Dedicated to advancing promising scientific discoveries and funding research to find a cure for DIPG/DMG while supporting affected families.
Chadtough Defeat Dipg Foundation centers its grantmaking on research to find a cure for DIPG and DMG, with support extending to affected families. Its recent awards show a strong preference for scientific and clinical work at major research institutions, including a $1,629,755 grant to the University of Michigan and a $1,047,540 grant to the University of California, San Francisco. Other large awards have gone to Dana-Farber Cancer Institute, Duke University, Massachusetts Institute of Technology, and MD Anderson Cancer Center, indicating a portfolio built around pediatric brain cancer research rather than general health funding. The foundation’s program language emphasizes investigator-led projects, fellowships, translational research, and clinical studies. That mix fits a targeted disease-focused strategy: funding individual scientists, supporting collaborative or sponsored projects, and backing work that aims to move from laboratory findings toward treatment. Its named program pages include research grants, fellowship awards, special grants, and game changer awards, all tied to DIPG/DMG. The recipient list is concentrated in established academic medical centers, with repeated support for institutions that can carry out preclinical and translational neuro-oncology research.
In pediatric brain cancer research, the foundation gave $588,997 to the University of Michigan for research specific to DIPG, after a prior $435,528 award to the Regents of the University of Michigan for the same disease focus. It also supported Dana-Farber Cancer Institute with $385,696 in 2024 for pediatric brain cancer research specific to DIPG, showing sustained interest in institution-based scientific programs. Its portfolio also includes translational and therapeutic work. A $382,900 research grant to Duke University and a $382,560 grant to Massachusetts Institute of Technology both sit within broader research support tied to DIPG. The foundation has also funded projects on immunotherapy and mitochondrial biology, including work described as inhibition of mitochondrial ROS scavenging as a treatment strategy for DMG. Fellowship support is another clear theme. The foundation’s fellowship grant program is designed for pre-doctoral and post-doctoral fellows under mentor guidance, pointing to talent development alongside project funding.
$6.3M
$9.4M
$7.5M
$9.8M
Most grants fall between $100K and $200K, with a median of $125K.
25th Percentile
$100K
Median
$125K
75th Percentile
$200K
About 5% of grants go to recipients in CA.
ANN FRIEDHOLM
Sign up for a free Kindora account to access AI-generated insights into this funder's giving patterns, decision-makers, and fit signals.
Get Started FreeFree Kindora accounts unlock side-by-side comparisons with foundations that share this funder's focus areas and giving profile.
Get Started FreeSign up free to see how well your nonprofit fits this funder, get an AI-generated pitch, and unlock similar foundations.
Typical grant size falls between $99,516 at the 25th percentile and $200,000 at the 75th percentile, with a median of $125,000. The recent list also shows a wide upper tier, including multi-million-dollar research grants to major universities and hospitals. The foundation is a regular funder and a DAF classification of Regular Funder is listed. Its site includes competitive research grants, fellowship awards, special grants, and project-specific awards, and several program pages note that unsolicited applications are accepted. The recent grant list shows repeat support for the same institutions across multiple years, suggesting recurring relationships rather than isolated one-time awards.
Grantmaking is national, and every recent grant listed went to U.S. recipients. Massachusetts appears frequently in the recipient list, with awards to Boston and Cambridge institutions such as Dana-Farber Cancer Institute, Broad Institute, and Harvard. Other repeated recipient cities include Ann Arbor, Houston, New York, and San Francisco. The foundation gives in Michigan as well, but only 6% of grants go to recipients in the HQ state, which is far below the national spread of its awards.
Its stated focus is DIPG and DMG research, including pediatric brain cancer research, fellowship and investigator support, translational research, and clinical research. The recent grants also show work tied to preclinical studies, therapeutic development, immunotherapy, and mitochondrial biology.
The grant-size distribution centers around six figures: the 25th percentile is $99,516, the median is $125,000, and the 75th percentile is $200,000. The recent awards also include several larger research grants above $1 million.
Yes. Multiple active program pages note that unsolicited applications are accepted, including the Investigator Grant, Special Grant, Fellowship Grant, ChadTough Research Grants, and several project-specific funding pages.
No. The main recent-grant list is entirely U.S.-based, but the active program description for ChadTough Research Grants says geography can include the United States and international recipients on a case-by-case basis. The fellowship grant program is listed as global.
