Connecting our community’s generosity to a healthier tomorrow for all.
Prisma Health’s largest recent grant went to USC School of Medicine Greenville, with $36,516,044 in 2023 for operational and community engagement support. That single award signals a grantmaker that uses philanthropy to strengthen health-related institutions and the systems around them, especially in South Carolina. Across its recent grants, the foundation backs medical education, community health infrastructure, and services tied to behavioral health, cancer care and research, pediatrics, rehabilitation, women’s health, and patient support programs. The giving pattern also shows a strong connection to local partners in Greenville, Columbia, Spartanburg, Sumter, Greenwood, and Seneca. Prisma Health has made large commitments to medical education entities such as USC School of Medicine, USC School of Medicine Greenville, and USC Upstate Foundation, while also supporting community-facing organizations like the Community Foundation of Greenville, Greenville Technical College, and Well Partners Dental and Eye Health. The presence of hospitals, colleges, museums, and local service organizations points to a funder that blends health-sector investment with broader community engagement. Most grants are directed within South Carolina, aligning philanthropy closely with the communities it serves.
Medical education and training are a major theme. Prisma Health gave $24,007,500 in 2025 to USC School of Medicine for operational and community engagement support, and $1,500,000 in 2024 to Greenville Technical College for the same purpose. It also supported USC Upstate Foundation with $2,600,000 in 2023 and USC Educational Foundation with $1,300,000 in 2023. Community health access appears alongside education. In Columbia, the foundation awarded $345,000 in 2025 to Well Partners Dental and Eye Health and $200,000 in 2025 to City Of Columbia for op/community engagement. It also made repeated support to Eau Claire Cooperative Health Center Inc, including $200,000 in 2025, and to County Of Greenville, including $247,596 in 2024. Children’s and family-serving organizations also receive support. Grants include $200,000 in 2024 to SC Children’s Theatre, $150,000 in 2024 to EdVenture Children’s Museum, and $101,800 in 2025 to A Child’s Haven.
Prisma Health’s typical grant size sits at $10,000 at the 25th percentile, $17,500 at the median, and $35,312 at the 75th percentile, even as a handful of large awards lift overall annual giving. The pattern includes repeat support to the same recipients across multiple years, such as USC School of Medicine Greenville in 2023 and 2024 and EAU Claire Cooperative Health Center across 2023 through 2025. The foundation is an operating grantmaker rather than an individual-giving funder, and it does not make program-related investments. Its recent grants are labeled mainly as operational/community engagement support, indicating flexible institutional support rather than narrowly restricted project funding.
$31.5M
$3.8B
$136.6M
$111.6M
Most grants fall between $10K and $35K, with a median of $18K.
25th Percentile
$10K
Median
$18K
75th Percentile
$35K
About 97% of grants go to recipients in SC.
Mark S O'Halla
President and CEO of Prisma Health
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Prisma Health’s grantmaking is overwhelmingly South Carolina-focused: 97% of grants go to recipients in the HQ state, and the top giving state is SC. Recent awards cluster in Greenville and Columbia, with additional grants in Spartanburg, Sumter, Greenwood, Seneca, and Taylors. Greenville appears frequently through recipients such as Greenville Technical College, the Community Foundation of Greenville, and County Of Greenville, while Columbia shows up through USC Educational Foundation, Midlands Tech Coll Foundation, and City Of Columbia. All recent grants in the dataset went to US recipients.
Recent grants go to medical schools, technical colleges, community health centers, local nonprofits, and public-serving institutions. Examples in the data include USC School of Medicine Greenville, Greenville Technical College, Eau Claire Cooperative Health Center Inc, and Community Foundation of Greenville, usually for operational or community engagement support.
The listed focus areas are behavioral health, cancer care and research, pediatrics and children's services, medical education and scholarships, rehabilitation, women's health, and patient support programs. The recent grants reflect that mix, especially through medical education and community health access.
Yes. 97% of grants go to recipients in South Carolina, and SC is the top state by grant count. The recent grants list is entirely US-based, with South Carolina cities including Greenville, Columbia, Spartanburg, Sumter, Greenwood, Seneca, and Taylors.
