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    5. Dr Miriam & Sheldon G Adelson Medical Research Foundation
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    Dr Miriam & Sheldon G Adelson Medical Research Foundation

    ActivePhilanthropy & Voluntarism
    NEEDHAM, MAWebsite7819725900

    About Dr Miriam & Sheldon G Adelson Medical Research Foundation

    The Dr. Miriam & Sheldon G. Adelson Medical Research Foundation concentrates almost all of its funding on biomedical and cancer research at leading academic and research medical centers. Grants are large, targeted awards to established institutions and centers of excellence (often supporting specific medical research programs or labs), indicating a preference for high-impact, translational science rather than community service or small operating support. The foundation repeatedly funds the same top universities and cancer centers, suggesting long-term investments in institutional research capacity and major projects in oncology and genomics.

    Focus Areas

    Translational cancer research at major academic medical centersUniversity-based biomedical research programs and labsGenomics and precision medicine research (infrastructure and core projects)Large-scale research partnerships between elite institutions

    Who They Fund

    medical researchers/scientistsacademic research institutionshospitals and clinical research centers

    Giving Approach

    About Dr Miriam & Sheldon G Adelson Medical Research Foundation

    The Dr Miriam & Sheldon G Adelson Medical Research Foundation’s recent awards are dominated by multimillion-dollar gifts to academic medical centers for medical research, with University of California Los Angeles receiving the largest listed grant at $4,982,102 in 2025. The pattern is institutionally focused: the foundation directs major support to established hospitals, cancer institutes, and research universities rather than to individuals or small community groups. In the recent-grants list, MD Anderson Cancer Center, Johns Hopkins University, Dana Farber Cancer Institute, The Broad Institute, and the University of California system all appear as recipients, showing a preference for large research organizations with depth in biomedical science. Several awards go to cancer-focused centers, while others support broader translational and genomics-oriented work at major universities and institutes. The foundation’s own program structure also points to a research-driven model, including investigator grants that invite selected scientists into collaborative, disease-agnostic projects. Alongside its medical research activity, the foundation also maintains program areas in Holocaust remembrance and anti-Semitism awareness, welfare, Israel programs, Israel advocacy, and Jewish and Zionist identity & education.

    What Dr Miriam & Sheldon G Adelson Medical Research Foundation Funds

    Medical research is the clearest throughline. The foundation gave $3,353,535 in 2025 to MD Anderson Cancer Center for medical research, and $2,936,328 in 2025 to Dana Farber Cancer Institute for the same purpose. It also supported translational and collaborative science through awards to institutions such as The Broad Institute and Johns Hopkins University, consistent with a model that favors large research teams and established labs. Its grantmaking is not limited to one disease area. Grants also went to the University of Southern California and the University of California Los Angeles for medical research, showing support across major academic medical centers. Outside the research portfolio, the foundation funds Holocaust and Anti-Semitism Awareness, Welfare, Israel Programs, Israel Advocacy, Social Services and Health, and Jewish and Zionist Identity & Education through separate program areas.

    How Dr Miriam & Sheldon G Adelson Medical Research Foundation Gives

    Financial Snapshot

    Annual Giving

    $40.8M

    Total Assets

    $714K

    Total Revenue

    $42.1M

    Total Expenses

    $42.8M

    Typical Grant Size

    Most grants fall between $368K and $1.3M, with a median of $512K.

    25th Percentile

    $368K

    Median

    $512K

    75th Percentile

    $1.3M

    Geographic Reach

    National12 states funded

    About 21% of grants go to recipients in MA.

    Funding intensity
    Low
    High
    Headquarters
    Funding intensity
    Low
    High

    Where Dr Miriam & Sheldon G Adelson Medical Research Foundation Funds

    Top 4 recipient countries by grant volume for Dr Miriam & Sheldon G Adelson Medical Research Foundation.

    RankCountryGrantsTotalShare
    1United StatesDomestic64$67.8M
    85.3%
    2Israel6

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    EIN: 04-7023433
    2 filings on record
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    Highly concentrated giving: a small number of very large grants, often repeated to the same elite research institutions; funds tend to support programmatic/ research projects rather than general operating or grassroots organizations.

