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    3. Howard Hughes Medical Institute
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    Howard Hughes Medical Institute

    ActiveMedical Research
    CHEVY CHASE, MDWebsite3012158500

    About Howard Hughes Medical Institute

    The Howard Hughes Medical Institute (HHMI) advances the discovery and sharing of scientific knowledge to benefit us all; HHMI is a biomedical research organization and philanthropy that supports scientific research, science education, and public engagement.

    Focus Areas

    Biomedical researchBasic biological sciencesScience educationPublic engagementResearch training and career-stage supportInternational research programs

    Who They Fund

    K-12 studentsK-12 science teachershigher-education faculty researchers (H. Gray Scholars)underrepresented students and faculty in STEM fieldsmedical researchers

    About Howard Hughes Medical Institute

    Howard Hughes Medical Institute’s recent grants show a strong pattern of large, multi-institution awards in science education and research training, alongside support for biomedical and basic biological research. One of the clearest examples is the $3,198,600 grant to the University of Alaska Anchorage for Inclusive Excellence 3 Learning Community, which reflects HHMI’s emphasis on learning communities and inclusive excellence in STEM. The institute also backs major national science education work, including a $3,000,000 grant to the University of Pittsburgh for Science Education Alliance and a $3,000,000 grant to Loudoun County Public Schools for K-12 science education activities. Its portfolio extends beyond classrooms into faculty development and medical research. HHMI awarded $2,560,000 to Vanderbilt University for H. Gray Scholars - Faculty and $2,900,000 to the Allen Institute for Medical Research. These grants fit the organization’s broader mission of advancing scientific knowledge through research, education, and public engagement. The recent record also includes repeated support for structured programs such as Driving Change and H. Gray Scholars, indicating a preference for named initiatives that build capacity across institutions rather than one-off project sponsorships.

    What Howard Hughes Medical Institute Funds

    HHMI funds a mix of K-12 science education, faculty development, and research-focused programming. In K-12 science education, it gave $3,000,000 to Loudoun County Public Schools for support of K-12 science education activities and $1,500,000 to Montgomery County Public Schools Educational Foundation Inc for the same type of work. For higher-education faculty support, the foundation backed Vanderbilt University with $2,560,000 for H. Gray Scholars - Faculty and awarded $1,658,760 to Stanford University for H. Gray Scholars - Grant. It also supported similar faculty awards at Stanford Univ, Yale University, University of California-San Francisco, University of Colorado Boulder, University of California - San Diego, and Boston University. In research and advanced training, HHMI gave $2,900,000 to the Allen Institute for Medical Research, $2,026,905 to UNC Chapel Hill for Medical Research, and $1,950,000 to Marine Biological Lab for Advanced Courses.

    How Howard Hughes Medical Institute Gives

    Financial Snapshot

    Annual Giving

    $8.8M

    Total Assets

    $29.5B

    Total Revenue

    $2B

    Total Expenses

    $1.2B

    Typical Grant Size

    Most grants fall between $50K and $783K, with a median of $473K.

    25th Percentile

    $50K

    Median

    $473K

    75th Percentile

    $783K

    Geographic Reach

    National47 states funded

    About 5% of grants go to recipients in CA.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

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    Privacy PolicyTerms of ServiceSystem Status
    EIN (Tax ID): 59-0735717Latest Form 990: 2026Total assets: $29.5B4 filings on recordFind their full 990 filing →
    See If You're a Fit — FreeFree account · instant fit score · similar funders

    Funding Style

    capacity building (teacher and faculty development)professional development and learning communitiesresearch and pilot grant support (scholar/grant awards)programmatic support for curriculum/advanced courses

    Topics

    K-12 science education and curriculum developmentscience teacher professional developmenthigher-education faculty development (H. Gray Scholars)inclusive excellence / diversity, equity, and inclusion in STEMmedical research supportcreation and support of cross-institutional learning communities

    Typical grant size is substantial: the 25th percentile is $50,000, the median is $472,833, and the 75th percentile is $782,716. The recent list shows both smaller institutional awards and many multi-million-dollar grants, which suggests HHMI uses a layered grantmaking model across programmatic and research support. The same program names recur across years and institutions, especially Driving Change and H. Gray Scholars, pointing to recurring, structured support rather than isolated gifts. HHMI is a regular funder, not a DAF, and it does not fund individuals. It also does not make program-related investments.

