Our mission is to generate new knowledge and translate advancements in the prevention, diagnosis, and treatment of diseases that affect children's health through adolescence and adulthood.
A three-year $9 million commitment to advanced therapeutics is one of the clearest signals in the grantmaking of Ann & Robert H Lurie Children's Hospital of Chicago. Through the Children's Research Fund, the foundation backs cellular and genetic therapies at the Stanley Manne Children's Research Institute, alongside seed funding, pilot and bridge grants, and endowed research programs that support pediatric biomedical research. Its giving is also closely tied to the hospital's own research and clinical enterprise, with large mission-support and released-from-restriction grants flowing to affiliated entities such as Pediatric Faculty Foundation Inc, Stanley Manne Children's Research Inst, and Lurie Children's Medical Group LLC. The grant record shows a funder focused on translating research into treatment, especially in areas such as genetics, clinical trials, and pediatric disease research. Community-health investments appear as well through the Patrick M. Magoon Institute / Community Health Implementation Strategy, which guides partnerships in Chicago neighborhoods. The pattern is institution-centered, research-driven, and heavily connected to the hospital's own programs and affiliates.
Research infrastructure is a recurring theme. The Children's Research Fund supports infrastructure and equipment grants for acquisitions such as the INTRABEAM Photon Radiosurgery System, linking philanthropy to the tools needed for pediatric research and care. It also established a $2 million endowment for the Human and Molecular Genetics Research Program, aimed at translational genetic medicine. Clinical research is another clear lane: the fund supports the Clinical and Translational Research program at the Stanley Manne Children's Research Institute, enabling participation in clinical studies and trials. Community health appears through the Patrick M. Magoon Institute / Community Health Implementation Strategy, which directs investments toward equitable care, educational and economic opportunity, safe and nurturing spaces, care coordination, and violence prevention across Chicago communities. Across these areas, the emphasis stays on program-building and institutional capacity rather than stand-alone project philanthropy.
Typical grants are wide-ranging in size, with p25 at $82,055, a median of $1,204,613, and p75 at $6,880,841. The recent record includes both very large mission-support awards and smaller bridge or infrastructure grants, indicating a mix of operating support, released-from-restriction funding, and targeted research backing. Recipients recur across years, especially within the hospital's affiliated research and clinical entities, which points to sustained institutional support rather than one-time awards. The foundation is a Regular Funder and does not fund individuals. Several active programs accept unsolicited requests, including the Children's Research Fund seed/pilot/bridge grants and infrastructure grants, while the clinical and translational research program is listed as not accepting unsolicited requests.
$511M
$3.6B
$1.5B
$1.5B
Most grants fall between $82K and $6.9M, with a median of $1.2M.
25th Percentile
$82K
Median
$1.2M
75th Percentile
$6.9M
About 97% of grants go to recipients in IL.
Thomas P Shanley MD
Ex-Officio Director/President & CEO LCH
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Grantmaking is highly local: 97% of grants go to recipients in Illinois, and the recipient country distribution is entirely US-based. Chicago dominates the map, with many awards landing at Chicago recipients such as Pediatric Faculty Foundation Inc, Stanley Manne Children's Research Inst, and Lurie Children's Surgical Foundation Inc. Outside Chicago, the recent-grants list also includes Almost Home Kids in Naperville, showing that the foundation's reach extends to nearby Illinois locations rather than beyond the region.
The foundation supports pediatric health research, clinical trials, population health, biostatistics and bioinformatics, cancer biology, neurobiology, and mental health. Its active programs also show a strong emphasis on genetics, translational research, research infrastructure, and community health in Chicago.
The grant-size distribution is broad. The 25th percentile is $82,055, the median is $1,204,613, and the 75th percentile is $6,880,841. That mix suggests a combination of smaller seed or infrastructure grants and much larger institutional awards.
