About Prisma Health
Connecting our community’s generosity to a healthier tomorrow for all.
Focus Areas
Behavioral healthCancer care and researchPediatrics and children's servicesMedical education and scholarshipsRehabilitationWomen's healthPatient support programs
Who They Fund
local communities / residentscommunity-based nonprofit organizationscivic or grassroots groups
Funding Style
operational support / general operatingcapacity building for operations
About Prisma Health
Prisma Health’s largest recent grant went to USC School of Medicine Greenville, with $36,516,044 in 2023 for operational and community engagement support. That single award signals a grantmaker that uses philanthropy to strengthen health-related institutions and the systems around them, especially in South Carolina. Across its recent grants, the foundation backs medical education, community health infrastructure, and services tied to behavioral health, cancer care and research, pediatrics, rehabilitation, women’s health, and patient support programs. The giving pattern also shows a strong connection to local partners in Greenville, Columbia, Spartanburg, Sumter, Greenwood, and Seneca. Prisma Health has made large commitments to medical education entities such as USC School of Medicine, USC School of Medicine Greenville, and USC Upstate Foundation, while also supporting community-facing organizations like the Community Foundation of Greenville, Greenville Technical College, and Well Partners Dental and Eye Health. The presence of hospitals, colleges, museums, and local service organizations points to a funder that blends health-sector investment with broader community engagement. Most grants are directed within South Carolina, aligning philanthropy closely with the communities it serves.
What Prisma Health Funds
Medical education and training are a major theme. Prisma Health gave $24,007,500 in 2025 to USC School of Medicine for operational and community engagement support, and $1,500,000 in 2024 to Greenville Technical College for the same purpose. It also supported USC Upstate Foundation with $2,600,000 in 2023 and USC Educational Foundation with $1,300,000 in 2023. Community health access appears alongside education. In Columbia, the foundation awarded $345,000 in 2025 to Well Partners Dental and Eye Health and $200,000 in 2025 to City Of Columbia for op/community engagement. It also made repeated support to Eau Claire Cooperative Health Center Inc, including $200,000 in 2025, and to County Of Greenville, including $247,596 in 2024. Children’s and family-serving organizations also receive support. Grants include $200,000 in 2024 to SC Children’s Theatre, $150,000 in 2024 to EdVenture Children’s Museum, and $101,800 in 2025 to A Child’s Haven.
How Prisma Health Gives
Prisma Health’s typical grant size sits at $10,000 at the 25th percentile, $17,500 at the median, and $35,312 at the 75th percentile, even as a handful of large awards lift overall annual giving. The pattern includes repeat support to the same recipients across multiple years, such as USC School of Medicine Greenville in 2023 and 2024 and EAU Claire Cooperative Health Center across 2023 through 2025. The foundation is an operating grantmaker rather than an individual-giving funder, and it does not make program-related investments. Its recent grants are labeled mainly as operational/community engagement support, indicating flexible institutional support rather than narrowly restricted project funding.
Financial Snapshot
Annual Giving
$31.5M
Total Assets
$3.8B
Total Revenue
$136.6M
Total Expenses
$111.6M
Typical Grant Size
Most grants fall between $10K and $35K, with a median of $18K.
25th Percentile
$10K
Median
$18K
75th Percentile
$35K
Geographic Reach
Local6 states funded
About 97% of grants go to recipients in SC.
Funding intensity
LowHigh
Headquarters
Leadership
Mark S O'Halla
President and CEO of Prisma Health
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