    Where Howard Hughes Medical Institute Makes Grants

    HHMI’s giving is national, and every grant in the provided recent sample went to U.S. recipients. Grants are spread across many states, with New York appearing most often by grant count. Recent recipient locations include Ashburn, VA; Seattle, WA; Albany, NY; Los Angeles, CA; Charlottesville, VA; and Columbia and New Haven-area campuses through university awards in the Northeast. Maryland accounts for 5% of grants, but the foundation’s activity is broader than its Chevy Chase headquarters.

    Frequently Asked Questions About Howard Hughes Medical Institute

    What kinds of work does Howard Hughes Medical Institute support?

    HHMI supports biomedical research, basic biological sciences, science education, public engagement, research training, and international research programs. Recent awards also show specific support for K-12 science education, faculty development, inclusive excellence learning communities, and medical research.

    Does HHMI make grants to individuals?

    No. The foundation is listed as not funding individuals, and the recent grant record is made up of institutional awards to universities, public school systems, and research organizations.

    What is a typical HHMI grant size?

    The grant-size distribution is sizable: the 25th percentile is $50,000, the median is $472,833, and the 75th percentile is $782,716. The recent grants list also includes several awards in the $1 million to $3 million range.

    Is HHMI’s grantmaking concentrated in one place?

    No. The foundation’s scope is national, and the recent sample includes recipients in many states. New York is the top state by grant count, while Maryland represents 5% of grants. The recent grants also reach institutions in California, Virginia, Washington, and Massachusetts.

    Does HHMI appear to support recurring programs?

    Yes. Program names recur across multiple grants and years, especially Driving Change and H. Gray Scholars. The sample also includes repeated support for science education activities and advanced courses, which suggests a structured, ongoing grantmaking approach.

