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    3. Chan Zuckerberg Biohub
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    Chan Zuckerberg Biohub

    ActivoMedical ResearchRealiza PRIs
    SAN FRANCISCO, CASitio web4155493300

    About Chan Zuckerberg Biohub

    Our mission is to cure or prevent all disease. We build technology, generate large biological datasets, and develop AI-powered models and tools to advance scientific discovery and accelerate biomedical research.

    Focus Areas

    Cell biologyComputational biology and AI for biologyImaging and microscopyInflammation researchImmune cell engineeringBioengineeringOpen-source scientific software and data platformsPostdoctoral fellowships and investigator support

    Who They Fund

    research institutionsscientists and researchersmedical research laboratoriesuniversities and academic medical centers

    About Chan Zuckerberg Biohub

    Chan Zuckerberg Biohub Inc directs large research grants to universities and medical research institutions for scientific and medical research. Its recent awards are dominated by multi-million-dollar commitments, including $12,786,641 to UC San Francisco in 2024 and $12,257,389 to Regents of the University of California San Francisco in 2025. Stanford also appears at the top of the list, with $11,626,018 to The Board of Trustees of the Leland Stanford Junior University in 2025 and $11,450,044 to Stanford University in 2024. The pattern points to a funder that backs major research systems rather than small project awards. The foundation’s stated mission is to cure or prevent all disease, and its existing focus areas show how it pursues that goal: cell biology, computational biology and AI for biology, imaging and microscopy, inflammation research, immune cell engineering, bioengineering, open-source scientific software and data platforms, and postdoctoral fellowships and investigator support. The grant list also shows sustained support for the University of California system and for other academic medical centers. Its program-related investment activity and large asset base place it among funders with the capacity to support long-term scientific infrastructure as well as research awards.

    What Chan Zuckerberg Biohub Funds

    Computational biology and AI for biology are central to the foundation’s work. In 2025 it gave $2,973,388 to the University of Illinois Foundation in Champaign for scientific and medical research, and the focus-area list identifies AI for biology as a standing priority. Its grantmaking also supports major academic research hubs in the Midwest and Northeast. Examples include $2,868,865 to the University of Chicago in 2025 and $2,826,739 to Northwestern University in 2025, both for scientific and medical research. The foundation backs open scientific infrastructure as part of its biomedical strategy. In 2025 it awarded $1,442,193 to The Trustees of Columbia University in the City of New York, again for scientific and medical research, alongside focus areas that include open-source scientific software and data platforms. Research support extends to investigator-level capacity as well, with postdoctoral fellowships and investigator support listed among its ongoing focus areas.

    How Chan Zuckerberg Biohub Gives

    Financial Snapshot

    Annual Giving

    $40.4M

    Total Assets

    $1.5B

    Total Revenue

    $99.6M

    Total Expenses

    $142.4M

    Typical Grant Size

    Most grants fall between $743K and $11.4M, with a median of $5.9M.

    25th Percentile

    $743K

    Median

    $5.9M

    75th Percentile

    $11.4M

    Geographic Reach

    Regional4 states funded
    Intensidad de financiamiento
    Baja
    Alta
    Sede

    Leadership

    BEN ROH

    Accepts unsolicited proposals

    Deep Analysis

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    EIN (identificación fiscal): 81-1669175Último Formulario 990: 2025Activos totales: 1477,1 M US$3 declaraciones registradasEncuentra su declaración 990 completa →
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    Funding Style

    research project fundingproject-based grantsscientific/medical research support

    Topics

    scientific researchmedical researchbiomedical researchclinical research

    Typical grants are large: the 25th percentile is $743,066, the median is $5,949,062, and the 75th percentile is $11,391,379. That distribution shows a portfolio built around substantial research awards rather than many small checks. The recipient list also suggests repeat support over time, with several institutions appearing in multiple years, including UC San Francisco, Stanford, UC Berkeley, Northwestern, University of Chicago, and Columbia. The foundation is classified as a regular funder, funds organizations rather than individuals, and makes program-related investments.

    Where Chan Zuckerberg Biohub Makes Grants

    All recent grants in the dataset went to US recipients. California receives the largest share of awards, accounting for 60% of grants, with a cluster in San Francisco, Palo Alto, Redwood City, and Berkeley. New York is the top state by grant count, with recipients in New York City and one grant to Columbia in New York. Illinois also appears repeatedly, including Champaign, Chicago, Evanston, and Urbana. The geographic pattern is regional, centered on major research universities and academic medical centers.

    Frequently Asked Questions About Chan Zuckerberg Biohub

    What kind of organizations does Chan Zuckerberg Biohub Inc fund?

    It funds research institutions, scientists and researchers, medical research laboratories, universities, and academic medical centers. The grants in the dataset are all for scientific and medical research, and the recipients include major university systems and research universities.

    What are the foundation’s main focus areas?

    Its listed focus areas are cell biology, computational biology and AI for biology, imaging and microscopy, inflammation research, immune cell engineering, bioengineering, open-source scientific software and data platforms, and postdoctoral fellowships and investigator support.

    How large are its typical grants?

    The grant-size distribution is very large: the 25th percentile is $743,066, the median is $5,949,062, and the 75th percentile is $11,391,379. Recent awards include several seven-figure grants and multiple awards above $10 million.

    Does it give recurring grants to the same institutions?

    Yes. Several recipients appear across multiple years, including UC San Francisco, Stanford, UC Berkeley, Northwestern, University of Chicago, and Columbia. That pattern suggests repeated institutional support rather than one-time funding only.

    Can individuals apply for funding?

