The Sergey Brin Family Foundation concentrates major funding on biomedical research—especially Parkinson’s disease and related neuroscience—while simultaneously investing heavily in climate and clean-energy systems, decarbonizing shipping, and disaster/wildfire resilience. Grants are primarily directed to leading research universities, specialized research charities, and a set of climate-public-interest intermediaries and collaboratives; occasional large global health and humanitarian gifts appear as well. The foundation favors program- and research-support at scale and partners with both operating nonprofits and funding platforms to move systems-level change.
A defining feature of the Sergey Brin Family Foundation C/o Pacific Foundation Services is its habit of writing very large checks to a small set of research and climate vehicles, especially the Michael J Fox Foundation for Parkinson's Research and the Climate Imperative Foundation. That pattern points to a funder that supports disease research and systems-level climate work rather than many small awards. In the Parkinson’s area, the foundation backs the ASAP Initiative, general operating support, and investigative therapeutics work, including grants to the Michael J Fox Foundation for Parkinson's Research in New York. It also funds neuroscience and biomedical research through universities and institutes, including UCSF Foundation, Stanford, and the Broad Institute, with purposes ranging from research support to drug discovery and wastewater surveillance. Beyond health research, the foundation has made major commitments to decarbonization and climate policy through intermediaries such as Climate Imperative Foundation and United States Energy Foundation. The recent grant record also includes support for wildfire mitigation and resilience, bipolar disorder research, and a limited number of global health and humanitarian gifts.
Parkinson’s disease research is one of the clearest lanes in the grant record. The foundation gave $79,900,301 in 2025 to Michael J Fox Foundation for Parkinson's Research for the ASAP Initiative, and also made $55,400,088 in 2024 for support for Parkinson's disease research. Biomedical research extends beyond one disease area: UCSF Foundation received $27,902,673 in 2025 for research support for Parkinson's disease, plus $20,486,571 in 2023 for discovering drugs for Parkinsons disease and multiple systems atrophy. The portfolio also includes neuroscience and related brain research, such as $17,500,387 in 2025 to Broad Institute Inc for support for CNS research. On the climate side, the foundation used $12,524,587 in 2024 for Resources Legacy Fund to support a wildfire mitigation strategy, showing interest in resilience as well as decarbonization.
Typical grants are large: the 25th percentile is $200,000, the median is $500,000, and the 75th percentile is $2,026,568. The recent record also shows repeated support to the same recipients across multiple years, including Michael J Fox Foundation for Parkinson's Research, Climate Imperative Foundation, United States Energy Foundation, UCSF Foundation, and Board of Trustees of the Leland Stanford Junior University. That repeated pattern suggests ongoing, multi-year relationships rather than one-off awards. The foundation is a regular funder and also makes program-related investments. It funds individuals and operates at regional scope.
$688.7M
$4.3B
$985.6M
$725.2M
Most grants fall between $200K and $2M, with a median of $500K.
25th Percentile
$200K
Median
$500K
75th Percentile
$2M
SERGEY BRIN
DIRECTOR & PRESIDENT
Top 10 recipient countries by grant volume for Sergey Brin Family Foundation C/O Pacific Foundation Services.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 448 | $1.5B | 87.5% |
| 2 |
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Concentrated, high-dollar grants with many repeat payments to core grantees; mix of large institutional gifts to universities and disease foundations plus multi‑million gifts to climate intermediaries and policy organizations. Funding is strategic and systems-focused (research infrastructure, clinical trials, policy campaigns) rather than many small community grants.
Notable grantees: Michael J. Fox Foundation for Parkinson's Research, UCSF Foundation, Board of Trustees of the Leland Stanford Junior University, Climate Imperative Foundation (and ClimateWorks-related collaboratives), Gavi, the Vaccine Alliance
Grant recipients are concentrated in the United States, which accounts for 434 grants, or 91.2% of recipient-country records. Within the recent grant list, San Francisco appears often through Climate Imperative Foundation, United States Energy Foundation, UCSF Foundation, and Rewiring America Inc in Washington, DC. New York appears through Michael J Fox Foundation for Parkinson's Research, while Cambridge, MA appears through Broad Institute Inc. The top state by grant count is Massachusetts, even though 56% of grants go to recipients in the foundation’s headquarters state of California.
The recent grant record is centered on biomedical research, especially Parkinson’s disease and related neuroscience, plus climate and decarbonization intermediaries. Recipients include research universities and institutes such as UCSF Foundation, Stanford, and Broad Institute Inc, along with climate organizations such as Climate Imperative Foundation and United States Energy Foundation.
The grant-size distribution is large: the 25th percentile is $200,000, the median is $500,000, and the 75th percentile is $2,026,568. The recent grants list also includes several awards in the tens of millions, which lifts the overall scale substantially.
Yes. The recent record shows repeat grants to Michael J Fox Foundation for Parkinson's Research, Climate Imperative Foundation, United States Energy Foundation, UCSF Foundation, and Board of Trustees of the Leland Stanford Junior University across 2023, 2024, and 2025. That points to recurring partnerships rather than isolated gifts.
