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    5. Bioindustrial Manufacturing and Design Ecosystem
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    Bioindustrial Manufacturing and Design Ecosystem

    ActiveCommunity Improvement
    EMERYVILLE, CAWebsite6518676588

    About Bioindustrial Manufacturing and Design Ecosystem

    BioMADE’s mission is to enable domestic bioindustrial manufacturing at all scales, develop technologies to enhance U.S. bioindustrial competitiveness, de-risk investment in relevant infrastructure, and expand the biomanufacturing workforce to realize the economic promise of industrial biotechnology.

    Focus Areas

    bioindustrial manufacturingtechnology scale-up and commercializationpilot-to-demonstration plant infrastructureworkforce training and educationbiosecurity and safetysustainable materials and chemicalsdefense-relevant manufacturing

    Who They Fund

    biomanufacturing workforce and trainees (students, technicians)regional manufacturing hubs and local ecosystems (e.g., Worcester, San Francisco Bay Area)vaccine manufacturers and diagnostic producers

    About Bioindustrial Manufacturing and Design Ecosystem

    Bioindustrial Manufacturing and Design Ecosystem Inc backs the kinds of projects that move bioindustrial manufacturing from research into production. Its largest recent grant, $7.8 million to Cleanjoule in Salt Lake City, was for biomanufacturing research, and the foundation has also made repeated large awards to Amyris Inc in Emeryville and Cambium Biomaterials Inc in Mojave. That pattern points to a funder supporting companies and institutions working on scale-up, process development, and commercialization rather than isolated pilot efforts. The grant list includes industrial biotechnology firms, universities, and applied research organizations, alongside awards tied to education and workforce development. Across the recent grants file, the foundation supports domestic biomanufacturing infrastructure, technology optimization, and related workforce capacity. It also appears to invest in organizations working on sustainable materials, bio-based chemicals, and defense-relevant manufacturing. The recipients include research-heavy partners such as Ginkgo Bioworks, Mitre Corporation, and the University of California system, indicating a mix of industry, academic, and mission-driven applied research recipients. The overall picture is of a funder using sizable grants to advance U.S. biomanufacturing capability at multiple stages of the pipeline.

    What Bioindustrial Manufacturing and Design Ecosystem Funds

    A core theme is biomanufacturing research and scale-up. The foundation gave $2.17 million to Genomatica Inc in San Diego for biomanufacturing research, and $1.41 million to Ginkgo Bioworks Inc in Boston for the same purpose. Another recurring area is bio-based materials and chemicals: it awarded $796,686 to Lygos Inc in Berkeley and $689,118 to Origin Materials in West Sacramento, both under biomanufacturing research. Workforce development is also part of the portfolio. The Regents of University of California Davis received $1.19 million for education and workforce development research and service delivery, and East Tennessee State University received $546,579 for the same category. Applied infrastructure and translational work show up as well, with awards to universities and engineering-oriented entities that support the broader biomanufacturing ecosystem.

    How Bioindustrial Manufacturing and Design Ecosystem Gives

    Grant size is wide, with a p25 of $39,241, a median grant of $112,241, and a p75 of $329,372. The recent file shows both very large research awards and a long tail of smaller amounts, suggesting a portfolio that mixes platform-scale commitments with narrower project support. Recipients appear across 2024 and 2025, including repeated awards to the same organizations in successive years, which points to ongoing relationships rather than one-off grants. The organization funds only institutions and companies, not individuals, and it does not make program-related investments. The pattern is also strongly domestic: all listed recipients are in the United States.

    Financial Snapshot

    Annual Giving

    $42.3M

    Total Assets

    $37.6M

    Total Revenue

    $65.1M

    Total Expenses

    $68M

    Typical Grant Size

    Most grants fall between $39K and $329K, with a median of $112K.

