The Halloran Family Foundation is primarily focused on funding biomedical research into primary sclerosing cholangitis (PSC), making multi-year, large grants to clinical centers and research biobanks both in the U.S. and abroad. Alongside that core disease-focused philanthropy, the foundation gives to a small set of recurring local Minnesota causes — notably college athletics and hunger relief — and also routes funds through a grantmaking intermediary. Grants tend to be targeted and repeatable rather than broadly distributed.
The Halloran Family Foundation Inc has built its giving around primary sclerosing cholangitis, backing research infrastructure, clinical trials, and biobanks across multiple years. Its largest recent awards include a $663,532 grant to Mayo Clinic Rochester for an AI imagining study and PSC research initiative, followed by several large installments to Mayo Clinic Rochester and Oslo University for PSC biobank and clinical-trial work. The pattern is not limited to one institution: the foundation has supported U.S. and international medical centers, including repeated grants to Psc Partners Seeking a Cure and Novartis Institute for Biomedical Research. Alongside the disease-focused portfolio, the foundation also maintains a smaller set of recurring local grants. Those include University of Minnesota Foundation support for wrestling, Constellation Fund installments in Minneapolis, and Minnesota community organizations such as Second Harvest Heartland, The Nature Conservancy, and Twin Cities Public Television Inc. That mix shows a foundation that concentrates on a narrow medical field while also sustaining a few ongoing regional commitments.
A major share of the foundation’s biomedical giving supports PSC research infrastructure. Mayo Clinic Rochester received $489,500 in 2024 for biobank, clinic imaging, and exposomics, and $461,332 in 2025 for PSC biobank and PSC research. Oslo University also received PSC-related support, including $450,205 in 2024 for biobank and clinical trials in PSC. The foundation also backs research talent. Novartis Institute for Biomedical Research received $165,945 in 2025 and $137,806 in 2024 for PhD fellowship support, with an earlier $33,155 grant in 2023 for the same purpose. Beyond biomedical work, the portfolio includes Minnesota-based community and cultural support. Second Harvest Heartland received $204,762 in 2025 for general support, and Twin Cities Public Television Inc received $40,079 in 2023 for The Minnesota Experience.
Typical grant size sits at $5,000 at the 25th percentile, $36,617 at the median, and $215,380 at the 75th percentile, reflecting a mix of small local grants and much larger research awards. The foundation makes repeated grants to the same recipients across multiple years, especially in PSC research and a few Minnesota institutions. It also funds individuals, and it does not make program-related investments. The recurring installments to Constellation Fund indicate multi-year, structured support rather than one-off gifts.
$2M
$37.8M
$6.3M
$2.2M
Most grants fall between $5K and $215K, with a median of $37K.
25th Percentile
$5K
Median
$37K
75th Percentile
$215K
About 10% of grants go to recipients in MN.
Top 3 recipient countries by grant volume for Halloran Family Foundation.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 42 | $4.4M | 84.0% |
| 2 | Switzerland |
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Concentrated, high-dollar support focused on a few repeat grantees (multiple multi-installment grants to the same institutions), with the largest awards directed to PSC research centers and biobanks and smaller but recurring local community grants.
Notable grantees: Mayo Clinic Rochester, Oslo University, PSC Partners Seeking a Cure, University of Minnesota Foundation, Second Harvest Heartland
Grantmaking is national, with 84.0% of grants going to U.S. recipients. Tennessee is the top state by grant count, followed by a substantial cluster in Minnesota and recurring international awards in Switzerland and Norway. Among named recipient cities, Rochester and Minneapolis appear repeatedly, along with Saint Paul, Memphis, Greenwood Village, and Nydalen. The foundation gives 11% of grants to recipients in New York, its headquarters state.
Its core focus is primary sclerosing cholangitis, with grants for PSC biobanks, clinical trials, clinic imaging, exposomics, and related research support. The portfolio also includes a smaller set of Minnesota community grants and research fellowship funding.
Yes. Multiple recipients appear in consecutive years, including Mayo Clinic Rochester, Oslo University, Psc Partners Seeking a Cure, Novartis Institute for Biomedical Research, University of Minnesota Foundation, Constellation Fund, and Twin Cities Public Television Inc.
