
RESEARCH
THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (UT SOUTHWESTERN)
$134,628RESEARCH
UNIVERSITY OF FLORIDA
$130,000RESEARCH
GLYCOMINDS LLC
$126,000RESEARCH
INTEROPERABILITY BIDCO INC
$117,659RESEARCH
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$115,830RESEARCH
BOARD OF REGENTS OF THE UNIVERSITY OF WISCONSIN SYSTEM
$115,709RESEARCH
THE BRIGHAM AND WOMEN'S HOSPITAL INC
$94,939RESEARCH
THE UNIVERSITY OF ARIZONA
$92,648RESEARCH
UNIVERSITY OF CALIFORNIA SAN DIEGO
$88,585RESEARCH
ST PAUL PLACE SPECIALISTS INC
$84,511RESEARCH