    ERIN K O'SHEA PHD

    PRESIDENT

    Accepts unsolicited proposals
    Latest 990 Filing

    2026

    Source: IRS Form 990-PF, fiscal year 2026.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    UNIVERSITY OF CALIFORNIA SAN FRANCISCOSAN FRANCISCO, CA$3,062,9532026MEDICAL RESEARCH
    HARVARD UNIVERSITYCAMBRIDGE, MA$2,113,2152026MEDICAL RESEARCH
    YALE UNIVERSITYNEW HAVEN, CT$1,286,3662026MEDICAL RESEARCH
    LOUDOUN COUNTY PUBLIC SCHOOLSASHBURN, VA$1,000,0002026SUPPORT OF K-12 SCIENCE EDUCATION ACTIVITIES
    STANFORD UNIVERSITYREDWOOD CITY, CA$502,7422026MEDICAL RESEARCH
    NORTH CAROLINA CENTRAL UNIVERSITYDURHAM, NC$370,4652026SCIENCE EDUCATION ALLIANCE
    HELEN HAY WHITNEY FOUNDATIONNEW YORK, NY$73,5002026MEDICAL RESEARCH
    UNIVERSITY OF OKLAHOMANORMAN, OK$39,6002026BIOINTERACTIVE
    UNIVERSITY OF RHODE ISLAND FOUNDATIONKINGSTON, RI$25,0002026DRIVING CHANGE
    UNIVERSITY OF CALIFORNIA MERCEDMERCED, CA$25,0002026DRIVING CHANGE
    NORTH CAROLINA A & T STATE UNIVERSITYGREENSBORO, NC$25,0002026DRIVING CHANGE
    NEW MEXICO STATE UNIVERSITYLAS CRUCES, NM$25,0002026DRIVING CHANGE
    THE AMERICAN SOCIETY FOR CELL BIOLOGYROCKVILLE, MD$25,0002026SUPPORT FOR THE SAN FRANCISCO DECLARATION ON RESEARCH ASSESSMENT (DORA)
    WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCHCAMBRIDGE, MA$20,0002026MEDICAL RESEARCH
    ELIZABETH CITY STATE UNIVERSITYELIZABETH CITY, NC$20,0002026SCIENCE EDUCATION ALLIANCE
    FAYETTEVILLE STATE UNIVERSITYFAYETTEVILLE, NC$20,0002026SCIENCE EDUCATION ALLIANCE
    THE CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATIONPHILADELPHIA, PA$20,0002026MEDICAL RESEARCH
    BENNETT COLLEGEGREENSBORO, NC$20,0002026SUPPORT BENNETT COLLEGE IN OFFERING THE SEA-PHAGES PROJECT
    NORTH CAROLINA A & T STATE UNIVERSITYGREENSBORO, NC$20,0002026SCIENCE EDUCATION ALLIANCE
    SAINT AUGUSTINE'S UNIVERSITYRALEIGH, NC$20,0002026SCIENCE EDUCATION ALLIANCE
    CINCINNATI CHILDREN'S HOSPITAL MED CTRCINCINNATI, OH$10,0002026MEDICAL RESEARCH
    ALLEN INSTITUTESEATTLE, WA$10,0002026MEDICAL RESEARCH
    JOHNS HOPKINS UNIVERSITYBALTIMORE, MD$10,0002026MEDICAL RESEARCH
    UNIVERSITY OF OKLAHOMANORMAN, OK$10,0002026MEDICAL RESEARCH
    UNIVERSITY OF KENTUCKYLEXINGTON, KY$10,0002026MEDICAL RESEARCH
    NATURE FORWARDCHEVY CHASE, MD$10,0002026SUPPORT ENVIRONMENTAL LITERACY EDUCATIONAL OUTREACH
    LA JOLLA INSTITUTE FOR IMMUNOLOGYLA JOLLA, CA$10,0002026MEDICAL RESEARCH
    REGENTS OF THE UNIVERSITY OF MICHIGANANN ARBOR, MI$10,0002026MEDICAL RESEARCH
    MASSACHUSETTS INSTITUTE OF TECHNOLOGYCAMBRIDGE, MA$10,0002026MEDICAL RESEARCH
    BOSTON CHILDREN'S HOSPITALBOSTON, MA$10,0002026MEDICAL RESEARCH
    THE BROAD INSTITUTE INCCAMBRIDGE, MA$10,0002026MEDICAL RESEARCH
    University of Pittsburgh—$3,000,0002025Science Education Alliance
    Vanderbilt University—$2,560,0002025H. Gray Scholars - Faculty
    Rice University—$2,500,0002025Driving Change
    University of Massachusetts Amherst—$2,500,0002025Driving Change
    Illinois State University—$2,500,0002025Driving Change
    Rutgers University-Camden—$2,500,0002025Driving Change
    University of California at Los Angeles—$2,500,0002025Driving Change
    University of Vermont—$2,500,0002025Driving Change
    Stanford University—$1,658,7602025H. Gray Scholars - Grant
    Washington University—$1,280,0002025H. Gray Scholars - Faculty
    Boston University—$1,280,0002025H. Gray Scholars - Faculty
    University Of California - Davis—$1,280,0002025H. Gray Scholars - Faculty
    University of Colorado Boulder—$1,280,0002025H. Gray Scholars - Faculty
    University of California - San Francisco—$1,280,0002025H. Gray Scholars - Faculty
    Icahn School Of Medicine At Mount Sinai—$1,280,0002025H. Gray Scholars - Faculty
    University of California - San Diego—$1,280,0002025H. Gray Scholars - Faculty
    University of Washington School of Medicine—$1,280,0002025H. Gray Scholars - Faculty
    Case Western Reserve Univ—$1,280,0002025H. Gray Scholars - Faculty
    University Of California - Berkeley—$1,280,0002025H. Gray Scholars - Faculty

    UNIVERSITY OF CALIFORNIA SAN FRANCISCO

    $3,062,953
    SAN FRANCISCO, CA2026

    MEDICAL RESEARCH

    HARVARD UNIVERSITY

    $2,113,215
    CAMBRIDGE, MA2026

    MEDICAL RESEARCH

    YALE UNIVERSITY

    $1,286,366
    NEW HAVEN, CT2026

    MEDICAL RESEARCH

    LOUDOUN COUNTY PUBLIC SCHOOLS

    $1,000,000
    ASHBURN, VA2026

    SUPPORT OF K-12 SCIENCE EDUCATION ACTIVITIES

    STANFORD UNIVERSITY

    $502,742
    REDWOOD CITY, CA2026

    MEDICAL RESEARCH

    NORTH CAROLINA CENTRAL UNIVERSITY

    $370,465
    DURHAM, NC2026

    SCIENCE EDUCATION ALLIANCE

    HELEN HAY WHITNEY FOUNDATION

    $73,500
    NEW YORK, NY2026

    MEDICAL RESEARCH

    UNIVERSITY OF OKLAHOMA

    $39,600
    NORMAN, OK2026

    BIOINTERACTIVE

    UNIVERSITY OF RHODE ISLAND FOUNDATION

    $25,000
    KINGSTON, RI2026

    DRIVING CHANGE

    UNIVERSITY OF CALIFORNIA MERCED

    $25,000
    MERCED, CA2026

    DRIVING CHANGE

    NORTH CAROLINA A & T STATE UNIVERSITY

    $25,000
    GREENSBORO, NC2026

    DRIVING CHANGE

    NEW MEXICO STATE UNIVERSITY

    $25,000
    LAS CRUCES, NM2026

    DRIVING CHANGE

    THE AMERICAN SOCIETY FOR CELL BIOLOGY

    $25,000
    ROCKVILLE, MD2026

    SUPPORT FOR THE SAN FRANCISCO DECLARATION ON RESEARCH ASSESSMENT (DORA)

    WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH

    $20,000
    CAMBRIDGE, MA2026

    MEDICAL RESEARCH

    ELIZABETH CITY STATE UNIVERSITY

    $20,000
    ELIZABETH CITY, NC2026

    SCIENCE EDUCATION ALLIANCE

    FAYETTEVILLE STATE UNIVERSITY

    $20,000
    FAYETTEVILLE, NC2026

    SCIENCE EDUCATION ALLIANCE

    THE CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION

    $20,000
    PHILADELPHIA, PA2026

    MEDICAL RESEARCH

    BENNETT COLLEGE

    $20,000
    GREENSBORO, NC2026

    SUPPORT BENNETT COLLEGE IN OFFERING THE SEA-PHAGES PROJECT

    NORTH CAROLINA A & T STATE UNIVERSITY

    $20,000
    GREENSBORO, NC2026

    SCIENCE EDUCATION ALLIANCE

    SAINT AUGUSTINE'S UNIVERSITY

    $20,000
    RALEIGH, NC2026

    SCIENCE EDUCATION ALLIANCE

    CINCINNATI CHILDREN'S HOSPITAL MED CTR

    $10,000
    CINCINNATI, OH2026

    MEDICAL RESEARCH

    ALLEN INSTITUTE

    $10,000
    SEATTLE, WA2026

    MEDICAL RESEARCH

    JOHNS HOPKINS UNIVERSITY

    $10,000
    BALTIMORE, MD2026

    MEDICAL RESEARCH

    UNIVERSITY OF OKLAHOMA

    $10,000
    NORMAN, OK2026

    MEDICAL RESEARCH

    UNIVERSITY OF KENTUCKY

    $10,000
    LEXINGTON, KY2026

    MEDICAL RESEARCH

    NATURE FORWARD

    $10,000
    CHEVY CHASE, MD2026

    SUPPORT ENVIRONMENTAL LITERACY EDUCATIONAL OUTREACH

    LA JOLLA INSTITUTE FOR IMMUNOLOGY

    $10,000
    LA JOLLA, CA2026

    MEDICAL RESEARCH

    REGENTS OF THE UNIVERSITY OF MICHIGAN

    $10,000
    ANN ARBOR, MI2026

    MEDICAL RESEARCH

    MASSACHUSETTS INSTITUTE OF TECHNOLOGY

    $10,000
    CAMBRIDGE, MA2026

    MEDICAL RESEARCH

    BOSTON CHILDREN'S HOSPITAL

    $10,000
    BOSTON, MA2026

    MEDICAL RESEARCH

    THE BROAD INSTITUTE INC

    $10,000
    CAMBRIDGE, MA2026

    MEDICAL RESEARCH

    University of Pittsburgh

    $3,000,000
    2025

    Science Education Alliance

    Vanderbilt University

    $2,560,000
    2025

    H. Gray Scholars - Faculty

    Rice University

    $2,500,000
    2025

    Driving Change

    University of Massachusetts Amherst

    $2,500,000
    2025

    Driving Change

    Illinois State University

    $2,500,000
    2025

    Driving Change

    Rutgers University-Camden

    $2,500,000
    2025

    Driving Change

    University of California at Los Angeles

    $2,500,000
    2025

    Driving Change

    University of Vermont

    $2,500,000
    2025

    Driving Change

    Stanford University

    $1,658,760
    2025

    H. Gray Scholars - Grant

    Washington University

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    Boston University

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University Of California - Davis

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University of Colorado Boulder

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University of California - San Francisco

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    Icahn School Of Medicine At Mount Sinai

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University of California - San Diego

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University of Washington School of Medicine

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    Case Western Reserve Univ

    $1,280,000
    2025

    H. Gray Scholars - Faculty

    University Of California - Berkeley

    $1,280,000
    2025

    H. Gray Scholars - Faculty