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    5. Chadtough Defeat Dipg Foundation
    Chadtough Defeat Dipg Foundation logo

    Chadtough Defeat Dipg Foundation

    ActiveHuman Services
    SALINE, MIWebsite7347078732

    About Chadtough Defeat Dipg Foundation

    Dedicated to advancing promising scientific discoveries and funding research to find a cure for DIPG/DMG while supporting affected families.

    Focus Areas

    Diffuse Intrinsic Pontine Glioma (DIPG)Diffuse Midline Glioma (DMG)Pediatric brain cancer researchFellowships and investigator supportTranslational and clinical research

    Who They Fund

    children with DIPG (pediatric patients)pediatric neuro-oncology researchers and clinician-scientists

    Funding Style

    targeted/project-specific research fundingdisease-focused grantsbiomedical/clinical research support

    About Chadtough Defeat Dipg Foundation

    Chadtough Defeat Dipg Foundation centers its grantmaking on research to find a cure for DIPG and DMG, with support extending to affected families. Its recent awards show a strong preference for scientific and clinical work at major research institutions, including a $1,629,755 grant to the University of Michigan and a $1,047,540 grant to the University of California, San Francisco. Other large awards have gone to Dana-Farber Cancer Institute, Duke University, Massachusetts Institute of Technology, and MD Anderson Cancer Center, indicating a portfolio built around pediatric brain cancer research rather than general health funding. The foundation’s program language emphasizes investigator-led projects, fellowships, translational research, and clinical studies. That mix fits a targeted disease-focused strategy: funding individual scientists, supporting collaborative or sponsored projects, and backing work that aims to move from laboratory findings toward treatment. Its named program pages include research grants, fellowship awards, special grants, and game changer awards, all tied to DIPG/DMG. The recipient list is concentrated in established academic medical centers, with repeated support for institutions that can carry out preclinical and translational neuro-oncology research.

    What Chadtough Defeat Dipg Foundation Funds

    In pediatric brain cancer research, the foundation gave $588,997 to the University of Michigan for research specific to DIPG, after a prior $435,528 award to the Regents of the University of Michigan for the same disease focus. It also supported Dana-Farber Cancer Institute with $385,696 in 2024 for pediatric brain cancer research specific to DIPG, showing sustained interest in institution-based scientific programs. Its portfolio also includes translational and therapeutic work. A $382,900 research grant to Duke University and a $382,560 grant to Massachusetts Institute of Technology both sit within broader research support tied to DIPG. The foundation has also funded projects on immunotherapy and mitochondrial biology, including work described as inhibition of mitochondrial ROS scavenging as a treatment strategy for DMG. Fellowship support is another clear theme. The foundation’s fellowship grant program is designed for pre-doctoral and post-doctoral fellows under mentor guidance, pointing to talent development alongside project funding.

    How Chadtough Defeat Dipg Foundation Gives

    Financial Snapshot

    Annual Giving

    $6.3M

    Total Assets

    $9.4M

    Total Revenue

    $7.5M

    Total Expenses

    $9.8M

    Typical Grant Size

    Most grants fall between $100K and $200K, with a median of $125K.

    25th Percentile

    $100K

    Median

    $125K

    75th Percentile

    $200K

    Geographic Reach

    National19 states funded

    About 5% of grants go to recipients in CA.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

    ANN FRIEDHOLM

    Accepts unsolicited proposals

    Deep Analysis

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    EIN (Tax ID): 47-4041494Latest Form 990: 2026Total assets: $9.4M4 filings on recordFind their full 990 filing →
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    competitive research grants

    Topics

    DIPG (diffuse intrinsic pontine glioma) researchpediatric brain tumor biologydevelopment of DIPG therapeutics/clinical trialstranslational pediatric neuro-oncology researchpreclinical modeling for DIPG

    Typical grant size falls between $99,516 at the 25th percentile and $200,000 at the 75th percentile, with a median of $125,000. The recent list also shows a wide upper tier, including multi-million-dollar research grants to major universities and hospitals. The foundation is a regular funder and a DAF classification of Regular Funder is listed. Its site includes competitive research grants, fellowship awards, special grants, and project-specific awards, and several program pages note that unsolicited applications are accepted. The recent grant list shows repeat support for the same institutions across multiple years, suggesting recurring relationships rather than isolated one-time awards.

