researchers and scientific communityconference attendees (academics, clinicians, researchers)people living with Alzheimer's disease (indirect/ultimate beneficiaries)
About Alzheimer'S Drug Discovery Foundation
Alzheimer's Drug Discovery Foundation focuses on speeding up drug development for Alzheimer’s disease, with a grantmaking model built around translational research rather than broad general support. Its recent awards show a strong emphasis on companies and research institutions working on diagnostics, biomarkers, prevention, and early-stage therapeutics. The largest listed grant went to Alamar Biosciences for Alzheimer’s research, and other major awards supported C2N Diagnostics and Curasen Therapeutics Inc. Across the recent-grants list, the foundation backs work that moves from discovery into validation, including biomarker development, clinical-trial enabling research, and therapeutic pipelines. That pattern fits the foundation’s stated priorities in biomarkers, clinical trials, prevention, neuroinflammation, tau, amyloid-related research, and aging biology. Recent recipients also include institutions such as The Scripps Research Institute and Cleveland Clinic Foundation, showing support for both academic and industry-led research. The grantmaking style is highly targeted, with large awards aimed at specific scientific milestones in Alzheimer’s and related dementias.
What Alzheimer'S Drug Discovery Foundation Funds
A major part of the foundation’s portfolio centers on biomarker science. It gave $5,609,700 to Pharmatrophix for Alzheimer’s research, and it also supports biomarker development programs for neuroimaging and cerebrospinal fluid work. Prevention is another clear theme: the foundation awarded $3,247,762 to University of Nevada Las Vegas for Alzheimer’s research, alongside a prevention-focused funding stream for clinical trials, comparative effectiveness research, and epidemiological studies. Therapeutic development also features prominently. It gave $5,000,000 to Coya Therapeutics for Alzheimer’s research and $4,845,794 to Modulo Bio Inc for Alzheimer’s research, reflecting support for translational programs that move toward early-stage clinical testing. The foundation also funds research dissemination and scientific community-building through prize and conference-related programs.
How Alzheimer'S Drug Discovery Foundation Gives
Typical awards are large: the 25th percentile is $213,088, the median is $600,000, and the 75th percentile is $1,822,405. The recent-grants list shows repeat funding to the same recipient in different years, including Davos Alzheimers Collaborative in both 2024 and 2025, which points to ongoing project support rather than one-time awards only. The foundation is a regular funder, not a fund for individuals, and it does not make program-related investments. Its active programs include several unsolicited RFPs, especially in therapeutics, prevention, and biomarker development, alongside a prize program that is invitation- or selection-based rather than open application.
Financial Snapshot
Annual Giving
$54.8M
Total Assets
$299.4M
Total Revenue
$47.3M
Total Expenses
$88.3M
Typical Grant Size
Most grants fall between $213K and $1.8M, with a median of $600K.
25th Percentile
$213K
Median
$600K
75th Percentile
$1.8M
Geographic Reach
National14 states funded
About 5% of grants go to recipients in CT.
Funding intensity
LowHigh
Headquarters
Leadership
HOWARD FILLIT MD
Accepts unsolicited proposals
Deep Analysis
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conference sponsorshipresearch-focused fundingtargeted/project supportcapacity building for scientific community
Topics
Alzheimer's disease researchdementia researchscientific conference supportresearch dissemination and networking
Where Alzheimer'S Drug Discovery Foundation Makes Grants
Grantmaking is national, and every recipient in the provided country distribution is in the United States. The top state by grant count is Connecticut, while only 4% of grants go to recipients in the foundation’s headquarters state of New York. Recent awards are spread across major research hubs, including Cambridge, Boston, San Diego, and Philadelphia. California appears frequently through recipients in Fremont, San Carlos, Menlo Park, San Francisco, and La Jolla, showing a strong West Coast concentration alongside East Coast research centers.
Frequently Asked Questions About Alzheimer'S Drug Discovery Foundation
What kinds of research does Alzheimer's Drug Discovery Foundation support?
The foundation focuses on Alzheimer’s disease drug discovery and development, with support for biomarkers, clinical trials, prevention, neuroinflammation, tau, amyloid-related research, and aging biology. Its active programs also include neuroimaging and CSF biomarker RFPs, drug development RFPs, and prevention-focused funding for clinical trials and epidemiological studies.
