What are Manning Family Foundation’s main focus areas?

The foundation’s core areas are health and life sciences research and local Charlottesville-area grants. Within health research, its programs emphasize Type 1 diabetes, retinal diseases, translational research, and commercialization through university and research partnerships.

How does Manning Family Foundation fund local community needs?

Its local program supports Charlottesville-area nonprofits working on physical and mental health, services for at-risk youth, educational and developmental opportunities for children, and financial literacy. Recent local awards also include support for affordable housing and the Town of Gordonsville.

What is a typical grant size?

Typical awards are in the five-figure range: p25 is $10,000, the median is $21,350, and p75 is $70,000. Recent grants also include much larger transfers to donor-advised and charitable gift vehicles, along with million-dollar gifts to universities and research partners.

How do applicants apply for general grants?

The general grant program accepts online applications. First-time applicants, or organizations that have not been funded in two or more years, must submit a letter of inquiry before moving to a full application.

Manning Family Foundation

Name: Manning Family Foundation — grants, 990 financials & funding data
Creator: Kindora

ActivePhilanthropy & Voluntarism

CHARLOTTESVILLE, VAWebsite4349808100

About Manning Family Foundation

The Manning Family Foundation concentrates large, strategic gifts primarily to higher-education and medical research institutions—with a strong emphasis on the University of Virginia system—while also funding targeted health research (including COVID-19 and Type 1 diabetes) and local community needs in Charlottesville/Gordonsville. A significant portion of its outflow is channeled through donor-advised and charitable gift vehicles, indicating tax-efficient transfers and flexible grantmaking. The foundation favors a small number of high-dollar grants rather than many small awards and shows repeat support to several institutional grantees.

Focus Areas

University of Virginia medical and research enterprises (UVA Health, UVA Children’s Hospital)Major university research funding outside Virginia (University of Massachusetts)Biomedical research with emphasis on COVID-19 and translational programsType 1 diabetes research and translational funding (Breakthrough T1D)Local municipal and community support in Gordonsville/Charlottesville region

Who They Fund

research universities and academic medical centers (e.g., UVA, UMass)

About Manning Family Foundation

A defining feature of Manning Family Foundation’s grantmaking is its recurring support for the University of Virginia health and research ecosystem, including a $3.06 million grant to University of Virginia Health Foundation in 2025 and a $2.065 million grant to University of Virginia for COVID-19 research in 2024. The foundation’s largest recent gifts also include major transfers to charitable gift and donor-advised vehicles, showing a pattern of high-dollar, institution-centered giving rather than many small awards. Alongside university-based research, the foundation funds local needs in Charlottesville and Gordonsville and backs disease-focused work in diabetes and retinal research through partnerships and research institutions. Recent grants to Breakthrough T1D, University of Massachusetts, and Duke University show that its health and life sciences support is not limited to Virginia, even though most grants land there. The result is a grantmaker that combines concentrated institutional support with targeted research funding and local community giving.

What Manning Family Foundation Funds

In health and life sciences research, the foundation funds translational work through universities and research organizations. It gave $1.5 million to Breakthrough T1D in 2025, and it also supported the University of Massachusetts with $1 million grants in 2023, 2024, and 2025 through the Manning Innovation Program. The foundation’s diabetes-related partnerships extend to the University of Virginia as well, including the UVA LaunchPad for Diabetes Innovation. Local grantmaking is a separate track. In 2025, it awarded $300,000 to Affordable Housing Opportunity Fund, while earlier grants supported Ready Kids and The Women’s Initiative in Charlottesville. The foundation also backed the Town of Gordonsville with a $1 million grant in 2023, underscoring its place-based work in the region.

How Manning Family Foundation Gives

Typical grants cluster at a moderate-to-large scale, with p25 at $10,000, median at $21,350, and p75 at $70,000. The recent-grants record also shows repeated support to the same recipients across multiple years, including University of Massachusetts, Duke University, Affordable Housing Opportunity Fund, Ready Kids, and Big Brothers Big Sisters of Eastern Massachusetts. That pattern points to recurring institutional support rather than one-time-only awards. The foundation’s structure includes donor-advised and charitable gift vehicles, reflected in large transfers to Paul B Manning Charitable Gift Fund, Miscellaneous Contributions - Daf Account, and Fidelity Charitable. Applications for the general program are accepted online, and first-time applicants or organizations not funded in two or more years must submit an LOI before a full application.

Financial Snapshot

Annual Giving

$13.5M

Total Assets

$302.4M

Total Revenue

$8.4M

Total Expenses

$14.3M

Typical Grant Size

Most grants fall between $10K and $70K, with a median of $21K.