    Where Chadtough Defeat Dipg Foundation Makes Grants

    Grantmaking is national, and every recent grant listed went to U.S. recipients. Massachusetts appears frequently in the recipient list, with awards to Boston and Cambridge institutions such as Dana-Farber Cancer Institute, Broad Institute, and Harvard. Other repeated recipient cities include Ann Arbor, Houston, New York, and San Francisco. The foundation gives in Michigan as well, but only 6% of grants go to recipients in the HQ state, which is far below the national spread of its awards.

    Frequently Asked Questions About Chadtough Defeat Dipg Foundation

    What kinds of research does Chadtough Defeat Dipg Foundation fund?

    Its stated focus is DIPG and DMG research, including pediatric brain cancer research, fellowship and investigator support, translational research, and clinical research. The recent grants also show work tied to preclinical studies, therapeutic development, immunotherapy, and mitochondrial biology.

    What is the foundation’s typical grant size?

    The grant-size distribution centers around six figures: the 25th percentile is $99,516, the median is $125,000, and the 75th percentile is $200,000. The recent awards also include several larger research grants above $1 million.

    Does the foundation accept unsolicited proposals?

    Yes. Multiple active program pages note that unsolicited applications are accepted, including the Investigator Grant, Special Grant, Fellowship Grant, ChadTough Research Grants, and several project-specific funding pages.

    Does the foundation fund only U.S. organizations?

    No. The main recent-grant list is entirely U.S.-based, but the active program description for ChadTough Research Grants says geography can include the United States and international recipients on a case-by-case basis. The fellowship grant program is listed as global.

    Are grants usually one-time awards or repeated relationships?

    The recent grants show repeated funding to the same institutions across multiple years. University of Michigan and Dana-Farber Cancer Institute each appear more than once, and the University of California San Francisco also appears in more than one year, indicating recurring relationships.

    Latest 990 Filing

    2026

    Source: IRS Form 990-PF, fiscal year 2026.

    Open Grant Opportunities

    Current and upcoming funding from Chadtough Defeat Dipg Foundation that your nonprofit may be able to apply for.

    Opening soonLOI due Jan 11, 2027Closes Mar 31, 2027Award: Up to $400K

    New Investigator Grant (ChadTough Defeat DIPG Foundation)

    DIPG/DMG researchPediatric brain cancerNew investigator support+2 more

    Who can apply: Newly independent DIPG/DMG researchers working to establish DIPG/DMG research laboratories, or established researchers who have not previously conducted DIPG/DMG research and are seeking to begin such research.

    Deadline: Opens October 16, 2026; LOI due January 11, 2027; invitations for full submission February 24, 2027; full application due March 31, 2027; awards June 2027; grant start August 1, 2027.

    View & apply

    Track these deadlines, get reminders, and see how well your nonprofit fits — free with a Kindora account.

