Our mission is to cure or prevent all disease. We build technology, generate large biological datasets, and develop AI-powered models and tools to advance scientific discovery and accelerate biomedical research.
Chan Zuckerberg Biohub Inc directs large research grants to universities and medical research institutions for scientific and medical research. Its recent awards are dominated by multi-million-dollar commitments, including $12,786,641 to UC San Francisco in 2024 and $12,257,389 to Regents of the University of California San Francisco in 2025. Stanford also appears at the top of the list, with $11,626,018 to The Board of Trustees of the Leland Stanford Junior University in 2025 and $11,450,044 to Stanford University in 2024. The pattern points to a funder that backs major research systems rather than small project awards. The foundation’s stated mission is to cure or prevent all disease, and its existing focus areas show how it pursues that goal: cell biology, computational biology and AI for biology, imaging and microscopy, inflammation research, immune cell engineering, bioengineering, open-source scientific software and data platforms, and postdoctoral fellowships and investigator support. The grant list also shows sustained support for the University of California system and for other academic medical centers. Its program-related investment activity and large asset base place it among funders with the capacity to support long-term scientific infrastructure as well as research awards.
Computational biology and AI for biology are central to the foundation’s work. In 2025 it gave $2,973,388 to the University of Illinois Foundation in Champaign for scientific and medical research, and the focus-area list identifies AI for biology as a standing priority. Its grantmaking also supports major academic research hubs in the Midwest and Northeast. Examples include $2,868,865 to the University of Chicago in 2025 and $2,826,739 to Northwestern University in 2025, both for scientific and medical research. The foundation backs open scientific infrastructure as part of its biomedical strategy. In 2025 it awarded $1,442,193 to The Trustees of Columbia University in the City of New York, again for scientific and medical research, alongside focus areas that include open-source scientific software and data platforms. Research support extends to investigator-level capacity as well, with postdoctoral fellowships and investigator support listed among its ongoing focus areas.
$40.4M
$1.5B
$99.6M
$142.4M
Most grants fall between $743K and $11.4M, with a median of $5.9M.
25th Percentile
$743K
Median
$5.9M
75th Percentile
$11.4M
BEN ROH
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Typical grants are large: the 25th percentile is $743,066, the median is $5,949,062, and the 75th percentile is $11,391,379. That distribution shows a portfolio built around substantial research awards rather than many small checks. The recipient list also suggests repeat support over time, with several institutions appearing in multiple years, including UC San Francisco, Stanford, UC Berkeley, Northwestern, University of Chicago, and Columbia. The foundation is classified as a regular funder, funds organizations rather than individuals, and makes program-related investments.
All recent grants in the dataset went to US recipients. California receives the largest share of awards, accounting for 60% of grants, with a cluster in San Francisco, Palo Alto, Redwood City, and Berkeley. New York is the top state by grant count, with recipients in New York City and one grant to Columbia in New York. Illinois also appears repeatedly, including Champaign, Chicago, Evanston, and Urbana. The geographic pattern is regional, centered on major research universities and academic medical centers.
It funds research institutions, scientists and researchers, medical research laboratories, universities, and academic medical centers. The grants in the dataset are all for scientific and medical research, and the recipients include major university systems and research universities.
Its listed focus areas are cell biology, computational biology and AI for biology, imaging and microscopy, inflammation research, immune cell engineering, bioengineering, open-source scientific software and data platforms, and postdoctoral fellowships and investigator support.
The grant-size distribution is very large: the 25th percentile is $743,066, the median is $5,949,062, and the 75th percentile is $11,391,379. Recent awards include several seven-figure grants and multiple awards above $10 million.
Yes. Several recipients appear across multiple years, including UC San Francisco, Stanford, UC Berkeley, Northwestern, University of Chicago, and Columbia. That pattern suggests repeated institutional support rather than one-time funding only.
No. The foundation’s classification indicates it funds organizations, and it is marked as funds individuals: false.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO | SAN FRANCISCO, CA | $12,257,389 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | REDWOOD CITY, CA | $11,626,018 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY | BERKELEY, CA | $5,535,784 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| UNIVERSITY OF ILLINOIS FOUNDATION | CHAMPAIGN, IL | $2,973,388 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| UNIVERSITY OF CHICAGO | CHICAGO, IL | $2,868,865 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| NORTHWESTERN UNIVERSITY | EVANSTON, IL | $2,826,739 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | NEW YORK, NY | $1,442,193 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| YALE UNIVERSITY | NEW HAVEN, CT | $434,943 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| THE ROCKEFELLER UNIVERSITY | NEW YORK, NY | $217,471 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| UNIVERSITY OF CALIFORNIA BERKELEY FOUNDATION | BERKELEY, CA | $200,000 | 2025 | SCIENTIFIC AND MEDICAL RESEARCH |
| UC SAN FRANCISCO | SAN FRANCISCO, CA | $12,786,641 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| STANFORD UNIVERSITY | PALO ALTO, CA | $11,450,044 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| UC BERKELEY | BERKELEY, CA | $5,850,000 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| NORTHWESTERN UNIVERSITY | EVANSTON, IL | $971,739 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | URBANA, IL | $666,841 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| UNIVERSITY OF CHICAGO | CHICAGO, IL | $471,739 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | NEW YORK, NY | $166,667 | 2024 | SCIENTIFIC AND MEDICAL RESEARCH |
| UC SAN FRANCISCO | SAN FRANCISCO, CA | $11,796,796 | 2023 | SCIENTIFIC AND MEDICALRESEARCH |
| STANFORD UNIVERSITY | PALO ALTO, CA | $11,215,383 | 2023 | SCIENTIFIC AND MEDICALRESEARCH |
| UC BERKELEY | BERKELEY, CA | $6,048,125 | 2023 | SCIENTIFIC AND MEDICALRESEARCH |
REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$12,257,389SCIENTIFIC AND MEDICAL RESEARCH
SCIENTIFIC AND MEDICAL RESEARCH
REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY
$5,535,784SCIENTIFIC AND MEDICAL RESEARCH
SCIENTIFIC AND MEDICAL RESEARCH
UC SAN FRANCISCO
$12,786,641SCIENTIFIC AND MEDICAL RESEARCH
UC BERKELEY
$5,850,000SCIENTIFIC AND MEDICAL RESEARCH
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
$666,841SCIENTIFIC AND MEDICAL RESEARCH
SCIENTIFIC AND MEDICAL RESEARCH
UC SAN FRANCISCO
$11,796,796SCIENTIFIC AND MEDICALRESEARCH
UC BERKELEY
$6,048,125SCIENTIFIC AND MEDICALRESEARCH