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    3. Leducq Foundation for Cardiovascular Research
    Leducq Foundation for Cardiovascular Research logo

    Leducq Foundation for Cardiovascular Research

    ActiveMedical Research
    HOUSTON, TXWebsite7136272440

    About Leducq Foundation for Cardiovascular Research

    Improve human health through international efforts to combat cardiovascular disease and stroke by forging scientific alliances across national borders, educating young researchers, fostering long-term collaborative relationships and promoting innovation in cardiovascular and neurovascular research.

    Focus Areas

    Cardiovascular diseaseNeurovascular disease / strokeRheumatic heart diseaseGroup A Streptococcus research and vaccine developmentBiomarker discovery (acute rheumatic fever)Polymeric heart valve developmentTranslational researchCollaborative international networks of research

    Who They Fund

    not specified

    Funding Style

    unrestricted / general operating support

    About Leducq Foundation for Cardiovascular Research

    Leducq Foundation for Cardiovascular Research gives around cardiovascular and neurovascular science with a strong international structure: its flagship networks connect investigators across the Atlantic, while its rheumatic heart disease initiatives target Group A Streptococcus, biomarkers, vaccine development, and heart valve innovation. Recent grants show a broad research portfolio built around general support to major academic medical centers and universities, alongside programmatic work in specific disease areas. Among the largest recent awards are general-support grants to University of California Los Angeles, Stanford University, and the University of Pennsylvania, all of which appear multiple times in the recent grants list. That repetition points to an established pattern of sustained funding rather than isolated one-off awards. The foundation also supports named collaborative research programs, including International Networks of Excellence and Transatlantic Networks of Excellence, which are designed for multi-institution teams working in cardiovascular and neurovascular research. In the rheumatic heart disease portfolio, it backs targeted research streams that link immunology, translational work, and prevention.

    What Leducq Foundation for Cardiovascular Research Funds

    In cardiovascular and neurovascular research, the foundation backs large collaborative teams through its International Networks of Excellence and Transatlantic Networks of Excellence programs, both described as $7,000,000 awards over five years. For rheumatic heart disease, it supports targeted work on Group A Streptococcus immune correlates of protection and vaccine development, including foundation-funded initiatives with application instructions and timetables for participating researchers. It also funds the Acute Rheumatic Fever Biomarker Project, which is focused on biomarker discovery and validation within the foundation’s rheumatic heart disease priorities. Another targeted area is polymeric heart valve development, supported through the Rheumatic Heart Disease program. Across these areas, the pattern is translational and collaborative rather than site-specific or individual-centered.

    How Leducq Foundation for Cardiovascular Research Gives

    Typical grant sizes cluster in the mid-six figures: the 25th percentile is $79,455, the median is $151,725, and the 75th percentile is $275,020. The recent grants list also shows repeated awards to the same institutions across multiple years, including Stanford University, University of Pennsylvania, Northwestern University, University of California Los Angeles, and others, which suggests recurring institutional relationships rather than one-time support. The foundation is a regular funder and does not fund individuals or make program-related investments. Some programs accept unsolicited proposals, including the Transatlantic Networks of Excellence and the Rheumatic Heart Disease Acute Rheumatic Fever Biomarker Project, while other targeted streams are listed as not accepting unsolicited applications.

    Financial Snapshot

    Annual Giving

    $25.6M

    Total Assets

    $88.4M

    Total Revenue

    $40.5M

    Total Expenses

    $26.2M

    Typical Grant Size

    Most grants fall between $79K and $275K, with a median of $152K.

    25th Percentile

    $79K

    Median

    $152K

    75th Percentile

    $275K

    Geographic Reach

    National27 states funded

    About 6% of grants go to recipients in CA.

    Funding intensity
    Low
    High
    Headquarters
    Funding intensity
    Low
    High

    Where Leducq Foundation for Cardiovascular Research Funds

    Top 10 recipient countries by grant volume for Leducq Foundation for Cardiovascular Research.

    RankCountryGrantsTotalShare
    1United StatesDomestic150$39.3M
    42.7%
    2Germany45$10.3M

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    EIN: 45-4696263
    3 filings on record
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    core operating support
    non-restricted funding

    Topics

    no specific programmatic focusorganizational capacity across programscross-cutting support (applies to any mission area)

    Where Leducq Foundation for Cardiovascular Research Makes Grants

    Grant recipients are primarily in the United States, which accounts for 150 grants, or 42.7% of the recipient-country total. Outside the U.S., grants also land in Germany, the UK, the Netherlands, Italy, Switzerland, France, Spain, Canada, and Denmark. Among recent recipients, cities include Los Angeles, Stanford, Philadelphia, Evanston, Dallas, Madrid, Berlin, Charlottesville, New Haven, and Baltimore. The top state by grant count is California, and 6% of grants go to recipients in Texas, the foundation’s headquarters state.