Yes. The recent record shows repeated awards to affiliated Chicago organizations across 2023, 2024, and 2025, including Pediatric Faculty Foundation Inc, Stanley Manne Children's Research Inst, and Lurie Children's Surgical Foundation Inc. That pattern indicates ongoing institutional support rather than isolated gifts.
Some programs accept unsolicited requests. The Children's Research Fund seed/pilot/bridge grants accept unsolicited applications, and the infrastructure and equipment grants do as well. The clinical and translational research program is listed as not accepting unsolicited requests.
Giving is overwhelmingly local and concentrated in Illinois. The data show 97% of grants to recipients in the HQ state of Illinois, and the recipient country distribution is 100% US.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| Pediatric Faculty Foundation Inc | CHICAGO, IL | $56,161,772 | 2025 | Mission Support |
| Stanley Manne Children's Research Inst | CHICAGO, IL | $48,015,081 | 2025 | Released from Restriction |
| Lurie Children's Surgical Foundation Inc | CHICAGO, IL | $27,339,350 | 2025 | Mission Support |
| Stanley Manne Children's Research Inst | CHICAGO, IL | $14,111,763 | 2025 | Mission Support |
| Lurie Childrens Pediatric Anesthesia Asc | CHICAGO, IL | $8,186,602 | 2025 | Mission Support |
| Lurie Children's Medical Group LLC | CHICAGO, IL | $7,291,067 | 2025 | Mission Support |
| Lurie Children's Primary Care LLC | CHICAGO, IL | $5,622,930 | 2025 | Mission Support |
| Pediatric Faculty Foundation Inc | CHICAGO, IL | $4,052,527 | 2025 | Released from Restriction |
| Almost Home Kids | CHICAGO, IL | $3,611,931 | 2025 | Mission Support |
| Lurie Children's Health Services LLC | CHICAGO, IL | $3,447,305 | 2025 | Mission Support |
| Childrens Hospital of Chicago Med Ctr | CHICAGO, IL | $2,114,421 | 2025 | Mission Support |
| Lurie Children's Medical Group LLC | CHICAGO, IL | $1,285,806 | 2025 | Released from Restriction |
| Lurie Children's Surgical Foundation Inc | CHICAGO, IL | $782,348 | 2025 | Released from Restriction |
| Lurie Children's Health Services LLC | CHICAGO, IL | $309,930 | 2025 | Released from Restriction |
| AMERICAN HEART ASSOCIATION INC | DALLAS, TX | $104,167 | 2025 | Mission Support |
| Almost Home Kids | CHICAGO, IL | $65,557 | 2025 | Released from Restriction |
| Lurie Children's Pediatric Anesthesia Associates | CHICAGO, IL | $36,327 | 2025 | Released from Restriction |
| LEADERSHIP GREATER CHICAGO INC | CHICAGO, IL | $25,000 | 2025 | Mission Support |
| CHILDREN'S HEART FOUNDATION | NOTHBROOK, IL | $25,000 | 2025 | Mission Support |
| THE MAGNIFICIENT MILE ASSOCIATION | CHICAGO, IL | $18,500 | 2025 | Mission Support |
| ADMIN AWARDS LLC | GARLAND, TX | $17,200 | 2025 | Mission Support |
| RONALD MC DONALD HOUSE | OAK BROOK, IL | $15,000 | 2025 | Mission Support |