Parkinson’s disease research is a major area, including the ASAP Initiative and research support. The foundation also supports broader CNS research, bipolar disorder research, wastewater surveillance through Scan and WastewaterScan, clean energy and decarbonization, and wildfire mitigation strategy work.
Yes. The recipient-country distribution includes grants to Geneva, which appears in the list through Gavi Alliance for COVAX. The country data also shows smaller numbers of grants to locations coded AS, SN, MP, UK, DA, SF, SZ, NL, and GM.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| Australia |
| 15 |
| $15.9M |
2.9% |
| 3 | Singapore | 9 | $18.8M | 1.8% |
| 4 | Mauritius | 9 | $1.1M | 1.8% |
| 5 | South Africa | 8 | $367K | 1.6% |
| 6 | United Kingdom | 7 | $15.1M | 1.4% |
| 7 | Denmark | 6 | $22.7M | 1.2% |
| 8 | Germany | 3 | $6.8M | 0.6% |
| 9 | Switzerland | 2 | $38.1M | 0.4% |
| 10 | Netherlands | 2 | $10M | 0.4% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $79,900,301 | 2025 | ASAP INITIATIVE |
| CLIMATE IMPERATIVE FOUNDATION | SAN FRANCISCO, CA | $48,998,087 | 2025 | GENERAL OPERATING SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $47,000,292 | 2025 | ASAP INITIATIVE |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $30,104,788 | 2025 | GENERAL OPERATING SUPPORT |
| UNITED STATES ENERGY FOUNDATION | SAN FRANCISCO, CA | $29,000,018 | 2025 | GENERAL OPERATING SUPPORT |
| UCSF FOUNDATION | SAN FRANCISCO, CA | $27,902,673 | 2025 | RESEARCH SUPPORT FOR PARKINSON'S DISEASE |
| UCSF FOUNDATION | SAN FRANCISCO, CA | $25,023,109 | 2025 | RESEARCH SUPPORT |
| DAFGIVING360 | ORLANDO, FL | $25,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $24,098,614 | 2025 | ASAP INITIATIVE |
| BD2 LLC | SANTA MONICA, CA | $20,319,841 | 2025 | SUPPORT FOR BIPOLAR DISORDER RESEARCH |
| BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | STANFORD, CA | $19,799,373 | 2025 | SCAN PROJECT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $18,215,062 | 2025 | GENERAL OPERATING SUPPORT |
| BROAD INSTITUTE INC | CAMBRIDGE, MA | $17,500,387 | 2025 | SUPPORT FOR CNS RESEARCH |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $15,544,516 | 2025 | LRRK2 INVESTIGATIVE THERAPEUTICS EXCHANGE |
| REWIRING AMERICA INC | WASHINGTON, DC | $12,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $10,000,056 | 2025 | PATH TO PREVENTION (P2P) PLATFORM STUDY |
| ASPEN GLOBAL CHANGE INSTITUTE INC | BASALT, CO | $9,987,923 | 2025 | GENERAL OPERATING SUPPORT |
| BLUE MERIDIAN PARTNERS INC | NEW YORK, NY | $9,984,286 | 2025 | BAY AREA SUPPORT |
| CLIMATEWORKS FOUNDATION | SAN FRANCISCO, CA | $7,594,234 | 2025 | GENERAL OPERATING SUPPORT |
| UCSF FOUNDATION | SAN FRANCISCO, CA | $6,601,735 | 2025 | RESEARCH SUPPORT |
| UCSF FOUNDATION | SAN FRANCISCO, CA | $6,600,372 | 2025 | RESEARCH SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $6,400,637 | 2025 | LRRK2 INVESTIGATIVE THERAPEUTICS EXCHANGE |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA | LOS ANGELES, CA | $6,000,152 | 2025 | INSTITUTE FOR CARBON MANAGEMENT |
| STICHTING EUROPEAN CLIMATE FOUNDATION | BERLIN | $6,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| OCEAN ENERGY PATHWAY | LONDON | $6,000,000 | 2025 | ENERGY INITIATIVES |
| BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | STANFORD, CA | $5,588,132 | 2025 | SUPPORT FOR AUTISM RESEARCH |
| TARGET ALS FOUNDATION | NEW YORK, NY | $5,004,210 | 2025 | GENERAL OPERATING SUPPORT |
| MULTIPLIER | SAN FRANCISCO, CA | $5,000,093 | 2025 | ENERGY INITIATIVES |
