P-Squared Philanthropies concentrates on funding biomedical research and reproductive equity initiatives, with a clear emphasis on establishing and supporting specialized research centers (notably in neuroinflammation and metabolic psychiatry). Their grants go to major academic medical centers and intermediaries that manage research prize/funding mechanisms, indicating a preference for translating scientific discovery into structured research programs. They also use donor-advised/charitable-fund vehicles and philanthropic intermediaries to deploy large, strategic gifts.
P-Squared Philanthropies Inc has made seven-figure commitments to build named research centers, including $1,000,000 grants to New York University in both 2025 and 2023 for The Parekh Family Center for Neuroinflammation. That pattern points to a funder that supports specialized biomedical research infrastructure, not just isolated projects. Alongside the neuroinflammation center, the foundation backed the Parekh Metabolic Psychiatry Research Fund at Stanford with $300,000 in 2025 and supported a genetics and pathophysiology of epilepsy research project at Massachusetts General Hospital with $250,000. Their grantmaking also reaches reproductive equity work through intermediaries and service organizations. Examples include support for the Collaborative for Gender and Reproductive Equity at Rockefeller Philanthropy Advisors, Project Access Bridge at the Public Health Institute, and Project Free the Pill at Ibis Reproductive Health Inc. The portfolio also includes unrestricted support for policy, media, and advocacy organizations such as the Carnegie Endowment for International Peace, Council on Foreign Relations Inc, Advocates for Youth, and If When How. The overall picture is of a national funder combining research investment with reproductive health and equity advocacy.
Biomedical research is the clearest thread in the portfolio. In 2025, P-Squared Philanthropies Inc gave $300,000 to the Board of Trustees of the Leland Stanford Junio for the Parekh Metabolic Psychiatry Research Fund, and $250,000 to Massachusetts General Hospital for a research project on the complex genetics and pathophysiology of epilepsy. The foundation also made $35,000 grants to Tisch Multiple Sclerosis Research Center of New York in 2023 and 2025. Reproductive health and equity is another recurring area. The foundation gave $500,000 to Rockefeller Philanthropy Advisors Inc for the Collaborative for Gender and Reproductive Equity Program in 2023 and another $500,000 for the Collaborative for Gender and Reproductive Equity in 2025. It also funded Project Access Bridge - Advancing reproductive health equity in emergency departments at the Public Health Institute with $125,000, and Project Free the Pill at Ibis Reproductive Health Inc with $25,000. Advocacy and public education appear as smaller but visible themes, including support for Advocates for Youth’s AMAZE program and unrestricted work at If When How.
$3.8M
$107.8M
$17.1M
$5.9M
Most grants fall between $13K and $50K, with a median of $25K.
25th Percentile
$13K
Median
$25K
75th Percentile
$50K
About 0% of grants go to recipients in NY.
Top 2 recipient countries by grant volume for P-Squared Philanthropies.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 111 | $10.3M | 99.1% |
| 2 | Canada |
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Concentrated, high-dollar grants to a small number of recipients (8 grants totaling $4.55M) with multiple six- and seven-figure gifts; repeat and parallel support to the same institutions (NYU/NYU Langone) and use of intermediaries/donor-advised vehicles to channel programmatic initiatives.
Notable grantees: New York University / NYU Langone (Parekh Family Center for Neuroinflammation), Rockefeller Philanthropy Advisors (Collaborative for Gender and Reproductive Equity), Fidelity Investments Charitable Gift Fund (The Hypothesis Fund), Stanford University (Parekh Metabolic Psychiatry Research Fund), Massachusetts General Hospital (epilepsy genetics research)
Typical grant size centers on mid-sized awards: the reported distribution is $12,500 at the 25th percentile, $25,000 at the median, and $50,000 at the 75th percentile. The recent record also shows several very large strategic grants at $500,000 and $1,000,000, alongside many smaller event and project grants. The foundation appears to support some recipients across multiple years. New York University received center funding in both 2023 and 2025, Rockefeller Philanthropy Advisors Inc received Collaborative for Gender and Reproductive Equity support in both years, and several organizations such as If When How and Publicolor also reappear. P-Squared Philanthropies Inc is a regular funder, not a program-related investor, and the profile indicates it funds individuals.
