The Six Four Foundation concentrates its giving on large, unrestricted gifts to health-related organizations with both an international and local focus. Major support goes to a long-standing Christian medical institution in India and to disease-specific research in the U.S., with an additional significant gift to local disaster/humanitarian response. Grants are made as sizable program support rather than narrowly restricted project funding.
Concentrated, high-dollar giving: a small number of large, unrestricted grants with repeat support to a few core health-focused grantees (both international institution and U.S. disease research), plus targeted local humanitarian support.
The Six Four Foundation’s largest recent grants show a clear preference for unrestricted program support at significant scale, including $5,945,000 to Vellore Christian Medical College Foundation and $3,200,000 to Prostate Cancer Foundation in 2025. That pattern continues across prior years with repeat support for both organizations, suggesting a relationship-based approach rather than one-off project funding. The foundation also made a $1,000,000 unrestricted grant to American Red Cross - North Texas Region in 2025, adding a local disaster-response component to its otherwise health-centered portfolio. Across the recent grants list, the foundation supports medical education, disease research, humanitarian relief, and select education and community-serving organizations. Several recipients appear multiple times over consecutive years, including Vellore Christian Medical College Foundation, Prostate Cancer Foundation, Indiaspora, Dana-farber Cancer Institute, and American India Foundation. Its grantmaking includes both very large awards and smaller six-figure and five-figure grants, but the common thread is flexibility: the grants are labeled as unrestricted program grants throughout the recent record. The result is a portfolio that blends international medical support with U.S.-based health research and targeted community philanthropy.
Health is the foundation’s clearest theme. It gave $3,200,000 to Prostate Cancer Foundation in 2025 and $1,450,000 in 2024, both as unrestricted program grants, alongside $200,000 to Dana-farber Cancer Institute in 2025. Those grants point to a sustained interest in disease research and advocacy. International medical education and hospital support is another recurring area. The foundation granted $5,945,000 to Vellore Christian Medical College Foundation in 2025 and $2,400,000 in 2023, both unrestricted, indicating ongoing support for the institution. It also funds humanitarian and community response. American Red Cross - North Texas Region received $1,000,000 in 2025 for unrestricted program support. Smaller grants also reach education and community organizations such as Thrive Scholars, St Johns University, and Connecting Point of Park Cities.
Typical grant size is $10,000 at the 25th percentile, $25,000 at the median, and $200,000 at the 75th percentile, but the recent record includes several multimillion-dollar awards. The foundation gives repeatedly to the same organizations across multiple years rather than relying only on one-time gifts: Vellore Christian Medical College Foundation, Prostate Cancer Foundation, Indiaspora, Dana-farber Cancer Institute, American India Foundation, Operation Healing Forces, Mt Carmel Educational Foundation, and Connecting Point of Park Cities all appear more than once. The foundation is a private grantmaker, does not fund individuals, and does not make program-related investments. Available recent grants are consistently labeled unrestricted program grants, which suggests flexible operating-style support rather than tightly restricted project funding.
$11.9M
$10.2M
$16.6M
$11.9M
Most grants fall between $10K and $200K, with a median of $25K.
25th Percentile
$10K
Median
$25K
75th Percentile
$200K
About 10% of grants go to recipients in CA.
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Notable grantees: Vellore Christian Medical College Foundation / Vellore Christian Medical College Foundation Inc., Prostate Cancer Foundation, American Red Cross - North Texas Region
Although headquartered in Lewisville, Texas, the foundation’s giving is national and all recent grants in the provided list go to U.S.-based recipients. Texas is the top state by grant count, with 10% of grants going to recipients in the state. Recent Texas recipients include American Red Cross - North Texas Region and Connecting Point of Park Cities in Dallas. Other repeated recipient hubs include New York, Boston, Santa Monica, San Francisco, and Chicago.
Recent grants show support for Christian medical education and hospital work, prostate cancer research and advocacy, local disaster and humanitarian response in North Texas, and some education and community organizations. Recurring recipients include Vellore Christian Medical College Foundation, Prostate Cancer Foundation, American Red Cross - North Texas Region, and Thrive Scholars.
Yes. Every recent grant listed is labeled as an unrestricted program grant, including major awards such as $5,945,000 to Vellore Christian Medical College Foundation, $3,200,000 to Prostate Cancer Foundation, and $1,000,000 to American Red Cross - North Texas Region.
The foundation’s grant-size distribution is $10,000 at the 25th percentile, $25,000 at the median, and $200,000 at the 75th percentile. The recent record also includes much larger awards in the millions, indicating a wide range within a generally flexible grantmaking pattern.
Yes. Several recipients appear across multiple years, including Vellore Christian Medical College Foundation, Prostate Cancer Foundation, Indiaspora, Dana-farber Cancer Institute, American India Foundation, Operation Healing Forces, Mt Carmel Educational Foundation, and Connecting Point of Park Cities.
