Connecting our community’s generosity to a healthier tomorrow for all.
Prisma Health’s largest recent grant went to USC School of Medicine Greenville, with $36,516,044 in 2023 for operational and community engagement support. That single award signals a grantmaker that uses philanthropy to strengthen health-related institutions and the systems around them, especially in South Carolina. Across its recent grants, the foundation backs medical education, community health infrastructure, and services tied to behavioral health, cancer care and research, pediatrics, rehabilitation, women’s health, and patient support programs. The giving pattern also shows a strong connection to local partners in Greenville, Columbia, Spartanburg, Sumter, Greenwood, and Seneca. Prisma Health has made large commitments to medical education entities such as USC School of Medicine, USC School of Medicine Greenville, and USC Upstate Foundation, while also supporting community-facing organizations like the Community Foundation of Greenville, Greenville Technical College, and Well Partners Dental and Eye Health. The presence of hospitals, colleges, museums, and local service organizations points to a funder that blends health-sector investment with broader community engagement. Most grants are directed within South Carolina, aligning philanthropy closely with the communities it serves.
Medical education and training are a major theme. Prisma Health gave $24,007,500 in 2025 to USC School of Medicine for operational and community engagement support, and $1,500,000 in 2024 to Greenville Technical College for the same purpose. It also supported USC Upstate Foundation with $2,600,000 in 2023 and USC Educational Foundation with $1,300,000 in 2023. Community health access appears alongside education. In Columbia, the foundation awarded $345,000 in 2025 to Well Partners Dental and Eye Health and $200,000 in 2025 to City Of Columbia for op/community engagement. It also made repeated support to Eau Claire Cooperative Health Center Inc, including $200,000 in 2025, and to County Of Greenville, including $247,596 in 2024. Children’s and family-serving organizations also receive support. Grants include $200,000 in 2024 to SC Children’s Theatre, $150,000 in 2024 to EdVenture Children’s Museum, and $101,800 in 2025 to A Child’s Haven.
Prisma Health’s typical grant size sits at $10,000 at the 25th percentile, $17,500 at the median, and $35,312 at the 75th percentile, even as a handful of large awards lift overall annual giving. The pattern includes repeat support to the same recipients across multiple years, such as USC School of Medicine Greenville in 2023 and 2024 and EAU Claire Cooperative Health Center across 2023 through 2025. The foundation is an operating grantmaker rather than an individual-giving funder, and it does not make program-related investments. Its recent grants are labeled mainly as operational/community engagement support, indicating flexible institutional support rather than narrowly restricted project funding.
$43.3M
$4.6B
$339.5M
$159.5M
Most grants fall between $10K and $35K, with a median of $18K.
25th Percentile
$10K
Median
$18K
75th Percentile
$35K
Mark S O'Halla
President and CEO of Prisma Health
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Prisma Health’s grantmaking is overwhelmingly South Carolina-focused: 97% of grants go to recipients in the HQ state, and the top giving state is SC. Recent awards cluster in Greenville and Columbia, with additional grants in Spartanburg, Sumter, Greenwood, Seneca, and Taylors. Greenville appears frequently through recipients such as Greenville Technical College, the Community Foundation of Greenville, and County Of Greenville, while Columbia shows up through USC Educational Foundation, Midlands Tech Coll Foundation, and City Of Columbia. All recent grants in the dataset went to US recipients.
Recent grants go to medical schools, technical colleges, community health centers, local nonprofits, and public-serving institutions. Examples in the data include USC School of Medicine Greenville, Greenville Technical College, Eau Claire Cooperative Health Center Inc, and Community Foundation of Greenville, usually for operational or community engagement support.
The listed focus areas are behavioral health, cancer care and research, pediatrics and children's services, medical education and scholarships, rehabilitation, women's health, and patient support programs. The recent grants reflect that mix, especially through medical education and community health access.
Yes. 97% of grants go to recipients in South Carolina, and SC is the top state by grant count. The recent grants list is entirely US-based, with South Carolina cities including Greenville, Columbia, Spartanburg, Sumter, Greenwood, Seneca, and Taylors.