Does Alzheimer's Drug Discovery Foundation accept unsolicited proposals?
Yes, several active programs accept unsolicited applications. That includes the Neuroimaging and CSF Biomarker RFP, the Prevention RFP, and the Drug Development RFP, each listed as accepting unsolicited submissions. The prize and biobank-sharing programs are not open to unsolicited applications.
What is the typical grant size?
Typical grants are substantial: the 25th percentile is $213,088, the median is $600,000, and the 75th percentile is $1,822,405. Active program ranges also reach from $100,000 to $3,000,000 for therapeutics and biomarker RFPs.
Are grants repeated to the same recipient over time?
Yes. Davos Alzheimers Collaborative appears twice in the recent-grants list, with awards of $2,500,000 in both 2024 and 2025. That suggests the foundation supports some recipients across multiple years.
Who receives the funding?
The recent-grants list shows funding to academic centers, biotechnology companies, and research institutions. Examples include The Scripps Research Institute, Cleveland Clinic Foundation, and University of Nevada Las Vegas, alongside companies working on Alzheimer’s research and diagnostics.
Latest 990 Filing
2025
Source: IRS Form 990-PF, fiscal year 2025.
Recent Grants
Most recent grants reported to the IRS.
Recipient
Location
Amount
Year
Purpose
ALAMAR BIOSCIENCES
FREMONT, CA
$10,016,094
2025
ALZHEIMERS RESEARCH
C2N DIAGNOSTICS
ST LOUIS, MO
$7,025,121
2025
ALZHEIMERS RESEARCH
PHARMATROPHIX
MENLO PARK, CA
$5,609,700
2025
ALZHEIMERS RESEARCH
METRO INTERNATIONAL BIOTECHEDENROC
CAMBRIDGE, MA
$5,000,000
2025
ALZHEIMERS RESEARCH
COYA THERAPEUTICS
HOUSTON, TX
$5,000,000
2025
ALZHEIMERS RESEARCH
MODULO BIO INC
SAN DIEGO, CA
$4,845,794
2025
ALZHEIMERS RESEARCH
UNIVERSITY OF NEVADA LAS VEGAS
LAS VEGAS, NV
$3,247,762
2025
ALZHEIMERS RESEARCH
AQUINNAH PHARMACEUTICALS
CAMBRIDGE, MA
$2,999,586
2025
ALZHEIMERS RESEARCH
DAVOS ALZHEIMERS COLLABORATIVE
PHILADELPHIA, PA
$2,500,000
2025
ALZHEIMERS RESEARCH
UNIVERSITY OF ARIZONA - HEALTH SCIENCES
TUCSON, AZ
$1,774,201
2025
ALZHEIMERS RESEARCH
VACCINEX
ROCHESTER, NY
$1,750,000
2025
ALZHEIMERS RESEARCH
VIEWMIND
NEW YORK, NY
$1,429,119
2025
ALZHEIMERS RESEARCH
ESYA INC
FRISCO, TX
$789,000
2025
ALZHEIMERS RESEARCH
TRUSTEES OF INDIANA UNIVERSITY
BLOOMINGTON, IN
$599,920
2025
ALZHEIMERS RESEARCH
UNIVERSITY OF MINNESOTA
BROOKLINE, MA
$493,875
2025
ALZHEIMERS RESEARCH
CLEARVIEW HEALTHCARE PARTNERS
NEW YORK, NY
$272,000
2025
ALZHEIMERS RESEARCH
JOHNS HOPKINS UNIVERSITY
BALTIMORE, MD
$269,967
2025
ALZHEIMERS RESEARCH
UNIVERSITY OF KANSAS MEDICAL CENTER
KANSAS CITY, KS
$250,000
2025
ALZHEIMERS RESEARCH
NEUROTHERAPIA INC
GATES MILLS, OH
$250,000
2025
ALZHEIMERS RESEARCH
NEUROAGE THERAPEUTICS
SAN FRANCISCO, CA
$249,817
2025
ALZHEIMERS RESEARCH
