Making 90 the new 50 by 2030 — accelerate research and development to extend healthy human lifespan and regenerative medicine.
The Methuselah Foundation backs research intended to extend healthy human lifespan, with a strong emphasis on regenerative medicine, aging, and translational biomedical work. In the recent grants list, one of its largest commitments went to Ichor Research Institute Inc in La Fayette, New York, including a $4,289,336 award in 2024 and a separate $1,800,000 grant that same year. Another major recipient was Albert Einstein College of Medicine in the Bronx, New York, which received $1,050,000 for research. The foundation also funded the Buck Institute for Research on Aging, the Alliance for Longevity Initiatives, and Healthspan Action Coalition, showing a mix of laboratory research, advocacy, and field-building support. Its portfolio also includes programmatic challenge funding, including the NASA / Methuselah Vascular Tissue Challenge, which focuses on creating vascularized human tissue for regenerative applications. Across the grants shown, the foundation supports clinical researchers, academic medical centers, clinical research teams, and research organizations working on longevity-related science.
In aging and longevity research, the foundation made multiple grants tied to specific research programs, including $500,000 to Ichor Life Sciences Inc in La Fayette, New York, and $650,000 to the Buck Institute for Research on Aging in Novato, California. It also supported the translational side of the field through $250,000 to The Center for the Advancement of Science in Space Inc in Melbourne, Florida. On the policy and field-building side, The Methuselah Foundation gave $445,000 to The Alliance for Longevity Initiatives in Washington, DC, and $400,000 to Lifespan Extension Advocacy Foundation Inc in Seaford, New York. The grant list also includes support for medical and clinical research, such as $100,000 to Everest Health Partners LLC in Alexandria, Virginia, for clinical research.
The typical grant size is $39,584 at the 25th percentile, $150,000 at the median, and $422,500 at the 75th percentile. The recent list shows both very large research awards and smaller follow-on grants, including repeated funding to the same recipient across multiple entries and years, such as Ichor Research Institute Inc and Everest Health Partners LLC. The foundation makes program-related investments and also uses competitive challenge funding through the NASA / Methuselah Vascular Tissue Challenge, which accepts unsolicited entries. The pattern suggests project-specific research funding rather than open-ended institutional support.
$379K
$20.4M
$2M
$2.6M
Most grants fall between $40K and $423K, with a median of $150K.
25th Percentile
$40K
Median
$150K
75th Percentile
$423K
About 7% of grants go to recipients in CA.
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Grant recipients are entirely U.S.-based in the recent list, with New York as the top state by grant count. The largest concentrations include La Fayette and Bronx, New York, along with recurring activity in Wellington, Florida; Washington, DC; and California cities such as Novato, Sunnyvale, Los Gatos, Santa Clara, and Seattle. Recipient locations also include Alexandria, Virginia, and Boston, Massachusetts. No grants in the sample went to recipients in Virginia, the foundation’s headquarters state.
The foundation funds aging, longevity, healthspan, regenerative medicine, biomedical research, and prize competitions or challenges. In the recent grants list, that includes research awards to academic and research institutions, as well as field-building support and clinical research funding.
Yes. It runs the NASA / Methuselah Vascular Tissue Challenge, a competitive program for producing vascularized human tissue. The challenge offers cash prizes and includes funding for the first-place team.
The typical grant size is $39,584 at the 25th percentile, $150,000 at the median, and $422,500 at the 75th percentile. The recent grants include both six-figure awards and smaller research and operations grants.
New York is the top state by grant count in the recent data. Recipient cities there include La Fayette, Bronx, and Seaford, which appear multiple times across the grant list.