    Funding Style

    research grant fundingproject-specific scientific supportbiomedical research investment

    Notable grantees: University of California, Los Angeles, Johns Hopkins University, MD Anderson Cancer Center, The Broad Institute, Dana-Farber Cancer Institute

    Topics

    medical researchbiomedical researchclinical research/clinical trialstranslational researchdisease-focused investigation

    Typical grant sizes are substantial: the p25 is $367,700, the median is $511,548, and the p75 is $1,284,980. That distribution matches a model built around large institutional awards rather than many small grants. The recent-grants list also shows repeat support to the same organizations across multiple years, including University of California Los Angeles, Johns Hopkins University, The Broad Institute, MD Anderson Cancer Center, Dana Farber Cancer Institute, and Oregon Health and Science University. The foundation is a regular funder, not a DAF, and it does not fund individuals or make program-related investments. Its medical research programs are invitation-based and collaborative rather than open solicitation.

    Where Dr Miriam & Sheldon G Adelson Medical Research Foundation Makes Grants

    Most grants go to recipients in the United States, which account for 64 grants, or 85.3% of the recent list. Massachusetts is the top state by grant count, and 21% of grants go to recipients there, including organizations in Boston, Brookline, and Cambridge. Outside the U.S., the recent-grants list includes recipients in Israel, the United Kingdom, and Germany; named locations include Rehovot, Jerusalem, Haifa, London, and one grant to an institution in Germany (GM). The map of giving reflects a national U.S. footprint with concentrated institutional clusters in California, Massachusetts, and Maryland.

    Frequently Asked Questions About Dr Miriam & Sheldon G Adelson Medical Research Foundation

    What kinds of organizations does the foundation fund most often?

    It mainly funds medical research organizations, especially universities, cancer centers, and clinical research institutions. The recent-grants list includes awards to University of California Los Angeles, Johns Hopkins University, Dana Farber Cancer Institute, The Broad Institute, and MD Anderson Cancer Center, all for medical research.

    How large are the foundation’s typical grants?

    The grant-size distribution is high-dollar: p25 is $367,700, median grant size is $511,548, and p75 is $1,284,980. Recent awards also reach into the multimillion-dollar range, which fits a strategy centered on major institutional research support.

    Does the foundation give to the same grantees more than once?

    Yes. Several recipients appear in multiple years, including University of California Los Angeles in 2023 and 2025, Johns Hopkins University in 2023 and 2025, The Broad Institute in 2023 and 2025, and MD Anderson Cancer Center in 2023 and 2025.

    Which countries receive most of the foundation’s grants?

    The United States receives the overwhelming majority, with 64 grants or 85.3% of the recent list. Israel is the next most common destination with 6 grants, followed by Germany with 3 and the United Kingdom with 2.

    Does the foundation accept unsolicited applications?

    For the medical research programs listed, the process is invitation-based: the AMRF Investigator Grants and the Investigator / Collaborative Research Program identify and invite investigators to develop collaborative projects, and both are marked as not accepting unsolicited applications.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    $5.5M
    8.0%
    3Germany3$988K
    4.0%
    4United Kingdom2$972K
    2.7%

    Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    UNIVERSITY OF CALIFORNIA LOS ANGELESLOS ANGELES, CA$4,982,1022025MEDICAL RESEARCH
    MD ANDERSON CANCER CENTERHOUSTON, TX$3,353,5352025MEDICAL RESEARCH
    JOHNS HOPKINS UNIVERSITYBALTIMORE, MD$3,133,4852025MEDICAL RESEARCH
    DANA FARBER CANCER INSTITUTEBROOKLINE, MA$2,936,3282025MEDICAL RESEARCH
    THE BROAD INSTITUTECAMBRIDGE, MA$2,655,9762025MEDICAL RESEARCH
    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SFSAN FRANCISCO, CA$2,491,7382025MEDICAL RESEARCH
    ST JOHNS CANCER INSTITUTESANTA MONICA, CA$1,773,0252025MEDICAL RESEARCH
    UNIVERSITY OF SOUTHERN CALIFORNIALOS ANGELES, CA$1,599,7452025MEDICAL RESEARCH
    WEIZMANN INSTITUTE OF SCIENCEREHOVOT$1,505,8772025MEDICAL RESEARCH
    OREGON HEALTH AND SCIENCE UNIVERSITYPORTLAND, OR$1,494,5862025MEDICAL RESEARCH
    MASSACHUSETTS GENERAL HOSPITALBOSTON, MA$1,252,5962025MEDICAL RESEARCH
    CEDARS SINAILOS ANGELES, CA$1,200,0222025MEDICAL RESEARCH
    BOSTON CHILDREN'S HOSPITAL TRUSTBOSTON, MA$936,3872025MEDICAL RESEARCH
    IMPERIAL COLLEGE OF LONDONLONDON$800,8882025MEDICAL RESEARCH
    HEBREW UNIVERSITY OF JERUSALEMJERUSALEM$767,8492025MEDICAL RESEARCH
    UNIVERSITY OF PENNSYLVANIAPHILADELPHIA, PA$765,6872025MEDICAL RESEARCH
    TEL AVIV UNIVERSITYTEL AVIV$752,0102025MEDICAL RESEARCH
    H LEE MOFFITT CANCER CENTERTAMPA, FL$750,8482025MEDICAL RESEARCH
    UNIVERSITY OF ROCHESTERROCHESTER, NY$699,4472025MEDICAL RESEARCH
    HADASSAH HEBREW UNIVERSITYJERUSALEM$648,6252025MEDICAL RESEARCH
    HARVARD MEDICAL SCHOOLBOSTON, MA$483,5872025MEDICAL RESEARCH
    THE WISTAR INSTITUTEPHILADELPHIA, PA$453,4062025MEDICAL RESEARCH
    UNIVERSITY OF CALIFORNIA SAN DIEGOLA JOLLA, CA$425,0002025MEDICAL RESEARCH
    SOUTH CAROLINA RESEARCH FOUNDATIONCOLUMBIA, SC$402,1062025MEDICAL RESEARCH
    THE REGENTS OF THE UNIVERSITY OF MICHIGANANN ARBOR, MI$396,7772025MEDICAL RESEARCH
    DUKE UNIVERSITYDURHAM, NC$377,0042025MEDICAL RESEARCH
    UNIVERSITY OF MINNESOTAMINNEAPOLIS, MN$375,0002025MEDICAL RESEARCH
    THE WINIFRED MASTERSON BURKE NEUROLOGICAL INSTITUTEWHITE PLAINS, NY$375,0002025MEDICAL RESEARCH
    THOMAS JEFFERSON UNIVERSITYPHILADELPHIA, PA$366,7172025MEDICAL RESEARCH
    NATIONAL INSTITUTE OF HEALTHBETHESDA, MD$349,9602025MEDICAL RESEARCH
    DZNE MUNICHBONN$342,6662025MEDICAL RESEARCH
    TECHNION ISRAEL INSTITUTE OF TECHNOLOGYHAIFA$338,5002025MEDICAL RESEARCH
    MAX PLANCK INSTITUTEGOTTINGEN$334,5012025MEDICAL RESEARCH
    BAYLOR COLLEGE OF MEDICINEHOUSTON, TX$311,8892025MEDICAL RESEARCH
    LEIPZIG UNIVERSITYLEIPZIG$311,1452025MEDICAL RESEARCH
    UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOLWORCESTER, MA$306,7892025MEDICAL RESEARCH
    NORTHWESTERN UNIVERSITYCHICAGO, IL$182,9452025MEDICAL RESEARCH
    UNIVERSITY OF CAMBRIDGECAMBRIDGE$170,9342025MEDICAL RESEARCH
    UNIVERSITY OF CALIFORNIA LOS ANGELESLOS ANGELES, CA$3,991,9762023MEDICAL RESEARCH
    JOHNS HOPKINS UNIVERSITYBALTIMORE, MD$3,128,5112023MEDICAL RESEARCH
    THE BROAD INSTITUTECAMBRIDGE, MA$2,554,3912023MEDICAL RESEARCH
    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SFSAN FRANCISCO, CA$2,456,0032023MEDICAL RESEARCH
    MD ANDERSON CANCER CENTERHOUSTON, TX$2,161,2102023MEDICAL RESEARCH
    DANA FARBER CANCER INSTITUTEBROOKLINE, MA$1,655,9852023MEDICAL RESEARCH
    WEIZMANN INSTITUTE OF SCIENCEREHOVOT$1,498,1132023MEDICAL RESEARCH
    ST JOHNS CANCER INSTITUTESANTA MONICA, CA$1,446,3712023MEDICAL RESEARCH
    MASSACHUSETTS GENERAL HOSPITALBOSTON, MA$1,297,4262023MEDICAL RESEARCH
    UNIVERSITY OF SOUTHERN CALIFORNIALOS ANGELES, CA$1,284,9802023MEDICAL RESEARCH
    BOSTON CHILDREN'S HOSPITAL TRUSTBOSTON, MA$1,159,9972023MEDICAL RESEARCH
    OREGON HEALTH AND SCIENCE UNIVERSITYPORTLAND, OR$1,126,3132023MEDICAL RESEARCH