MTI BIOTECH INC
AMES, IA
$158,576
2025
ALZHEIMERS RESEARCH
TRUSTEES OF BOSTON UNIVERSITY
BOSTON, MA
$150,000
2025
ALZHEIMERS RESEARCH
USAGAINSTALZHEIMER'S NETWORK
WASHINGTON, DC
$65,000
2025
ALZHEIMERS RESEARCH
THE MILKEN INSTITUTE
NEW YORK, NY
$25,000
2025
ALZHEIMERS RESEARCH
GLOBAL ALZHEIMER'S PLATFORM FOUNDATION
WASHINGTON, DC
$20,000
2025
ALZHEIMERS RESEARCH
MOBILITY CONSULTING GROUP LLC
ALPHARETTA, GA
$9,992
2025
ALZHEIMERS RESEARCH
CURASEN THERAPEUTICS INC
SAN CARLOS, CA
$5,814,712
2024
ALZHEIMERS RESEARCH
METRO INTERNATIONAL BIOTECH
CAMBRIDGE, MA
$5,750,000
2024
ALZHEIMERS RESEARCH
THERINI BIO
SAN FRANCISCO, CA
$5,000,000
2024
ALZHEIMERS RESEARCH
APRINOIA THERAPEUTICS INC
CAMBRIDGE, MA
$4,357,900
2024
ALZHEIMERS RESEARCH
DAVOS ALZHEIMERS COLLABORATIVE
PHILADELPHIA, PA
$2,500,000
2024
ALZHEIMERS RESEARCH
ALZPATH INC
CARLSBAD, CA
$1,910,202
2024
ALZHEIMERS RESEARCH
CLEVELAND CLINIC FOUNDATION
CLEVELAND, OH
$1,828,343
2024
ALZHEIMERS RESEARCH
ASTROCYTE PHARMACEUTICALS INC
GROTON, CT
$1,000,000
2024
ALZHEIMERS RESEARCH
STARTUP HEALTH LLC
NEW YORK, NY
$975,875
2024
ALZHEIMERS RESEARCH
TRUSTEES OF BOSTON UNIVERSITY
BOSTON, MA
$844,286
2024
ALZHEIMERS RESEARCH
NEURODEX
NATICK, MA
$750,000
2024
ALZHEIMERS RESEARCH
CICARDIC LLC
ARLINGTON, MA
$675,890
2024
ALZHEIMERS RESEARCH
VIRGINIA COMMONWEALTH UNIVERSITY
RICHMOND, VA
$600,000
2024
ALZHEIMERS RESEARCH
TUFTS MEDICAL CENTER
BOSTON, MA
$599,788
2024
ALZHEIMERS RESEARCH
CASE WESTERN RESERVE UNIVERSITY
CLEVELAND, OH
$599,259
2024
ALZHEIMERS RESEARCH
WAKE FOREST UNIVERSITY
WINSTON SALEM, NC
$589,379
2024
ALZHEIMERS RESEARCH
AMPRION INC
SAN FRANCISCO, CA
$570,750
2024
ALZHEIMERS RESEARCH
BRAINSCOPE COMPANY INC
BETHESDA, MD
$491,086
2024
ALZHEIMERS RESEARCH
MILKEN INSTITUTE
AMES, IA
$250,000
2024
CONFERENCE SPONSORSHIP
PELAGOS PHARMACEUTICALS
CAMBRIDGE, MA
$214,118
2024
ALZHEIMERS RESEARCH
UNIVERSITY OF CALIFORNIA IRVINE
IRVINE, CA
$175,000
2024
ALZHEIMERS RESEARCH
BIOTECHNOLOGY INNOVATION ORGANIZATION
WASHINGTON, DC
$73,700
2024
ALZHEIMERS RESEARCH
USAGAINSTALZHEIMER'S
WASHINGTON, DC
$35,000
2024
ALZHEIMERS RESEARCH
FOUNDATION FOR THE NATIONAL INSTITUTE OF HEALTH
NORTH BETHESDA, MD
$30,000
2024
ALZHEIMERS RESEARCH
ALAMAR BIOSCIENCES
$10,016,094
FREMONT, CA2025
ALZHEIMERS RESEARCH
C2N DIAGNOSTICS
$7,025,121
ST LOUIS, MO2025
ALZHEIMERS RESEARCH
PHARMATROPHIX
$5,609,700
MENLO PARK, CA2025
ALZHEIMERS RESEARCH
METRO INTERNATIONAL BIOTECHEDENROC
$5,000,000
CAMBRIDGE, MA2025
ALZHEIMERS RESEARCH
COYA THERAPEUTICS
$5,000,000
HOUSTON, TX2025
ALZHEIMERS RESEARCH
MODULO BIO INC
$4,845,794
SAN DIEGO, CA2025
ALZHEIMERS RESEARCH
UNIVERSITY OF NEVADA LAS VEGAS
$3,247,762
LAS VEGAS, NV2025
ALZHEIMERS RESEARCH
AQUINNAH PHARMACEUTICALS
$2,999,586
CAMBRIDGE, MA2025
ALZHEIMERS RESEARCH
DAVOS ALZHEIMERS COLLABORATIVE
