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    Cancer Research Institute

    ActiveMedical Research
    NEW YORK, NYWebsite2126887515

    About Cancer Research Institute

    Uniting for a world immune to cancer by turning immunotherapy research into real-world impact and changing the way we treat and defeat cancer.

    Focus Areas

    Cancer immunotherapyClinical trials and translational researchImmunology and tumor immunologyData science and bioinformaticsTraining and career development for researchers

    Who They Fund

    cancer researchers (PIs and labs)postdoctoral and early-career scientistsclinical investigators and academic medical centersmultidisciplinary research consortia and expert networks

    Funding Style

    translational and clinical accelerationresearch capacity building

    About Cancer Research Institute

    Cancer Research Institute Inc backed a $9,002,197 grant to Johns Hopkins University School of Medicine in 2024, a signal of how much of its capital is directed toward research that can move immunotherapy into clinical use. The foundation’s giving is built around cancer immunotherapy, with support for multi-center clinical trials, translational research, data infrastructure, and career development for researchers. Its program mix reaches from early-stage ideas to late-stage clinical studies, including the CRI Anna-Maria Kellen Clinical Accelerator / Venture Philanthropy Fund and the CRI Lloyd J. Old STAR Program. It also funds investigator training through postdoctoral fellowships and transition awards, helping scientists build careers in immunology, bioinformatics, and cancer research. Recent grants show repeated support for major academic medical centers and research institutes, including University of California San Francisco, Dana-Farber Cancer Institute Inc, Memorial Sloan Kettering Cancer Center, and Columbia University in the City of New York. The pattern is one of sustained research funding rather than a single project category, with awards reaching across laboratory discovery, clinical translation, and shared data resources.

    What Cancer Research Institute Funds

    Cancer immunotherapy is the central thread across the foundation’s program portfolio. In clinical translation, it gave $1,000,000 to academic researchers through the CRI Clinical Innovator program for pioneering immunotherapy clinical trials, and $1,250,000 through the CRI Lloyd J. Old STAR Program for high-risk research at the leading edge of the field. It also supports the laboratory-to-clinic pipeline through the CRI Clinic and Laboratory Integration Program (CLIP), which funds investigations at the intersection of discovery and clinical application. On the data side, CRI Data Programs back AI-ready resources and shared tools, including the CRI Discovery Engine. Career-building is another recurring theme: the CRI Immuno-Informatics Postdoctoral Fellowship and the CRI Irvington Postdoctoral Fellowship support early-career scientists developing expertise in immunology, bioinformatics, and cancer immunology.

    How Cancer Research Institute Gives

    Typical award size clusters in the six-figure range, with p25 at $175,500, a median of $243,000, and p75 at $543,000. The recent grants list also shows several larger awards above $1 million, including multi-year support to research institutions and clinical programs. The foundation appears to combine recurring programmatic awards with one-off project grants, and some recipients appear in multiple years, such as University of California San Francisco, Columbia University in the City of New York, Yale University School of Medicine, and Memorial Sloan Kettering Cancer Center. It is a regular funder rather than a DAF, and it does not fund individuals. Several active programs accept unsolicited applications, including fellowships and research awards, while some data and accelerator programs do not.

    Financial Snapshot

    Annual Giving

    $15.8M

    Total Assets

    $133.7M

    Total Revenue

    $24M

    Total Expenses

    $32.8M

    Typical Grant Size

    Most grants fall between $176K and $543K, with a median of $243K.

    25th Percentile

    $176K

    Median

    $243K

    75th Percentile

    $543K

    Geographic Reach

    National22 states funded

    About 19% of grants go to recipients in NY.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

    ALICIA ZHOU PHD

    Accepts unsolicited proposals

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    EIN: 13-1837442
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    data and infrastructure funding
    convening and network building
    career development fellowships

    Topics

    cancer immunotherapyclinical trials and translational researchbasic cancer immunologybioinformatics and data programsspatial sequencing / spatial transcriptomicssingle-cell genomicstechnology-enabled research platforms

    Where Cancer Research Institute Makes Grants

    Grantmaking is national, and every grant in the recipient distribution is in the United States. New York is the top state by grant count, with 19% of grants going to recipients in NY, including New York City institutions such as Memorial Sloan Kettering Cancer Center, The Rockefeller University, and New York University Medical Center. Other recurring recipient cities include San Francisco, Boston, Philadelphia, New Haven, and Stanford. The list also reaches Baltimore, Seattle, Tampa, Atlanta, Houston, and Cambridge.