    25th Percentile

    $39K

    Median

    $112K

    75th Percentile

    $329K

    Geographic Reach

    National28 states funded

    About 35% of grants go to recipients in CA.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

    DOUGLAS FRIEDMAN

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    EIN: 85-1800999
    3 filings on record
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    industrial biotechnology companies and scale-up teams
    agriculture/aquaculture producers (e.g., poultry industry using probiotic feed additives)

    Funding Style

    applied research and developmentcapacity building / workforce trainingtranslational / de-risking of technologiesregional partnership and distributed manufacturing support

    Topics

    biomanufacturing process scale-up and fermentation kineticsdevelopment of domestic supply chains for vaccines and antigensbio-based materials and novel polymer productionstrain engineering and scalable AI-assisted optimizationsafety, security, sustainability, and social responsibility in biotechdistributed and decentralized manufacturing for diagnostics and therapeuticseducation programs and bioreactor training for workforce development

    Where Bioindustrial Manufacturing and Design Ecosystem Makes Grants

    Grantmaking is national, with 165 grants to U.S. recipients. California is the top state by grant count and also accounts for 35% of grants. Recent recipients cluster in California cities including Emeryville, Mojave, San Diego, Berkeley, Davis, Alameda, and West Sacramento. Other notable recipient locations include Salt Lake City, McLean, Boston, Alexandria, Ames, Philadelphia, Urbana, and Johnson City, showing a spread across university, company, and research hubs.

    Frequently Asked Questions About Bioindustrial Manufacturing and Design Ecosystem

    What does Bioindustrial Manufacturing and Design Ecosystem Inc primarily fund?

    The recent grants focus on biomanufacturing research, technology scale-up, and related workforce development. Named grants include support for biomanufacturing research at companies and universities, plus awards for education and workforce development research and service delivery.

    What is a typical grant size from this foundation?

    The grant-size distribution is $39,241 at the 25th percentile, $112,241 at the median, and $329,372 at the 75th percentile. The file also includes several multimillion-dollar awards, including a $7.8 million grant to Cleanjoule.

    Does the foundation fund organizations outside California?

    Yes. Although California is the top state by grant count, the recent grants also go to organizations in Utah, Virginia, Massachusetts, Iowa, Pennsylvania, Illinois, Tennessee, and New York. All listed recipients are in the United States.

    Does Bioindustrial Manufacturing and Design Ecosystem Inc support workforce development?

    Yes. Two recent awards are explicitly categorized as education and workforce development research and service delivery: $1.19 million to The Regents of University of California Davis and $546,579 to East Tennessee State University.

    Does the foundation give recurring grants to the same organizations?

    Yes. The recent grants list shows repeat awards across 2024 and 2025 to organizations such as Amyris Inc, Cambium Biomaterials Inc, Mitre Corporation, Genomatica Inc, and The Regents of University of California Berkeley.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    Open Grant Opportunities

    Current and upcoming funding from Bioindustrial Manufacturing and Design Ecosystem that your nonprofit may be able to apply for.

    Open nowRolling / open intake

    BioMADE Project Calls (Member Project Funding)

    Bioindustrial manufacturingTechnology and innovationWorkforce development+2 more

    Who can apply: BioMADE states that projects must contribute to building a sustainable, domestic, end-to-end bioindustrial manufacturing ecosystem. Member organizations have priority access to project calls, and BioMADE notes that it may issue open requests for proposals and topic-specific project calls based on available funding.

    Deadline: Deadlines vary by Project Call. Historically BioMADE has used a staged process (White Paper deadlines, then invitation to Full Proposal with separate deadline). Specific dates are published for each call on the Project Calls page and associated news/events pages.