$2,500,000
PHILADELPHIA, PA2025
ALZHEIMERS RESEARCH
UNIVERSITY OF ARIZONA - HEALTH SCIENCES
$1,774,201
TUCSON, AZ2025
ALZHEIMERS RESEARCH
VACCINEX
$1,750,000
ROCHESTER, NY2025
ALZHEIMERS RESEARCH
VIEWMIND
$1,429,119
NEW YORK, NY2025
ALZHEIMERS RESEARCH
ESYA INC
$789,000
FRISCO, TX2025
ALZHEIMERS RESEARCH
TRUSTEES OF INDIANA UNIVERSITY
$599,920
BLOOMINGTON, IN2025
ALZHEIMERS RESEARCH
UNIVERSITY OF MINNESOTA
$493,875
BROOKLINE, MA2025
ALZHEIMERS RESEARCH
CLEARVIEW HEALTHCARE PARTNERS
$272,000
NEW YORK, NY2025
ALZHEIMERS RESEARCH
JOHNS HOPKINS UNIVERSITY
$269,967
BALTIMORE, MD2025
ALZHEIMERS RESEARCH
UNIVERSITY OF KANSAS MEDICAL CENTER
$250,000
KANSAS CITY, KS2025
ALZHEIMERS RESEARCH
NEUROTHERAPIA INC
$250,000
GATES MILLS, OH2025
ALZHEIMERS RESEARCH
NEUROAGE THERAPEUTICS
$249,817
SAN FRANCISCO, CA2025
ALZHEIMERS RESEARCH
MTI BIOTECH INC
$158,576
AMES, IA2025
ALZHEIMERS RESEARCH
TRUSTEES OF BOSTON UNIVERSITY
$150,000
BOSTON, MA2025
ALZHEIMERS RESEARCH
USAGAINSTALZHEIMER'S NETWORK
$65,000
WASHINGTON, DC2025
ALZHEIMERS RESEARCH
THE MILKEN INSTITUTE
$25,000
NEW YORK, NY2025
ALZHEIMERS RESEARCH
GLOBAL ALZHEIMER'S PLATFORM FOUNDATION
$20,000
WASHINGTON, DC2025
ALZHEIMERS RESEARCH
MOBILITY CONSULTING GROUP LLC
$9,992
ALPHARETTA, GA2025
ALZHEIMERS RESEARCH
CURASEN THERAPEUTICS INC
$5,814,712
SAN CARLOS, CA2024
ALZHEIMERS RESEARCH
METRO INTERNATIONAL BIOTECH
$5,750,000
CAMBRIDGE, MA2024
ALZHEIMERS RESEARCH
THERINI BIO
$5,000,000
SAN FRANCISCO, CA2024
ALZHEIMERS RESEARCH
APRINOIA THERAPEUTICS INC
$4,357,900
CAMBRIDGE, MA2024
ALZHEIMERS RESEARCH
DAVOS ALZHEIMERS COLLABORATIVE
$2,500,000
PHILADELPHIA, PA2024
ALZHEIMERS RESEARCH
ALZPATH INC
$1,910,202
CARLSBAD, CA2024
ALZHEIMERS RESEARCH
CLEVELAND CLINIC FOUNDATION
$1,828,343
CLEVELAND, OH2024
ALZHEIMERS RESEARCH
ASTROCYTE PHARMACEUTICALS INC
$1,000,000
GROTON, CT2024
ALZHEIMERS RESEARCH
STARTUP HEALTH LLC
$975,875
NEW YORK, NY2024
ALZHEIMERS RESEARCH
TRUSTEES OF BOSTON UNIVERSITY
$844,286
BOSTON, MA2024
ALZHEIMERS RESEARCH
NEURODEX
$750,000
NATICK, MA2024
ALZHEIMERS RESEARCH
CICARDIC LLC
$675,890
ARLINGTON, MA2024
ALZHEIMERS RESEARCH
VIRGINIA COMMONWEALTH UNIVERSITY
$600,000
RICHMOND, VA2024
ALZHEIMERS RESEARCH
TUFTS MEDICAL CENTER
$599,788
BOSTON, MA2024
ALZHEIMERS RESEARCH
CASE WESTERN RESERVE UNIVERSITY
$599,259
CLEVELAND, OH2024
ALZHEIMERS RESEARCH
WAKE FOREST UNIVERSITY
$589,379
WINSTON SALEM, NC2024
ALZHEIMERS RESEARCH
AMPRION INC
$570,750
SAN FRANCISCO, CA2024
ALZHEIMERS RESEARCH
BRAINSCOPE COMPANY INC
$491,086
BETHESDA, MD2024
ALZHEIMERS RESEARCH
MILKEN INSTITUTE
$250,000
AMES, IA2024
CONFERENCE SPONSORSHIP
PELAGOS PHARMACEUTICALS
$214,118
CAMBRIDGE, MA2024
ALZHEIMERS RESEARCH
UNIVERSITY OF CALIFORNIA IRVINE
$175,000
IRVINE, CA2024
ALZHEIMERS RESEARCH
BIOTECHNOLOGY INNOVATION ORGANIZATION
$73,700
