The Nancy Lurie Marks Family Foundation concentrates its giving on biomedical and clinical research—primarily through large, multi-year grants to major hospitals and academic medical centers in Massachusetts and nearby states—and also supports higher‑education institutions. Grants are sizable and often repeat to the same organizations, with a notable interest in clinical specialties (eye/ear, autism) and research infrastructure at elite universities and medical centers.
Concentrated, high-dollar funding with repeat multi-grant relationships; a small number of large institutional grantees receive the bulk of support rather than many small, one-off grants.
The Nancy Lurie Marks Family Foundation’s recent giving is anchored by repeated, large grants to Massachusetts General Hospital, including awards of $1,422,500 in 2024 and $1,366,666 in 2025. That pattern points to a foundation that backs sustained biomedical and clinical work rather than one-off support, with a strong tilt toward autism-related research and clinical programs at major hospitals and academic medical centers. Its grantmaking also reaches university partners such as Harvard College, MIT, and Rutgers, alongside specialty medical institutions including Massachusetts Eye and Ear Infirmary and Beth Israel Deaconess Medical Center. A 2025 grant of $1,000,000 to the Lurie Family Autism Center Clinical Program Fund shows direct support for autism clinical programming, while other awards connect to medical research infrastructure and research training. The foundation’s portfolio includes both research and public-welfare grants, but the core pattern is multi-year institutional support for biomedical science, clinical translation, and autism-focused work in Massachusetts and nearby states. Grants are often substantial, and the same recipients appear across multiple years, indicating long-running relationships with selected institutions.
Autism is the clearest throughline in the foundation’s programmatic work. Through its Translational Science Grants, it supports efforts to move basic biomedical findings into diagnosis, treatment, communication tools, and services for autistic individuals. The Major Projects programs add another layer, funding large multi-year initiatives through internal RFPs for measurable impact on the autism community. It also supports research training and faculty development. Career Development Awards are designed for early- to mid-career scientists, including postdoctoral fellows and researchers moving toward tenure-track independence. A third strand is clinical and institutional research support. The foundation has funded Massachusetts Eye and Ear Infirmary for medical research, and it has also made grants to Beth Israel Deaconess Medical Center and Maine Medical Center. Education grants to universities such as Harvard College, Thomas Jefferson University, and Rutgers University suggest continued backing for research environments around those institutions.
$9.7M
$119.9M
$13.7M
$13.8M
Most grants fall between $425 and $138K, with a median of $25K.
25th Percentile
$425
Median
$25K
75th Percentile
$138K
Top 2 recipient countries by grant volume for Nancy Lurie Marks Family Foundation.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 154 | $26.5M | 99.3% |
| 2 | Germany |
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Notable grantees: Massachusetts General Hospital, President and Fellows of Harvard College, Maine Medical Center, Massachusetts Eye and Ear Infirmary, Lurie Family Autism Center Clinical Program Fund
Typical grant size is uneven and leans large: p25 is $425, median is $25,000, and p75 is $137,538. The recent list shows both modest awards and multi-hundred-thousand-dollar institutional grants, with some grants exceeding $1 million. Recipients repeat across multiple years, especially major medical centers and universities, which fits a multi-year institutional funding model. The foundation does not fund individuals and does not make program-related investments. Several active programs rely on internal RFPs or competitive solicitation, and unsolicited applications are not accepted.
Giving is highly concentrated in Massachusetts: 77% of grants go to recipients in the HQ state, and Massachusetts is also the top state by grant count. Boston is the main recipient city, with repeated grants to Boston-based institutions such as Massachusetts General Hospital, Harvard College, Massachusetts Eye and Ear Infirmary, Beth Israel Deaconess Medical Center, and Massachusetts Advocates for Children. Outside Massachusetts, recent grants reached Westbrook, Maine; Philadelphia, Pennsylvania; Piscataway, New Jersey; and New York, New York. All recent grants in the dataset went to U.S. recipients.
Its giving centers on biomedical and clinical research, especially autism-related work. Active programs include Translational Science Grants, Career Development Awards, Autism Grants focused on advocacy and education, and Major Projects grants for multi-year institutional initiatives with measurable outcomes.
No. The foundation does not fund individuals. Its recent grants go to hospitals, universities, and nonprofit organizations such as Massachusetts General Hospital, Harvard College, and Massachusetts Advocates for Children.
The grant-size distribution is wide. The 25th percentile is $425, the median is $25,000, and the 75th percentile is $137,538, showing that many awards are modest but a substantial share are much larger institutional grants.
Major Projects grants are awarded through an internal RFP process and competitive solicitation to a smaller, select group of institutions. The programs are described as multi-year and tied to innovative projects with measurable outcomes and impact on the autism community.
Most grants go to Massachusetts recipients, and 77% of grants are in the HQ state. Boston-based institutions receive a large share of the awards, alongside other U.S. recipients in Maine, Pennsylvania, New Jersey, and New York.
