To bring relief to sufferers, globally, who are afflicted with debilitating headaches, including migraine and cluster headaches, by funding research focused on finding a cure; to assemble researchers, physicians, sufferers, family and friends to advance research and achieve freedom from pain.
The Will Erwin Headache Research Foundation’s defining grantmaking pattern is its repeated, high-dollar support for the Will Erwin Headache Research Center at Memorial Hermann Foundation in Houston. Across 2023, 2024, and 2025, the foundation directed major funding to open and sustain that center for people suffering from debilitating headaches, including migraine and cluster headaches, while also supporting a symptom database tied to the center’s research work. That repeated investment shows a funder built around research infrastructure as much as individual studies. Its stated purpose is to bring relief to people afflicted with debilitating headaches by funding research focused on finding a cure and by bringing together researchers, physicians, sufferers, family, and friends to advance research and reduce pain. The recent grants show that mission in practice: most of the giving is concentrated in a single Houston medical-research relationship, with Memorial Hermann Foundation receiving the foundation’s largest awards in successive years. The foundation also made a smaller grant to the University of Houston, showing that its giving is not limited entirely to one institution. Still, the center-funding pattern dominates the profile and indicates a narrow, research-centered philanthropic strategy.
The foundation’s core work is headache research. It gave $525,000 in 2023, $400,000 in 2024, and $400,000 in 2025 to Memorial Hermann Foundation to open the Will Erwin Headache Research Center for people with debilitating headaches, including migraine and cluster headaches, and to create a symptom database. Migraine and cluster headache research are the clearest subject areas in the grant history. The center funding explicitly names both conditions, and the related program description adds clinical research and neurological disorder research. There is also evidence of broader research-enabling support. The foundation’s active programs include funding to establish the center at Memorial Hermann Mischer Neuroscience Institute, which points to capacity-building for clinical and research work rather than only one-off project grants. One smaller 2024 grant went to the University of Houston for the golf team, showing that the portfolio includes a grant outside its main medical focus.
$400K
$105K
$383K
$524K
Most grants fall between $204K and $463K, with a median of $400K.
25th Percentile
$204K
Median
$400K
75th Percentile
$463K
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Typical grant size is large: the 25th percentile is $203,750, the median is $400,000, and the 75th percentile is $462,500. That distribution fits a pattern of major institutional grants rather than small competitive awards. The recent record also shows repetition over time. Memorial Hermann Foundation appears in 2023, 2024, and 2025, which suggests ongoing support for the same research effort rather than a one-time gift. The foundation is a public charity, gives locally, and does not fund individuals or make program-related investments. The active grant programs also say it does not accept unsolicited requests.
Giving is entirely local and entirely within Texas: 100% of grants went to recipients in the HQ state, and Texas is also the top state by grant count. The recipient cities in the recent grants are all Houston. That includes Memorial Hermann Foundation and the University of Houston, both in Houston, TX. No non-U.S. recipient countries appear in the grant data.
It funds headache research, especially work tied to migraine and cluster headaches. The active programs focus on research dedicated to finding a cure for debilitating headaches and on establishing the Will Erwin Headache Research Center at Memorial Hermann Mischer Neuroscience Institute.
No. Both active grant programs state that it does not accept unsolicited applications, so its giving appears to be directed through its own program relationships rather than open requests.
The grant-size distribution is high: p25 is $203,750, median is $400,000, and p75 is $462,500. Recent awards include multiple grants at or near the median level, which points to sizable institutional support.
Its giving is local, and 100% of grants in the available data went to recipients in Texas. The recent grants list shows Houston recipients only, so the footprint is concentrated in its home metro.
The recent grant history includes funding to open the Will Erwin Headache Research Center and create a symptom database for people with debilitating headaches, including migraine and cluster headaches. A smaller grant also supported the University of Houston golf team.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| MEMORIAL HERMANN FOUNDATION | HOUSTON, TX | $400,000 | 2025 | TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEARCH CENTER FOR THOSE SUFFERING FROM DEBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DEBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. |
| MEMORIAL HERMANN FOUNDATION | HOUSTON, TX | $400,000 | 2024 | TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEACH CENTER FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. |
| UNIVERSITY OF HOUSTON | HOUSTON, TX | $7,500 | 2024 | TO PROVIDE FUNDING TO FUND THE UNIVERSITY OF HOUSTON FOR THE GOLF TEAM |
| MEMORIAL HERMANN FOUNDATION | HOUSTON, TX | $525,000 | 2023 | TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEACH CENTER FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. |
TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEARCH CENTER FOR THOSE SUFFERING FROM DEBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DEBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES.
TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEACH CENTER FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES.
UNIVERSITY OF HOUSTON
$7,500TO PROVIDE FUNDING TO FUND THE UNIVERSITY OF HOUSTON FOR THE GOLF TEAM
TO PROVIDE FUNDING TO OPEN THE WILL ERWIN HEADACHE RESEACH CENTER FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES. TO CREATE A DATABASE OF SYMPTOMS FOR THOSE SUFFERING FROM MIGRAINE AND CLUSTER HEADACHES. TO FUND RESEARCH BY NEUROLOGISTS FOR THOSE SUFFERING FROM DIBILITATING HEADACHES, INCLUDING MIGRAINE AND CLUSTER HEADACHES.