    Frequently Asked Questions About Cancer Research Institute

    What kinds of research does Cancer Research Institute Inc fund most often?

    Its active programs center on cancer immunotherapy, with support for clinical trials, translational research, immunology, bioinformatics, and shared data infrastructure. The portfolio includes the Clinical Accelerator / Venture Philanthropy Fund, postdoctoral fellowships, technology awards, and clinical innovation grants.

    Does Cancer Research Institute Inc accept unsolicited applications?

    Yes, several active programs do. The CRI Immuno-Informatics Postdoctoral Fellowship, CRI Irvington Postdoctoral Fellowship, CRI Technology Impact Award, CRI Lloyd J. Old STAR Program, CRI Clinical Innovator, CLIP, and CRI IGNITE Award all accept unsolicited applications.

    What is the typical grant size?

    Typical awards cluster around $243,000, with p25 at $175,500 and p75 at $543,000. The recent grants list also includes awards at $1,000,000, $1,250,000, and $9,002,197, showing that the foundation funds both mid-sized project grants and much larger institutional awards.

    Are the grants mostly in one place?

    The giving is national, and 100% of the recipient distribution is in the United States. New York receives the largest share of grants by count at 19%, followed by a spread of recipients in California, Massachusetts, Pennsylvania, Connecticut, and other states.

    Does the foundation fund people directly or only institutions?

    It does not fund individuals. The grant list is made up of research awards to universities, medical schools, cancer centers, and research organizations, alongside fellowship programs for early-career scientists.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    UNIVERSITY OF PENNSYLVANIAPHILADELPHIA, PA$1,793,0002025RESEARCH
    YALE UNIVERSITY SCHOOL OF MEDICINENEW HAVEN, CT$1,550,0002025RESEARCH
    COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKNEW YORK, NY$1,250,0002025RESEARCH
    UNIVERSITY OF CALIFORNIA SAN FRANCISCOSAN FRANCISCO, CA$1,243,0002025RESEARCH
    MEMORIAL SLOAN KETTERING CANCER CENTERNEW YORK, NY$1,132,0002025RESEARCH
    BOSTON CHILDREN'S HOSPITALBOSTON, MA$1,039,7002025RESEARCH
    THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTERHOUSTON, TX$1,015,0002025RESEARCH
    THE ROCKEFELLER UNIVERSITYNEW YORK, NY$729,0002025RESEARCH
    STANFORD UNIVERSITYSTANFORD, CA$729,0002025RESEARCH
    NEW YORK UNIVERSITY MEDICAL CENTERNEW YORK, NY$543,0002025RESEARCH
    MASSACHUSETTS GENERAL HOSPITALBOSTON, MA$300,0002025RESEARCH
    UNIVERSITY OF CHICAGO MEDICAL CENTERCHICAGO, IL$300,0002025RESEARCH
    OHIO STATE UNIVERSITYCOLUMBUS, OH$300,0002025RESEARCH
    SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINEST LOUIS, MO$299,7862025RESEARCH
    NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESBETHESDA, MD$243,0002025RESEARCH
    EMORY UNIVERSITYATLANTA, GA$243,0002025RESEARCH
    THE LA JOLLA INSTITUTE FOR IMMUNOLOGYLA JOLLA, CA$243,0002025RESEARCH
    ALBERT EINSTEIN COLLEGE OF MEDICINEBRONX, NY$243,0002025RESEARCH
    WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITYNEW YORK, NY$243,0002025RESEARCH
    BROAD INSTITUTE OF MIT AND HARVARDCAMBRIDGE, MA$243,0002025RESEARCH
    WASHINGTON UNIVERSITY SCHOOL OF MEDICINEST LOUIS, MO$243,0002025RESEARCH
    PRINCETON UNIVERSITYPRINCETON, NJ$243,0002025RESEARCH
    DANA-FARBER CANCER INSTITUTE INCBOSTON, MA$243,0002025RESEARCH
    UNIVERSITY OF MASSACHUSETTS CHAN MEDICAL SCHOOLWORCESTER, MA$243,0002025RESEARCH
    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAINEW YORK, NY$243,0002025RESEARCH
    OVERTNEW YORK, NY$200,0002025RESEARCH
    THE J DAVID GLADSTONE INSTITUTESSAN FRANCISCO, CA$200,0002025RESEARCH
    UNIVERSITY OF ALABAMA AT BIRMINGHAMBIRMINGHAM, AL$200,0002025RESEARCH
    UNIVERSITY OF WASHINGTONSEATTLE, WA$160,0002025RESEARCH
    FRED HUTCHINSON CANCER RESEARCH CENTERSEATTLE, WA$67,7002025RESEARCH
    AMERICAN ASSOCIATION FOR CANCER RESEARCHPHILADELPHIA, PA$25,0002025RESEARCH
    FOCUSED ULTRASOUND FOUNDATIONCHARLOTTESVILLE, VA$20,9422025RESEARCH
    THE BRIGHAM AND WOMEN'S HOSPITAL INCBOSTON, MA$6,3612025RESEARCH
    JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINEBALTIMORE, MD$9,002,1972024RESEARCH
    DANA-FARBER CANCER INSTITUTE INCBOSTON, MA$1,535,0002024RESEARCH
    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAINEW YORK, NY$1,464,4972024RESEARCH
    EMORY UNIVERSITYATLANTA, GA$1,250,0002024RESEARCH
    COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKNEW YORK, NY$1,250,0002024RESEARCH
    UNIVERSITY OF CALIFORNIA SAN FRANCISCOSAN FRANCISCO, CA$1,128,5502024RESEARCH
    MEMORIAL SLOAN KETTERING CANCER CENTERNEW YORK, NY$1,112,8502024RESEARCH
    PARKER INSTITUTE FOR CANCER IMMUNOTHERAPYSAN FRANCISCO, CA$750,0002024RESEARCH
    HARVARD UNIVERSITYCAMBRIDGE, MA$688,8002024RESEARCH
    YALE UNIVERSITY SCHOOL OF MEDICINENEW HAVEN, CT$529,6952024RESEARCH
    BOSTON CHILDREN'S HOSPITALBOSTON, MA$475,1002024RESEARCH
    UNIVERSITY OF MINNESOTAMINNEAPOLIS, MN$452,6002024RESEARCH
    THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTERDALLAS, TX$445,8002024RESEARCH
    BRIGHAM & WOMEN'S HOSPITALHARVARD MEDICAL SCHOOLBOSTON, MA$437,3002024RESEARCH
    UNIVERSITY OF WASHINGTONSEATTLE, WA$429,0002024RESEARCH
    OREGON HEALTH & SCIENCE UNIVERSITYPORTLAND, OR$405,6002024RESEARCH
    MASSACHUSETTS GENERAL HOSPITALBOSTON, MA$402,8002024RESEARCH