The recent grants show repeated funding to the same institutions across multiple years. University of Michigan and Dana-Farber Cancer Institute each appear more than once, and the University of California San Francisco also appears in more than one year, indicating recurring relationships.
2026
Source: IRS Form 990-PF, fiscal year 2026.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $1,629,755 | 2026 | RESEARCH GRANT |
| UNIVERSITY OF CALIFORNIA | SAN FRANCISCO, CA | $1,047,540 | 2026 | RESEARCH GRANT |
| DANA-FARBER CANCER INSTITUTE INC | BOSTON, MA | $601,500 | 2026 | RESEARCH GRANT |
| DUKE UNIVERSITY | DURHAM, NC | $382,900 | 2026 | RESEARCH GRANT |
| MASSACHUSETTS INSTITUTE OF TECHNOLO | CAMBRIDGE, MA | $382,560 | 2026 | RESEARCH GRANT |
| METHODIST HOSPITAL RESEARCH INSTITU | HOUSTON, TX | $366,690 | 2026 | RESEARCH GRANT |
| MD ANDERSON CANCER | HOUSTON, TX | $289,425 | 2026 | RESEARCH GRANT |
| COLUMBIA UNIVERSITY | NEW YORK, NY | $287,650 | 2026 | RESEARCH GRANT |
| BROAD INSTITUTE | CAMBRIDGE, MA | $270,560 | 2026 | RESEARCH GRANT |
| SEATTLE CHILDREN'S HOSPITAL | SEATTLE, WA | $255,058 | 2026 | RESEARCH GRANT |
| WASHINGTON UNIVERSITY | ST LOUIS, MO | $233,890 | 2026 | RESEARCH GRANT |
| UNIVERSITY OF MINNESOTA | MINNEAPOLIS, MN | $176,260 | 2026 | RESEARCH GRANT |
| PRESIDENT & FELLOWS OF HARVARD COL | CAMBRIDGE, MA | $150,510 | 2026 | RESEARCH GRANT |
| UNIVERSITY OF VERMONT & STATE AGRI | BURLINGTON, VT | $121,104 | 2026 | RESEARCH GRANT |
| LUCILE PACKARD CHILDREN'S HOSPITAL | PALO ALTO, CA | $29,578 | 2026 | RESEARCH GRANTS |
| STANFORD UNIVERSITY | STANFORD, CA | $13,512 | 2026 | RESEARCH GRANTS |
| CINCINNATI CHILDREN'S | CINCINNATI, OH | $12,683 | 2026 | RESEARCH GRANT |
| ICAHN SCHOOL OF MEDICINE | NEW YORK, NY | $12,240 | 2026 | RESEARCH GRANT |
| WEILL MEDICAL COLLEGE OF CORNELL | NEW YORK, NY | $11,444 | 2026 | RESEARCH GRANT |
| BAYLOR COLLEGE OF MEDICINE | HOUSTON, TX | $8,080 | 2026 | RESEARCH GRANT |
| UNIVERSITY OF FLORIDA | GAINESVILLE, FL | $7,853 | 2026 | RESEARCH GRANTS |
| SANFORD BURNHAM PREBYS MEDICAL | LA JOLLA, CA | $7,426 | 2026 | RESEARCH GRANTS |
| PURDUE UNIVERSITY | WEST LAFAYETTE, IN | $5,454 | 2026 | RESEARCH GRANTS |
| UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $1,629,755 | 2025 | RESEARCH GRANT |
| UNIVERSITY OF CALIFORNIA | SAN FRANCISCO, CA | $1,047,540 | 2025 | RESEARCH GRANT |
| DANA-FARBER CANCER INSTITUTE INC | BOSTON, MA | $601,500 | 2025 | RESEARCH GRANT |
| DUKE UNIVERSITY | DURHAM, NC | $382,900 | 2025 | RESEARCH GRANT |
| MASSACHUSETTS INSTITUTE OF TECHNOLO | CAMBRIDGE, MA | $382,560 | 2025 | RESEARCH GRANT |
| METHODIST HOSPITAL RESEARCH INSTITU | HOUSTON, TX | $366,690 | 2025 | RESEARCH GRANT |
| MD ANDERSON CANCER | HOUSTON, TX | $289,425 | 2025 | RESEARCH GRANT |
| COLUMBIA UNIVERSITY | NEW YORK, NY | $287,650 | 2025 | RESEARCH GRANT |
| BROAD INSTITUTE | CAMBRIDGE, MA | $270,560 | 2025 | RESEARCH GRANT |
