The MacMillan Family Foundation appears to concentrate its philanthropy on high-impact biomedical research, demonstrated by a single large general-purpose grant to the New York Genome Center. The foundation’s giving suggests a preference for supporting research infrastructure and institutional capacity in genomics, likely focused on major, city-based research centers rather than many small local projects.
Highly concentrated: one very large, one-off general-purpose award to a single grantee, indicating preference for major institutional investments rather than many small or diversified grants.
A $5 million general-purpose grant to the New York Genome Center anchored The Macmillan Family Foundation Inc’s latest giving and points to a strong interest in biomedical research infrastructure. The foundation also made a $1.6 million general-purpose grant to Columbia University and a $1.075 million general-purpose grant to the Institute for Advanced Study, showing support for major research institutions rather than project-specific awards. In the same grant cycle, it extended seven-figure general-purpose support to Princeton Healthcare System Foundation, Canadian Institute for Advanced Research, and The Mark Foundation for Cancer Research. Beyond research, the portfolio includes education, health, youth development, arts, and community institutions. Grants to Children’s Hospital of Philadelphia Foundation, Center for Supportive Schools, and Target ALS show a mix of medical and educational priorities, while support for School of American Ballet, Central Park Conservancy, and the Metropolitan Museum of Art indicates continued backing for cultural organizations. The pattern is broad in institutional terms, but the grant purposes remain consistent: general-purpose support for established nonprofits and research bodies.
In biomedical science, the foundation gave $5 million to New York Genome Center Inc for general purpose support and $1 million to The Mark Foundation for Cancer Research for the same purpose, underscoring a preference for large research organizations. It also gave $230,000 to Life Sciences Research Foundation, extending support to the research pipeline. Education and youth-serving work appears as another thread. The foundation awarded $500,000 to Center for Supportive Schools and $250,000 to Partnership With Children, both for general purpose support. It also gave $200,000 to Counseling in Schools and $200,000 to City Year New York. Arts and civic institutions also receive funding. Grants include $325,000 to School of American Ballet, $250,000 to Joyce Theatre Foundation Inc, $200,000 to Metropolitan Museum of Art, and $200,000 to The Apollo Theater Foundation Inc, all listed as general purpose support.
The recent grant list is dominated by large, unrestricted awards: one $5 million grant, several in the $1 million to $1.6 million range, and many additional grants in the $200,000 to $575,000 range. The foundation is a private foundation and a regular funder, not a DAF sponsor. The pattern shown in the file is largely one-time giving in 2025, with grants labeled general purpose rather than tied to a formal application process or project cycle. The recipients are institutional organizations rather than individuals.
$23.3M
$554.9M
$113.8M
$31.3M
Top 2 recipient countries by grant volume for Macmillan Family Foundation.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 371 | $67.1M | 99.5% |
| 2 | Canada |
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Notable grantees: New York Genome Center
Grant recipients are concentrated in the Northeast, especially New York and New Jersey. New York City recipients include New York Genome Center Inc, Columbia University, The Mark Foundation for Cancer Research, School of American Ballet, Central Park Conservancy, and The Apollo Theater Foundation Inc. New Jersey recipients include Institute for Advanced Study in Princeton, Princeton Healthcare System Foundation in Plainsboro, and Center for Supportive Schools in Princeton. Outside the U.S., the only listed recipient country is Canada, with one grant to Canadian Institute for Advanced Research in Toronto.
Its recent grants go mainly to large institutions in research, education, health, arts, and community services. Examples from the list include New York Genome Center Inc, Columbia University, Center for Supportive Schools, Children’s Hospital of Philadelphia Foundation, and Metropolitan Museum of Art, all funded for general purpose support.
The largest recent award is $5 million, and other top grants include $1.6 million, $1.075 million, $1.025 million, and $1 million awards. Many additional grants sit in the $200,000 to $575,000 range, which suggests a preference for sizable institutional support.
