The Myasthenia Gravis Foundation of America concentrates its funding on translational and clinical research that advances understanding, diagnosis, and treatment of myasthenia gravis (MG). Grants are targeted to university labs and clinical research centers pursuing antibody-specific mechanisms (MuSK and AChR), biomarker development, and patient-centered outcome measures, with some investment in programmatic networks and health-services research to accelerate clinical application.
Myasthenia Gravis Foundation of America Inc. centers its giving on translational and clinical research for myasthenia gravis, with recent awards aimed at antibody-specific mechanisms, biomarker validation, and patient-centered outcomes. One of the largest recent grants went to Yale University for work on defining new autoimmune mechanisms in seronegative MG, while another Yale award supported mechanistic study of the MuSK-specific autoantibody repertoire. The foundation’s portfolio also reaches beyond lab science into clinical research infrastructure and outcome measurement, including support for MG Net pilot studies at The George Washington University and a patient-reported outcome measure project at the University of Michigan. Its grants are sized for research projects rather than broad operating support, with awards often used to test hypotheses, validate diagnostic tools, or build multicenter research capacity. Recent grantees also include institutions working on AChR autoantibody effector functions, multiomics biomarker work, and studies tied to MG-related health disparities. The overall pattern is a focused research program built around improving understanding, diagnosis, and treatment of MG through academic and clinical research settings.
A major theme in the portfolio is mechanistic MG research. Yale University received $225,000 for measuring AChR autoantibody effector functions, and later $110,000 for novel mechanistic insights into the MuSK-specific autoantibody repertoire. Biomarker work is another clear emphasis: Uppsala University was awarded $110,000 to validate diagnostic and prognostic serum biomarkers for AChR antibody seropositive MG, while Duke University School of Medicine received $110,000 for multiomics-based immunological biomarker analysis. The foundation also funds patient-centered and clinical research. University of Michigan received $55,000 to validate a patient-reported outcome measure for ocular myasthenia gravis. In addition, Alira Health received three separate $10,000 awards in 2025 for studies on race and ethnicity in MG, race and income in MG care, and physical activity participation among patients with myasthenia.
Typical awards cluster around research-project scale funding: the median grant size is $110,000, with the 25th percentile at $50,000 and the 75th percentile at $159,999. The recent record shows repeat support for some recipients and programs, including The George Washington University’s MG Net pilot studies program in both 2023 and 2025. The foundation gives through named grant programs, including research grants, pilot project awards, post-doctoral fellowship support, and a clinician-scientist development award. Both unsolicited and program-based grant paths appear in the active programs listed.
$520K
$15.3M
$7.6M
$7.1M
Most grants fall between $50K and $160K, with a median of $110K.
25th Percentile
$50K
Median
$110K
75th Percentile
$160K
About 20% of grants go to recipients in CT.
Justin Stachtiaris
Top 2 recipient countries by grant volume for Myasthenia Gravis Foundation of America.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 19 | $2.3M | 95.0% |
| 2 | Sweden |
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Concentrated, research-focused giving primarily to academic medical centers and specialized research organizations; mix of multi-grant support to repeat institutional grantees (Yale, UPenn, GWU, Alira) and moderate-sized awards rather than many small community grants.
Notable grantees: Yale University, University of Pennsylvania, Duke University School of Medicine, The George Washington University (MG Net), American Brain Foundation
Grantmaking is national, and the recipient map is concentrated in U.S. research centers. Connecticut is the top state by grant count, led by Yale University in New Haven. Other frequently appearing U.S. locations include Philadelphia, New Haven, Ann Arbor, and Ashburn. The only non-U.S. recipient in the recent list is Uppsala University in Sweden, showing that the portfolio can extend internationally even though most grants stay in the United States.
It funds myasthenia gravis research focused on translational and clinical work, including mechanistic studies, biomarker validation, patient-reported outcomes, and clinical research capacity building. Recent awards include projects on MuSK and AChR autoantibodies, multiomics biomarker discovery, and ocular MG outcome measurement.
The typical award is around $110,000, with a 25th percentile of $50,000 and a 75th percentile of $159,999. Recent grants also include larger awards at $300,000 and smaller project awards at $10,000.
Both appear in the record. The George Washington University’s MG Net Pilot Studies program received $50,000 in 2023 and again in 2025, while several other awards were one-time project grants tied to specific studies.
No. The recent grants are mostly U.S.-based, but the portfolio includes Uppsala University in Sweden. The grant program descriptions also list some opportunities as open to both the United States and international applicants.
Yes. Several active programs are marked as accepting unsolicited applications, including MGFA Grant Funding / Apply for Grant Funding, MGFA Grant Funding (Research Grants), High-Impact Pilot Project Award, and MGFA Research Grant Funding. Other awards, such as the Jackie McSpadden Post-Doctoral Fellowship Award, are not marked as unsolicited.