The typical grant size is $10,000 at the 25th percentile, $17,500 at the median, and $35,312 at the 75th percentile. Recent giving also includes several much larger institutional awards, especially for medical education and community engagement support.
Yes. USC School of Medicine Greenville appears in 2023 and 2024, USC School of Medicine appears in 2025, and EAU Claire Cooperative Health Center Inc appears in 2023, 2024, and 2025. The repeat pattern suggests ongoing support for some institutions rather than one-time gifts only.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| USC School of Medicine | Greenville, SC | $24,007,500 | 2025 | op/community engagement |
| Prisma Health-Upstate Foundation | Greenville, SC | $2,290,394 | 2025 | op/community engagement |
| Piedmont Technical College | Greenwood, SC | $1,007,180 | 2025 | op/community engagement |
| Community Foundation Of Greenville | Greenville, SC | $775,000 | 2025 | op/community engagement |
| Tuomey Foundation | Sumter, SC | $412,306 | 2025 | op/community engagement |
| Well Partners Dental and Eye Health | Columbia, SC | $345,000 | 2025 | op/community engagement |
| Eau Claire Cooperative Health Center Inc | Columbia, SC | $200,000 | 2025 | op/community engagement |
| City Of Columbia | Columbia, SC | $200,000 | 2025 | op/community engagement |
| Greenville County Rec | Taylors, SC | $150,000 | 2025 | op/community engagement |
| County Of Greenville | Greenville, SC | $125,000 | 2025 | op/community engagement |
| A Child's Haven | Greenville, SC | $101,800 | 2025 | op/community engagement |
| SC Children's Theatre | Greenville, SC | $100,000 | 2025 | op/community engagement |
| Foothills Area YMCA | Seneca, SC | $100,000 | 2025 | op/community engagement |
| The Mental Illness Recovery Center Inc (MIRCI) | Columbia, SC | $90,000 | 2025 | op/community engagement |
| Greenville Chamber Of Commerce | Greenville, SC | $82,500 | 2025 | op/community engagement |
| Favor Upstate | Greenville, SC | $78,000 | 2025 | op/community engagement |
| AHA ECC Distribution | Mt Pleasant, SC | $67,500 | 2025 | op/community engagement |
| SC Research Foundation | Columbia, SC | $62,500 | 2025 | op/community engagement |
| USC Educational Foundation | Columbia, SC | $57,500 | 2025 | op/community engagement |
| City Of Sumter | Sumter, SC | $55,500 | 2025 | op/community engagement |
| The Free Medical Clinic | Columbia, SC | $50,000 | 2025 | op/community engagement |
| Greenville Free Medical Clinic | Greenville, SC | $50,000 | 2025 | op/community engagement |
| MedNeed of SC | Columbia, SC | $36,250 | 2025 | op/community engagement |
| Samaritan Health Clinic Of | Easley, SC | $30,000 | 2025 | op/community engagement |
| City Center Partnership Inc | Columbia, SC | $30,000 | 2025 | op/community engagement |
| March Of Dimes | Greenville, SC | $30,000 | 2025 | op/community engagement |
| James R Clark Sickle Cell Foundation | Columbia, SC | $30,000 | 2025 | op/community engagement |
| American Cancer Society Inc | Greenville, SC | $25,000 | 2025 | op/community engagement |
| Columbia Urban League | Columbia, SC | $25,000 | 2025 | op/community engagement |
| Greenville Symphony Association | Greenville, SC | $25,000 | 2025 | op/community engagement |
| Notus Sports | Greenville, SC | $25,000 | 2025 | op/community engagement |
| UNCF Upstate | Greenville, SC | $25,000 | 2025 | op/community engagement |
| Riverbanks Zoo | Columbia, SC | $25,000 | 2025 | op/community engagement |
| Greater Cola Chamber Of Commerce | Greenville, SC | $23,000 | 2025 | op/community engagement |
| United Way of Greenville County Inc | Greenville, SC | $20,500 | 2025 | op/community engagement |
| Mental Health America of SC | Columbia, SC | $20,000 | 2025 | op/community engagement |
| Greenville Zoo | Greenville, SC | $20,000 | 2025 | op/community engagement |