    No. The foundation’s classification indicates it funds organizations, and it is marked as funds individuals: false.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCOSAN FRANCISCO, CA$12,257,3892025SCIENTIFIC AND MEDICAL RESEARCH
    THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITYREDWOOD CITY, CA$11,626,0182025SCIENTIFIC AND MEDICAL RESEARCH
    REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEYBERKELEY, CA$5,535,7842025SCIENTIFIC AND MEDICAL RESEARCH
    UNIVERSITY OF ILLINOIS FOUNDATIONCHAMPAIGN, IL$2,973,3882025SCIENTIFIC AND MEDICAL RESEARCH
    UNIVERSITY OF CHICAGOCHICAGO, IL$2,868,8652025SCIENTIFIC AND MEDICAL RESEARCH
    NORTHWESTERN UNIVERSITYEVANSTON, IL$2,826,7392025SCIENTIFIC AND MEDICAL RESEARCH
    THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKNEW YORK, NY$1,442,1932025SCIENTIFIC AND MEDICAL RESEARCH
    YALE UNIVERSITYNEW HAVEN, CT$434,9432025SCIENTIFIC AND MEDICAL RESEARCH
    THE ROCKEFELLER UNIVERSITYNEW YORK, NY$217,4712025SCIENTIFIC AND MEDICAL RESEARCH
    UNIVERSITY OF CALIFORNIA BERKELEY FOUNDATIONBERKELEY, CA$200,0002025SCIENTIFIC AND MEDICAL RESEARCH
    UC SAN FRANCISCOSAN FRANCISCO, CA$12,786,6412024SCIENTIFIC AND MEDICAL RESEARCH
    STANFORD UNIVERSITYPALO ALTO, CA$11,450,0442024SCIENTIFIC AND MEDICAL RESEARCH
    UC BERKELEYBERKELEY, CA$5,850,0002024SCIENTIFIC AND MEDICAL RESEARCH
    NORTHWESTERN UNIVERSITYEVANSTON, IL$971,7392024SCIENTIFIC AND MEDICAL RESEARCH
    THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOISURBANA, IL$666,8412024SCIENTIFIC AND MEDICAL RESEARCH
    UNIVERSITY OF CHICAGOCHICAGO, IL$471,7392024SCIENTIFIC AND MEDICAL RESEARCH
    TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKNEW YORK, NY$166,6672024SCIENTIFIC AND MEDICAL RESEARCH
    UC SAN FRANCISCOSAN FRANCISCO, CA$11,796,7962023SCIENTIFIC AND MEDICALRESEARCH
    STANFORD UNIVERSITYPALO ALTO, CA$11,215,3832023SCIENTIFIC AND MEDICALRESEARCH
    UC BERKELEYBERKELEY, CA$6,048,1252023SCIENTIFIC AND MEDICALRESEARCH

    REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO

    $12,257,389
    SAN FRANCISCO, CA2025

    SCIENTIFIC AND MEDICAL RESEARCH

    THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

    $11,626,018
    REDWOOD CITY, CA2025

    SCIENTIFIC AND MEDICAL RESEARCH

    REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY

    $5,535,784
    BERKELEY, CA2025

    SCIENTIFIC AND MEDICAL RESEARCH

    UNIVERSITY OF ILLINOIS FOUNDATION

    $2,973,388
    CHAMPAIGN, IL2025

    SCIENTIFIC AND MEDICAL RESEARCH

    UNIVERSITY OF CHICAGO

    $2,868,865
    CHICAGO, IL2025

    SCIENTIFIC AND MEDICAL RESEARCH

    NORTHWESTERN UNIVERSITY

    $2,826,739
    EVANSTON, IL2025

    SCIENTIFIC AND MEDICAL RESEARCH

    THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

    $1,442,193
    NEW YORK, NY2025

    SCIENTIFIC AND MEDICAL RESEARCH

    YALE UNIVERSITY

    $434,943
    NEW HAVEN, CT2025

    SCIENTIFIC AND MEDICAL RESEARCH

    THE ROCKEFELLER UNIVERSITY

    $217,471
    NEW YORK, NY2025

    SCIENTIFIC AND MEDICAL RESEARCH

    UNIVERSITY OF CALIFORNIA BERKELEY FOUNDATION

    $200,000
    BERKELEY, CA2025

    SCIENTIFIC AND MEDICAL RESEARCH

    UC SAN FRANCISCO

    $12,786,641
    SAN FRANCISCO, CA2024

    SCIENTIFIC AND MEDICAL RESEARCH

    STANFORD UNIVERSITY

    $11,450,044
    PALO ALTO, CA2024

    SCIENTIFIC AND MEDICAL RESEARCH

    UC BERKELEY

    $5,850,000
    BERKELEY, CA2024

    SCIENTIFIC AND MEDICAL RESEARCH

    NORTHWESTERN UNIVERSITY

    $971,739
    EVANSTON, IL2024

    SCIENTIFIC AND MEDICAL RESEARCH

    THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

    $666,841
    URBANA, IL2024

    SCIENTIFIC AND MEDICAL RESEARCH

    UNIVERSITY OF CHICAGO

    $471,739
    CHICAGO, IL2024

    SCIENTIFIC AND MEDICAL RESEARCH

    TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK

    $166,667
    NEW YORK, NY2024

    SCIENTIFIC AND MEDICAL RESEARCH

    UC SAN FRANCISCO

    $11,796,796
    SAN FRANCISCO, CA2023

    SCIENTIFIC AND MEDICALRESEARCH

    STANFORD UNIVERSITY

    $11,215,383
    PALO ALTO, CA2023

    SCIENTIFIC AND MEDICALRESEARCH

    UC BERKELEY

    $6,048,125
    BERKELEY, CA2023

    SCIENTIFIC AND MEDICALRESEARCH