| SEVEN BRIDGES GENOMICS INC (VELSERA) | CHARLESTOWN, MA | $412,225 | 2025 | EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DEVELOP INTEGRATION BETWEEN SAGE'S DATA SHARING PORTAL, SYNAPSE, AND CABATICA. |
| Institute for Systems Biology | Seattle, WA | $379,595 | 2025 | CRI Immune Atlas4: Platform for immune-oncology research and data sharing. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them. |
| PENNSYLVANIA STATE UNIVERSITY | UNIVERSITY PARK, PA | $251,814 | 2025 | PHASE 1 AND 2: RECOVER MOBILE HEALTH PLATFORM/MOBILE HEALTH REPOSITORIES WORKING GROUP: DEVELOP PROCESS FOR MHP TO COLLECT PASC RELATED MOBILE HEALTH DATA FROM PARTICIPANTS AND SHARE THIS DATA WITH MHDR TO CLEAN CURATE, CONDUCT QA/QC, STORE AND PROVIDE ACCESS TO RESEARCHERS. CUSTOMIZATION OF THE MOBILE HEALTH PLATFORM, IMPLEMENTATION OF MOBILE DATA COLLECTION AMONG THE VARIOUS STUDIES, AS WELL AS, THE STORING, CURATION, LINKAGE, AND ANALYSES OF THE MOBILE HEALTH DATA. |
| University of California Los Angeles | Los Angeles, CA | $208,563 | 2025 | ITCR, lead evaluation and testing of new Synapse features and their incorporation into multiple challenges, including a lead study of prostate cancer Active Surveillance. Provide strategic advice, feature-testing and development, usage-scenarios and intensive testing. |
| Memorial Sloan-Kettering Cancer Center | New York, NY | $204,479 | 2025 | Perform all work related to the proposed BRCA Pre-Cancer Atlas instance of the cBioPortal for Cancer Genomics. Build, maintain and run automated pipelines that transfer data from Synapse into BRCA Pre-Cancer Atlas Data Portal. Maintain all user logins and develop new Data Portal and cBioPortal features as they become relevant for the project. Provide user support, documentation, and outreach for the entire BRCA Pre Cancer Atlas. |
| INSTITUTE FOR SYSTEMS BIOLOGY | SEATTLE, WA | $204,222 | 2025 | CRI IMMUNE ATLAS 4 AND 5: PLATFORM FOR IMMUNE-ONCOLOGY RESEARCH AND DATA SHARING. EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DESIGN AND PERFORM CROSS-PROJECT ANALYSIS FOCUSED ON HARNESSING SYSTEMS BIOLOGY-BASED TECHNIQUES, SUCH AS MULTI-OMIC DATA INTEGRATION, NETWORK ANALYSIS, MACHINE LEARNING, AND STATISTICAL MODELING, TO INVESTIGATE BOTH AGING AND DISEASE, AS WELL AS THE INTERPLAY BETWEEN THEM. |
| Duke University | Durham, NC | $203,859 | 2025 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| Seven Bridges Genomics Inc | Boston, MA | $199,853 | 2025 | Exceptional Longevity Data Management and Coordinating Center, develop integration between Sage's data sharing portal, Synapse, and CABATICA. |
| Pennsylvania State University | University Park, PA | $194,842 | 2025 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | CHAPEL HILL, NC | $169,611 | 2025 | CRI IMMUNE ATLAS 4 AND 5: PLATFORM FOR IMMUNE-ONCOLOGY RESEARCH AND DATA SHARING. DEFINING REGRESSION MODELS AND VALIDATION METHODS FOR USE IN IMPLEMENTING STATISTICAL LEARNING MODELS FOR BIOMARKER DEVELOPMENT IN IATLAS. ADD COMPREHENSIVE TUMOR ANTIGEN PREDICTION FROM MULTIPLE GENOMIC SOURCES TO IATLAS DATASETS. HARMONIZE AND CURATE DATA FROM ADDITIONAL IO CLINICAL TRIALS WITH GENOMIC DATA FOR ANALYSIS USING THE IO RESPONSE MODULE. |
| Harvard Office of Sponsored Programs | Boston, MA | $164,066 | 2025 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |
| University of North Carolina at Chapel Hill | Chapel Hill, NC | $163,934 | 2025 | CRI Immune Atlas4: Platform for immune-oncology research and data sharing. Defining regression models and validation methods for use in implementing statistical learning models for biomarker development in iAtlas. Add comprehensive tumor antigen prediction from multiple genomic sources to iAtlas datasets. Harmonize and curate data from additional IO clinical trials with genomic data for analysis using the IO response module. |