| Pathways to Healing | Columbia, SC | $20,000 | 2025 | op/community engagement |
| SC Philharmonic Inc | Columbia, SC | $20,000 | 2025 | op/community engagement |
| Alzheimer's Association | Greenville, SC | $20,000 | 2025 | op/community engagement |
| Julie Valentine Center | Greenville, SC | $20,000 | 2025 | op/community engagement |
| JDRF International | New York, NY | $20,000 | 2025 | op/community engagement |
| Feonix-Mobility Rising | Lincoln, NE | $20,000 | 2025 | op/community engagement |
| Travelers Rest Farmers Market | Travelers Rest, SC | $20,000 | 2025 | op/community engagement |
| Livewell Greenville | Greenville, SC | $20,000 | 2025 | op/community engagement |
| Lexington Chamber Of Commerce | Lexington, SC | $18,000 | 2025 | op/community engagement |
| City Of Greenville SC | Greenville, SC | $17,500 | 2025 | op/community engagement |
| Laurens Co Chamber Of Commerce | Greenville, SC | $17,000 | 2025 | op/community engagement |
| Congaree Vista Guild | Columbia, SC | $16,000 | 2025 | op/community engagement |
| Artisphere | Greenville, SC | $15,000 | 2025 | op/community engagement |
USC School of Medicine
$24,007,500op/community engagement
Prisma Health-Upstate Foundation
$2,290,394op/community engagement
Piedmont Technical College
$1,007,180op/community engagement
Community Foundation Of Greenville
$775,000op/community engagement
Tuomey Foundation
$412,306op/community engagement
Well Partners Dental and Eye Health
$345,000op/community engagement
Eau Claire Cooperative Health Center Inc
$200,000op/community engagement
City Of Columbia
$200,000op/community engagement
Greenville County Rec
$150,000op/community engagement
County Of Greenville
$125,000op/community engagement
A Child's Haven
$101,800op/community engagement
SC Children's Theatre
$100,000op/community engagement
Foothills Area YMCA
$100,000op/community engagement
The Mental Illness Recovery Center Inc (MIRCI)
$90,000op/community engagement
Greenville Chamber Of Commerce
$82,500op/community engagement
Favor Upstate
$78,000op/community engagement
AHA ECC Distribution
$67,500op/community engagement
SC Research Foundation
$62,500op/community engagement
USC Educational Foundation
$57,500op/community engagement
City Of Sumter
$55,500op/community engagement
The Free Medical Clinic
$50,000op/community engagement
Greenville Free Medical Clinic
$50,000op/community engagement
MedNeed of SC
$36,250op/community engagement
Samaritan Health Clinic Of
$30,000op/community engagement
City Center Partnership Inc
$30,000op/community engagement
March Of Dimes
$30,000op/community engagement
James R Clark Sickle Cell Foundation
$30,000op/community engagement
American Cancer Society Inc
$25,000op/community engagement
Columbia Urban League
$25,000op/community engagement
Greenville Symphony Association
$25,000op/community engagement
Notus Sports
$25,000op/community engagement
UNCF Upstate
$25,000op/community engagement
Riverbanks Zoo
$25,000op/community engagement
Greater Cola Chamber Of Commerce
$23,000op/community engagement
United Way of Greenville County Inc
$20,500op/community engagement
Mental Health America of SC
$20,000op/community engagement
Greenville Zoo
$20,000op/community engagement
Pathways to Healing
$20,000op/community engagement
SC Philharmonic Inc
$20,000op/community engagement
Alzheimer's Association
$20,000op/community engagement
Julie Valentine Center
$20,000op/community engagement
JDRF International
$20,000op/community engagement
Feonix-Mobility Rising
$20,000op/community engagement
Travelers Rest Farmers Market
$20,000op/community engagement
Livewell Greenville
$20,000op/community engagement
Lexington Chamber Of Commerce
$18,000op/community engagement
City Of Greenville SC
$17,500op/community engagement
Laurens Co Chamber Of Commerce
$17,000op/community engagement
Congaree Vista Guild
$16,000op/community engagement
Artisphere
$15,000op/community engagement