    View & apply

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    Deadlines and eligibility are summarized from public sources and may change — always confirm the details on the funder's official application page before applying.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    CLEANJOULESALT LAKE CITY, UT$7,837,3232025BIOMANUFACTURING RESEARCH
    AMYRIS INCEMERYVILLE, CA$6,967,5352025BIOMANUFACTURING RESEARCH
    CAMBIUM BIOMATERIALS INCMOJAVE, CA$4,911,0502025BIOMANUFACTURING RESEARCH
    MITRE CORPORATIONMCLEAN, VA$3,073,7012025BIOMANUFACTURING RESEARCH
    FARMED MATERIALSNEWTON CENTER, MA$2,578,2512025BIOMANUFACTURING RESEARCH
    GENOMATICA INCSAN DIEGO, CA$2,172,5672025BIOMANUFACTURING RESEARCH
    GINKGO BIOWORKS INCBOSTON, MA$1,409,6372025BIOMANUFACTURING RESEARCH
    THE REGENTS OF UNIVERSITY OF CALIFORNIA UC DAVISDAVIS, CA$1,189,3092025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    THE REGENTS OF UNIVERSITY OF CALIFORNIA BERKELEYBERKELEY, CA$1,187,7882025BIOMANUFACTURING RESEARCH
    INDUSTRIAL MICROBESALAMEDA, CA$941,9112025BIOMANUFACTURING RESEARCH
    CAPRA BIOSCIENCES INCALEXANDRIA, VA$862,1512025BIOMANUFACTURING RESEARCH
    IOWA STATE UNIVERSITYAMES, IA$807,1622025BIOMANUFACTURING RESEARCH
    LYGOS INCBERKELEY, CA$796,6862025BIOMANUFACTURING RESEARCH
    ZERO ACRE FARMSDAVIS, CA$733,2082025BIOMANUFACTURING RESEARCH
    ORIGIN MATERIALSWEST SACRAMENTO, CA$689,1182025BIOMANUFACTURING RESEARCH
    UNIVERSITY OF ILLINOISURBANA, IL$551,2182025BIOMANUFACTURING RESEARCH
    EAST TENNESSEE STATE UNIVERSITYJOHNSON CITY, TN$546,5792025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    BOSTON UNIVERSITYNEW YORK, NY$527,5512025BIOMANUFACTURING RESEARCH
    NORTH CAROLINA STATE UNIVERSITY - RALEIGHRALEIGH, NC$380,3992025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    SUDHIN BIOPHARMA COSUPERIOR, CO$331,8932025BIOMANUFACTURING RESEARCH
    CITRINE INFORMATICSREDWOOD CITY, CA$297,3552025BIOMANUFACTURING RESEARCH
    TANDEM REPEAT TECHNOLOGY INCPHILADELPHIA, PA$271,8142025RESEARCH IN SAFETY, SECURITY, SUSTAINABILITY, AND SOCIAL RESPONSIBILITY
    UNIVERSITY OF DELAWARENEWARK, DE$264,0842025BIOMANUFACTURING RESEARCH
    GRASPXRST PETERSBURG, FL$258,1292025BIOMANUFACTURING RESEARCH
    UTAH STEM FOUNDATIONSOUTH SALT LAKE CITY, UT$227,3962025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    GENERAL PROBIOTICS INCSAINT PAUL, MN$223,1462025BIOMANUFACTURING RESEARCH
    CHECKERSPOT INCALAMEDA, CA$196,5762025BIOMANUFACTURING RESEARCH
    BIOBUILDER EDUCATIONAL FOUNDATIONNEWTON CENTER, MN$188,1502025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    THE UNIVERSITY OF TEXAS - AUSTINAUSTIN, TX$168,5912025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    REGENTS UNIVERSITY OF MINNESOTAMINNEAPOLIS, MN$154,3972025BIOMANUFACTURING RESEARCH
    MANGO MATERIALSOAKLAND, CA$128,7222025BIOMANUFACTURING RESEARCH
    XPERIENCE SCIENCEBEL AIR, MD$121,6782025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    SUPERBREWED FOOD INCCASTLE, DE$120,5812025BIOMANUFACTURING RESEARCH
    BINGHAMTON UNIVERSITYBINGHAMTON, NY$112,2412025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    KULTEVATCREVE COEUR, MO$112,0482025BIOMANUFACTURING RESEARCH
    MANUS BIOWALTHAM, ME$102,0642025BIOMANUFACTURING RESEARCH
    UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INCATHENS, GA$93,9272025RESEARCH IN SAFETY, SECURITY, SUSTAINABILITY, AND SOCIAL RESPONSIBILITY
    UNIVERSITY OF HAWAII - HILOHONOLULU, HI$85,6182025BIOMANUFACTURING RESEARCH
    VALERIAN MATERIALSST LOUISE PARK, MN$84,1762025BIOMANUFACTURING RESEARCH
    EXOZYMES INC (FORMERLY INVIZYNE TECHNOLOGIES)MONOROVIA, CA$79,9832025BIOMANUFACTURING RESEARCH
    PARADIGM GROWTHAPPLE VALLEY, MN$57,7502025BIOMANUFACTURING RESEARCH
    IDEACHEMRAPID CITY, SD$51,8552025BIOMANUFACTURING RESEARCH
    NORTH CAROLINA A&T STATE UNIVERSITYGREENSBORO, NC$50,0002025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    FINGER LAKES COMMUNITY COLLEGECANANDAIGUA, NY$50,0002025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    THE UNIVERSITY OF KANSAS CENTER FOR RESEARCH INCLAWRENCE, KS$50,0002025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    THE OHIO STATE UNIVERSITYCOLUMBUS, OH$50,0002025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    UNIVERSITY OF CONNECTICUT AT STORRSSTORRS MANSFIELD, CT$50,0002025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY
    TEGA THERAPEUTICS INCSAN DIEGO, CA$44,8272025BIOMANUFACTURING RESEARCH
    SOUTHERN ILLINOIS UNIVERSITY - EDWARDSVILLENEW YORK, NY$39,2412025BIOMANUFACTURING RESEARCH
    SIGNATURE SCIENCE LLCAUSTIN, TX$24,7532025EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    CLEANJOULE