    Frequently Asked Questions About Leducq Foundation for Cardiovascular Research

    What does Leducq Foundation for Cardiovascular Research fund?

    It funds cardiovascular and neurovascular research, along with rheumatic heart disease initiatives. Recent and programmatic support includes general support to research institutions, Transatlantic Networks of Excellence, Group A Streptococcus vaccine-related work, biomarker projects for acute rheumatic fever, and polymeric heart valve development.

    What is the foundation’s typical grant size?

    The middle of its grant-size distribution is in the mid-six figures: the 25th percentile is $79,455, the median is $151,725, and the 75th percentile is $275,020.

    Does the foundation fund recurring grantees?

    Yes. Several institutions appear more than once in the recent grants list, including Stanford University, University of Pennsylvania, Northwestern University, University of California Los Angeles, and University of Virginia. That pattern indicates sustained relationships across years.

    What kinds of collaborative programs does it support?

    It supports international and transatlantic research networks in cardiovascular and neurovascular disease. The International Networks of Excellence and Transatlantic Networks of Excellence programs are described as $7,000,000 awards over five years for multi-institution teams.

    How does the foundation handle applications for targeted programs?

    Some targeted programs accept unsolicited proposals, including the Transatlantic Networks of Excellence program and the Acute Rheumatic Fever Biomarker Project. Other rheumatic heart disease streams are listed as not accepting unsolicited applications.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    12.8%
    3United Kingdom27$6.3M
    7.7%
    4Netherlands22$4.3M
    6.3%
    5Italy16$2.3M
    4.6%
    6Sweden11$2.1M
    3.1%
    7France10$1.1M
    2.9%
    8Spain9$2.4M
    2.6%
    9Denmark8$869K
    2.3%
    10Canada8$832K
    2.3%

    Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    UNIVERSITY OF CALIFORNIA LOS ANGELESLOS ANGELES, CA$1,302,6342025GENERAL SUPPORT
    UNIVERSITY OF PENNSYLVANIAPHILADELPHIA, PA$1,168,9222025GENERAL SUPPORT
    STANFORD UNIVERSITYSTANFORD, CA$1,010,1592025GENERAL SUPPORT
    NORTHWESTERN UNIVERSITYEVANSTON, IL$1,008,5942025GENERAL SUPPORT
    UNIVERSITY OF VIRGINIACHARLOTTESVILLE, VA$806,8072025GENERAL SUPPORT
    UT SOUTHWESTERN MEDICAL CENTER AT DALLASDALLAS, TX$706,7032025GENERAL SUPPORT
    LMU KLINKIKUM DER UNIVERSITAT MUNCHENMUNCHEN$587,3862025GENERAL SUPPORT
    WASHINGTON UNIVERSITY IN ST LOUISST LOUIS, MO$576,3602025GENERAL SUPPORT
    CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (FSP)MADRID$563,1792025GENERAL SUPPORT
    THE UNIVERSITY OF EDINBURGHEDINBURGH$514,2742025GENERAL SUPPORT
    CHARITE UNIVERSITATSMEDIZIN BERLINBERLIN$501,4242025GENERAL SUPPORT
    UNIVERSITY OF OXFORDOXFORD$499,9152025GENERAL SUPPORT
    MASSACHUSETTS GENERAL HOSPITALBOSTON, MA$497,3702025GENERAL SUPPORT
    MAX DELBRUCK CENTRE FOR MOLECULAR MEDICINEBERLIN$491,9302025GENERAL SUPPORT
    THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTONHOUSTON, TX$466,9282025GENERAL SUPPORT
    COLUMBIA UNIVERSITYNEW YORK, NY$445,5662025GENERAL SUPPORT
    UNIVERSITY OF COLORADO - BOULDERDENVER, CO$422,3862025GENERAL SUPPORT
    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAINEW YORK, NY$417,7342025GENERAL SUPPORT
    KAROLINSKA INSTITUTETSTOCKHOLM$391,7242025GENERAL SUPPORT
    JOHNS HOPKINS UNIVERSITYBALTIMORE, MD$378,3752025GENERAL SUPPORT
    IMPERIAL COLLEGE LONDONLONDON$351,7192025GENERAL SUPPORT
    UNIVERSITY MEDICAL CENTER GOTTINGENGOTTINGEN$341,3012025GENERAL SUPPORT
    YALE UNIVERSITYNEW HAVEN, CT$322,5702025GENERAL SUPPORT
    UNIVERSITY OF CAMBRIDGECAMBRIDGE$311,6282025GENERAL SUPPORT
    THE UNIVERSITY OF MANCHESTERMANCHESTER$294,3232025GENERAL SUPPORT
    BETH ISRAEL DEACONESS MEDICAL CENTERBOSTON, MA$292,3412025GENERAL SUPPORT
    TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTDHAIFA$287,0902025GENERAL SUPPORT
    UNIVERSITY MEDICAL CENTER UTRECHTUTRECHT$283,7382025GENERAL SUPPORT
    NETHERLANDS HEART INSTITUTEUTRECHT$281,7312025GENERAL SUPPORT
    HEIDELBERG UNIVERSITYHEIDELBERG$273,9362025GENERAL SUPPORT
    MEDIZINISCHE UNIVERSITAT WIENWIEN$271,1452025GENERAL SUPPORT
    INSERMPARIS$246,8002025GENERAL SUPPORT
    THE OHIO STATE UNIVERSITYDETROIT, MI$246,0422025GENERAL SUPPORT
    REGENTS OF THE UNIVERSITY OF MINNESOTA-TWIN CITIESMINNEAPOLIS, MN$227,4902025GENERAL SUPPORT
    DE DUVE INSTITUTEBRUSSELS$216,4102025GENERAL SUPPORT
    UNIVERSITY OF HAMBURG-EPPENDORFHAMBURG$215,6142025GENERAL SUPPORT
    AMSTERDAM UNIVERSITY MEDICAL CENTERAMSTERDAM$211,6712025GENERAL SUPPORT
    INSTITUTO DE MEDICINA MOLECULARLISBON$203,0132025GENERAL SUPPORT
    FONDAZIONE PER LA RICERCA BIOMEDICA ONLUSTORINO$202,5212025GENERAL SUPPORT
    UNIVERSITY OF POTSDAMPOTSDAM$201,3942025GENERAL SUPPORT
    WEILL CORNELL MEDICAL COLLEGENEW YORK, NY$200,7612025GENERAL SUPPORT
    KYOTO UNIVERSITYSAKYOKU$198,0602025GENERAL SUPPORT
    HANNOVER MEDICAL SCHOOLHANOVER$197,4312025GENERAL SUPPORT
    ISTITUTO AUXOLOGICO ITALIANOMILANO$195,1172025GENERAL SUPPORT
    NATIONAL HEART LUNG AND BLOOD INSTITUTEBETHESDA, MD$191,5982025GENERAL SUPPORT
    VANDERBILT UNIVERSITY MEDICAL CENTERDALLAS, TX$190,9222025GENERAL SUPPORT
    UNIVERSITY OF LEICESTERLEICESTER$190,8802025GENERAL SUPPORT
    CLEVELAND CLINIC FOUNDATIONCLEVELAND, OH$187,0002025GENERAL SUPPORT
    THE UNIVERSITY OF ARIZONATUCSON, AZ$178,0542025GENERAL SUPPORT
    UNIVERSITA DEGLI STUDI DI MILANOMILANO$177,7752025GENERAL SUPPORT

    UNIVERSITY OF CALIFORNIA LOS ANGELES

    $1,302,634
    LOS ANGELES, CA2025

    GENERAL SUPPORT

    UNIVERSITY OF PENNSYLVANIA

    $1,168,922
    PHILADELPHIA, PA2025

    GENERAL SUPPORT

    STANFORD UNIVERSITY

    $1,010,159
    STANFORD, CA2025

    GENERAL SUPPORT

    NORTHWESTERN UNIVERSITY

    $1,008,594
    EVANSTON, IL2025

    GENERAL SUPPORT

    UNIVERSITY OF VIRGINIA

    $806,807
    CHARLOTTESVILLE, VA2025

    GENERAL SUPPORT

    UT SOUTHWESTERN MEDICAL CENTER AT DALLAS

    $706,703
    DALLAS, TX2025

    GENERAL SUPPORT

    LMU KLINKIKUM DER UNIVERSITAT MUNCHEN

    $587,386
    MUNCHEN2025

    GENERAL SUPPORT

    WASHINGTON UNIVERSITY IN ST LOUIS

    $576,360
    ST LOUIS, MO2025

    GENERAL SUPPORT

    CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (FSP)