The typical grant size is $10,000 at the 25th percentile, $17,500 at the median, and $35,312 at the 75th percentile. Recent giving also includes several much larger institutional awards, especially for medical education and community engagement support.
Yes. USC School of Medicine Greenville appears in 2023 and 2024, USC School of Medicine appears in 2025, and EAU Claire Cooperative Health Center Inc appears in 2023, 2024, and 2025. The repeat pattern suggests ongoing support for some institutions rather than one-time gifts only.
2026
Source: IRS Form 990-PF, fiscal year 2026.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| USC SCHOOL OF MEDICINE | GREENVILLE, SC | $38,700,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| PRISMA HEALTH-UPSTATE FOUNDATION | GREENVILLE, SC | $1,824,061 | 2026 | OP/COMMUNITY ENGAGEMENT |
| TUOMEY FOUNDATION | SUMTER, SC | $469,470 | 2026 | OP/COMMUNITY ENGAGEMENT |
| UNITED WAY OF THE MIDLANDS | COLUMBIA, SC | $360,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| CITY OF COLUMBIA | COLUMBIA, SC | $200,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| GREENVILLE COUNTY REC | TAYLORS, SC | $150,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| COUNTY OF GREENVILLE | GREENVILLE, SC | $125,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SC CHILDREN'S THEATRE | GREENVILLE, SC | $100,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| ARTISPHERE | GREENVILLE, SC | $90,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| MENTAL ILLNESS RECOVERY CENTER | COLUMBIA, SC | $90,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| GREENVILLE CHAMBER OF COMMERCE | GREENVILLE, SC | $82,800 | 2026 | OP/COMMUNITY ENGAGEMENT |
| HEALTHTEACHER INC | PASADENA, CA | $70,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SC RESEARCH FOUNDATION | COLUMBIA, SC | $50,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| NAMI GREENVILLE SC | GREENVILLE, SC | $50,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| JAMES R CLARK SICKLE CELL FOUNDATION | COLUMBIA, SC | $40,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| MARCH OF DIMES | GREENVILLE, SC | $31,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| CITY CENTER PARTNERSHIP INC | COLUMBIA, SC | $30,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SAMARITAN HEALTH CLINIC OF | EASLEY, SC | $30,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| BLACK PAGES INTERNATIONAL | GREENVILLE, SC | $30,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| MEDNEED OF SC | COLUMBIA, SC | $30,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| PATHWAYS TO HEALING | COLUMBIA, SC | $30,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| GREENVILLE TECH FOUNDATION INC | GREENVILLE, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| COLUMBIA URBAN LEAGUE | COLUMBIA, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| UNCF UPSTATE | GREENVILLE, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| NOTUS SPORTS | GREENVILLE, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| USC EDUCATIONAL FOUNDATION | COLUMBIA, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| GREATER COLUMBIA CHAMBER OF COMMERCE | COLUMBIA, SC | $25,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SC CHAMBER OF COMMERCE | COLUMBIA, SC | $24,489 | 2026 | OP/COMMUNITY ENGAGEMENT |