| TIPPING POINT COMMUNITY | SAN FRANCISCO, CA | $5,000,069 | 2025 | GENERAL OPERATING SUPPORT |
| EARTH FIRE ALLIANCE | SAN FRANCISCO, CA | $5,000,000 | 2025 | WILDFIRE TECHNOLOGY |
| TARA CLIMATE LTD | — | $5,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| PACIFIC ENVIRONMENT AND RESOURCES CENTER | SAN FRANCISCO, CA | $5,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| TARA CLIMATE LTD | — | $5,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| CLIMATEWORKS FOUNDATION | SAN FRANCISCO, CA | $4,993,962 | 2025 | GENERAL OPERATING SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $4,879,236 | 2025 | GENERAL OPERATING SUPPORT |
| BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | STANFORD, CA | $4,014,060 | 2025 | SUPPORT FOR PARKINSON'S DISEASE RESEARCH |
| THE ASPEN INSTITUTE INC | ASPEN, CO | $3,905,764 | 2025 | GENERAL OPERATING SUPPORT |
| INTERNATIONAL LAND AND FOREST TENURE FACILITY | STOCKHOLM | $3,600,000 | 2025 | GENERAL OPERATING SUPPORT |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $3,524,584 | 2025 | GENERAL OPERATING SUPPORT |
| THE NATIONAL WILDLIFE FEDERATION | RESTON, VA | $3,289,143 | 2025 | ENERGY INITIATIVES |
| GLOBAL MARITIME FORUM | COPENHAGEN | $3,074,000 | 2025 | GENERAL OPERATING SUPPORT |
| ELEMENTAL EXCELERATOR INC | HONOLULU, HI | $3,000,000 | 2025 | GENERAL OPERATING SUPPORT |
| UNITED NATIONS FOUNDATION INC | WASHINGTON, DC | $2,981,086 | 2025 | SHIPPING INITIATIVES |
| MICHAEL J FOX FOUNDATION FOR PARKINSON'S RESEARCH | NEW YORK, NY | $2,822,016 | 2025 | SUPPORT PARKINSON'S DISEASE CLINICAL TRIALS |
| C40 CITIES CLIMATE LEADERSHIP GROUP INC | NEW YORK, NY | $2,550,000 | 2025 | GENERAL OPERATING SUPPORT |
| ADVANCED ENERGY INSTITUTE | WASHINGTON, DC | $2,500,388 | 2025 | ENERGY INITIATIVES |
| ROCKY MOUNTAIN INSTITUTE | BOULDER, CO | $2,500,388 | 2025 | GENERAL OPERATING SUPPORT |
| CALSTART INC | PASADENA, CA | $2,500,000 | 2025 | PROGRAMS SUPPORTING TRANSPORTATION |
| BREAKTHROUGH PRIZE IN LIFE SCIENCES FOUNDATION | WASHINGTON, DC | $2,500,000 | 2025 | BREAKTHROUGH PRIZE AND GENERAL CHARITABLE SUPPORT |
| EARTHJUSTICE | SAN FRANCISCO, CA | $2,497,157 | 2025 | GENERAL OPERATING SUPPORT |
GENERAL OPERATING SUPPORT
UNITED STATES ENERGY FOUNDATION
$29,000,018GENERAL OPERATING SUPPORT
UCSF FOUNDATION
$27,902,673RESEARCH SUPPORT FOR PARKINSON'S DISEASE
UCSF FOUNDATION
$25,023,109RESEARCH SUPPORT
DAFGIVING360
$25,000,000GENERAL OPERATING SUPPORT
BD2 LLC
$20,319,841SUPPORT FOR BIPOLAR DISORDER RESEARCH
GENERAL OPERATING SUPPORT
LRRK2 INVESTIGATIVE THERAPEUTICS EXCHANGE
PATH TO PREVENTION (P2P) PLATFORM STUDY
UCSF FOUNDATION
$6,601,735RESEARCH SUPPORT
UCSF FOUNDATION
$6,600,372RESEARCH SUPPORT
LRRK2 INVESTIGATIVE THERAPEUTICS EXCHANGE
REGENTS OF THE UNIVERSITY OF CALIFORNIA
$6,000,152INSTITUTE FOR CARBON MANAGEMENT
STICHTING EUROPEAN CLIMATE FOUNDATION
$6,000,000GENERAL OPERATING SUPPORT
OCEAN ENERGY PATHWAY
$6,000,000ENERGY INITIATIVES
SUPPORT FOR AUTISM RESEARCH
TARGET ALS FOUNDATION
$5,004,210GENERAL OPERATING SUPPORT
EARTH FIRE ALLIANCE
$5,000,000WILDFIRE TECHNOLOGY
TARA CLIMATE LTD
$5,000,000GENERAL OPERATING SUPPORT
TARA CLIMATE LTD
$5,000,000GENERAL OPERATING SUPPORT
GENERAL OPERATING SUPPORT
SUPPORT FOR PARKINSON'S DISEASE RESEARCH
THE ASPEN INSTITUTE INC
$3,905,764GENERAL OPERATING SUPPORT
INTERNATIONAL LAND AND FOREST TENURE FACILITY
$3,600,000GENERAL OPERATING SUPPORT
GENERAL OPERATING SUPPORT
GLOBAL MARITIME FORUM
$3,074,000GENERAL OPERATING SUPPORT
SUPPORT PARKINSON'S DISEASE CLINICAL TRIALS
BREAKTHROUGH PRIZE IN LIFE SCIENCES FOUNDATION
$2,500,000BREAKTHROUGH PRIZE AND GENERAL CHARITABLE SUPPORT