    Create a free account

    Deadlines and eligibility are summarized from public sources and may change — always confirm the details on the funder's official application page before applying.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    UNIVERSITY OF MICHIGANANN ARBOR, MI$1,629,7552026RESEARCH GRANT
    UNIVERSITY OF CALIFORNIASAN FRANCISCO, CA$1,047,5402026RESEARCH GRANT
    DANA-FARBER CANCER INSTITUTE INCBOSTON, MA$601,5002026RESEARCH GRANT
    DUKE UNIVERSITYDURHAM, NC$382,9002026RESEARCH GRANT
    MASSACHUSETTS INSTITUTE OF TECHNOLOCAMBRIDGE, MA$382,5602026RESEARCH GRANT
    METHODIST HOSPITAL RESEARCH INSTITUHOUSTON, TX$366,6902026RESEARCH GRANT
    MD ANDERSON CANCERHOUSTON, TX$289,4252026RESEARCH GRANT
    COLUMBIA UNIVERSITYNEW YORK, NY$287,6502026RESEARCH GRANT
    BROAD INSTITUTECAMBRIDGE, MA$270,5602026RESEARCH GRANT
    SEATTLE CHILDREN'S HOSPITALSEATTLE, WA$255,0582026RESEARCH GRANT
    WASHINGTON UNIVERSITYST LOUIS, MO$233,8902026RESEARCH GRANT
    UNIVERSITY OF MINNESOTAMINNEAPOLIS, MN$176,2602026RESEARCH GRANT
    PRESIDENT & FELLOWS OF HARVARD COLCAMBRIDGE, MA$150,5102026RESEARCH GRANT
    UNIVERSITY OF VERMONT & STATE AGRIBURLINGTON, VT$121,1042026RESEARCH GRANT
    LUCILE PACKARD CHILDREN'S HOSPITALPALO ALTO, CA$29,5782026RESEARCH GRANTS
    STANFORD UNIVERSITYSTANFORD, CA$13,5122026RESEARCH GRANTS
    CINCINNATI CHILDREN'SCINCINNATI, OH$12,6832026RESEARCH GRANT
    ICAHN SCHOOL OF MEDICINENEW YORK, NY$12,2402026RESEARCH GRANT
    WEILL MEDICAL COLLEGE OF CORNELLNEW YORK, NY$11,4442026RESEARCH GRANT
    BAYLOR COLLEGE OF MEDICINEHOUSTON, TX$8,0802026RESEARCH GRANT
    UNIVERSITY OF FLORIDAGAINESVILLE, FL$7,8532026RESEARCH GRANTS
    SANFORD BURNHAM PREBYS MEDICALLA JOLLA, CA$7,4262026RESEARCH GRANTS
    PURDUE UNIVERSITYWEST LAFAYETTE, IN$5,4542026RESEARCH GRANTS
    UNIVERSITY OF MICHIGANANN ARBOR, MI$1,629,7552025RESEARCH GRANT
    UNIVERSITY OF CALIFORNIASAN FRANCISCO, CA$1,047,5402025RESEARCH GRANT
    DANA-FARBER CANCER INSTITUTE INCBOSTON, MA$601,5002025RESEARCH GRANT
    DUKE UNIVERSITYDURHAM, NC$382,9002025RESEARCH GRANT
    MASSACHUSETTS INSTITUTE OF TECHNOLOCAMBRIDGE, MA$382,5602025RESEARCH GRANT
    METHODIST HOSPITAL RESEARCH INSTITUHOUSTON, TX$366,6902025RESEARCH GRANT
    MD ANDERSON CANCERHOUSTON, TX$289,4252025RESEARCH GRANT
    COLUMBIA UNIVERSITYNEW YORK, NY$287,6502025RESEARCH GRANT
    BROAD INSTITUTECAMBRIDGE, MA$270,5602025RESEARCH GRANT
    SEATTLE CHILDREN'S HOSPITALSEATTLE, WA$255,0582025RESEARCH GRANT
    WASHINGTON UNIVERSITYST LOUIS, MO$233,8902025RESEARCH GRANT
    UNIVERSITY OF MINNESOTAMINNEAPOLIS, MN$176,2602025RESEARCH GRANT
    PRESIDENT & FELLOWS OF HARVARD COLCAMBRIDGE, MA$150,5102025RESEARCH GRANT
    UNIVERSITY OF VERMONT & STATE AGRIBURLINGTON, VT$121,1042025RESEARCH GRANT
    LUCILE PACKARD CHILDREN'S HOSPITALPALO ALTO, CA$29,5782025RESEARCH GRANTS
    STANFORD UNIVERSITYSTANFORD, CA$13,5122025RESEARCH GRANTS
    CINCINNATI CHILDREN'SCINCINNATI, OH$12,6832025RESEARCH GRANT
    ICAHN SCHOOL OF MEDICINENEW YORK, NY$12,2402025RESEARCH GRANT
    WEILL MEDICAL COLLEGE OF CORNELLNEW YORK, NY$11,4442025RESEARCH GRANT
    BAYLOR COLLEGE OF MEDICINEHOUSTON, TX$8,0802025RESEARCH GRANT
    UNIVERSITY OF FLORIDAGAINESVILLE, FL$7,8532025RESEARCH GRANTS
    SANFORD BURNHAM PREBYS MEDICALLA JOLLA, CA$7,4262025RESEARCH GRANTS
    PURDUE UNIVERSITYWEST LAFAYETTE, IN$5,4542025RESEARCH GRANTS
    UNIVERSITY OF MICHIGANANN ARBOR, MI$588,9972024PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
    DANA-FARBER CANCER INSTITUTE INCBOSTON, MA$385,6962024PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
    LUCILE PACKARD FOUNDATION FOR CHILDREN'S HEALTHPALO ALTO, CA$334,5002024PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
    THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYSTANFORD, CA$327,7502024PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG

    UNIVERSITY OF MICHIGAN

    $1,629,755
    ANN ARBOR, MI2026

    RESEARCH GRANT

    UNIVERSITY OF CALIFORNIA

    $1,047,540
    SAN FRANCISCO, CA2026

    RESEARCH GRANT

    DANA-FARBER CANCER INSTITUTE INC

    $601,500
    BOSTON, MA2026

    RESEARCH GRANT

    DUKE UNIVERSITY

    $382,900
    DURHAM, NC2026

    RESEARCH GRANT

    MASSACHUSETTS INSTITUTE OF TECHNOLO

    $382,560
    CAMBRIDGE, MA2026

    RESEARCH GRANT

    METHODIST HOSPITAL RESEARCH INSTITU

    $366,690
    HOUSTON, TX2026

    RESEARCH GRANT

    MD ANDERSON CANCER

    $289,425
    HOUSTON, TX2026

    RESEARCH GRANT

    COLUMBIA UNIVERSITY

    $287,650
    NEW YORK, NY2026

    RESEARCH GRANT

    BROAD INSTITUTE

    $270,560
    CAMBRIDGE, MA2026

    RESEARCH GRANT

    SEATTLE CHILDREN'S HOSPITAL

    $255,058
    SEATTLE, WA2026

    RESEARCH GRANT

    WASHINGTON UNIVERSITY

    $233,890
    ST LOUIS, MO2026

    RESEARCH GRANT

    UNIVERSITY OF MINNESOTA

    $176,260
    MINNEAPOLIS, MN2026

    RESEARCH GRANT

    PRESIDENT & FELLOWS OF HARVARD COL

    $150,510
    CAMBRIDGE, MA2026

    RESEARCH GRANT

    UNIVERSITY OF VERMONT & STATE AGRI

    $121,104
    BURLINGTON, VT2026

    RESEARCH GRANT

    LUCILE PACKARD CHILDREN'S HOSPITAL

    $29,578
    PALO ALTO, CA2026

    RESEARCH GRANTS

    STANFORD UNIVERSITY

    $13,512
    STANFORD, CA2026

    RESEARCH GRANTS

    CINCINNATI CHILDREN'S

    $12,683
    CINCINNATI, OH2026

    RESEARCH GRANT

    ICAHN SCHOOL OF MEDICINE

    $12,240
    NEW YORK, NY2026

    RESEARCH GRANT

    WEILL MEDICAL COLLEGE OF CORNELL

    $11,444
    NEW YORK, NY2026

    RESEARCH GRANT

    BAYLOR COLLEGE OF MEDICINE

    $8,080
    HOUSTON, TX2026

    RESEARCH GRANT

    UNIVERSITY OF FLORIDA

    $7,853
    GAINESVILLE, FL2026

    RESEARCH GRANTS

    SANFORD BURNHAM PREBYS MEDICAL

    $7,426
    LA JOLLA, CA2026

    RESEARCH GRANTS

    PURDUE UNIVERSITY

    $5,454
    WEST LAFAYETTE, IN2026

    RESEARCH GRANTS

    UNIVERSITY OF MICHIGAN

    $1,629,755
    ANN ARBOR, MI2025

    RESEARCH GRANT

    UNIVERSITY OF CALIFORNIA

    $1,047,540
    SAN FRANCISCO, CA2025

    RESEARCH GRANT

    DANA-FARBER CANCER INSTITUTE INC

    $601,500
    BOSTON, MA2025

    RESEARCH GRANT

    DUKE UNIVERSITY