| THE CIVIC FEDERATION | CHICAGO, IL | $7,000 | 2025 | Mission Support |
| CITIZENS UNITED FOR RESEARCH IN EPILEPSY | CHICAGO, IL | $6,000 | 2025 | Mission Support |
| YWCA OF METROPOLITAN CHICAGO | CHICAGO, IL | $5,000 | 2025 | Mission Support |
| CHICAGO YOUTH PROGRAMS INC | CHICAGO, IL | $5,000 | 2025 | Mission Support |
| CHICAGO DEFENDER CHARITIES INC | CHICAGO, IL | $5,000 | 2025 | Mission Support |
| AUSTIN COMING TOGETHER | CHICAGO, IL | $5,000 | 2025 | Mission Support |
| PEDIATRIC FACULTY FOUNDATION INC | CHICAGO, IL | $61,016,891 | 2024 | MISSION SUPPORT |
| STANLEY MANNE CHILDREN'S RESEARCH INST | CHICAGO, IL | $43,449,547 | 2024 | RELEASED FROM RESTRICTION |
| LURIE CHILDREN'S SURGICAL FOUNDATION INC | CHICAGO, IL | $37,247,393 | 2024 | MISSION SUPPORT |
| STANLEY MANNE CHILDREN'S RESEARCH INST | CHICAGO, IL | $11,756,422 | 2024 | MISSION SUPPORT |
| LURIE CHILDREN'S PEDIATRIC ANESTHESIA | CHICAGO, IL | $10,879,497 | 2024 | MISSION SUPPORT |
| LURIE CHILDRENS HEALTH SERVICES LLC | CHICAGO, IL | $7,641,898 | 2024 | MISSION SUPPORT |
| PEDIATRIC FACULTY FOUNDATION INC | CHICAGO, IL | $3,823,015 | 2024 | RELEASED FROM RESTRICTION |
| ALMOST HOME KIDS | NAPERVILLE, IL | $2,989,408 | 2024 | MISSION SUPPORT |
| LURIE CHILDREN'S MEDICAL GROUP LLC | CHICAGO, IL | $1,856,994 | 2024 | RELEASED FROM RESTRICTION |
| CHILDRENS HOSPITAL OF CHICAGO MED CTR | CHICAGO, IL | $1,030,299 | 2024 | MISSION SUPPORT |
| LURIE CHILDREN'S SURGICAL FOUNDATION INC | CHICAGO, IL | $713,025 | 2024 | RELEASED FROM RESTRICTION |
| FACULTY PRACTICE PLAN INC | CHICAGO, IL | $494,844 | 2024 | MISSION SUPPORT |
| FACULTY PRACTICE PLAN INC | CHICAGO, IL | $440,233 | 2024 | RELEASED FROM RESTRICTION |
| LURIE CHILDREN'S PRIMARY CARE LLC | CHICAGO, IL | $336,236 | 2024 | RELEASED FROM RESTRICTION |
| LURIE CHILDRENS HEALTH SERVICES LLC | CHICAGO, IL | $309,930 | 2024 | RELEASED FROM RESTRICTION |
| ALMOST HOME KIDS | NAPERVILLE, IL | $100,352 | 2024 | RELEASED FROM RESTRICTION |
| AMERICAN CANCER SOCIETY INC | CHICAGO, IL | $20,000 | 2024 | MISSION SUPPORT |
| LURIE CHILDREN'S PEDIATRIC ANESTHESIA | CHICAGO, IL | $17,991 | 2024 | RELEASED FROM RESTRICTION |
| Lurie Children's Medical Group LLC | CHICAGO, IL | $44,050,805 | 2023 | MISSION SUPPORT |
| Stanley Manne Children's Research Inst | CHICAGO, IL | $32,904,436 | 2023 | RELEASED FROM RESTRICTION |
| Lurie Children's Surgical Foundation Inc | CHICAGO, IL | $24,482,051 | 2023 | MISSION SUPPORT |
| Pediatric Faculty Foundation Inc | CHICAGO, IL | $14,538,904 | 2023 | MISSION SUPPORT |
Pediatric Faculty Foundation Inc
$56,161,772Mission Support
Stanley Manne Children's Research Inst
$48,015,081Released from Restriction
Lurie Children's Surgical Foundation Inc
$27,339,350Mission Support
Stanley Manne Children's Research Inst