    $563,179
    MADRID2025

    GENERAL SUPPORT

    THE UNIVERSITY OF EDINBURGH

    $514,274
    EDINBURGH2025

    GENERAL SUPPORT

    CHARITE UNIVERSITATSMEDIZIN BERLIN

    $501,424
    BERLIN2025

    GENERAL SUPPORT

    UNIVERSITY OF OXFORD

    $499,915
    OXFORD2025

    GENERAL SUPPORT

    MASSACHUSETTS GENERAL HOSPITAL

    $497,370
    BOSTON, MA2025

    GENERAL SUPPORT

    MAX DELBRUCK CENTRE FOR MOLECULAR MEDICINE

    $491,930
    BERLIN2025

    GENERAL SUPPORT

    THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON

    $466,928
    HOUSTON, TX2025

    GENERAL SUPPORT

    COLUMBIA UNIVERSITY

    $445,566
    NEW YORK, NY2025

    GENERAL SUPPORT

    UNIVERSITY OF COLORADO - BOULDER

    $422,386
    DENVER, CO2025

    GENERAL SUPPORT

    ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI

    $417,734
    NEW YORK, NY2025

    GENERAL SUPPORT

    KAROLINSKA INSTITUTET

    $391,724
    STOCKHOLM2025

    GENERAL SUPPORT

    JOHNS HOPKINS UNIVERSITY

    $378,375
    BALTIMORE, MD2025

    GENERAL SUPPORT

    IMPERIAL COLLEGE LONDON

    $351,719
    LONDON2025

    GENERAL SUPPORT

    UNIVERSITY MEDICAL CENTER GOTTINGEN

    $341,301
    GOTTINGEN2025

    GENERAL SUPPORT

    YALE UNIVERSITY

    $322,570
    NEW HAVEN, CT2025

    GENERAL SUPPORT

    UNIVERSITY OF CAMBRIDGE

    $311,628
    CAMBRIDGE2025

    GENERAL SUPPORT

    THE UNIVERSITY OF MANCHESTER

    $294,323
    MANCHESTER2025

    GENERAL SUPPORT

    BETH ISRAEL DEACONESS MEDICAL CENTER

    $292,341
    BOSTON, MA2025

    GENERAL SUPPORT

    TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD

    $287,090
    HAIFA2025

    GENERAL SUPPORT

    UNIVERSITY MEDICAL CENTER UTRECHT

    $283,738
    UTRECHT2025

    GENERAL SUPPORT

    NETHERLANDS HEART INSTITUTE

    $281,731
    UTRECHT2025

    GENERAL SUPPORT

    HEIDELBERG UNIVERSITY

    $273,936
    HEIDELBERG2025

    GENERAL SUPPORT

    MEDIZINISCHE UNIVERSITAT WIEN

    $271,145
    WIEN2025

    GENERAL SUPPORT

    INSERM

    $246,800
    PARIS2025

    GENERAL SUPPORT

    THE OHIO STATE UNIVERSITY

    $246,042
    DETROIT, MI2025

    GENERAL SUPPORT

    REGENTS OF THE UNIVERSITY OF MINNESOTA-TWIN CITIES

    $227,490
    MINNEAPOLIS, MN2025

    GENERAL SUPPORT

    DE DUVE INSTITUTE

    $216,410
    BRUSSELS2025

    GENERAL SUPPORT

    UNIVERSITY OF HAMBURG-EPPENDORF

    $215,614
    HAMBURG2025

    GENERAL SUPPORT

    AMSTERDAM UNIVERSITY MEDICAL CENTER

    $211,671
    AMSTERDAM2025

    GENERAL SUPPORT

    INSTITUTO DE MEDICINA MOLECULAR

    $203,013
    LISBON2025

    GENERAL SUPPORT

    FONDAZIONE PER LA RICERCA BIOMEDICA ONLUS

    $202,521
    TORINO2025

    GENERAL SUPPORT

    UNIVERSITY OF POTSDAM

    $201,394
    POTSDAM2025

    GENERAL SUPPORT

    WEILL CORNELL MEDICAL COLLEGE

    $200,761
    NEW YORK, NY2025

    GENERAL SUPPORT

    KYOTO UNIVERSITY

    $198,060
    SAKYOKU2025

    GENERAL SUPPORT

    HANNOVER MEDICAL SCHOOL

    $197,431
    HANOVER2025

    GENERAL SUPPORT

    ISTITUTO AUXOLOGICO ITALIANO

    $195,117
    MILANO2025

    GENERAL SUPPORT

    NATIONAL HEART LUNG AND BLOOD INSTITUTE

    $191,598
    BETHESDA, MD2025

    GENERAL SUPPORT

    VANDERBILT UNIVERSITY MEDICAL CENTER

    $190,922
    DALLAS, TX2025

    GENERAL SUPPORT

    UNIVERSITY OF LEICESTER

    $190,880
    LEICESTER2025

    GENERAL SUPPORT

    CLEVELAND CLINIC FOUNDATION

    $187,000
    CLEVELAND, OH2025

    GENERAL SUPPORT

    THE UNIVERSITY OF ARIZONA

    $178,054
    TUCSON, AZ2025

    GENERAL SUPPORT

    UNIVERSITA DEGLI STUDI DI MILANO

    $177,775
    MILANO2025

    GENERAL SUPPORT