The foundation gives nationally, but Texas is its top state by grant count. The recent list also shows recipient hubs in New York, California, Massachusetts, Illinois, and Florida, with Texas recipients including American Red Cross - North Texas Region in Dallas and Connecting Point of Park Cities in Dallas.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| VELLORE CHRISTIAN MEDICAL COLLEGE FOUNDATION | NEW YORK, NY | $5,945,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| PROSTATE CANCER FOUNDATION | SANTA MONICA, CA | $3,200,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN RED CROSS - NORTH TEXAS REGION | DALLAS, TX | $1,000,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| THRIVE SCHOLARS | BOSTON, MA | $750,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| INDIASPORA | SAN FRANCISCO, CA | $333,333 | 2025 | UNRESTRICTED PROGRAM GRANT |
| DANA-FARBER CANCER INSTITUTE | BOSTON, MA | $200,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| OPERATION HEALING FORCES | TAMPA, FL | $100,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| MT CARMEL EDUCATIONAL FOUNDATION | CHICAGO, IL | $100,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN INDIA FOUNDATION | NEW YORK, NY | $100,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| ST BALDRICK'S FOUNDATION | MONROVIA, CA | $50,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| CONNECTING POINT OF PARK CITIES | DALLAS, TX | $25,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| NOMI NETWORK | LOS ANGELES, CA | $15,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| CHARITY ADVISORS INC | CHICAGO, IL | $10,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| FARE MEALS | MIAMI BEACH, FL | $10,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| CANADAIAN ASSOCIATION OF NEW YORK FOUNDATION INC | NEW YORK, NY | $10,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN ENTERPRISE INSTITUTE | WASHINGTON, DC | $5,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| LEUKEMIA AND LYMPHOMA SOCIETY | PORT CHESTER, NY | $1,000 | 2025 | UNRESTRICTED PROGRAM GRANT |
| PROSTATE CANCER FOUNDATION | SANTA MONICA, CA | $1,450,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| THRIVE SCHOLARS | BOSTON, MA | $500,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| INDIASPORA | SAN FRANCISCO, CA | $333,333 | 2024 | UNRESTRICTED PROGRAM GRANT |
| OPERATION HEALING FORCES | TAMPA, FL | $100,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| MT CARMEL EDUCATIONAL FOUNDATION | CHICAGO, IL | $100,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN INDIA FOUNDATION | NEW YORK, NY | $100,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| ST JOHNS UNIVERSITY | JAMAICA, NY | $50,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| VIJAY AMRITRAJ FOUNDATION | TARZANA, CA | $25,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| UNIVERSITY OF SOUTHERN CALIFORNIA | LOS ANGELES, CA | $25,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| ST BALDRICKS FOUNDATION | MONROVIA, CA | $25,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| CONNECTING POINT OF PARK CITIES | DALLAS, TX | $25,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| FARE MEALS | MIAMI BEACH, FL | $10,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| CHARITY ADVISORS INC | CHICAGO, IL | $10,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| NOMI NETWORK | NEW YORK, NY | $10,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN ENTERPRISE INSTITUTE | WASHINGTON, DC | $5,000 | 2024 | UNRESTRICTED PROGRAM GRANT |
| VELLORE CHRISTIAN MEDICAL COLLEGE FOUNDATION INC | NEW YORK, NY | $2,400,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| PROSTATE CANCER FOUNDATION | SANTA MONICA, CA | $600,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| INDIASPORA | SAN FRANCISCO, CA | $333,333 | 2023 | UNRESTRICTED PROGRAM GRANT |
| DANA-FARBER CANCER INSTITUTE | BOSTON, MA | $200,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| MT CARMEL EDUCATIONAL FOUNDATION | CHICAGO, IL | $100,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| OPERATION HEALING FORCES | TAMPA, FL | $100,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN INDIA FOUNDATION | NEW YORK, NY | $100,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| MAKE-A-WISH IOWA | URBANDALE, IA | $25,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| CONNECTING POINT OF PARK CITIES | DALLAS, TX | $25,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| ST BALDRICK S FOUNDATION | MONROVIA, CA | $25,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| CHARITY ADVISORS INC | CHICAGO, IL | $10,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| THE UNIVERSITY OF TEXAS FOUNDATION INC | AUSTIN, TX | $10,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| NEW JERSEY BICYCLE COALITION | MONTCLAIR, NJ | $5,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| AMERICAN ENTERPRISE INSTITUTE | WASHINGTON, DC | $5,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| NATIONAL MS SOCIETY | WASHINGTON, DC | $5,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| NOMI NETWORK | LOS ANGELES, CA | $5,000 | 2023 | UNRESTRICTED PROGRAM GRANT |
| INTERNATIONAL RESCUE COMMITTEE | NEW YORK, NY | $300 | 2023 | UNRESTRICTED PROGRAM GRANT |
UNRESTRICTED PROGRAM GRANT
MT CARMEL EDUCATIONAL FOUNDATION
$100,000UNRESTRICTED PROGRAM GRANT
NOMI NETWORK
$15,000UNRESTRICTED PROGRAM GRANT
CHARITY ADVISORS INC
$10,000UNRESTRICTED PROGRAM GRANT
FARE MEALS
$10,000UNRESTRICTED PROGRAM GRANT
CANADAIAN ASSOCIATION OF NEW YORK FOUNDATION INC
$10,000UNRESTRICTED PROGRAM GRANT
LEUKEMIA AND LYMPHOMA SOCIETY
$1,000UNRESTRICTED PROGRAM GRANT
MT CARMEL EDUCATIONAL FOUNDATION
$100,000UNRESTRICTED PROGRAM GRANT
ST JOHNS UNIVERSITY
$50,000UNRESTRICTED PROGRAM GRANT
VIJAY AMRITRAJ FOUNDATION
$25,000UNRESTRICTED PROGRAM GRANT
FARE MEALS
$10,000UNRESTRICTED PROGRAM GRANT
CHARITY ADVISORS INC
$10,000UNRESTRICTED PROGRAM GRANT
NOMI NETWORK
$10,000UNRESTRICTED PROGRAM GRANT
UNRESTRICTED PROGRAM GRANT
MT CARMEL EDUCATIONAL FOUNDATION
$100,000UNRESTRICTED PROGRAM GRANT
CHARITY ADVISORS INC
$10,000UNRESTRICTED PROGRAM GRANT
NEW JERSEY BICYCLE COALITION
$5,000UNRESTRICTED PROGRAM GRANT
NOMI NETWORK
$5,000UNRESTRICTED PROGRAM GRANT