2026
Source: IRS Form 990-PF, fiscal year 2026.
| 1 |
| $75K |
0.7% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| CHILDREN'S HOSPITAL OF PHILADELPHIA | PHILADELPHIA, PA | $2,437,500 | 2026 | MEDICAL RESEARCH |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | PHILADEPHIA, PA | $2,437,500 | 2026 | EDUCATION |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $1,741,666 | 2026 | MEDICAL RESEARCH |
| BETH ISRAEL DEACONESS MEDICAL CENTER | BOSTON, MA | $709,500 | 2026 | MEDICAL RESEARCH |
| PRESIDENT & FELLOWS OF HARVARD COLLEGE | BOSTON, MA | $635,097 | 2026 | MEDICAL RESEARCH |
| MASSACHUSETTS EYE AND EAR INFIRMARY | BOSTON, MA | $274,525 | 2026 | PUBLIC WELFARE |
| THE NEW YORK STEM CELL FOUNDATION | NEW YORK, NY | $272,300 | 2026 | EDUCATION |
| MASSACHUSETTS ADVOCATES FOR CHILDREN | BOSTON, MA | $160,000 | 2026 | MEDICAL RESEARCH |
| DANA FARBER CANCER INSITUTE | BROOKLINE, MA | $132,291 | 2026 | MEDICAL RESEARCH |
| RUTGERS UNIVERSITY | PISCATAWAY, NJ | $125,000 | 2026 | PUBLIC WELFARE |
| BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY | CARBONDALE, IL | $99,870 | 2026 | MEDICAL RESEARCH |
| MAX-PLANCK-INSTITUT FR BIOLOGISCHE INTELLIGENZ | MARTINSRIED | $75,000 | 2026 | MEDICAL RESEARCH |
| THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO | LOS ANGELES, CA | $75,000 | 2026 | PUBLIC WELFARE |
| NYU GROSSMAN SCHOOL OF MEDICINE | BOSTON, MA | $75,000 | 2026 | MEDICAL RESEARCH |
| YALE UNIVERSITY | NEW HAVEN, CT | $75,000 | 2026 | EDUCATION |
| UNIVERSITY OF CHICAGO | SUITE CHICAGO, IL | $75,000 | 2026 | EDUCATION |
| UNIVERSITY OF MASSACHUSETTS | NORTH WORCESTER, MA | $60,000 | 2026 | EDUCATION |
| BOSTON MEDICAL CENTER | BOSTON, MA | $51,846 | 2026 | MEDICAL RESEARCH |
| BOSTON SYMPHONY ORCHESTRA | BOSTON, MA | $40,000 | 2026 | PUBLIC WELFARE |
| NEW ENGLAND YACHAD | BROOKLINE, MA | $40,000 | 2026 | PUBLIC WELFARE |
| 3L PLACE | SOMERVILLE, MA | $25,000 | 2026 | PUBLIC WELFARE |
| BERKLEE INSTITUTE FOR ACCESSIBLE ARTS EDUCATION | BOSTON, MA | $20,000 | 2026 | EDUCATION |
| FRAXA RESEARCH FOUNDATION | WATERTOWN, MA | $15,000 | 2026 | PUBLIC WELFARE |
| AUTISM RESEARCH INSTITUTE | SAN DIEGO, CA | $12,500 | 2026 | MEDICAL RESEARCH |
| HOSPICE FOUNDATION OF AMERICA | SUITE WASHINGTON, DC | $12,242 | 2026 | MEDICAL RESEARCH |
| GORDON RESEARCH CONFERENCE (AMEX) | EAST GREENWICH, RI | $12,000 | 2026 | MEDICAL RESEARCH |
| HEBREW SENIOR LIFE | BOSTON, MA | $10,000 | 2026 | PUBLIC WELFARE |
| BOSTON HEALTH CARE FOR THE HOMELESS PROGRAM | BOSTON, MA | $10,000 | 2026 | PUBLIC WELFARE |
| JCC GREATER BOSTON | NEWTON, MA | $6,000 | 2026 | MEDICAL RESEARCH |
| UMASS CHAN MEDICAL SCHOOL OFFICE OF ADVANCEMENT | WORCESTER, MA | $2,500 | 2026 | MEDICAL RESEARCH |
| MERWIN MEMORIAL FREE CLINIC FOR ANIMALS INC | ALLSTON, MA | $400 | 2026 | PUBLIC WELFARE |
| HOLY CHIDHOOD | ROCHESTER, NY | $250 | 2026 | MEDICAL RESEARCH |
| PAN MASSACHUSETTS CHALLENGE INC - DANA FARBER | AVENUE NEEDHAM, MA | $250 | 2026 | MEDICAL RESEARCH |
