
The Henry L Guenther Foundation is a health-focused funder that makes sizable capital and equipment grants to hospitals, medical centers, and biomedical research institutes—primarily in Southern California. Their support targets upgrades that directly improve clinical care (ICU, cath labs, imaging, ECMO), specialized programs for pediatrics and cardiovascular care, and research-grade instrumentation that advances biomedical discovery and training.
A $500,000 grant to Rady Children’s Hospital-San Diego for the Little Heroes League Care Coordination Program shows the Henry L Guenther Foundation’s pattern clearly: it backs California health and human-service organizations with large, practical awards that improve care delivery, equipment, and patient support. The foundation gives at a meaningful scale, with a median grant size of $22,500 and several awards far above that level for capital projects and clinical infrastructure. Its recent grants include hospital expansions, specialized care programs, and research tools, but the through line is consistent: funding that helps organizations treat patients, build capacity, or reduce suffering. Among the larger recent awards, the foundation gave $500,000 to Memorial Medical Center Foundation FBO Miller for ECMO expansion serving pediatric heart and lung failure patients and complex heart surgeries. It also supported Cedars-Sinai Medical Center with $450,000 for a Thermo Fisher Bigfoot Spectral Flow Cytometer and Cell Sorter, linking its giving to biomedical research capacity as well as direct care. These grants sit alongside support for cath labs, imaging, surgical technology, and care-coordination programs across Southern California.
The foundation’s health focus appears in multiple grant types. In pediatric care, it awarded $500,000 to Rady Children’s Hospital-San Diego for the Little Heroes League Care Coordination Program, and another $500,000 to Memorial Medical Center Foundation FBO Miller for ECMO equipment serving children with heart and lung failure. Cardiovascular infrastructure is another recurring area. It gave $450,000 to Providence Little Company of Mary Foundation for equipment and technology upgrades for the Del Vicario Cardiovascular Center of Excellence, and $300,000 to Glendale Adventist Medical Center Foundation to renovate four catheterization labs. Research and diagnostics also receive support. Cedars-Sinai Medical Center received $450,000 for a Thermo Fisher Bigfoot Spectral Flow Cytometer and Cell Sorter, while Saint John’s Health Center Foundation received $200,000 for a NextSeq2000 sequencer. The foundation also funds workforce and facility improvements, including $275,000 to Magan Hall Loma Linda University for a nursing mannequin laboratory.
$4.2M
$115.9M
$7.5M
$6.5M
Most grants fall between $15K and $54K, with a median of $23K.
25th Percentile
$15K
Median
$23K
75th Percentile
$54K
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Concentrated, large one-time capital grants (typically $275k–$500k) directed at facility/building projects, specialized equipment, and program start-up needs. Giving is regionally focused in Southern California, distributed across many hospital and research recipients rather than repeated multi-year support to the same organizations.
Notable grantees: Rady Children's Hospital — San Diego, Cedars-Sinai Medical Center, Providence Little Company of Mary Foundation, Salk Institute for Biological Studies, USC Verdugo Hills Hospital Foundation
Typical awards cluster below the largest grants but remain substantial: p25 is $15,000, the median is $22,500, and p75 is $54,000. The recent record also includes a long tail of capital and equipment grants at $100,000 to $500,000, which suggests a mix of routine program support and larger one-time project funding. The foundation is a regular funder rather than a DAF, and it makes grants on a 12-month basis. Recipient repetition appears in the data, including Long Beach Medical Center and several other California health institutions receiving more than one award across recent years. It also accepts unsolicited applications through its general grant programs.
Giving is concentrated entirely in California: 100% of grants in the recipient-country data went to US organizations, and every recent grantee listed is in California. Southern California cities appear repeatedly, including San Diego, Los Angeles, Long Beach, Torrance, Glendale, Orange, La Jolla, Santa Monica, and Newport Beach. The pattern points to a local California footprint with particular emphasis on Los Angeles, Orange County, and the San Diego area. No non-US recipient countries appear in the grant list.
It funds qualified tax-exempt charitable organizations operating in California, with a strong emphasis on hospitals, medical centers, biomedical research institutes, and other groups working to improve social conditions, promote human welfare, and alleviate pain and suffering. Recent grants also include human services, nursing education, and community benefit projects.
The foundation’s grant sizes cluster around a median of $22,500, with the 25th percentile at $15,000 and the 75th percentile at $54,000. Recent awards also include larger capital grants in the $100,000 to $500,000 range.
The foundation gives locally in California. In the recent grants list, 100% of recipients are in California, with frequent awards to organizations in Los Angeles, Long Beach, Torrance, San Diego, Glendale, and Orange.
Yes. Its general grant programs state that unsolicited applications are accepted, and they are open to qualified tax-exempt charitable organizations operating within California.