The typical grant size is $5,000 at the 25th percentile, $36,617 at the median, and $215,380 at the 75th percentile. That spread shows a combination of smaller operating grants and larger research installments.
Outside PSC research, it has supported the University of Minnesota wrestling program, Second Harvest Heartland, The Nature Conservancy, Children's Theatre Company, Twin Cities Public Television Inc, and Ducks Unlimited Inc through grants labeled general support or initiative support.
By grant count, Tennessee is the top state, while Minnesota also receives many grants, especially in Minneapolis and Rochester. International recipients in Nydalen and Basel also appear in the recent grants list.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| 5 |
| $641K |
10.0% |
| 3 | Norway | 3 | $1.2M | 6.0% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| MAYO CLINIC ROCHESTER | ROCHESTER, MN | $461,332 | 2025 | SUPPORT FOR PSC BIOBANK AND PSC RESEARCH |
| OSLO UNIVERSITY | NYDALEN | $352,493 | 2025 | SUPPORT FOR PSC BIOBANK |
| CONSTELLATION FUND | MINNEAPOLIS, MN | $251,605 | 2025 | GRANT PROGRAM (4TH INSTALLMENT) |
| UNIVERSITY OF MINNESOTA FOUNDATION | MINNEAPOLIS, MN | $244,171 | 2025 | WRESTLING SUPPORT |
| SECOND HARVEST HEARTLAND | BROOKLYN PARK, MN | $204,762 | 2025 | GENERAL SUPPORT |
| PSC PARTNERS SEEKING A CURE | GREENWOOD VILLAGE, CO | $200,552 | 2025 | GENERAL SUPPORT |
| NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH | BASEL | $165,945 | 2025 | PHD FELLOWSHIP SUPPORT |
| THE NATURE CONSERVANCY | MINNEAPOLIS, MN | $49,428 | 2025 | GENERAL SUPPORT |
| CHILDREN'S THEATRE COMPANY | MINNEAPOLIS, MN | $49,188 | 2025 | GENERAL SUPPORT |
| TWIN CITIES PUBLIC TELEVISION INC | SAINT PAUL, MN | $39,435 | 2025 | GENERAL SUPPORT |
| DUCKS UNLIMITED INC | MEMPHIS, TN | $24,815 | 2025 | LIVING LAKES INITIATIVE |
| RIDGEVIEW MEDICAL CENTER | WACONIA, MN | $1,020 | 2025 | GENERAL SUPPORT |
| RELEASE RECOVERY FOUNDATION | NEW YORK, NY | $1,000 | 2025 | GENERAL SUPPORT |
| DELTA WATERFOWL FOUNDATION | BISMARCK, ND | $500 | 2025 | GENERAL SUPPORT |
| ANDEAN COMMUNITY PARTNERS | MINNEAPOLIS, MN | $500 | 2025 | GENERAL SUPPORT |
| PSC PARTNERS SEEKING A CURE | GREENWOOD VILLAGE, CO | $200 | 2025 | GENERAL SUPPORT |
| MAYO CLINIC ROCHESTER | ROCHESTER, MN | $489,500 | 2024 | GRANT INSTALLMENTS FOR BIOBANK, CLINIC IMAGING, AND EXPOSOMICS |
| OSLO UNIVERSITY | NYDALEN | $450,205 | 2024 | SUPPORT BIOBANK AND CLINICAL TRIALS IN PSC |
| CONSTELLATION FUND | MINNEAPOLIS, MN | $252,565 | 2024 | GRANT PROGRAM (3RD INSTALLMENT) |
| UNIVERSITY OF MINNESOTA FOUNDATION | MINNEAPOLIS, MN | $251,526 | 2024 | WRESTLING SUPPORT |