    UNIVERSITY OF CALIFORNIA LOS ANGELES

    $4,982,102
    LOS ANGELES, CA2025

    MEDICAL RESEARCH

    MD ANDERSON CANCER CENTER

    $3,353,535
    HOUSTON, TX2025

    MEDICAL RESEARCH

    JOHNS HOPKINS UNIVERSITY

    $3,133,485
    BALTIMORE, MD2025

    MEDICAL RESEARCH

    DANA FARBER CANCER INSTITUTE

    $2,936,328
    BROOKLINE, MA2025

    MEDICAL RESEARCH

    THE BROAD INSTITUTE

    $2,655,976
    CAMBRIDGE, MA2025

    MEDICAL RESEARCH

    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SF

    $2,491,738
    SAN FRANCISCO, CA2025

    MEDICAL RESEARCH

    ST JOHNS CANCER INSTITUTE

    $1,773,025
    SANTA MONICA, CA2025

    MEDICAL RESEARCH

    UNIVERSITY OF SOUTHERN CALIFORNIA

    $1,599,745
    LOS ANGELES, CA2025

    MEDICAL RESEARCH

    WEIZMANN INSTITUTE OF SCIENCE

    $1,505,877
    REHOVOT2025

    MEDICAL RESEARCH

    OREGON HEALTH AND SCIENCE UNIVERSITY

    $1,494,586
    PORTLAND, OR2025

    MEDICAL RESEARCH

    MASSACHUSETTS GENERAL HOSPITAL

    $1,252,596
    BOSTON, MA2025

    MEDICAL RESEARCH

    CEDARS SINAI

    $1,200,022
    LOS ANGELES, CA2025

    MEDICAL RESEARCH

    BOSTON CHILDREN'S HOSPITAL TRUST

    $936,387
    BOSTON, MA2025

    MEDICAL RESEARCH

    IMPERIAL COLLEGE OF LONDON

    $800,888
    LONDON2025

    MEDICAL RESEARCH

    HEBREW UNIVERSITY OF JERUSALEM

    $767,849
    JERUSALEM2025

    MEDICAL RESEARCH

    UNIVERSITY OF PENNSYLVANIA

    $765,687
    PHILADELPHIA, PA2025

    MEDICAL RESEARCH

    TEL AVIV UNIVERSITY

    $752,010
    TEL AVIV2025

    MEDICAL RESEARCH

    H LEE MOFFITT CANCER CENTER

    $750,848
    TAMPA, FL2025

    MEDICAL RESEARCH

    UNIVERSITY OF ROCHESTER

    $699,447
    ROCHESTER, NY2025

    MEDICAL RESEARCH

    HADASSAH HEBREW UNIVERSITY

    $648,625
    JERUSALEM2025

    MEDICAL RESEARCH

    HARVARD MEDICAL SCHOOL

    $483,587
    BOSTON, MA2025

    MEDICAL RESEARCH

    THE WISTAR INSTITUTE

    $453,406
    PHILADELPHIA, PA2025

    MEDICAL RESEARCH

    UNIVERSITY OF CALIFORNIA SAN DIEGO

    $425,000
    LA JOLLA, CA2025

    MEDICAL RESEARCH

    SOUTH CAROLINA RESEARCH FOUNDATION

    $402,106
    COLUMBIA, SC2025

    MEDICAL RESEARCH

    THE REGENTS OF THE UNIVERSITY OF MICHIGAN

    $396,777
    ANN ARBOR, MI2025

    MEDICAL RESEARCH