25th Percentile

$10K

Median

$21K

75th Percentile

$70K

Geographic Reach

Local10 states funded

Funding intensity

Low

High

Headquarters

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Recipient	Location	Amount	Year	Purpose
FIDELITY CHARITABLE	CINCINNATI, OH	$4,800,000	2025	GENERAL
UNIVERSITY OF VIRGINIA HEALTH FOUNDATION	CHARLOTTESVILLE, VA	$3,060,000	2025	GENERAL
BREAKTHROUGH T1D	NEW YORK, NY	$1,500,000	2025	GENERAL
UNIVERSITY OF MASSACHUSETTS	AMHERST, MA	$1,000,000	2025	GENERAL
DUKE UNIVERSITY	DURHAM, NC	$304,000	2025	GENERAL
AFFORDABLE HOUSING OPPORTUNITY FUND	CHARLOTTESVILLE, VA	$300,000	2025	GENERAL
CHARLOTTESVILLE BIOHUB	CHARLOTTESVILLE, VA	$255,000	2025	GENERAL
THE RED SOX FOUNDATION INC	BOSTON, MA	$250,000	2025	GENERAL
BIG BROTHERS BIG SISTERS OF EASTERN MASSACHUSETTS	BOSTON, MA	$200,000	2025	GENERAL
READY KIDS	CHARLOTTESVILLE, VA	$180,000	2025	GENERAL
CITY OF PROMISE	CHARLOTTESVILLE, VA	$154,470	2025	GENERAL
ALBEMARLE COUNTY POLICE FOUNDATION	CHARLOTTESVILLE, VA	$102,200	2025	GENERAL
BOYS AND GIRLS CLUBS OF CENTRAL VIRGINIA	CHARLOTTESVILLE, VA	$100,000	2025	GENERAL
HOSPICE OF THE PIEDMONT	CHARLOTTESVILLE, VA	$87,500	2025	GENERAL
THE WOMEN'S INITIATIVE	CHARLOTTESVILLE, VA	$75,000	2025	GENERAL
BLUE RIDGE AREA FOOD BANK	CHARLOTTESVILLE, VA	$75,000	2025	GENERAL
CHARLOTTESVILLE FREE CLINIC	CHARLOTTESVILLE, VA	$75,000	2025	GENERAL
TANDEM FRIENDS SCHOOL	CHARLOTTESVILLE, VA	$72,000	2025	GENERAL
FOUNDATION FOR FIGHTING BLINDNESS	COLUMBIA, MD	$61,335	2025	GENERAL
FOOTHILLS CHILD ADVOCACY CENTER	CHARLOTTESVILLE, VA	$58,000	2025	GENERAL
FRIENDS OF CHARLOTTESVILLE DOWNTOWN	CHARLOTTESVILLE, VA	$52,500	2025	GENERAL
EMERGENCY FOOD BANK	CHARLOTTESVILLE, VA	$50,000	2025	GENERAL
ON OUR OWN OF CHARLOTTESVILLE INC	CHARLOTTESVILLE, VA	$45,000	2025	GENERAL
PIEDMONT COURT APOINTED SPECIAL ADVOCATES INC	CHARLOTTESVILLE, VA	$40,000	2025	GENERAL
CHARLOTTESVILLE COMMUNITY BIKES	CHARLOTTESVILLE, VA	$40,000	2025	GENERAL
CENTER FOR NONPROFIT EXCELLENCE	CHARLOTTESVILLE, VA	$32,125	2025	GENERAL
CHILD HEALTH PARTNERSHIP	CHARLOTTESVILLE, VA	$30,000	2025	GENERAL
100 BLACK MEN OF CENTRAL VIRGINIA	CHARLOTTESVILLE, VA	$30,000	2025	GENERAL
BIG BROTHERS BIG SISTERS OF THE CENTRAL BLUE RIDGE	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
MONTANOVA STABLES FOUNDATION	KESWICK, VA	$25,000	2025	GENERAL
THE FRONT PORCH CVILLE	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
ELK HILL FARM INC	GOOCHLAND, VA	$25,000	2025	GENERAL
THOMAS JEFFERSON FOUNDATION	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
ALL BLESSINGS FLOW INC	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
THE PARAMOUNT THEATRE	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
CHRIS LONG FOUNDATION	CHARLOTTESVILLE, VA	$25,000	2025	GENERAL
VIRGINIA DISCOVERY MUSEUM	CHARLOTTESVILLE, VA	$20,000	2025	GENERAL
LITERACY VOLUNTEERS OF CHARLOTTESVILLEALBEMARLE	CHARLOTTESVILLE, VA	$20,000	2025	GENERAL
PIEDMONT FAMILY YMCA	CHARLOTTESVILLE, VA	$20,000	2025	GENERAL
AKA GEORGIA'S HEALING HOUSE	CHARLOTTESVILLE, VA	$20,000	2025	GENERAL
HER SPORTS	CHARLOTTESVILLE, VA	$15,000	2025	GENERAL
RECLAIMED HOPE INITIATIVE	CHARLOTTESVILLE, VA	$15,000	2025	GENERAL
LILLYLULU FOUNDATION INC	HINGHAM, MA	$15,000	2025	GENERAL
ASSOCIATION FOR RETARDED CITIZENS OF CHARLOTTESVIL	CHARLOTTESVILLE, VA	$15,000	2025	GENERAL
FRIENDS CANCER SUPPORT COMPANIONSTHE HOPE FUND	CHARLOTTESVILLE, VA	$10,000	2025	GENERAL
JEFFERSON SCHOOL AFRICAN AMERICAN HERITAGE CENTER	CHARLOTTESVILLE, VA	$10,000	2025	GENERAL
GIVING WORDS INC	CHARLOTTESVILLE, VA	$10,000	2025	GENERAL
ORANGE COUNTY FREE CLINIC	ORANGE, VA	$10,000	2025	GENERAL
THE FAMILY PANTRY OF CAPE COD	HARWICH, VA	$10,000	2025	GENERAL
RESCUE MISSION MINISTRIES	ROANOKE, VA	$10,000	2025	GENERAL