| SEATTLE CHILDREN'S HOSPITAL | SEATTLE, WA | $255,058 | 2025 | RESEARCH GRANT |
| WASHINGTON UNIVERSITY | ST LOUIS, MO | $233,890 | 2025 | RESEARCH GRANT |
| UNIVERSITY OF MINNESOTA | MINNEAPOLIS, MN | $176,260 | 2025 | RESEARCH GRANT |
| PRESIDENT & FELLOWS OF HARVARD COL | CAMBRIDGE, MA | $150,510 | 2025 | RESEARCH GRANT |
| UNIVERSITY OF VERMONT & STATE AGRI | BURLINGTON, VT | $121,104 | 2025 | RESEARCH GRANT |
| LUCILE PACKARD CHILDREN'S HOSPITAL AT STANFORD | PALO ALTO, CA | $29,578 | 2025 | RESEARCH GRANTS |
| STANFORD UNIVERSITY | STANFORD, CA | $13,512 | 2025 | RESEARCH GRANTS |
| CINCINNATI CHILDREN'S | CINCINNATI, OH | $12,683 | 2025 | RESEARCH GRANT |
| ICAHN SCHOOL OF MEDICINE | NEW YORK, NY | $12,240 | 2025 | RESEARCH GRANT |
| WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY | NEW YORK, NY | $11,444 | 2025 | RESEARCH GRANT |
| BAYLOR COLLEGE OF MEDICINE | HOUSTON, TX | $8,080 | 2025 | RESEARCH GRANT |
| UNIVERSITY OF FLORIDA | GAINESVILLE, FL | $7,853 | 2025 | RESEARCH GRANTS |
| SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE | LA JOLLA, CA | $7,426 | 2025 | RESEARCH GRANTS |
| PURDUE UNIVERSITY | WEST LAFAYETTE, IN | $5,454 | 2025 | RESEARCH GRANTS |
| UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $588,997 | 2024 | PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG |
| DANA-FARBER CANCER INSTITUTE INC | BOSTON, MA | $385,696 | 2024 | PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG |
| LUCILE PACKARD FOUNDATION FOR CHILDREN'S HEALTH | PALO ALTO, CA | $334,500 | 2024 | PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG |
| THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | STANFORD, CA | $327,750 | 2024 | PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG |
UNIVERSITY OF MICHIGAN
$1,629,755RESEARCH GRANT
UNIVERSITY OF CALIFORNIA
$1,047,540RESEARCH GRANT
METHODIST HOSPITAL RESEARCH INSTITU
RESEARCH GRANT
MD ANDERSON CANCER
$289,425RESEARCH GRANT
UNIVERSITY OF MINNESOTA
$176,260RESEARCH GRANT
UNIVERSITY OF VERMONT & STATE AGRI
$121,104RESEARCH GRANT
WEILL MEDICAL COLLEGE OF CORNELL
$11,444RESEARCH GRANT
UNIVERSITY OF FLORIDA
$7,853RESEARCH GRANTS
SANFORD BURNHAM PREBYS MEDICAL
$7,426RESEARCH GRANTS
PURDUE UNIVERSITY
$5,454RESEARCH GRANTS
UNIVERSITY OF MICHIGAN
$1,629,755RESEARCH GRANT
UNIVERSITY OF CALIFORNIA
$1,047,540RESEARCH GRANT
METHODIST HOSPITAL RESEARCH INSTITU
$366,690RESEARCH GRANT
MD ANDERSON CANCER
$289,425RESEARCH GRANT
UNIVERSITY OF MINNESOTA
$176,260RESEARCH GRANT
UNIVERSITY OF VERMONT & STATE AGRI
$121,104RESEARCH GRANT
WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY
$11,444RESEARCH GRANT
UNIVERSITY OF FLORIDA
$7,853RESEARCH GRANTS
SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
$7,426RESEARCH GRANTS
PURDUE UNIVERSITY
$5,454RESEARCH GRANTS
UNIVERSITY OF MICHIGAN
$588,997PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
DANA-FARBER CANCER INSTITUTE INC
$385,696PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG
PEDIATRIC BRAIN CANCER RESEARCH SPECIFIC TO DIPG