WASHINGTON, DC2024
ALZHEIMERS RESEARCH
USAGAINSTALZHEIMER'S
$35,000
WASHINGTON, DC2024
ALZHEIMERS RESEARCH
FOUNDATION FOR THE NATIONAL INSTITUTE OF HEALTH
$30,000
NORTH BETHESDA, MD2024
ALZHEIMERS RESEARCH
Open Grant Opportunities
Current and upcoming funding from Alzheimer'S Drug Discovery Foundation that your nonprofit may be able to apply for.
Open nowCloses Aug 17, 2026Award: Up to $600K
ADDF-Harrington Scholar Program
drug discoverytranslational researchtherapeutics+1 more
Who can apply: Eligibility details were not provided in the scraped content. The program appears to be an application-based partner funding opportunity.
Deadline: Full proposal due August 17, 2026; LOI deadline has passed.
IND-enabling studiesEarly-stage clinical trialsDrug repurposing+4 more
Who can apply: Academic centers and biotechnology companies worldwide advancing therapeutic and biomarker development for Alzheimer’s and related dementias; terms vary by RFP and use mission-related investments (returns expected for some awards).
Deadline: Letter of Intent: 2026-09-14 (5:00 pm ET). Invited Full Proposal: TBD
Drug Development RFP (Therapeutics Funding Programs)
drug developmentIND-enabling studiesearly-stage clinical trials+2 more
Who can apply: Academic centers and biotechs worldwide advancing therapeutic development for Alzheimer's and related dementias; funding is milestone-based mission-related investment.
Deadline: Applications are reviewed throughout the year; current opening noted on funding opportunities page with LOI due September 14, 2026 for therapeutic programs
Neuroimaging and CSF Biomarker RFP (Therapeutics Funding Programs - Biomarkers)
biomarkersneuroimagingCSF biomarkers+2 more
Who can apply: Open to academic institutions and biotechnology companies worldwide working on biomarker development for Alzheimer's disease and related dementias. Funding is through ADDF mission-related investments tied to milestones.
Deadline: Letter of Intent due September 14, 2026; invited full proposal TBD.
Who can apply: Open to academic institutions and biotechnology companies worldwide pursuing prevention-oriented programs for Alzheimer's disease and related dementias. Awards are mission-related investments with milestone-based terms.
Deadline: Letter of Intent due September 14, 2026; invited full proposal TBD.
drug developmenttherapeuticsneuroimaging biomarkers+4 more
Who can apply: Open to academic centers and biotechs advancing therapeutic and biomarker development for Alzheimer's and related dementias. Specific eligibility varies by RFP.
Deadline: Letter of Intent: September 14, 2026; Invited Full Proposal: TBD
Deadlines and eligibility are summarized from public sources and may change — always confirm the details on the funder's official application page before applying.