The recipient list is overwhelmingly U.S.-based, with 150 grants in the U.S. and 1 in Canada. Within the U.S., many recipients are in New York City and New Jersey, including organizations in New York, Princeton, Plainsboro, Brooklyn, Bronx, and New Brunswick.
Yes. Recent grants include $5 million to New York Genome Center Inc, $1 million to The Mark Foundation for Cancer Research, $1.075 million to the Institute for Advanced Study, and $230,000 to Life Sciences Research Foundation. These awards point to sustained support for biomedical and broader scientific research institutions.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| 2 |
| $2M |
0.5% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| NEW YORK GENOME CENTER INC | NEW YORK, NY | $5,000,000 | 2025 | GENERAL PURPOSE |
| COLUMBIA UNIVERSITY | NEW YORK, NY | $1,600,000 | 2025 | GENERAL PURPOSE |
| INSTITUTE FOR ADVANCED STUDY | PRINCETON, NJ | $1,075,000 | 2025 | GENERAL PURPOSE |
| PRINCETON HEALTHCARE SYSTEM FOUNDATION | PLAINSBORO, NJ | $1,025,000 | 2025 | GENERAL PURPOSE |
| THE MARK FOUNDATION FOR CANCER RESEARCH | NEW YORK, NY | $1,000,000 | 2025 | GENERAL PURPOSE |
| CANADIAN INSTITUTE FOR ADVANCED RESEARCH | TORONTO | $1,000,000 | 2025 | GENERAL PURPOSE |
| CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION | PHILADELPHIA, PA | $575,000 | 2025 | GENERAL PURPOSE |
| CENTER FOR SUPPORTIVE SCHOOLS | PRINCETON, NJ | $500,000 | 2025 | GENERAL PURPOSE |
| FOUNDATION FOR EDUCATIONAL ADMINISTRATION | MONROE TWP, NJ | $337,000 | 2025 | GENERAL PURPOSE |
| CENTRAL PARK CONSERVANCY | NEW YORK, NY | $325,000 | 2025 | GENERAL PURPOSE |
| SCHOOL OF AMERICAN BALLET | NEW YORK, NY | $325,000 | 2025 | GENERAL PURPOSE |
| RUTGERS UNIVERSITY FOUNDATION | NEW BRUNSWICK, NJ | $325,000 | 2025 | GENERAL PURPOSE |
| PRINCETON AREA COMMUNITY FOUNDATION | LAWRENCEVILLE, NJ | $325,000 | 2025 | GENERAL PURPOSE |
| TARGET ALS | NEW YORK, NY | $250,000 | 2025 | GENERAL PURPOSE |
| THE CHILD CENTER OF NY | FOREST HILLS, NY | $250,000 | 2025 | GENERAL PURPOSE |
| JOYCE THEATRE FOUNDATION INC | NEW YORK, NY | $250,000 | 2025 | GENERAL PURPOSE |
| PARTNERSHIP WITH CHILDREN | NEW YORK, NY | $250,000 | 2025 | GENERAL PURPOSE |
| CHILDREN'S AID SOCIETY | NEW YORK, NY | $250,000 | 2025 | GENERAL PURPOSE |
| LIFE SCIENCES RESEARCH FOUNDATION | CHARLOTTE, NC | $230,000 | 2025 | GENERAL PURPOSE |
| EL MUSEO DEL BARRIO | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| GLOBAL KIDS | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| NEW YORK EDGE | WOODSIDE, NY | $200,000 | 2025 | GENERAL PURPOSE |
| PHIPPS NEIGHBORDHOODS INC | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| CENTER FOR FAMILY LIFE IN SUNSET PARK | BROOKLYN, NY | $200,000 | 2025 | GENERAL PURPOSE |