| LIVEWELL GREENVILLE | GREENVILLE, SC | $20,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| JULIE VALENTINE CENTER | GREENVILLE, SC | $20,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| THE GOOD SAMARITAN CLINIC | LEXINGTON, SC | $20,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| FEONIX-MOBILITY RISING | LINCOLN, NE | $20,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| GREENVILLE ZOO | GREENVILLE, SC | $20,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| AHA ECC DISTRIBUTION | MT PLEASANT, SC | $17,500 | 2026 | OP/COMMUNITY ENGAGEMENT |
| CITY OF GREENVILLE SC | GREENVILLE, SC | $17,500 | 2026 | OP/COMMUNITY ENGAGEMENT |
| RIVERBANKS ZOO | COLUMBIA, SC | $17,500 | 2026 | OP/COMMUNITY ENGAGEMENT |
| FURMAN UNIVERSITY | GREENVILLE, SC | $16,600 | 2026 | OP/COMMUNITY ENGAGEMENT |
| CENTRAL SC ALLIANCE | COLUMBIA, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| CHARITY BALL BOARD OF GREENVILLE | GREENVILLE, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SOUTH CAROLINA LEGISLATIVE BLACK CAUCUS INC | COLUMBIA, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| FAVOR UPSTATE | GREENVILLE, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| LEXINGTON CHAMBER OF COMMERCE | LEXINGTON, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| BREAKTHROUGH T1D | NEW YORK, NY | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SC PHILHARMONIC INC | COLUMBIA, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| OUR UPSTATE | GREENVILLE, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| HISPANIC ALLIANCE | GREENVILLE, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| FAMILY CONNECTION OF SC | COLUMBIA, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| PINK & GREEN COMMUNITY SERVICE FOUNDATION INC | COLUMBIA, SC | $15,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
| LAURENS CO CHAMBER OF COMMERCE | GREENVILLE, SC | $11,500 | 2026 | OP/COMMUNITY ENGAGEMENT |
| SENIOR RESOURCES INC | COLUMBIA, SC | $10,000 | 2026 | OP/COMMUNITY ENGAGEMENT |
PRISMA HEALTH-UPSTATE FOUNDATION
$1,824,061OP/COMMUNITY ENGAGEMENT
TUOMEY FOUNDATION
$469,470OP/COMMUNITY ENGAGEMENT
CITY OF COLUMBIA
$200,000OP/COMMUNITY ENGAGEMENT
GREENVILLE COUNTY REC
$150,000OP/COMMUNITY ENGAGEMENT
COUNTY OF GREENVILLE
$125,000OP/COMMUNITY ENGAGEMENT
GREENVILLE CHAMBER OF COMMERCE
$82,800OP/COMMUNITY ENGAGEMENT
HEALTHTEACHER INC
$70,000OP/COMMUNITY ENGAGEMENT
SC RESEARCH FOUNDATION
$50,000OP/COMMUNITY ENGAGEMENT
NAMI GREENVILLE SC
$50,000OP/COMMUNITY ENGAGEMENT
JAMES R CLARK SICKLE CELL FOUNDATION
$40,000OP/COMMUNITY ENGAGEMENT
CITY CENTER PARTNERSHIP INC
$30,000OP/COMMUNITY ENGAGEMENT
SAMARITAN HEALTH CLINIC OF
$30,000OP/COMMUNITY ENGAGEMENT
BLACK PAGES INTERNATIONAL
$30,000OP/COMMUNITY ENGAGEMENT
MEDNEED OF SC
$30,000OP/COMMUNITY ENGAGEMENT
PATHWAYS TO HEALING
$30,000OP/COMMUNITY ENGAGEMENT
NOTUS SPORTS
$25,000OP/COMMUNITY ENGAGEMENT
GREATER COLUMBIA CHAMBER OF COMMERCE
$25,000OP/COMMUNITY ENGAGEMENT
SC CHAMBER OF COMMERCE
$24,489OP/COMMUNITY ENGAGEMENT
THE GOOD SAMARITAN CLINIC
$20,000OP/COMMUNITY ENGAGEMENT
GREENVILLE ZOO
$20,000OP/COMMUNITY ENGAGEMENT
CITY OF GREENVILLE SC
$17,500OP/COMMUNITY ENGAGEMENT
RIVERBANKS ZOO
$17,500OP/COMMUNITY ENGAGEMENT
CENTRAL SC ALLIANCE
$15,000OP/COMMUNITY ENGAGEMENT
CHARITY BALL BOARD OF GREENVILLE
$15,000OP/COMMUNITY ENGAGEMENT
SOUTH CAROLINA LEGISLATIVE BLACK CAUCUS INC
$15,000OP/COMMUNITY ENGAGEMENT
LEXINGTON CHAMBER OF COMMERCE
$15,000OP/COMMUNITY ENGAGEMENT
SC PHILHARMONIC INC
$15,000OP/COMMUNITY ENGAGEMENT
OUR UPSTATE
$15,000OP/COMMUNITY ENGAGEMENT
PINK & GREEN COMMUNITY SERVICE FOUNDATION INC
$15,000OP/COMMUNITY ENGAGEMENT
LAURENS CO CHAMBER OF COMMERCE
$11,500OP/COMMUNITY ENGAGEMENT
SENIOR RESOURCES INC
$10,000OP/COMMUNITY ENGAGEMENT