The mission of the Isaiah Stone Foundation is to help families who care for someone who has epilepsy, support organizations seeking to cure the disease and inspire others to lead. We support people by giving them hope that a life without epilepsy is worth dreaming about, acting upon and pushing for each and every day.
A pair of large general-purpose grants to Cure Epilepsy in Chicago, including $70,000 in 2023 and $50,000 in 2024, shows how the Isaiah Stone Foundation Inc channels its giving toward epilepsy cure work. The foundation’s mission centers on helping families who care for someone with epilepsy, supporting organizations that seek a cure, and encouraging others to lead. Its active programs add a direct family-and-patient dimension to that mission: general grants for Oklahomans affected by pediatric epilepsy, safety-net support for Medicaid and lower-income families, and a designated fund for epilepsy-related programs at OU Children’s Hospital in Oklahoma City. Youth leadership also appears in the foundation’s scholarship work through Leadership Oklahoma’s youth program. The grant record suggests a small, focused funder with a regional footprint and a clear emphasis on epilepsy-related needs rather than broad health giving. Recent support reaches both research-oriented organizations and local family assistance, tying medical cure goals to immediate support for children and caregivers affected by pediatric epilepsy.
In pediatric epilepsy, the foundation gives direct support through its general grants and small grants program for Oklahomans affected by pediatric epilepsy, including Medicaid and lower-income families. That family-support side is paired with research-oriented funding, as shown by grants to Cure Epilepsy for general funds. The foundation also backs epilepsy-related programs at OU Children’s Hospital through its designated fund, linking philanthropic support to clinical and program activity in Oklahoma City. Beyond medical and family support, it funds youth leadership through a peer-voted scholarship in Leadership Oklahoma’s youth program. The scholarship is annual and partial, and it is tied to future leaders in Oklahoma. Across these areas, the foundation’s giving combines direct assistance, institutional support, and leadership development within the epilepsy community.
Typical grant size sits in a narrow band: the 25th percentile is $55,000, the median is $60,000, and the 75th percentile is $65,000. The recent record shows repeated support to the same grantee across multiple years, with Cure Epilepsy receiving grants in both 2023 and 2024. The foundation also operates multiple named programs rather than a single open grant line, including scholarship funding, designated program support, and general/small grants for families and partner organizations. Unsolicited applications are accepted for the general grant and small grants programs, and applicants are directed to a grant application form or to contact the foundation. It does not fund individuals directly, and it makes no program-related investments.
$50K
$226K
$49K
$10K
Most grants fall between $55K and $65K, with a median of $60K.
25th Percentile
$55K
Median
$60K
75th Percentile
$65K
About 0% of grants go to recipients in IL.
C RENZI STONE
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Grantmaking is regional, with the strongest concentration in Illinois by grant count. Recent grants in the record went to Chicago, IL, while the foundation’s program work is heavily centered on Oklahoma, including Oklahoma City and statewide youth leadership support. Recipient-country data show all grants in the United States. The foundation’s HQ is in Oklahoma City, but its giving pattern reaches beyond the headquarters state through research support in Illinois and local program support in Oklahoma.
Its giving centers on epilepsy-related needs: pediatric epilepsy support, epilepsy cure research, family caregiver assistance, medical education and training, and youth leadership scholarships. The active programs also include safety-net support for Medicaid and lower-income families and a designated fund for epilepsy-related programs at OU Children’s Hospital.
Yes, for some programs. The general grant program and the ISF Small Grants Program both accept unsolicited applications. The foundation directs applicants to a Grant Application Form or to contact the foundation for the general grant line.
The grant-size distribution is tight. The 25th percentile is $55,000, the median is $60,000, and the 75th percentile is $65,000. Recent grants also show larger individual awards, including $70,000 and $50,000 to Cure Epilepsy in consecutive years.
Yes. Cure Epilepsy received grants in both 2023 and 2024, indicating repeat support rather than a one-time award pattern in at least one case.
The foundation focuses on children with epilepsy, family caregivers, low-income and Medicaid families, epilepsy researchers and clinical trainees, and youth and scholarship recipients affected by epilepsy. Its programs and grant descriptions consistently point to those groups.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Current and upcoming funding from Isaiah Stone Foundation that your nonprofit may be able to apply for.
Who can apply: Qualifying applicants affected by pediatric epilepsy in Oklahoma; specific eligibility determined by application review.
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Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| CURE EPILEPSY | CHICAGO, IL | $50,000 | 2024 | GENERAL FUNDS |
| CURE EPILEPSY | CHICAGO, IL | $70,000 | 2023 | GENERAL FUNDS |