P-Squared Philanthropies Inc gives nationally, with the highest concentration of grants going to recipients in Washington, DC. New York City appears frequently in the recent record through New York University, Rockefeller Philanthropy Advisors Inc, Council on Foreign Relations Inc, and others. Other repeated recipient locations include Boston, Oakland, and Los Angeles. All listed grants in the recent sample went to US recipients, and none went to recipients in Delaware.
The recent record centers on biomedical research and reproductive equity. Grants include neuroinflammation, metabolic psychiatry, epilepsy genetics and pathophysiology, the Collaborative for Gender and Reproductive Equity, reproductive health equity in emergency departments, and Project Free the Pill.
The reported grant-size distribution is $12,500 at the 25th percentile, $25,000 at the median, and $50,000 at the 75th percentile. The same record also includes larger strategic awards of $300,000, $500,000, and $1,000,000.
Yes. The record shows repeat giving to New York University in 2023 and 2025 for the Parekh Family Center for Neuroinflammation, and to Rockefeller Philanthropy Advisors Inc in both years for the Collaborative for Gender and Reproductive Equity. Other organizations also appear more than once.
Washington, DC is the top state-level concentration by grant count in the provided data. The geographic sample also shows frequent grants in New York City, Boston, Oakland, and Los Angeles, with all listed recipients located in the United States.
Yes. The foundation’s profile indicates it funds individuals. The recent-grants list itself focuses on organizations, academic institutions, and intermediaries rather than naming individual grantees.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| 1 |
| $50K |
0.9% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| NEW YORK UNIVERSITY | NEW YORK, NY | $1,000,000 | 2025 | THE PAREKH FAMILY CENTER FOR NEUROINFLAMMATION, OR SUCH OTHER NAME AS MAY BE MUTUALLY DETERMINED BY THE PARTIES WITHIN 60 DAYS OF EXECUTION OF THIS AGREEMENT (THE "CENTER") AND TO SUPPORT ITS ACTIVITIES (SUCH ESTABLISHMENT AND SUPPORT, THE "PROGRAM") |
| ROCKEFELLER PHILANTHROPY ADVISORS INC | NEW YORK, NY | $500,000 | 2025 | Collaborative for Gender and Reproductive Equity |
| FIDELITY INVESTMENTS CHARITABLE GIFT FUND | BOSTON, MA | $500,000 | 2025 | The Hypothesis Fund |
| THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO | STANFORD, CA | $300,000 | 2025 | Parekh Metabolic Psychiatry Research Fund |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $250,000 | 2025 | research project focused on understanding the complex genetics and pathophysiology of epilepsy |
| PUBLIC HEALTH INSTITUTE | OAKLAND, CA | $125,000 | 2025 | Project Access Bridge - Advancing reproductive health equity in emergency departments |
| CARNEGIE ENDOWMENT FOR INTERNATIONAL PEACE | WASHINGTON, DC | $100,000 | 2025 | General & Unrestricted |
| IF WHEN HOW | OAKLAND, CA | $100,000 | 2025 | General & Unrestricted |
| ADVOCATES FOR YOUTH | WASHINGTON, DC | $100,000 | 2025 | AMAZE program and unrestricted |
| COUNCIL ON FOREIGN RELATIONS INC | NEW YORK, NY | $100,000 | 2025 | General & Unrestricted |