$14,111,763Mission Support
Lurie Childrens Pediatric Anesthesia Asc
$8,186,602Mission Support
Lurie Children's Medical Group LLC
$7,291,067Mission Support
Lurie Children's Primary Care LLC
$5,622,930Mission Support
Pediatric Faculty Foundation Inc
$4,052,527Released from Restriction
Almost Home Kids
$3,611,931Mission Support
Lurie Children's Health Services LLC
$3,447,305Mission Support
Childrens Hospital of Chicago Med Ctr
$2,114,421Mission Support
Lurie Children's Medical Group LLC
$1,285,806Released from Restriction
Lurie Children's Surgical Foundation Inc
$782,348Released from Restriction
Lurie Children's Health Services LLC
$309,930Released from Restriction
AMERICAN HEART ASSOCIATION INC
$104,167Mission Support
Almost Home Kids
$65,557Released from Restriction
Lurie Children's Pediatric Anesthesia Associates
$36,327Released from Restriction
LEADERSHIP GREATER CHICAGO INC
$25,000Mission Support
CHILDREN'S HEART FOUNDATION
$25,000Mission Support
THE MAGNIFICIENT MILE ASSOCIATION
$18,500Mission Support
ADMIN AWARDS LLC
$17,200Mission Support
RONALD MC DONALD HOUSE
$15,000Mission Support
THE CIVIC FEDERATION
$7,000Mission Support
CITIZENS UNITED FOR RESEARCH IN EPILEPSY
$6,000Mission Support
YWCA OF METROPOLITAN CHICAGO
$5,000Mission Support
CHICAGO YOUTH PROGRAMS INC
$5,000Mission Support
CHICAGO DEFENDER CHARITIES INC
$5,000Mission Support
AUSTIN COMING TOGETHER
$5,000Mission Support
PEDIATRIC FACULTY FOUNDATION INC
$61,016,891MISSION SUPPORT
STANLEY MANNE CHILDREN'S RESEARCH INST
$43,449,547RELEASED FROM RESTRICTION
LURIE CHILDREN'S SURGICAL FOUNDATION INC
$37,247,393MISSION SUPPORT
STANLEY MANNE CHILDREN'S RESEARCH INST
$11,756,422MISSION SUPPORT
LURIE CHILDREN'S PEDIATRIC ANESTHESIA
$10,879,497MISSION SUPPORT
LURIE CHILDRENS HEALTH SERVICES LLC
$7,641,898MISSION SUPPORT
PEDIATRIC FACULTY FOUNDATION INC
$3,823,015RELEASED FROM RESTRICTION
ALMOST HOME KIDS
$2,989,408MISSION SUPPORT
LURIE CHILDREN'S MEDICAL GROUP LLC
$1,856,994RELEASED FROM RESTRICTION
CHILDRENS HOSPITAL OF CHICAGO MED CTR
$1,030,299MISSION SUPPORT
LURIE CHILDREN'S SURGICAL FOUNDATION INC
$713,025RELEASED FROM RESTRICTION
FACULTY PRACTICE PLAN INC
$494,844MISSION SUPPORT
FACULTY PRACTICE PLAN INC
$440,233RELEASED FROM RESTRICTION
LURIE CHILDREN'S PRIMARY CARE LLC
$336,236RELEASED FROM RESTRICTION
LURIE CHILDRENS HEALTH SERVICES LLC
$309,930RELEASED FROM RESTRICTION
ALMOST HOME KIDS
$100,352RELEASED FROM RESTRICTION
AMERICAN CANCER SOCIETY INC
$20,000MISSION SUPPORT
LURIE CHILDREN'S PEDIATRIC ANESTHESIA
$17,991RELEASED FROM RESTRICTION
Lurie Children's Medical Group LLC
$44,050,805MISSION SUPPORT
Stanley Manne Children's Research Inst
$32,904,436RELEASED FROM RESTRICTION
Lurie Children's Surgical Foundation Inc
$24,482,051MISSION SUPPORT
Pediatric Faculty Foundation Inc
$14,538,904MISSION SUPPORT