| HARVARD OFFICE OF SPONSORED PROGRAMS | BOSTON, MA | $156,432 | 2025 | MULTI-CONSORTIA COORDINATING CENTER (MC2 CENTER) FOR CANCER BIOLOGY: BUILDING INTERDISCIPLINARY SCIENTIFIC COMMUNITIES, COORDINATING IMPACTFUL RESOURCE SHARING, AND ADVANCING CANCER RESEARCH. |
| Translational Genomics Research Institute | Phoenix, AZ | $154,554 | 2025 | Exceptional Longevity Data Management and Coordinating Center, develop analytical methods for accommodating and exploring heterogeneity in large aggregated databases. They will also apply these methods with the other investigators as well as researchers associated with the consortia that generated the aggregated data. |
| MEMORIAL SLOAN-KETTERING CANCER CENTER | NEW YORK, NY | $136,319 | 2025 | PERFORM ALL WORK RELATED TO THE PROPOSED BRCA PRE-CANCER ATLAS INSTANCE OF THE CBIOPORTAL FOR CANCER GENOMICS. BUILD, MAINTAIN AND RUN AUTOMATED PIPELINES THAT TRANSFER DATA FROM SYNAPSE INTO BRCA PRE-CANCER ATLAS DATA PORTAL. MAINTAIN ALL USER LOGINS AND DEVELOP NEW DATA PORTAL AND CBIOPORTAL FEATURES AS THEY BECOME RELEVANT FOR THE PROJECT. PROVIDE USER SUPPORT, DOCUMENTATION, AND OUTREACH FOR THE ENTIRE BRCA PRE CANCER ATLAS. |
| EMORY UNIVERSITY | ATLANTA, GA | $125,000 | 2025 | MULTI-CONSORTIA COORDINATING CENTER (MC2 CETNER) FOR CANCER BIOLOGY: DEVELOP AND APPL QUALITY CONTROL WORKFLOWS TO ENSURE AI/ML-READINESS OF DIGITAL PATHOLOGY ACROSS MULTI-OMIC DATASETS, WITH CONTRIBUTIONS TO TOOL DEVELOPMENT, METRIC DEFINITION, EXPERIMENTAL DESIGN, AND COLLABORATIVE STUDY OVERSIGHT. |
| INSTITUTE FOR SYSTEMS BIOLOGY | SEATTLE, WA | $114,897 | 2025 | EXCEPTIONAL LONGEVITY: PROVIDE SCIENTIFIC OVERSIGHT OF A WORKING GROUP CONDUCTING CROSS-PROJECT ANALYSES USING SYSTEMS BIOLOGY APPROACHES TO STUDY AGING, ALZHEIMERS DISEASE, AND THEIR INTERACTIONS. |
| DUKE UNIVERSITY | DURHAM, NC | $103,680 | 2025 | PHASE 1 AND 2: RECOVER MOBILE HEALTH PLATFORM/MOBILE HEALTH REPOSITORIES WORKING GROUP: DEVELOP PROCESS FOR MHP TO COLLECT PASC RELATED MOBILE HEALTH DATA FROM PARTICIPANTS AND SHARE THIS DATA WITH MHDR TO CLEAN CURATE, CONDUCT QA/QC, STORE AND PROVIDE ACCESS TO RESEARCHERS. CUSTOMIZATION OF THE MOBILE HEALTH PLATFORM, IMPLEMENTATION OF MOBILE DATA COLLECTION AMONG THE VARIOUS STUDIES, AS WELL AS, THE STORING, CURATION, LINKAGE, AND ANALYSES OF THE MOBILE HEALTH DATA. |
| Yale University | New Haven, CT | $102,541 | 2025 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |
| TUFTS MEDICAL CENTER | BOSTON, MA | $80,688 | 2025 | EXCEPTIONAL LONGEVITY: SUPPORT DATA HARMONIZATION AND ANALYSIS FOR LONGEVITY RESEARCH, INCLUDING COLLABORATION ON A SYNTHETIC DATA CHALLENGE, WITH RESPONSIBILITIES FOR PROJECT OVERSIGHT, DATA PREPARATION, EVALUATION, AND REPORTING. |
| UNIVERSITY OF CALIFORNIA LOS ANGELES | LOS ANGELES, CA | $78,426 | 2025 | ITCR, LEAD EVALUATION AND TESTING OF NEW SYNAPSE FEATURES AND THEIR INCORPORATION INTO MULTIPLE CHALLENGES, INCLUDING A LEAD STUDY OF PROSTATE CANCER ACTIVE SURVEILLANCE. PROVIDE STRATEGIC ADVICE, FEATURE-TESTING AND DEVELOPMENT, USAGE-SCENARIOS AND INTENSIVE TESTING. |
| University of Winsconsin-Madison | Madison, WI | $71,103 | 2025 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |
| YALE UNIVERSITY | NEW HAVEN, CT | $70,420 | 2025 | MULTI-CONSORTIA COORDINATING CENTER (MC2 CENTER) FOR CANCER BIOLOGY: BUILDING INTERDISCIPLINARY SCIENTIFIC COMMUNITIES, COORDINATING IMPACTFUL RESOURCE SHARING, AND ADVANCING CANCER RESEARCH. |