    DUKE UNIVERSITY

    $377,004
    DURHAM, NC2025

    MEDICAL RESEARCH

    UNIVERSITY OF MINNESOTA

    $375,000
    MINNEAPOLIS, MN2025

    MEDICAL RESEARCH

    THE WINIFRED MASTERSON BURKE NEUROLOGICAL INSTITUTE

    $375,000
    WHITE PLAINS, NY2025

    MEDICAL RESEARCH

    THOMAS JEFFERSON UNIVERSITY

    $366,717
    PHILADELPHIA, PA2025

    MEDICAL RESEARCH

    NATIONAL INSTITUTE OF HEALTH

    $349,960
    BETHESDA, MD2025

    MEDICAL RESEARCH

    DZNE MUNICH

    $342,666
    BONN2025

    MEDICAL RESEARCH

    TECHNION ISRAEL INSTITUTE OF TECHNOLOGY

    $338,500
    HAIFA2025

    MEDICAL RESEARCH

    MAX PLANCK INSTITUTE

    $334,501
    GOTTINGEN2025

    MEDICAL RESEARCH

    BAYLOR COLLEGE OF MEDICINE

    $311,889
    HOUSTON, TX2025

    MEDICAL RESEARCH

    LEIPZIG UNIVERSITY

    $311,145
    LEIPZIG2025

    MEDICAL RESEARCH

    UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL

    $306,789
    WORCESTER, MA2025

    MEDICAL RESEARCH

    NORTHWESTERN UNIVERSITY

    $182,945
    CHICAGO, IL2025

    MEDICAL RESEARCH

    UNIVERSITY OF CAMBRIDGE

    $170,934
    CAMBRIDGE2025

    MEDICAL RESEARCH

    UNIVERSITY OF CALIFORNIA LOS ANGELES

    $3,991,976
    LOS ANGELES, CA2023

    MEDICAL RESEARCH

    JOHNS HOPKINS UNIVERSITY

    $3,128,511
    BALTIMORE, MD2023

    MEDICAL RESEARCH

    THE BROAD INSTITUTE

    $2,554,391
    CAMBRIDGE, MA2023

    MEDICAL RESEARCH

    THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SF

    $2,456,003
    SAN FRANCISCO, CA2023

    MEDICAL RESEARCH

    MD ANDERSON CANCER CENTER

    $2,161,210
    HOUSTON, TX2023

    MEDICAL RESEARCH

    DANA FARBER CANCER INSTITUTE

    $1,655,985
    BROOKLINE, MA2023

    MEDICAL RESEARCH

    WEIZMANN INSTITUTE OF SCIENCE

    $1,498,113
    REHOVOT2023

    MEDICAL RESEARCH

    ST JOHNS CANCER INSTITUTE

    $1,446,371
    SANTA MONICA, CA2023

    MEDICAL RESEARCH

    MASSACHUSETTS GENERAL HOSPITAL

    $1,297,426
    BOSTON, MA2023

    MEDICAL RESEARCH

    UNIVERSITY OF SOUTHERN CALIFORNIA

    $1,284,980
    LOS ANGELES, CA2023

    MEDICAL RESEARCH

    BOSTON CHILDREN'S HOSPITAL TRUST

    $1,159,997
    BOSTON, MA2023

    MEDICAL RESEARCH

    OREGON HEALTH AND SCIENCE UNIVERSITY

    $1,126,313
    PORTLAND, OR2023

    MEDICAL RESEARCH