    $382,900
    DURHAM, NC2025

    RESEARCH GRANT

    MASSACHUSETTS INSTITUTE OF TECHNOLO

    $382,560
    CAMBRIDGE, MA2025

    RESEARCH GRANT

    METHODIST HOSPITAL RESEARCH INSTITU

    $366,690
    HOUSTON, TX2025

    RESEARCH GRANT

    MD ANDERSON CANCER

    $289,425
    HOUSTON, TX2025

    RESEARCH GRANT

    COLUMBIA UNIVERSITY

    $287,650
    NEW YORK, NY2025

    RESEARCH GRANT

    BROAD INSTITUTE

    $270,560
    CAMBRIDGE, MA2025

    RESEARCH GRANT

    SEATTLE CHILDREN'S HOSPITAL

    $255,058
    SEATTLE, WA2025

    RESEARCH GRANT

    WASHINGTON UNIVERSITY

    $233,890
    ST LOUIS, MO2025

    RESEARCH GRANT

    UNIVERSITY OF MINNESOTA

    $176,260
    MINNEAPOLIS, MN2025

    RESEARCH GRANT

    PRESIDENT & FELLOWS OF HARVARD COL

    $150,510
    CAMBRIDGE, MA2025

    RESEARCH GRANT

    UNIVERSITY OF VERMONT & STATE AGRI

    $121,104
    BURLINGTON, VT2025

    RESEARCH GRANT

    LUCILE PACKARD CHILDREN'S HOSPITAL

    $29,578
    PALO ALTO, CA2025

    RESEARCH GRANTS

    STANFORD UNIVERSITY

    $13,512
    STANFORD, CA2025

    RESEARCH GRANTS

    CINCINNATI CHILDREN'S

    $12,683
    CINCINNATI, OH2025

    RESEARCH GRANT

    ICAHN SCHOOL OF MEDICINE

    $12,240
    NEW YORK, NY2025

    RESEARCH GRANT

    WEILL MEDICAL COLLEGE OF CORNELL

    $11,444
    NEW YORK, NY2025

    RESEARCH GRANT

    BAYLOR COLLEGE OF MEDICINE

    $8,080
    HOUSTON, TX2025

    RESEARCH GRANT

    UNIVERSITY OF FLORIDA

    $7,853
    GAINESVILLE, FL2025

    RESEARCH GRANTS

    SANFORD BURNHAM PREBYS MEDICAL

    $7,426
    LA JOLLA, CA2025

    RESEARCH GRANTS

    PURDUE UNIVERSITY

    $5,454
    WEST LAFAYETTE, IN2025

    RESEARCH GRANTS

    UNIVERSITY OF MICHIGAN

    $588,997
    ANN ARBOR, MI2024

    PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG

    DANA-FARBER CANCER INSTITUTE INC

    $385,696
    BOSTON, MA2024

    PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG

    LUCILE PACKARD FOUNDATION FOR CHILDREN'S HEALTH

    $334,500
    PALO ALTO, CA2024

    PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG

    THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

    $327,750
    STANFORD, CA2024

    PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG