To accelerate progress toward cures for childhood brain tumors and provide comprehensive support to children and families affected by pediatric brain cancer (Care. Cure. Thrive.).
A defining feature of Pediatric Brain Tumor Foundation of the United States Inc is its repeated support for the same research institutions across multiple years, especially Dana-Farber Cancer Institute, which received the largest recent award at $747,855 in 2025 and additional major grants in 2024 and 2023. That pattern points to a funder that backs sustained pediatric brain tumor research rather than isolated awards. The foundation’s stated purpose is to accelerate progress toward cures for childhood brain tumors and provide comprehensive support to children and families affected by pediatric brain cancer, and its active grant programs include seed funding for early-stage therapeutics, competitive research grants, and named partnership awards. Recent grants also show an emphasis on translational work, including precision medicine, patient-derived organoids, biomarker development, and preclinical testing. Beyond research institutions, the foundation funds early-career development, as seen in grants to Duke University, and collaborative projects designed to move promising science toward clinical relevance. Its grantmaking also reaches patient support and advocacy areas within the broader childhood brain tumor space.
Pediatric Brain Tumor Foundation of the United States Inc funds a mix of translational science and disease-specific research. In precision medicine, it gave $190,047 and $204,686 to Dana-Farber Cancer Institute for pediatric low-grade glioma projects studying tumor-brain interactions, MAPK inhibitor response, and rebound. For preclinical model development, it funded a Koschmann Grant to support patient-derived organoid work for pediatric brain tumors. The foundation also backed a collaborative award of $100,000 to maximize detection of childhood brain tumors in biofluids, linking liquid biopsy and relapse detection. Early-career development appears in $100,000 grants to Duke University. The portfolio also includes work on therapeutics, diagnostics, and translational pathways tied to pediatric brain tumor biology.
Typical grant size clusters around a median of $15,389, with a first quartile of $8,495 and a third quartile of $83,240, showing a mix of smaller project grants and larger research awards. The recent record also shows repeated support to the same recipients over multiple years, including Dana-Farber Cancer Institute, Regents of the University of Michigan, Saint Jude Childrens Research Hospital, and Washington University in St Louis. That points to ongoing relationships rather than one-time gifts. The foundation operates as a disease-focused funder and makes grants to institutions and individual researchers. It also accepts unsolicited applications through at least one active program, the PLGA Fund.
$1.3M
$3.3M
$5M
$6.7M
Most grants fall between $8K and $83K, with a median of $15K.
25th Percentile
$8K
Median
$15K
75th Percentile
$83K
About 9% of grants go to recipients in PA.
Geoff Still
Top 3 recipient countries by grant volume for Pediatric Brain Tumor Foundation of the United States.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 100 | $7.1M | 96.2% |
| 2 |
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Grantmaking is national, with 96.2% of recipient grants going to U.S. organizations and smaller shares to Canada and Germany. Pennsylvania is the top state by grant count, and one recent example there is Children's Hospital of Philadelphia. Other frequent recipient locations include Boston, Ann Arbor, Atlanta, Durham, and St. Louis. The foundation is headquartered in Winston Salem, NC, and 9% of grants go to recipients in North Carolina.
The foundation funds pediatric brain tumor research, family support and education, patient and family services, advocacy and policy, and clinical translation/precision medicine. Recent programs also include seed funding for early-stage pediatric drug development, patient-derived organoid work, liquid biopsy detection, and early-career development grants.
Yes. The recent grants list shows multi-year support to several institutions, including Dana-Farber Cancer Institute in 2023, 2024, and 2025, Regents of the University of Michigan in 2023, 2024, and 2025, and Washington University in St Louis in 2023 and 2024.
The listed grant-size distribution shows a p25 of $8,495, a median of $15,389, and a p75 of $83,240. The recent awards range from smaller project grants to larger research commitments, including six-figure awards for research institutions.
Giving is national, with 96.2% of recipient grants in the United States. Pennsylvania is the top state by grant count, while 9% of grants go to recipients in North Carolina.
Yes for at least one active program: the PLGA Fund is listed as accepting unsolicited applications. Other active research programs are listed as not accepting unsolicited applications.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| 2 |
| $110K |
1.9% |
| 3 | Germany | 2 | $70K | 1.9% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Current and upcoming funding from Pediatric Brain Tumor Foundation of the United States that your nonprofit may be able to apply for.
Who can apply: For researchers conducting pediatric brain tumor research, with this funding stream focused on pediatric low-grade gliomas and astrocytomas. Specific eligibility requirements are not provided.
Deadline: PBTF awards research grants on an ongoing basis; no specific deadline is provided.
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Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| Dana-Farber Cancer Institute | Boston, MA | $747,855 | 2025 | Research Grant |
| Regents of the University of Michigan | Ann Arbor, MI | $125,000 | 2025 | Research Grant |
| The Washington University | St Louis, MO | $124,480 | 2025 | Research Grant |
| TippingPoint Biosciences Inc | Los Altos, CA | $100,000 | 2025 | Research Grant |
| SonALAsense Inc | Oakland, CA | $100,000 | 2025 | Research Grant |
| St Jude Children's Research Hospital | Memphis, TN | $51,856 | 2025 | Research Grant |
| Children's Hospital of Philadelphia | Philadelphia, PA | $44,753 | 2025 | Research Grant |
| Society for Neuro-Oncology | Houston, TX | $40,000 | 2025 | Research Grant |
| DANA FARBER CANCER INSTITUTE | BOSTON, MA | $465,399 | 2024 | RESEARCH GRANT |
| Dana-Farber Cancer Institute | Boston, MA | $370,666 | 2024 | Research Grant |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $349,845 | 2024 | RESEARCH GRANT |
| SAINT JUDE CHILDRENS RESEARCH HOSPITAL | ATLANTA, GA | $250,000 | 2024 | RESEARCH GRANT |
| Children's Hospital of Philadelphia | Philadelphia, PA | $245,000 | 2024 | Research Grant |
| Public Health Institute | Oakland, CA | $200,000 | 2024 | Research Grant |
| Saint Jude Childrens Research Hospital | Memphis, TN | $200,000 | 2024 | Research Grant |
| Children's Healthcare of Atlanta | Atlanta, GA | $145,639 | 2024 | Research Grant |
| Nationawide Children's Hospital | Columbus, OH | $143,500 | 2024 | Research Grant |
| Regents of the University of Michigan | Ann Arbor, MI | $140,000 | 2024 | Research Grant |
| The Washington University | Saint Louis, MO | $118,079 | 2024 | Research Grant |
| DUKE UNIVERSITY | DURHAM, NC | $100,000 | 2024 | EARLY CAREER DEVELOPMENT |
| WASHINGTON UNIVERSITY IN ST LOUIS | STLOUIS, MO | $100,000 | 2024 | RESEARCH GRANT |
| UNIVERSITY OF CINCINNATI | CINCINNATI, OH | $100,000 | 2024 | RESEARCH GRANT |
| Vanderbilt University Medical Center | Nashville, TN | $97,500 | 2024 | Research Grant |
| SYDNEY'S INCREDIBLE DEFEAT OF EWING'S SARCOMA | WESTON, FL | $78,486 | 2024 | GRANT |
| American Assoication for Cancer Research | Philadelphia, PA | $66,000 | 2024 | Research Grant |
| AFLAC CANCER AND BLOOD DISORDER CENTER | ATLANTA, GA | $65,000 | 2024 | RESEARCH GRANT |
| CHOP RESEARCH INSTITUTE | PHILADELPHIA, PA | $64,000 | 2024 | SYMPOSIUM EXPENSES |
| CENTRAL BRAIN TUMOR REGISTRY OF THE UNITED STATES | HINSDALE, IL | $59,363 | 2024 | RESEARCH GRANT |
| SICKKIDS FOUNDATION | TORONTO, ON | $55,000 | 2024 | RESEARCH GRANT |
| Georgia State University Research Foundation | Atlatnta, GA | $53,810 | 2024 | Research Grant |
| EAST TENNESSEE CHILDREN'S HOSPITAL | KNOXVILLE, TN | $52,428 | 2024 | VS. CANCER GRANT |
| GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION | ATLANTA, GA | $52,239 | 2024 | RESEARCH GRANT |
| INTERPLAN CONGRESS MANAGEMENT - ISPNO | MUENCHEN | $35,105 | 2024 | RESEARCH GRANT |
| CHILDREN'S RESEARCH INSTITUTE | WASHINGTON, DC | $32,346 | 2024 | RESEARCH GRANT |
| CHOP Research Institute | PHILADELPHIA, PA | $30,000 | 2024 | Research Grant |
| Geisinger Janet Weis Children's Hospital | Danville, PA | $18,719 | 2024 | Vs. Cancer Grant |
| UNC LINEBERGER COMPREHENSIVE CANCER CENTER | CHAPEL HILL, NC | $15,389 | 2024 | VS. CANCER GRANT |
| OKLAHOMA CHILDREN'S HOSPITAL | OKLAHOMA CITY, OK | $14,089 | 2024 | VS. CANCER GRANT |
| Levine Children's Hospital | Charlotte, NC | $11,072 | 2024 | Vs. Cancer Grant |
| Noah Brave Foundation | Franklin, TN | $10,072 | 2024 | Vs. Cancer Grant |
| TOUGH2GETHER AGAINST DIPG CO AWOCCF | MANHATTAN, KS | $10,000 | 2024 | RESEARCH GRANT |
| ARMS WIDE OPEN CHILDHOOD CANCER FOUNDATION | MARLBORO, NJ | $10,000 | 2024 | VS. CANCER GRANT |
| Central Brain Tumor Registry of the United States | Hinsdale, IL | $10,000 | 2024 | Research Grant |
| Brenner Children's Hospital | Winston Salem, NC | $9,920 | 2024 | Vs. Cancer Grant |
| GEISINGER JANET WEIS CHILDREN'S HOSPITAL | DANVILLE, PA | $9,533 | 2024 | VS. CANCER GRANT |
| Baystate Children's Hospital | Springfield, MA | $9,527 | 2024 | Vs. Cancer Grant |
| BAYSTATE MEDICAL CENTER | SPRINGFIELD, MA | $9,316 | 2024 | VS. CANCER GRANT |
| CHILDREN'S HOSPITAL OF ILLINOIS | PEORIA, IL | $9,129 | 2024 | VS. CANCER GRANT |
| CHILDREN'S HEALTHCARE OF ATLANTA | ATLANTA, GA | $8,959 | 2024 | VS. CANCER GRANT |
| CAMP RONALD MCDONALD FOR GOOD TIMES | MOUNTAIN CENTER, CA | $8,750 | 2024 | VS. CANCER GRANT |
Regents of the University of Michigan
$125,000Research Grant
TippingPoint Biosciences Inc
$100,000Research Grant
SonALAsense Inc
$100,000Research Grant
Research Grant
Society for Neuro-Oncology
$40,000Research Grant
REGENTS OF THE UNIVERSITY OF MICHIGAN
$349,845RESEARCH GRANT
Regents of the University of Michigan
$140,000Research Grant
UNIVERSITY OF CINCINNATI
$100,000RESEARCH GRANT
SYDNEY'S INCREDIBLE DEFEAT OF EWING'S SARCOMA
$78,486GRANT
American Assoication for Cancer Research
$66,000Research Grant
CENTRAL BRAIN TUMOR REGISTRY OF THE UNITED STATES
$59,363RESEARCH GRANT
SICKKIDS FOUNDATION
$55,000RESEARCH GRANT
INTERPLAN CONGRESS MANAGEMENT - ISPNO
$35,105RESEARCH GRANT
CHILDREN'S RESEARCH INSTITUTE
$32,346RESEARCH GRANT
Geisinger Janet Weis Children's Hospital
$18,719Vs. Cancer Grant
UNC LINEBERGER COMPREHENSIVE CANCER CENTER
$15,389VS. CANCER GRANT
OKLAHOMA CHILDREN'S HOSPITAL
$14,089VS. CANCER GRANT
Noah Brave Foundation
$10,072Vs. Cancer Grant
Central Brain Tumor Registry of the United States
$10,000Research Grant
GEISINGER JANET WEIS CHILDREN'S HOSPITAL
$9,533VS. CANCER GRANT