| PROJECT BREAD | BOSTON, MA | $250 | 2026 | EDUCATION |
| CHARLES MOSESIAN CENTER FOR THE ARTS | WATERTOWN, MA | $125 | 2026 | MEDICAL RESEARCH |
| MSPCA-ANGELL | BOSTON, MA | $101 | 2026 | PUBLIC WELFARE |
| GREATER BOSTON LEGAL SERVICES | BOSTON, MA | $100 | 2026 | PUBLIC WELFARE |
| CAREDIMENSIONS | DANVERS, MA | $100 | 2026 | PUBLIC WELFARE |
| ALZHEIMER'S ASSOCIATION | CHICAGO, IL | $50 | 2026 | PUBLIC WELFARE |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $1,366,666 | 2025 | MEDICAL RESEARCH |
| LURIE FAMILY AUTISM CENTER CLINICAL PROGRAM FUND | LEXINGTON, MA | $1,000,000 | 2025 | MEDICAL RESEARCH |
| MASSACHUSETTS EYE AND EAR INFIRMARY | BOSTON, MA | $549,284 | 2025 | MEDICAL RESEARCH |
| PRESIDENT AND FELLOWS OF HARVARD COLLEGE | BOSTON, MA | $478,542 | 2025 | EDUCATION |
| MAINE MEDICAL CENTER | WESTBROOK, ME | $394,809 | 2025 | MEDICAL RESEARCH |
| BETH ISRAEL DEACONESS MEDICAL CENTER | BOSTON, MA | $353,500 | 2025 | MEDICAL RESEARCH |
| RUTGERS UNIVERSITY | PISCATAWAY, NJ | $250,000 | 2025 | EDUCATION |
| MASSACHUSETTS ADVOCATES FOR CHILDREN | BOSTON, MA | $160,000 | 2025 | PUBLIC WELFARE |
| DANA FARBER CANCER INSITUTE | BROOKLINE, MA | $93,708 | 2025 | MEDICAL RESEARCH |
| YALE UNIVERSITY | NEW HAVEN, CT | $75,000 | 2025 | EDUCATION |
| UNIVERSITY OF MASSACHUSETTS | NORTH WORCESTER, MA | $60,000 | 2025 | EDUCATION |
MASSACHUSETTS GENERAL HOSPITAL
$1,741,666MEDICAL RESEARCH
MASSACHUSETTS EYE AND EAR INFIRMARY
$274,525PUBLIC WELFARE
DANA FARBER CANCER INSITUTE
$132,291MEDICAL RESEARCH
RUTGERS UNIVERSITY
$125,000PUBLIC WELFARE
BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY
$99,870MEDICAL RESEARCH
MAX-PLANCK-INSTITUT FR BIOLOGISCHE INTELLIGENZ
$75,000MEDICAL RESEARCH
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$75,000PUBLIC WELFARE
NYU GROSSMAN SCHOOL OF MEDICINE
$75,000MEDICAL RESEARCH
YALE UNIVERSITY
$75,000EDUCATION
UNIVERSITY OF MASSACHUSETTS
$60,000EDUCATION
BOSTON SYMPHONY ORCHESTRA
$40,000PUBLIC WELFARE
NEW ENGLAND YACHAD
$40,000PUBLIC WELFARE
3L PLACE
$25,000PUBLIC WELFARE
BERKLEE INSTITUTE FOR ACCESSIBLE ARTS EDUCATION
$20,000EDUCATION
HOSPICE FOUNDATION OF AMERICA
$12,242MEDICAL RESEARCH
GORDON RESEARCH CONFERENCE (AMEX)
$12,000MEDICAL RESEARCH
HEBREW SENIOR LIFE
$10,000PUBLIC WELFARE
JCC GREATER BOSTON
$6,000MEDICAL RESEARCH
UMASS CHAN MEDICAL SCHOOL OFFICE OF ADVANCEMENT
$2,500MEDICAL RESEARCH
MERWIN MEMORIAL FREE CLINIC FOR ANIMALS INC
$400PUBLIC WELFARE
HOLY CHIDHOOD
$250MEDICAL RESEARCH
CHARLES MOSESIAN CENTER FOR THE ARTS
$125MEDICAL RESEARCH
MASSACHUSETTS GENERAL HOSPITAL
$1,366,666MEDICAL RESEARCH
LURIE FAMILY AUTISM CENTER CLINICAL PROGRAM FUND
$1,000,000MEDICAL RESEARCH
MASSACHUSETTS EYE AND EAR INFIRMARY
$549,284MEDICAL RESEARCH
MAINE MEDICAL CENTER
$394,809MEDICAL RESEARCH
RUTGERS UNIVERSITY
$250,000EDUCATION
DANA FARBER CANCER INSITUTE
$93,708MEDICAL RESEARCH
YALE UNIVERSITY
$75,000EDUCATION
UNIVERSITY OF MASSACHUSETTS
$60,000EDUCATION