| TRANSLATIONAL GENOMICS RESEARCH INSTITUTE | PHOENIX, AZ | $68,791 | 2025 | EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DEVELOP ANALYTICAL METHODS FOR ACCOMMODATING AND EXPLORING HETEROGENEITY IN LARGE AGGREGATED DATABASES. THEY WILL ALSO APPLY THESE METHODS WITH THE OTHER INVESTIGATORS AS WELL AS RESEARCHERS ASSOCIATED WITH THE CONSORTIA THAT GENERATED THE AGGREGATED DATA. |
| STANFORD UNIVERSITY | STANFORD, CA | $50,000 | 2025 | MULTI-CONSORTIA COORDINATING CENTER (MC2 CENTER) FOR CANCER BIOLOGY: WORK WITH SAGE TO DEVELOP A PILOT WEB APPLICATION FOR EXPLORING SPATIAL TRANSCRIPTOMIC DATA IN CANCER RESEARCH. |
| UNIVERSITY OF WASHINGTON | SEATTLE, WA | $36,580 | 2025 | AMP AD KNOWLEDGE PORTAL: BUILD INTEROPERABILITY BETWEEN TWO MAJOR ALZHEIMER'S RESEARCH PLATFORMS BY CREATING BIDIRECTIONAL METADATA FLOWS, ENABLING RESEARCHERS TO DISCOVER AND ACCESS MULTI-OMIC, MICROBIOME, IMAGING, AND CLINICAL DATASETS ACROSS SYSTEMS THROUGH INTEGRATED TOOLS, AUTOMATED REQUESTS, AND ENHANCED COHORT SELECTION CAPABILITIES. |
| University of Colorado Denver | Denver, CO | $23,919 | 2025 | Provide support for governance issues and regulatory coordination with NIH, providing technical management support for project teams, training and coordination for sites to participate in analytical activities, and support for public relations and dissemination of research outcomes for the COVID 19 Cohort Collaborative for Disease Modeling project. |
| UNIVERSITY OF COLORADO DENVER | DENVER, CO | $13,649 | 2025 | PROVIDE SUPPORT FOR GOVERNANCE ISSUES AND REGULATORY COORDINATION WITH NIH, PROVIDING TECHNICAL MANAGEMENT SUPPORT FOR PROJECT TEAMS, TRAINING AND COORDINATION FOR SITES TO PARTICIPATE IN ANALYTICAL ACTIVITIES, AND SUPPORT FOR PUBLIC RELATIONS AND DISSEMINATION OF RESEARCH OUTCOMES FOR THE COVID 19 COHORT COLLABORATIVE FOR DISEASE MODELING PROJECT. |
| THE BROAD INSTITUTE | CAMBRIDGE, MA | $6,757 | 2025 | AMP AD KNOWLEDGE PORTAL: EXTEND THE ALZHEIMER'S DISEASE DATA COORDINATION CENTER BY INTEGRATING SAGE-HOSTED DATA WITH THE TERRA PLATFORM, ENABLING SECURE ACCOUNT LINKING, DATA ACCESS, AND SYNTHETIC COHORT HANDOFFS, WITH ONGOING TECHNICAL UPDATES AND CROSS-TEAM COORDINATION OVER THE AWARD PERIOD. |
| University of California San Francisco | San Francisco, CA | $5,313 | 2025 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| Institute for Systems Biology | Seattle, WA | $289,400 | 2023 | CRI Immune Atlas: Platform for immune-oncology research and data sharing phase 2 and 3. Exceptional Longevity Data Management and Coordinating Center, design and perform cross-project analysis focused on harnessing systems biology-based techniques, such as multi-omic data integration, network analysis, machine learning, and statistical modeling, to investigate both aging and disease, as well as the interplay between them. |
| University of North Carolina at Chapel Hill | Chapel Hill, NC | $152,381 | 2023 | CRI Immune Atlas: Platform for immune-oncology research and data sharing phase 2 and 3. Defining regression models and validation methods for use in implementing statistical learning models for biomarker development in iAtlas. Add comprehensive tumor antigen prediction from multiple genomic sources to iAtlas datasets. Harmonize and curate data from additional IO clinical trials with genomic data for analysis using the IO response module. |
| University of Washington | Seattle, WA | $152,021 | 2023 | Partner to prototype and test best ways to build a Global Mental Health Databank that holds rich longitudinal data at scale from different global locations on approaches, treatments and interventions potentially relevant to anxiety or depression in 14-24 year olds. |