    $7,837,323
    SALT LAKE CITY, UT2025

    BIOMANUFACTURING RESEARCH

    AMYRIS INC

    $6,967,535
    EMERYVILLE, CA2025

    BIOMANUFACTURING RESEARCH

    CAMBIUM BIOMATERIALS INC

    $4,911,050
    MOJAVE, CA2025

    BIOMANUFACTURING RESEARCH

    MITRE CORPORATION

    $3,073,701
    MCLEAN, VA2025

    BIOMANUFACTURING RESEARCH

    FARMED MATERIALS

    $2,578,251
    NEWTON CENTER, MA2025

    BIOMANUFACTURING RESEARCH

    GENOMATICA INC

    $2,172,567
    SAN DIEGO, CA2025

    BIOMANUFACTURING RESEARCH

    GINKGO BIOWORKS INC

    $1,409,637
    BOSTON, MA2025

    BIOMANUFACTURING RESEARCH

    THE REGENTS OF UNIVERSITY OF CALIFORNIA UC DAVIS

    $1,189,309
    DAVIS, CA2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    THE REGENTS OF UNIVERSITY OF CALIFORNIA BERKELEY

    $1,187,788
    BERKELEY, CA2025

    BIOMANUFACTURING RESEARCH

    INDUSTRIAL MICROBES

    $941,911
    ALAMEDA, CA2025

    BIOMANUFACTURING RESEARCH

    CAPRA BIOSCIENCES INC

    $862,151
    ALEXANDRIA, VA2025

    BIOMANUFACTURING RESEARCH

    IOWA STATE UNIVERSITY

    $807,162
    AMES, IA2025

    BIOMANUFACTURING RESEARCH

    LYGOS INC

    $796,686
    BERKELEY, CA2025

    BIOMANUFACTURING RESEARCH

    ZERO ACRE FARMS

    $733,208
    DAVIS, CA2025

    BIOMANUFACTURING RESEARCH

    ORIGIN MATERIALS

    $689,118
    WEST SACRAMENTO, CA2025

    BIOMANUFACTURING RESEARCH

    UNIVERSITY OF ILLINOIS

    $551,218
    URBANA, IL2025

    BIOMANUFACTURING RESEARCH

    EAST TENNESSEE STATE UNIVERSITY

    $546,579
    JOHNSON CITY, TN2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    BOSTON UNIVERSITY

    $527,551
    NEW YORK, NY2025

    BIOMANUFACTURING RESEARCH

    NORTH CAROLINA STATE UNIVERSITY - RALEIGH

    $380,399
    RALEIGH, NC2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    SUDHIN BIOPHARMA CO