    UNIVERSITY OF PENNSYLVANIA

    $1,793,000
    PHILADELPHIA, PA2025

    RESEARCH

    YALE UNIVERSITY SCHOOL OF MEDICINE

    $1,550,000
    NEW HAVEN, CT2025

    RESEARCH

    COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

    $1,250,000
    NEW YORK, NY2025

    RESEARCH

    UNIVERSITY OF CALIFORNIA SAN FRANCISCO

    $1,243,000
    SAN FRANCISCO, CA2025

    RESEARCH

    MEMORIAL SLOAN KETTERING CANCER CENTER

    $1,132,000
    NEW YORK, NY2025

    RESEARCH

    BOSTON CHILDREN'S HOSPITAL

    $1,039,700
    BOSTON, MA2025

    RESEARCH

    THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER

    $1,015,000
    HOUSTON, TX2025

    RESEARCH

    THE ROCKEFELLER UNIVERSITY

    $729,000
    NEW YORK, NY2025

    RESEARCH

    STANFORD UNIVERSITY

    $729,000
    STANFORD, CA2025

    RESEARCH

    NEW YORK UNIVERSITY MEDICAL CENTER

    $543,000
    NEW YORK, NY2025

    RESEARCH

    MASSACHUSETTS GENERAL HOSPITAL

    $300,000
    BOSTON, MA2025

    RESEARCH

    UNIVERSITY OF CHICAGO MEDICAL CENTER

    $300,000
    CHICAGO, IL2025

    RESEARCH

    OHIO STATE UNIVERSITY

    $300,000
    COLUMBUS, OH2025

    RESEARCH

    SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE

    $299,786
    ST LOUIS, MO2025

    RESEARCH

    NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

    $243,000
    BETHESDA, MD2025

    RESEARCH

    EMORY UNIVERSITY

    $243,000
    ATLANTA, GA2025

    RESEARCH

    THE LA JOLLA INSTITUTE FOR IMMUNOLOGY

    $243,000
    LA JOLLA, CA2025

    RESEARCH

    ALBERT EINSTEIN COLLEGE OF MEDICINE

    $243,000
    BRONX, NY2025

    RESEARCH

    WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY

    $243,000
    NEW YORK, NY2025

    RESEARCH

    BROAD INSTITUTE OF MIT AND HARVARD

    $243,000
    CAMBRIDGE, MA2025

    RESEARCH

    WASHINGTON UNIVERSITY SCHOOL OF MEDICINE

    $243,000
    ST LOUIS, MO2025

    RESEARCH

    PRINCETON UNIVERSITY

    $243,000
    PRINCETON, NJ2025

    RESEARCH

    DANA-FARBER CANCER INSTITUTE INC

    $243,000
    BOSTON, MA2025

    RESEARCH

    UNIVERSITY OF MASSACHUSETTS CHAN MEDICAL SCHOOL

    $243,000
    WORCESTER, MA2025

    RESEARCH

    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

    $243,000
    NEW YORK, NY2025

    RESEARCH

    OVERT

    $200,000
    NEW YORK, NY2025

    RESEARCH

    THE J DAVID GLADSTONE INSTITUTES

    $200,000
    SAN FRANCISCO, CA2025

    RESEARCH

    UNIVERSITY OF ALABAMA AT BIRMINGHAM

    $200,000
    BIRMINGHAM, AL2025

    RESEARCH

    UNIVERSITY OF WASHINGTON

    $160,000
    SEATTLE, WA2025

    RESEARCH

    FRED HUTCHINSON CANCER RESEARCH CENTER

    $67,700
    SEATTLE, WA2025

    RESEARCH

    AMERICAN ASSOCIATION FOR CANCER RESEARCH

    $25,000
    PHILADELPHIA, PA2025

    RESEARCH

    FOCUSED ULTRASOUND FOUNDATION

    $20,942
    CHARLOTTESVILLE, VA2025

    RESEARCH

    THE BRIGHAM AND WOMEN'S HOSPITAL INC

    $6,361
    BOSTON, MA2025

    RESEARCH

    JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE

    $9,002,197
    BALTIMORE, MD2024

    RESEARCH

    DANA-FARBER CANCER INSTITUTE INC

    $1,535,000
    BOSTON, MA2024

    RESEARCH

    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

    $1,464,497
    NEW YORK, NY2024

    RESEARCH

    EMORY UNIVERSITY

    $1,250,000
    ATLANTA, GA2024

    RESEARCH

    COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

    $1,250,000
    NEW YORK, NY2024

    RESEARCH

    UNIVERSITY OF CALIFORNIA SAN FRANCISCO

    $1,128,550
    SAN FRANCISCO, CA2024

    RESEARCH

    MEMORIAL SLOAN KETTERING CANCER CENTER

    $1,112,850
    NEW YORK, NY2024

    RESEARCH

    PARKER INSTITUTE FOR CANCER IMMUNOTHERAPY

    $750,000
    SAN FRANCISCO, CA2024

    RESEARCH

    HARVARD UNIVERSITY

    $688,800
    CAMBRIDGE, MA2024

    RESEARCH

    YALE UNIVERSITY SCHOOL OF MEDICINE

    $529,695
    NEW HAVEN, CT2024

    RESEARCH

    BOSTON CHILDREN'S HOSPITAL

    $475,100
    BOSTON, MA2024

    RESEARCH

    UNIVERSITY OF MINNESOTA

    $452,600
    MINNEAPOLIS, MN2024

    RESEARCH

    THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

    $445,800
    DALLAS, TX2024

    RESEARCH

    BRIGHAM & WOMEN'S HOSPITALHARVARD MEDICAL SCHOOL

    $437,300
    BOSTON, MA2024

    RESEARCH

    UNIVERSITY OF WASHINGTON

    $429,000
    SEATTLE, WA2024

    RESEARCH

    OREGON HEALTH & SCIENCE UNIVERSITY

    $405,600
    PORTLAND, OR2024

    RESEARCH

    MASSACHUSETTS GENERAL HOSPITAL

    $402,800
    BOSTON, MA2024

    RESEARCH