2026
Source: IRS Form 990-PF, fiscal year 2026.
| 1 |
| $110K |
5.0% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| George Washington University - MGNet | Washington, DC | $250,000 | 2026 | "CAPTURE-MG study (Clinical Procedures To Support Research in Myasthenia Gravis) |
| American Brain Foundation | Minneapolis, MN | $159,999 | 2026 | Clinician Scientist Development Award in Myathenia Gravis |
| Boston Children's Hospital | Boston, MA | $110,000 | 2026 | Dissecting genetic determinants of dendritic cell dysfunction in myasthenia gravis |
| Yale University | New Haven, CT | $300,000 | 2025 | Defining new autoimmune mechanisms in seronegative MG |
| Duke University School of Medicine | Erwin Square, NC | $110,000 | 2025 | Deciphering Immunological Biomarkers in Myasthenia Gravis by Using Multiomics. |
| Uppsala University | Uppsala, Sw | $110,000 | 2025 | Validating diagnostic and prognostic serum biomarkers for AChR antibody seropositive MG |
| Yale University | New Haven, CT | $110,000 | 2025 | Novel mechanistic insights into the MuSK-specific autoantibody repertoire |
| The George Washington University | Ashbum, VA | $50,000 | 2025 | Dr Kaminski's MG Net Pilot Studies program |
| Alira Health | Framingham, MA | $10,000 | 2025 | Physical activity and factors associated with exercise participation among patients with myasthenia. |
| Alira Health | Framingham, MA | $10,000 | 2025 | Role of race and income in management of myasthenia gravis. |
| Alira Health | Framingham, MA | $10,000 | 2025 | Influence of race/ethnicity on clinical features of MG and inequalities in clinical care. |
| University of California Davis | Davis, CA | $110,000 | 2024 | AAV-mediated gene therapy for congenital myasthenia caused by recessive synaptotagmin 2 mutations. |
| Univeristy of California San Diego | La Jolla, CA | $110,000 | 2024 | Purification of the acetylcholine receptor toward atomic-scale mechanisms underlying MG |
| Mayo Clinic | Rochester, MN | $100,000 | 2024 | The 3' untranslated region variants and therapeutic targets in congenital myasthenic syndrome genes |
| The George Washington University | Ashburn, VA | $50,000 | 2024 | Dr Kaminski's MG Net Pilot Studies program |
| University of Pennsylvannia | Philadelphia, PA | $300,000 | 2023 | Preclinical models and biomarkers for predicting MuSK-CAART clinical outcomes |
| Yale University | New Haven, CT | $225,000 | 2023 | Measuring AChR autoantibody effector functions in myasthenia gravis patients. |
| American Brain Foundation | Minneapolis, MN | $159,999 | 2023 | Medical research |
| University of Michigan | Ann Arbor, MI | $55,000 | 2023 | Advancing patient-centered care and research for ocular myasthenia gravis: Validation of a novel patient reported outcome measure |
| The George Washington University | Ashbum, VA | $50,000 | 2023 | Dr Kaminski's MG Net Pilot Studies program |
George Washington University - MGNet
$250,000"CAPTURE-MG study (Clinical Procedures To Support Research in Myasthenia Gravis)
Clinician Scientist Development Award in Myathenia Gravis
Boston Children's Hospital
$110,000Dissecting genetic determinants of dendritic cell dysfunction in myasthenia gravis
Deciphering Immunological Biomarkers in Myasthenia Gravis by Using Multiomics.
Uppsala University
$110,000Validating diagnostic and prognostic serum biomarkers for AChR antibody seropositive MG
Novel mechanistic insights into the MuSK-specific autoantibody repertoire
Alira Health
$10,000Physical activity and factors associated with exercise participation among patients with myasthenia.
Alira Health
$10,000Role of race and income in management of myasthenia gravis.
Alira Health
$10,000Influence of race/ethnicity on clinical features of MG and inequalities in clinical care.
University of California Davis
$110,000AAV-mediated gene therapy for congenital myasthenia caused by recessive synaptotagmin 2 mutations.
Univeristy of California San Diego
$110,000Purification of the acetylcholine receptor toward atomic-scale mechanisms underlying MG
Mayo Clinic
$100,000The 3' untranslated region variants and therapeutic targets in congenital myasthenic syndrome genes
University of Pennsylvannia
$300,000Preclinical models and biomarkers for predicting MuSK-CAART clinical outcomes
Yale University
$225,000Measuring AChR autoantibody effector functions in myasthenia gravis patients.
University of Michigan
$55,000Advancing patient-centered care and research for ocular myasthenia gravis: Validation of a novel patient reported outcome measure