About Missouri Technology
Provide leadership and make strategic investments that help entrepreneurs create and grow technology-based Missouri businesses, focusing on 21st Century bioscience and technology industries that build on Missouri’s history in agriculture.
Focus Areas
Life sciences / biosciencesAgrotechnologyEarly-stage technology startupsVenture capital / equity investmentsEntrepreneurial ecosystem developmentWorkforce and job creation
Who They Fund
early-stage entrepreneurs and startups (including social ventures)small and mid-sized manufacturersbioscience / biotech firms and research-to-market entitiesregional innovation intermediaries (incubators, accelerators, tech hubs)regional / rural Missouri communities and economic regions (South, Southwest, Southeast, Central, Greater St. Louis, Kansas City)
About Missouri Technology
Missouri Technology Corporation’s recent grantmaking shows a public funder building Missouri’s technology economy through large strategic awards to infrastructure, startups, and regional intermediaries. In 2023, it granted $9.45 million to Api Innovation Center for active pharmaceutical ingredient manufacturing infrastructure in Missouri, and $5.4 million to Missouri State University for semiconductor manufacturing infrastructure. Those awards sit alongside support for entrepreneurial capacity work across St. Louis, Kansas City, Springfield, Columbia, and Cape Girardeau. The foundation backs both industry-specific capacity and the organizations that help founders and manufacturers operate within it. Biostl received $1.499 million in 2025 for support including BioGenerator’s non-investment activities, while Bionexus Kc received $936,050 in 2025 for the KC BioHub project. Missouri Technology Corporation also funds ecosystem builders such as Missouri Innovation Center, Missouri Enterprise, and Codefi Foundation, linking innovation infrastructure with business formation, training, and manufacturing support. Its portfolio reflects a mix of physical infrastructure, ecosystem development, and entrepreneurial support rather than a narrow single-program approach. The organization is a public charity, makes program-related investments, and works through grant programs that include physical infrastructure, investor education, advocacy, regional nodes, and statewide entrepreneurial capacity building.
What Missouri Technology Funds
Life sciences and biomanufacturing are a clear theme. Missouri Technology Corporation gave $9.45 million to Api Innovation Center for active pharmaceutical ingredient manufacturing infrastructure, and later $250,000 to Bionexus Kc for the KC inclusive biologics and biomanufacturing tech hub. Semiconductor-related infrastructure also appears in the portfolio. Missouri State University received $5.4 million in 2023 to develop semiconductor manufacturing infrastructure within Missouri. The foundation also funds entrepreneurship support tied to regional ecosystem growth. It awarded $2.091 million to Mayfield Entrepreneurial Center for startup incubator and accelerator space in Marble Hill, and $1.499 million to Biostl for support including BioGenerator’s non-investment activities. Agtech and manufacturing capacity show up as well. A 2024 grant of $480,000 to 39 North Agtech supported operations of the agtech innovation district in St. Louis, while Missouri Enterprise received funding for the operation of Missouri’s Manufacturing Extension Partnership.
Financial Snapshot
Annual Giving
$16.4M
Total Assets
$105.2M
Total Revenue
$11.2M
Total Expenses
$22.7M
Typical Grant Size
Most grants fall between $50K and $325K, with a median of $199K.
25th Percentile
$50K
Median
$199K
75th Percentile
$325K
Geographic Reach
Local1 state funded
Funding intensity
LowHigh
Headquarters
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