| HEALTHY MOTHERS HEALTHY BABIES COALITION OF GEORGI | ATLANTA, GA | $50,000 | 2025 | General & Unrestricted |
| PUBLICOLOR INC | NEW YORK, NY | $50,000 | 2025 | Charitable Event |
| WOMEN MOVING MILLIONS INC | NEW YORK, NY | $50,000 | 2025 | General & Unrestricted |
| TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | PHILADELPHIA, PA | $50,000 | 2025 | Designation: Council for Discovery Science |
| PUBLICOLOR INC | NEW YORK, NY | $50,000 | 2025 | General & Unrestricted |
| 19TH NEWS | AUSTIN, TX | $50,000 | 2025 | General & Unrestricted |
| RESIST INC | JAMAICA PLAIN, MA | $40,000 | 2025 | For Birth Center Equity |
| SUNDANCE INSTITUTE | PARK CITY, UT | $35,000 | 2025 | General & Unrestricted |
| INDIASPORA | WASHINGTON, DC | $25,000 | 2025 | Founders Circle Fund |
| IBIS REPRODUCTIVE HEALTH INC | CAMBRIDGE, MA | $25,000 | 2025 | Project Free the Pill |
| EDUCATE GIRLS | AUSTIN, TX | $25,000 | 2025 | General & Unrestricted |
| TISCH MULTIPLE SCLEROSIS RESEARCH CENTER OF NEW YO | NEW YORK, NY | $25,000 | 2025 | Charitable Event |
| CENTER FOR INDEPENDENT DOCUMENTARY INC | NEWTON, MA | $25,000 | 2025 | Funds for documentary "Cutting through Rocks" |
| NEW YORK ABORTION ACCESS FUND | NEW YORK, NY | $25,000 | 2025 | General & Unrestricted |
| NEW YORK UNIVERSITY | NEW YORK, NY | $25,000 | 2025 | FACES (Finding a Cure for Epilepsy & seizures) |
| NEW YORK ABORTION ACCESS FUND | NEW YORK, NY | $25,000 | 2025 | New York Abortion Access Funds (NYAAF) |
| INTERNATIONAL CENTER OF PHOTOGRAPHY | NEW YORK, NY | $22,500 | 2025 | ICP toward the Collections Committee Dues; ICP Infinity Awards - Storyteller Sponsor |
| BREAKFAST REVOLUTION | BOSTON, MA | $20,000 | 2025 | General & Unrestricted |
| THE FILM COLLABORATIVE INC | LOS ANGELES, CA | $20,000 | 2025 | In Support of Documentary "Zurawski v Texas" |
| SAKHI FOR SOUTH ASIAN SURVIVORS INC | NEW YORK, NY | $10,000 | 2025 | General & Unrestricted |
| ORCHID FOUNDATION | NEW YORK, NY | $10,000 | 2025 | General & Unrestricted |
| NEW YORK WOMEN IN FILM & TELEVISION INC | JACKSON HTS, NY | $10,000 | 2025 | Old Chester Films, Creede documentary |
| VASSAR COLLEGE | POUGHKEEPSIE, NY | $10,000 | 2025 | Parekh Scholarship Fund 2024 |
| GIRLS WHO CODE INC | NEW YORK, NY | $10,000 | 2025 | In support of Moms First |
| COMMONSENSE CHILDBIRTH INC | WINTER GARDEN, FL | $10,000 | 2025 | Funds for Ancient Song Doula Services |
| EQUALITY NOW INC | BOSTON, MA | $10,000 | 2025 | Charitable Event |
| CHICKEN & EGG PICTURES INC | BROOKLYN, NY | $10,000 | 2025 | General & Unrestricted |
| SOZE FOUNDATION | BROOKLYN, NY | $5,000 | 2025 | General & Unrestricted |
| TEXAS TRIBUNE INC | AUSTIN, TX | $5,000 | 2025 | General & Unrestricted |
| ANTARA INTERNATIONAL INC | BROOKLYN, NY | $5,000 | 2025 | General & Unrestricted |
| BRIGID ALLIANCE INC | NEW YORK, NY | $5,000 | 2025 | General & Unrestricted |
| GO PHILANTHROPIC CHARITABLE FUND | PITTSFORD, NY | $4,500 | 2025 | Equal Community Foundation in support of implementing Antarang and the Online project raise training |
| MEETING HOUSE FAMILY CENTER INC | NEW YORK, NY | $2,500 | 2025 | General & Unrestricted |
| THE FIELD | NEW YORK, NY | $1,000 | 2025 | General & Unrestricted |