| THE APOLLO THEATER FOUNDATION INC | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| HENRY STREET SETTLEMENT | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| METROPOLITAN MUSEUM OF ART | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| COUNSELING IN SCHOOLS | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| CITY YEAR NEW YORK | NEW YORK, NY | $200,000 | 2025 | GENERAL PURPOSE |
| ST NICKS ALLIANCE | BROOKLYN, NY | $175,000 | 2025 | GENERAL PURPOSE |
| EAST SIDE HOUSE | BRONX, NY | $175,000 | 2025 | GENERAL PURPOSE |
| MAKE THE ROAD NEW YORK | BROOKLYN, NY | $175,000 | 2025 | GENERAL PURPOSE |
| CHINESE AMERICAN PLANNING COUNCIL | NEW YORK, NY | $175,000 | 2025 | GENERAL PURPOSE |
| PRINCETON BALLET SOCIETY | NEW BRUNSWICK, NJ | $170,000 | 2025 | GENERAL PURPOSE |
| BRONXWORKS | BRONX, NY | $150,000 | 2025 | GENERAL PURPOSE |
| SOUTH ASIAN YOUTH ACTION (SAYA) | QUEENS, NY | $150,000 | 2025 | GENERAL PURPOSE |
| NATIONAL BLACK THEATRE | NEW YORK, NY | $150,000 | 2025 | GENERAL PURPOSE |
| GOOD SHEPHERD SERVICES | NEW YORK, NY | $150,000 | 2025 | GENERAL PURPOSE |
| ALL OUR KIN INC | NEW HAVEN, CT | $146,500 | 2025 | GENERAL PURPOSE |
| CYPRESS HILL LOCAL DEVELOPMENT CORPORATION | BROOKLYN, NY | $130,000 | 2025 | GENERAL PURPOSE |
| REPLICATIONS INC | NEW YORK, NY | $128,000 | 2025 | GENERAL PURPOSE |
| YMCA OF GREATER NEW YORK | NEW YORK, NY | $125,000 | 2025 | GENERAL PURPOSE |
| EL PUENTE | BROOKLYN, NY | $125,000 | 2025 | GENERAL PURPOSE |
| SHAKESPEARE THEATRE OF NEW JERSEY | FLORHAM PARK, NJ | $120,000 | 2025 | GENERAL PURPOSE |
| CHILDREN'S FUTURES | TRENTON, NJ | $119,500 | 2025 | GENERAL PURPOSE |
| MUSEUM OF THE CITY OF NEW YORK | NEW YORK, NY | $100,000 | 2025 | GENERAL PURPOSE |
| GROUNDS FOR SCULPTURE | HAMILTON, NJ | $100,000 | 2025 | GENERAL PURPOSE |
| THE EDUCATIONAL ALLIANCE INC | NEW YORK, NY | $100,000 | 2025 | GENERAL PURPOSE |
| REEL WORKS | BROOKLYN, NY | $100,000 | 2025 | GENERAL PURPOSE |
| NEW 42 | NEW YORK, NY | $100,000 | 2025 | GENERAL PURPOSE |
COLUMBIA UNIVERSITY
$1,600,000GENERAL PURPOSE
THE MARK FOUNDATION FOR CANCER RESEARCH
$1,000,000GENERAL PURPOSE
CANADIAN INSTITUTE FOR ADVANCED RESEARCH
GENERAL PURPOSE
FOUNDATION FOR EDUCATIONAL ADMINISTRATION
$337,000GENERAL PURPOSE
PRINCETON AREA COMMUNITY FOUNDATION
$325,000GENERAL PURPOSE
TARGET ALS
$250,000GENERAL PURPOSE
JOYCE THEATRE FOUNDATION INC
$250,000GENERAL PURPOSE
ST NICKS ALLIANCE
$175,000GENERAL PURPOSE
NATIONAL BLACK THEATRE
$150,000GENERAL PURPOSE
CYPRESS HILL LOCAL DEVELOPMENT CORPORATION
$130,000GENERAL PURPOSE
REPLICATIONS INC
$128,000GENERAL PURPOSE
CHILDREN'S FUTURES
$119,500GENERAL PURPOSE
REEL WORKS
$100,000GENERAL PURPOSE
NEW 42
$100,000GENERAL PURPOSE