About Polybio Research Foundation
To deliver treatments to millions of Long COVID patients by translating academic findings into validated diagnostics, faster targeted clinical trials, and accessible patient-ready therapies; accelerate diagnostics, commercialization, and clinical adoption for Long COVID and related infection-driven chronic conditions.
Focus Areas
Long COVID researchPathogen persistenceDiagnostics validation and commercializationClinical trials for antivirals and immunotherapiesRelated chronic conditions (ME/CFS, Chronic Lyme)
Who They Fund
individual researchersuniversities/academic institutionsresearch institutes/laboratories
Funding Style
research-focused fundingproject-specific/restricted support
About Polybio Research Foundation
Polybio Research Foundation Inc centers its grantmaking on translating academic findings into patient-ready tools for Long COVID and related infection-driven chronic conditions. The largest recent award in the record is $5,078,544 to University of California San Francisco for research, followed by $3,503,518 to Icahn School of Medicine at Mount Sinai and $3,342,539 to Mass General Brigham. Those awards point to a research portfolio built around large scientific institutions working on evidence generation, diagnostics, and clinical adoption. The foundation’s stated aim is to deliver treatments to millions of Long COVID patients by moving from academic research to validated diagnostics, faster targeted clinical trials, and accessible therapies. Its recent grantees include universities, medical schools, hospitals, and research institutes, with repeated support for major biomedical centers such as the University of Pennsylvania School of Medicine, J Craig Venter Institute, and Yale. The grant list also shows support for individual researchers through its funding model. Recent awards range from major multi-million-dollar research grants to smaller project awards, all within a scientific, disease-focused portfolio. The record shows work across Long COVID research, pathogen persistence, diagnostics validation and commercialization, clinical trials for antivirals and immunotherapies, and related chronic conditions including ME/CFS and Chronic Lyme.
What Polybio Research Foundation Funds
A defining theme in the portfolio is translational research on Long COVID. Polybio Research Foundation Inc gave $2,091,756 to University of Pennsylvania School of Medicine for research grant work and $999,812 to NYU Grossman School of Medicine for research, both within a broader effort to move findings toward clinical use. Pathogen persistence is another clear emphasis. The foundation awarded $2,091,632 to J Craig Venter Institute Inc for research and later gave $290,025 to J Craig Venter Institute for a research grant, indicating continued support for that line of inquiry. It also backs diagnostics and commercialization work. One grant of $201,000 went to Stratevi LLC for a research grant, while $159,128 supported Amici Lovanienses for a research grant. Beyond that, the portfolio includes clinical research capacity at Georgetown University and University of Texas Southwestern, consistent with its interest in trials and clinical adoption.
Financial Snapshot
Annual Giving
$11.9M
Total Assets
$9.8M
Total Revenue
$4.3M
Total Expenses
$14.1M
Typical Grant Size
Most grants fall between $122K and $1.7M, with a median of $315K.
25th Percentile
$122K
Median
$315K
75th Percentile
$1.7M
Geographic Reach
National12 states funded
About 19% of grants go to recipients in CA.
Funding intensity
LowHigh
Headquarters
Leadership
AMY PROAL
Accepts unsolicited proposals
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