| PSC PARTNERS SEEKING A CURE | GREENWOOD VILLAGE, CO | $198,659 | 2024 | GENERAL SUPPORT |
| NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH | BASEL | $137,806 | 2024 | PHD FELLOWSHIP SUPPORT |
| THE NATURE CONSERVANCY | MINNEAPOLIS, MN | $50,335 | 2024 | GENERAL SUPPORT |
| CHILDREN'S THEATRE COMPANY | MINNEAPOLIS, MN | $50,335 | 2024 | GENERAL SUPPORT |
| TWIN CITIES PUBLIC TELEVISION INC | SAINT PAUL, MN | $40,298 | 2024 | GENERAL SUPPORT |
| DUCKS UNLIMITED INC | MEMPHIS, TN | $25,167 | 2024 | LIVING LAKES INITIATIVE |
| FREEDOM FROM RELIGION FOUNDATION | MINNEAPOLIS, MN | $10,127 | 2024 | GENERAL SUPPORT |
| NATIONAL NATIVE AMERICAN BAR ASSOCIATION FOUNDATION | TEMPE, AZ | $10,000 | 2024 | GENERAL SUPPORT |
| CONSTELLATION FUND | MINNEAPOLIS, MN | $10,000 | 2024 | GENERAL SUPPORT |
| THREE RIVERS PAK DISTRICT FOUNDATION INC | PLYMOUTH, MN | $5,000 | 2024 | GENERAL SUPPORT |
| MACPHAIL CENTER FOR MUSIC | MINNEAPOLIS, MN | $5,000 | 2024 | GENERAL SUPPORT |
| RONALD MCDONALD HOUSE CHARITIES INC | CHICAGO, IL | $1,000 | 2024 | GENERAL SUPPORT |
| RELEASE RECOVERY FOUNDATION | NEW YORK, NY | $1,000 | 2024 | GENERAL SUPPORT |
| PSC PARTNERS SEEKING A CURE | GREENWOOD VILLAGE, CO | $1,000 | 2024 | GENERAL SUPPORT |
| MAYO CLINIC ROCHESTER | ROCHESTER, MN | $663,532 | 2023 | AI IMAGINING STUDY & PSC RESEARCH INITIATIVE |
| OSLO UNIVERSITY | NYDALEN | $439,950 | 2023 | SUPPORT BIOBANK INITIATIVE, NOPSC, AND PROJECT 42251 |
| UNIVERSITY OF MINNESOTA FOUNDATION | MINNEAPOLIS, MN | $251,234 | 2023 | WRESTLING PROGRAM SUPPORT |
| CONSTELLATION FUND | MINNEAPOLIS, MN | $250,063 | 2023 | CONSTELLATION'S GRANT PROGRAM |
| PSC PARTNERS SEEKING A CURE | GREENWOOD VILLAGE, CO | $203,819 | 2023 | GENERAL SUPPORT |
| CHILDREN'S THEATRE COMPANY | MINNEAPOLIS, MN | $50,087 | 2023 | GENERAL SUPPORT |
| TWIN CITIES PUBLIC TELEVISION INC | SAINT PAUL, MN | $40,079 | 2023 | GENERAL SUPPORT FOR THE MINNESOTA EXPERIENCE |
| NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH | BASEL | $33,155 | 2023 | PHD FELLOWSHIP SUPPORT |
| DUCKS UNLIMITED INC | MEMPHIS, TN | $25,091 | 2023 | LIVING LAKES INITIATIVE |
| FRIENDS OF NGONG ROAD | MINNEAPOLIS, MN | $15,000 | 2023 | GENERAL SUPPORT |
| RELEASE RECOVERY FOUNDATION | NEW YORK, NY | $1,000 | 2023 | GENERAL SUPPORT |
| MICHAEL J FOX FOUNDATION | NEW YORK, NY | $1,000 | 2023 | GENERAL SUPPORT |
| PINE TREE APPLE CLASSIC FUND | LAKEVILLE, MN | $500 | 2023 | GENERAL SUPPORT |
| DELANO AREA COUNCIL FOR ARTS AND CULTURE | DELANO, MN | $250 | 2023 | GENERAL SUPPORT |
MAYO CLINIC ROCHESTER
$461,332SUPPORT FOR PSC BIOBANK AND PSC RESEARCH
OSLO UNIVERSITY
$352,493SUPPORT FOR PSC BIOBANK
CONSTELLATION FUND
$251,605GRANT PROGRAM (4TH INSTALLMENT)
UNIVERSITY OF MINNESOTA FOUNDATION
$244,171WRESTLING SUPPORT
SECOND HARVEST HEARTLAND
$204,762GENERAL SUPPORT
PSC PARTNERS SEEKING A CURE
$200,552GENERAL SUPPORT
NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH
$165,945PHD FELLOWSHIP SUPPORT
THE NATURE CONSERVANCY
$49,428GENERAL SUPPORT
CHILDREN'S THEATRE COMPANY
$49,188GENERAL SUPPORT
TWIN CITIES PUBLIC TELEVISION INC
$39,435GENERAL SUPPORT
DUCKS UNLIMITED INC
$24,815LIVING LAKES INITIATIVE
RIDGEVIEW MEDICAL CENTER
$1,020GENERAL SUPPORT
RELEASE RECOVERY FOUNDATION
$1,000GENERAL SUPPORT
DELTA WATERFOWL FOUNDATION
$500GENERAL SUPPORT
ANDEAN COMMUNITY PARTNERS
$500GENERAL SUPPORT
PSC PARTNERS SEEKING A CURE
$200GENERAL SUPPORT
MAYO CLINIC ROCHESTER
$489,500GRANT INSTALLMENTS FOR BIOBANK, CLINIC IMAGING, AND EXPOSOMICS
OSLO UNIVERSITY
$450,205SUPPORT BIOBANK AND CLINICAL TRIALS IN PSC
CONSTELLATION FUND
$252,565GRANT PROGRAM (3RD INSTALLMENT)
UNIVERSITY OF MINNESOTA FOUNDATION
$251,526WRESTLING SUPPORT
PSC PARTNERS SEEKING A CURE
$198,659GENERAL SUPPORT
NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH
$137,806PHD FELLOWSHIP SUPPORT
THE NATURE CONSERVANCY
$50,335GENERAL SUPPORT
CHILDREN'S THEATRE COMPANY
$50,335GENERAL SUPPORT
TWIN CITIES PUBLIC TELEVISION INC
$40,298GENERAL SUPPORT
DUCKS UNLIMITED INC
$25,167LIVING LAKES INITIATIVE
FREEDOM FROM RELIGION FOUNDATION
$10,127GENERAL SUPPORT
NATIONAL NATIVE AMERICAN BAR ASSOCIATION FOUNDATION
$10,000GENERAL SUPPORT
CONSTELLATION FUND
$10,000GENERAL SUPPORT
THREE RIVERS PAK DISTRICT FOUNDATION INC
$5,000GENERAL SUPPORT
MACPHAIL CENTER FOR MUSIC
$5,000GENERAL SUPPORT
RONALD MCDONALD HOUSE CHARITIES INC
$1,000GENERAL SUPPORT
RELEASE RECOVERY FOUNDATION
$1,000GENERAL SUPPORT
PSC PARTNERS SEEKING A CURE
$1,000GENERAL SUPPORT
MAYO CLINIC ROCHESTER
$663,532AI IMAGINING STUDY & PSC RESEARCH INITIATIVE
OSLO UNIVERSITY
$439,950SUPPORT BIOBANK INITIATIVE, NOPSC, AND PROJECT 42251
UNIVERSITY OF MINNESOTA FOUNDATION
$251,234WRESTLING PROGRAM SUPPORT
CONSTELLATION FUND
$250,063CONSTELLATION'S GRANT PROGRAM
PSC PARTNERS SEEKING A CURE
$203,819GENERAL SUPPORT
CHILDREN'S THEATRE COMPANY
$50,087GENERAL SUPPORT
TWIN CITIES PUBLIC TELEVISION INC
$40,079GENERAL SUPPORT FOR THE MINNESOTA EXPERIENCE
NOVARTIS INSTITUTE FOR BIOMEDICAL RESEARCH
$33,155PHD FELLOWSHIP SUPPORT
DUCKS UNLIMITED INC
$25,091LIVING LAKES INITIATIVE
FRIENDS OF NGONG ROAD
$15,000GENERAL SUPPORT
RELEASE RECOVERY FOUNDATION
$1,000GENERAL SUPPORT
MICHAEL J FOX FOUNDATION
$1,000GENERAL SUPPORT
PINE TREE APPLE CLASSIC FUND
$500GENERAL SUPPORT
DELANO AREA COUNCIL FOR ARTS AND CULTURE
$250GENERAL SUPPORT