Recipient

Location

Amount

Year

Purpose

FIDELITY CHARITABLE

CINCINNATI, OH

$4,800,000

2025

GENERAL

UNIVERSITY OF VIRGINIA HEALTH FOUNDATION

CHARLOTTESVILLE, VA

$3,060,000

2025

GENERAL

BREAKTHROUGH T1D

NEW YORK, NY

$1,500,000

2025

GENERAL

UNIVERSITY OF MASSACHUSETTS

AMHERST, MA

$1,000,000

2025

GENERAL

DUKE UNIVERSITY

DURHAM, NC

$304,000

2025

GENERAL

AFFORDABLE HOUSING OPPORTUNITY FUND

CHARLOTTESVILLE, VA

$300,000

2025

GENERAL

CHARLOTTESVILLE BIOHUB

CHARLOTTESVILLE, VA

$255,000

2025

GENERAL

THE RED SOX FOUNDATION INC

BOSTON, MA

$250,000

2025

GENERAL

BIG BROTHERS BIG SISTERS OF EASTERN MASSACHUSETTS

BOSTON, MA

$200,000

2025

GENERAL

READY KIDS

CHARLOTTESVILLE, VA

$180,000

2025

GENERAL

CITY OF PROMISE

CHARLOTTESVILLE, VA

$154,470

2025

GENERAL

ALBEMARLE COUNTY POLICE FOUNDATION

CHARLOTTESVILLE, VA

$102,200

2025

GENERAL

BOYS AND GIRLS CLUBS OF CENTRAL VIRGINIA

CHARLOTTESVILLE, VA

$100,000

2025

GENERAL

HOSPICE OF THE PIEDMONT

CHARLOTTESVILLE, VA

$87,500

2025

GENERAL

THE WOMEN'S INITIATIVE

CHARLOTTESVILLE, VA

$75,000

2025

GENERAL

BLUE RIDGE AREA FOOD BANK

CHARLOTTESVILLE, VA

$75,000

2025

GENERAL

CHARLOTTESVILLE FREE CLINIC

CHARLOTTESVILLE, VA

$75,000

2025

GENERAL

TANDEM FRIENDS SCHOOL

CHARLOTTESVILLE, VA

$72,000

2025

GENERAL

FOUNDATION FOR FIGHTING BLINDNESS

COLUMBIA, MD

$61,335

2025

GENERAL

FOOTHILLS CHILD ADVOCACY CENTER

CHARLOTTESVILLE, VA

$58,000

2025

GENERAL

FRIENDS OF CHARLOTTESVILLE DOWNTOWN

CHARLOTTESVILLE, VA

$52,500

2025

GENERAL

EMERGENCY FOOD BANK

CHARLOTTESVILLE, VA

$50,000

2025

GENERAL

ON OUR OWN OF CHARLOTTESVILLE INC

CHARLOTTESVILLE, VA

$45,000

2025

GENERAL

PIEDMONT COURT APOINTED SPECIAL ADVOCATES INC

CHARLOTTESVILLE, VA

$40,000

2025

GENERAL

CHARLOTTESVILLE COMMUNITY BIKES

CHARLOTTESVILLE, VA

$40,000

2025

GENERAL

CENTER FOR NONPROFIT EXCELLENCE

CHARLOTTESVILLE, VA

$32,125

2025

GENERAL

CHILD HEALTH PARTNERSHIP

CHARLOTTESVILLE, VA

$30,000

2025

GENERAL

100 BLACK MEN OF CENTRAL VIRGINIA

CHARLOTTESVILLE, VA

$30,000

2025

GENERAL

BIG BROTHERS BIG SISTERS OF THE CENTRAL BLUE RIDGE

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

MONTANOVA STABLES FOUNDATION

KESWICK, VA

$25,000

2025

GENERAL

THE FRONT PORCH CVILLE

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

ELK HILL FARM INC

GOOCHLAND, VA

$25,000

2025

GENERAL

THOMAS JEFFERSON FOUNDATION

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

ALL BLESSINGS FLOW INC

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

THE PARAMOUNT THEATRE

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

CHRIS LONG FOUNDATION

CHARLOTTESVILLE, VA

$25,000

2025

GENERAL

VIRGINIA DISCOVERY MUSEUM

CHARLOTTESVILLE, VA

$20,000

2025

GENERAL