| NEW YORK UNIVERSITY | NEW YORK, NY | $1,000,000 | 2024 | The Parekh Family Center for Neuroinflammation, or such other name as may be mutually determined by the parties within 60 days of execution of this Agreement (the "Center") and to support its activities (such establishment and support, the "Program") |
| FIDELITY INVESTMENTS CHARITABLE GIFT FUND | BOSTON, MA | $500,000 | 2024 | The Hypothesis Fund |
| ROCKEFELLER PHILANTHROPY ADVISORS INC | NEW YORK, NY | $500,000 | 2024 | Collaborative for Gender and Reproductive Equity |
| THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO | STANFORD, CA | $300,000 | 2024 | General & Unrestricted |
| JOHNS HOPKINS UNIVERSITY | BALTIMORE, MD | $115,144 | 2024 | To expedite data analyses and time-to-publication of findings in the pursuit of identifying brain changes as a marker for neurologic Lyme disease, under the direction of Dr. Cherie Marvel (Principal Researcher) and ancillary staff (one research assistant) |
| CARNEGIE ENDOWMENT FOR INTERNATIONAL PEACE | WASHINGTON, DC | $100,000 | 2024 | General & Unrestricted |
THE PAREKH FAMILY CENTER FOR NEUROINFLAMMATION, OR SUCH OTHER NAME AS MAY BE MUTUALLY DETERMINED BY THE PARTIES WITHIN 60 DAYS OF EXECUTION OF THIS AGREEMENT (THE "CENTER") AND TO SUPPORT ITS ACTIVITIES (SUCH ESTABLISHMENT AND SUPPORT, THE "PROGRAM")
Collaborative for Gender and Reproductive Equity
Parekh Metabolic Psychiatry Research Fund
MASSACHUSETTS GENERAL HOSPITAL
research project focused on understanding the complex genetics and pathophysiology of epilepsy
Project Access Bridge - Advancing reproductive health equity in emergency departments
CARNEGIE ENDOWMENT FOR INTERNATIONAL PEACE
$100,000General & Unrestricted
COUNCIL ON FOREIGN RELATIONS INC
$100,000General & Unrestricted
Designation: Council for Discovery Science
RESIST INC
$40,000For Birth Center Equity
INDIASPORA
$25,000Founders Circle Fund
Funds for documentary "Cutting through Rocks"
NEW YORK ABORTION ACCESS FUND
$25,000General & Unrestricted
NEW YORK ABORTION ACCESS FUND
$25,000New York Abortion Access Funds (NYAAF)
ICP toward the Collections Committee Dues; ICP Infinity Awards - Storyteller Sponsor
BREAKFAST REVOLUTION
$20,000General & Unrestricted
ORCHID FOUNDATION
$10,000General & Unrestricted
NEW YORK WOMEN IN FILM & TELEVISION INC
$10,000Old Chester Films, Creede documentary
EQUALITY NOW INC
$10,000Charitable Event
SOZE FOUNDATION
$5,000General & Unrestricted
ANTARA INTERNATIONAL INC
$5,000General & Unrestricted
GO PHILANTHROPIC CHARITABLE FUND
$4,500Equal Community Foundation in support of implementing Antarang and the Online project raise training
MEETING HOUSE FAMILY CENTER INC
$2,500General & Unrestricted
The Parekh Family Center for Neuroinflammation, or such other name as may be mutually determined by the parties within 60 days of execution of this Agreement (the "Center") and to support its activities (such establishment and support, the "Program")
Collaborative for Gender and Reproductive Equity
To expedite data analyses and time-to-publication of findings in the pursuit of identifying brain changes as a marker for neurologic Lyme disease, under the direction of Dr. Cherie Marvel (Principal Researcher) and ancillary staff (one research assistant)
CARNEGIE ENDOWMENT FOR INTERNATIONAL PEACE
$100,000General & Unrestricted