No. The recent recipient distribution shows 0% of grants to recipients in Virginia, while all listed grants in the sample went to U.S.-based organizations.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| EVEREST HEALTH PARTNERS LLC | ALEXANDRIA, VA | $100,000 | 2025 | CLINICAL RESEARCH |
| LESS DEATH INC | SANTA CLARA, CA | $100,000 | 2025 | OPERATIONS GRANT |
| EVEREST HEALTH PARTNERS LLC | ALEXANDRIA, VA | $60,000 | 2025 | CLINICAL RESEARCH |
| AMARANTH LLC | DALLAS, TX | $50,000 | 2025 | RESEARCH GRANT |
| OISIN BIOTECHNOLOGIES INC | SEATTLE, WA | $40,000 | 2025 | RESEARCH GRANT |
| PARVO MEDICS INC | SALT LAKE CITY, UT | $16,237 | 2025 | MEDICAL RESEARCH |
| THE BRIGHAM & WOMENS HOSPITAL INC | BOSTON, MA | $13,000 | 2025 | MEDICAL RESEARCH |
| Ichor Research Institute Inc | La Fayette, NY | $4,289,336 | 2024 | Research |
| Ichor Research Institute INC | La Fayette, NY | $1,800,000 | 2024 | Research |
| Albert Einstein College of Medicine | Bronx, NY | $1,050,000 | 2024 | Research |
| Buck Institute for Research on Aging | Novato, CA | $650,000 | 2024 | Research |
| Ichor Life Sciences Inc | La Fayette, NY | $500,000 | 2024 | Research |
| The Alliance for Longevity Initiatives | Washington, DC | $445,000 | 2024 | Research |
| Actual Food | New Haven, CT | $400,000 | 2024 | — |
| Lifespan Extension Advocacy Foundation Inc | Seaford, NY | $400,000 | 2024 | Research |
| ADG Lilico LLC | Sunnyvale, CA | $375,000 | 2024 | Research |
| The Center for the Advancement of Science in Space Inc | Melbourne, FL | $250,000 | 2024 | Research |
| 21st Century Medicine Inc | Fontana, CA | $250,000 | 2024 | Research |
| Healthspan Action Coalition Inc | Wellington, FL | $150,000 | 2024 | Research |
| ADG LiliCo LLC | Los Gatos, CA | $125,000 | 2024 | Research |
| AXOLOTL LLC | Wellington, FL | $100,000 | 2024 | Research |
| The Alliance for Longevity Initiatives | Washington, DC | $80,000 | 2024 | Research |
| Center for Contemporary Sciences | Gaithersburg, MD | $60,000 | 2024 | Research |
| Healthspan Action Coalition Inc | Wellington, FL | $50,000 | 2024 | Research |
| SENS Foundation | Mountain View, CA | $29,167 | 2024 | Research |
| Ora Biomedical Inc | Tukwila, WA | $25,000 | 2024 | Research |
| Center for Contemporary Sciences | GAITHERSBURG, MD | $25,000 | 2024 | Research |
| Moral Injury of Healthcare LLC | Carlisle, PA | $10,000 | 2024 | Research |
| Long Life Labs LLC | Temple Terrace, FL | $9,850 | 2024 | Research |
| Long Life Labs LLC | Temple Terrace, FL | $7,813 | 2024 | Research |
EVEREST HEALTH PARTNERS LLC
$100,000CLINICAL RESEARCH
LESS DEATH INC
$100,000OPERATIONS GRANT
EVEREST HEALTH PARTNERS LLC
$60,000CLINICAL RESEARCH
AMARANTH LLC
$50,000RESEARCH GRANT
OISIN BIOTECHNOLOGIES INC
$40,000RESEARCH GRANT
PARVO MEDICS INC
$16,237MEDICAL RESEARCH
THE BRIGHAM & WOMENS HOSPITAL INC
MEDICAL RESEARCH
Ichor Research Institute Inc
$4,289,336Research
Ichor Research Institute INC
$1,800,000Research
Ichor Life Sciences Inc
$500,000Research
The Alliance for Longevity Initiatives
$445,000Research
Actual Food
$400,000ADG Lilico LLC
$375,000Research
The Center for the Advancement of Science in Space Inc
$250,000Research
21st Century Medicine Inc
$250,000Research
Healthspan Action Coalition Inc
$150,000Research
ADG LiliCo LLC
$125,000Research
AXOLOTL LLC
$100,000Research
The Alliance for Longevity Initiatives
$80,000Research
Center for Contemporary Sciences
$60,000Research
Healthspan Action Coalition Inc
$50,000Research
Ora Biomedical Inc
$25,000Research
Center for Contemporary Sciences
$25,000Research
Moral Injury of Healthcare LLC
$10,000Research
Long Life Labs LLC
$9,850Research
Long Life Labs LLC
$7,813Research