LITERACY VOLUNTEERS OF CHARLOTTESVILLEALBEMARLE

CHARLOTTESVILLE, VA

$20,000

2025

GENERAL

PIEDMONT FAMILY YMCA

CHARLOTTESVILLE, VA

$20,000

2025

GENERAL

AKA GEORGIA'S HEALING HOUSE

CHARLOTTESVILLE, VA

$20,000

2025

GENERAL

HER SPORTS

CHARLOTTESVILLE, VA

$15,000

2025

GENERAL

RECLAIMED HOPE INITIATIVE

CHARLOTTESVILLE, VA

$15,000

2025

GENERAL

LILLYLULU FOUNDATION INC

HINGHAM, MA

$15,000

2025

GENERAL

ASSOCIATION FOR RETARDED CITIZENS OF CHARLOTTESVIL

CHARLOTTESVILLE, VA

$15,000

2025

GENERAL

FRIENDS CANCER SUPPORT COMPANIONSTHE HOPE FUND

CHARLOTTESVILLE, VA

$10,000

2025

GENERAL

JEFFERSON SCHOOL AFRICAN AMERICAN HERITAGE CENTER

CHARLOTTESVILLE, VA

$10,000

2025

GENERAL

GIVING WORDS INC

CHARLOTTESVILLE, VA

$10,000

2025

GENERAL

ORANGE COUNTY FREE CLINIC

ORANGE, VA

$10,000

2025

GENERAL

THE FAMILY PANTRY OF CAPE COD

HARWICH, VA

$10,000

2025

GENERAL

RESCUE MISSION MINISTRIES

ROANOKE, VA

$10,000

2025

GENERAL

Manning Family Foundation

About Manning Family Foundation

Focus Areas

Who They Fund

About Manning Family Foundation

What Manning Family Foundation Funds

How Manning Family Foundation Gives

Financial Snapshot

Typical Grant Size

Geographic Reach

Deep Analysis

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Giving Approach

Funding Style

Topics

Where Manning Family Foundation Makes Grants

Frequently Asked Questions About Manning Family Foundation

What are Manning Family Foundation’s main focus areas?

How does Manning Family Foundation fund local community needs?

Does the foundation make repeat grants?

What is a typical grant size?

How do applicants apply for general grants?

Open Grant Opportunities

General Grant Program (Manning Family Foundation)

Health & Life Sciences Research Grants

Local Grants (Charlottesville-area)

Recent Grants

Manning Family Foundation

About Manning Family Foundation

Focus Areas

Who They Fund

About Manning Family Foundation

What Manning Family Foundation Funds

How Manning Family Foundation Gives

Financial Snapshot

Typical Grant Size

Geographic Reach

Unlock Deep Analysis

See Similar Funders

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Want a Personalized Pitch for Manning Family Foundation?

The Grant Brief

Giving Approach

Funding Style

Topics

Where Manning Family Foundation Makes Grants

Frequently Asked Questions About Manning Family Foundation

What are Manning Family Foundation’s main focus areas?

How does Manning Family Foundation fund local community needs?

Does the foundation make repeat grants?

What is a typical grant size?

How do applicants apply for general grants?

Open Grant Opportunities

General Grant Program (Manning Family Foundation)

Health & Life Sciences Research Grants

Local Grants (Charlottesville-area)

Recent Grants