    $331,893
    SUPERIOR, CO2025

    BIOMANUFACTURING RESEARCH

    CITRINE INFORMATICS

    $297,355
    REDWOOD CITY, CA2025

    BIOMANUFACTURING RESEARCH

    TANDEM REPEAT TECHNOLOGY INC

    $271,814
    PHILADELPHIA, PA2025

    RESEARCH IN SAFETY, SECURITY, SUSTAINABILITY, AND SOCIAL RESPONSIBILITY

    UNIVERSITY OF DELAWARE

    $264,084
    NEWARK, DE2025

    BIOMANUFACTURING RESEARCH

    GRASPXR

    $258,129
    ST PETERSBURG, FL2025

    BIOMANUFACTURING RESEARCH

    UTAH STEM FOUNDATION

    $227,396
    SOUTH SALT LAKE CITY, UT2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    GENERAL PROBIOTICS INC

    $223,146
    SAINT PAUL, MN2025

    BIOMANUFACTURING RESEARCH

    CHECKERSPOT INC

    $196,576
    ALAMEDA, CA2025

    BIOMANUFACTURING RESEARCH

    BIOBUILDER EDUCATIONAL FOUNDATION

    $188,150
    NEWTON CENTER, MN2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    THE UNIVERSITY OF TEXAS - AUSTIN

    $168,591
    AUSTIN, TX2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    REGENTS UNIVERSITY OF MINNESOTA

    $154,397
    MINNEAPOLIS, MN2025

    BIOMANUFACTURING RESEARCH

    MANGO MATERIALS

    $128,722
    OAKLAND, CA2025

    BIOMANUFACTURING RESEARCH

    XPERIENCE SCIENCE

    $121,678
    BEL AIR, MD2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    SUPERBREWED FOOD INC

    $120,581
    CASTLE, DE2025

    BIOMANUFACTURING RESEARCH

    BINGHAMTON UNIVERSITY

    $112,241
    BINGHAMTON, NY2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    KULTEVAT

    $112,048
    CREVE COEUR, MO2025

    BIOMANUFACTURING RESEARCH

    MANUS BIO

    $102,064
    WALTHAM, ME2025

    BIOMANUFACTURING RESEARCH

    UNIVERSITY OF GEORGIA RESEARCH FOUNDATION INC

    $93,927
    ATHENS, GA2025

    RESEARCH IN SAFETY, SECURITY, SUSTAINABILITY, AND SOCIAL RESPONSIBILITY

    UNIVERSITY OF HAWAII - HILO

    $85,618
    HONOLULU, HI2025

    BIOMANUFACTURING RESEARCH

    VALERIAN MATERIALS

    $84,176
    ST LOUISE PARK, MN2025

    BIOMANUFACTURING RESEARCH

    EXOZYMES INC (FORMERLY INVIZYNE TECHNOLOGIES)

    $79,983
    MONOROVIA, CA2025

    BIOMANUFACTURING RESEARCH

    PARADIGM GROWTH

    $57,750
    APPLE VALLEY, MN2025

    BIOMANUFACTURING RESEARCH

    IDEACHEM

    $51,855
    RAPID CITY, SD2025

    BIOMANUFACTURING RESEARCH

    NORTH CAROLINA A&T STATE UNIVERSITY

    $50,000
    GREENSBORO, NC2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    FINGER LAKES COMMUNITY COLLEGE

    $50,000
    CANANDAIGUA, NY2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    THE UNIVERSITY OF KANSAS CENTER FOR RESEARCH INC

    $50,000
    LAWRENCE, KS2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    THE OHIO STATE UNIVERSITY

    $50,000
    COLUMBUS, OH2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    UNIVERSITY OF CONNECTICUT AT STORRS

    $50,000
    STORRS MANSFIELD, CT2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY

    TEGA THERAPEUTICS INC

    $44,827
    SAN DIEGO, CA2025

    BIOMANUFACTURING RESEARCH

    SOUTHERN ILLINOIS UNIVERSITY - EDWARDSVILLE

    $39,241
    NEW YORK, NY2025

    BIOMANUFACTURING RESEARCH

    SIGNATURE SCIENCE LLC

    $24,753
    AUSTIN, TX2025

    EDUCATION AND WORKFORCE DEVELOPMENT RESEARCH AND SERVICE DELIVERY