| University of California Los Angeles | Los Angeles, CA | $114,295 | 2023 | Lead evaluation and testing of new Synapse features and their incorporation into multiple challenges, including a lead study of prostate cancer Active Surveillance. Provide strategic advice, feature-testing and development, usage-scenarios and intensive testing. |
| Memorial Sloan Kettering Cancer Center | New York, NY | $89,636 | 2023 | Perform all work related to the proposed BRCA Pre-Cancer Atlas instance of the cBioPortal for Cancer Genomics. Build, maintain and run automated pipelines that transfer data from Synapse into BRCA Pre-Cancer Atlas Data Portal. Maintain all user logins and develop new Data Portal and cBioPortal features as they become relevant for the project. Provide user support, documentation, and outreach for the entire BRCA Pre Cancer Atlas. |
| Duke University | Durham, NC | $62,628 | 2023 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| Seven Bridges Genomics Inc | Boston, MA | $55,257 | 2023 | Exceptional Longevity Data Management and Coordinating Center, develop integration between Sage's data sharing portal, Synapse, and CABATICA. |
| Harvard University Medical School | Boston, MA | $43,998 | 2023 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |
| Translational Genomics Research Institute | Phoenix, AZ | $42,329 | 2023 | Exceptional Longevity Data Management and Coordinating Center, develop analytical methods for accommodating and exploring heterogeneity in large aggregated databases. They will also apply these methods with the other invetigators as well as researchers associated with the consortia that generated the aggregated data. |
| The Pennsylvania State University | University Park, PA | $42,315 | 2023 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| Yale University | New Haven, CT | $37,046 | 2023 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |
| OCHIN Inc | Portland, OR | $34,922 | 2023 | As part of OCHIN's participation in the N3C Network, regulatory/compliance requirements, execute Data Transfer Agreement between OCHIN and NCATS, execute a reliance agreement on the approved Johns Hopkins IRB. |
| University of California San Francisco | San Francisco, CA | $31,464 | 2023 | Phase 1 and 2: RECOVER Mobile Health Platform/Mobile Health Repositories Working Group: Develop process for MHP to collect PASC related mobile health data from participants and share this data with MHDR to clean curate, conduct QA/QC, store and provide access to researchers. Customization of the mobile health platform, implementation of mobile data collection among the various studies, as well as, the storing, curation, linkage, and analyses of the mobile health data. |
| University of Colorado Denver | Denver, CO | $23,528 | 2023 | Provide support for governance issues and regulatory coordination with NIH, providing technical management support for project teams, training and coordination for sites to participate in analytical activities, and support for public relations and dissemination of research outcomes for the COVID 19 Cohort Collaborative for Disease Modeling project. |
| Mayo Clinic | Rochester, MN | $16,797 | 2023 | Enhance natural language processing capabilities across CTSA institutions through community engagement and accelerate the use of clinical narratives for rapid COVID-19 clinical research through team science collaboration. |
| University of Wisconsin Madison | Madison, WI | $5,861 | 2023 | Multi-Consortia Coordinating Center (MC2 Center) for Cancer Biology: Building Interdisciplinary Scientific Communities, Coordinating Impactful Resource Sharing, and Advancing Cancer Research. |