The grants are for a 12-month period, and the recent record shows repeat support to some organizations across different years, including Long Beach Medical Center and other California health institutions.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| Rady Children's Hospital- San Diego | San Diego, CA | $500,000 | 2025 | support the Little Heroes League Care Coordination Program. |
| Cedars-Sinai Medical Center | Los Angeles, CA | $450,000 | 2025 | support Thermo Fisher Bigfoot Spectral Flow Cytometer and Cell Sorter which represents the greatest innovation in the field of research and provides exponential levels of resolution to identify rare single cells contributing to diseases. |
| Providence Little Company of Mary Foundation | Torrance, CA | $450,000 | 2025 | support equipment and technology upgrades for the Del Vicario Cardiovascular Center of Excellence to improve the way in which we diagnose and treat cardiovascular care in community. |
| Glendale Adventist Medical Center Foundation | Glendale, CA | $300,000 | 2025 | renovate four catheterization labs. |
| Salk Institute for Biological Studies | La Jolla, CA | $288,000 | 2025 | purchase an Axioscan 7 system. |
| Long Beach Medical Center | Long Beach, CA | $250,000 | 2025 | purchase a new laser system necessary for minimally invasive cardiovascular procedures including coronary and peripheral atherectomies, thoracic aortic aneurysm repair, endovascular abdominal aortic repair, and more. |
| Saint John's Health Center Foundation | Santa Monica, CA | $200,000 | 2025 | purchase the next-generation sequencer NextSeq2000. |
| Braille Institute of America Inc | Los Angeles, CA | $200,000 | 2025 | support library services. |
| Jenesse Center Inc | Los Angeles, CA | $150,000 | 2025 | renovate a recently purchased facility in an unserved/underserved section of South Los Angeles to provide comprehensive services to transition violence victims from crisis to stability and on to self-sufficiency. |
| Mater Dei High School | Santa Ana, CA | $100,000 | 2025 | support construction of a performing arts center to support the Mater Dei community as well as the broader Santa Ana and Orange County communities. |
| Richstone Center Inc | Hawthorne, CA | $85,000 | 2025 | To identify and implement a new County and State compliant electronic health record (EHR) system. |
| Alzheimer's Greater Los Angeles | Los Angeles, CA | $75,000 | 2025 | support the clinical team for dementia care to vulnerable patients. |
| American Red Cross | Santa Ana, CA | $62,000 | 2025 | purchase a new Ram ProMaster 3500. |
| Madera County Food Bank | Madera, CA | $50,000 | 2025 | provide current patrons with additional food support and expand the current number of patrons. |
| Second Harvest Food Bank of Orange County | Irvine, CA | $50,000 | 2025 | support operation of Harvest Solutions Farm. |
| Union Station Homeless Services | Pasadena, CA | $50,000 | 2025 | renovate the permanent supportive housing building Euclid Villa. |
| Los Angeles House of Ruth | Los Angeles, CA | $50,000 | 2025 | help cover the final costs of the building of a Community Building. |
| House Institute Foundation | Los Angeles, CA | $50,000 | 2025 | sustain and grow research, education, and hearing health care initiatives. |
| The Dragon Kim Foundation | Irvine, CA | $50,000 | 2025 | expand opportunities for youth through equitable and inclusive entrepreneurship leadership training opportunities for high school students across Southern CA. |
| Conejo Free Clinic | Thousand Oaks, CA | $50,000 | 2025 | sustain and expand the Conejo Free Clinic's Senior Dentistry Program by supporting direct treatment, treatment supplies and advanced specialty dentures; completed care for over 400 low income seniors with no options for care. |
| Fallbrook Senior Citizens Service Club | Fallbrook, CA | $45,000 | 2025 | buy food and pay staff for the Nutrition Program that aims to reduce both food insecurity and social isolation among older adults by offering nutritious meals, entertainment, and activities in a communal setting. |
| St Anne's Family Services | Los Angeles, CA | $40,000 | 2025 | support young women and girls impacted by foster care and juvenile justice in our Short-Term Residential Therapeutic Program (STRTP), ages 13-18, and Transitional Housing Program, ages 18-25, who are pregnant and parenting. |
| Project Understanding of San Buenaventura | Ventura, CA | $35,000 | 2025 | purchase a used truck to transport food donations. |
| St Vincent de Paul Village Inc | San Diego, CA | $32,000 | 2025 | purchase a panoramic radiograph and an oral surgery handpiece for dental clinic to improve access to - and quality of - oral health care for neighbors experiencing or at-risk of homelessness. |
| United Through Reading | San Diego, CA | $30,000 | 2025 | support Southern CA programming through book distribution events, ensure deploying units have equipment and supplies needed for story stations, operate the Mobile Story Station West, and train United Through Reading volunteers. |
| Child & Family Center | Santa Clarita, CA | $30,000 | 2025 | support C&FC's Domestic Violence program - the only DV program and shelter in L.A. County's 3rd largest city. |
| Healing California | Alhambra, CA | $30,000 | 2025 | purchase new mobile dental units. |
| Boys Club of Fallbrook | Fallbrook, CA | $30,000 | 2025 | support new teen center project. |
| Long Beach Rescue Mission | Long Beach, CA | $25,000 | 2025 | support the physical, emotional, mental and spiritual needs of people experiencing homelessness in Long Beach, including hot meals, clothing and a safe place to stay. |
| Barrio Logan College Institute | San Diego, CA | $25,000 | 2025 | support BLCI's College Career and Readiness Program, which prepares underserved students to be the first in their families to attend and graduate college through year-round, no-cost after-school programs. |
| Florence Crittenton Services of Orange County Inc | Fullerton, CA | $25,000 | 2025 | provide behavioral health/child welfare services. |
| Special Olympics Southern California | Long Beach, CA | $25,000 | 2025 | fund direct program expenses and growth in the chapter. |
| Shoes That Fit | Claremont, CA | $25,000 | 2025 | distribute shoes to low-income children in Southern California. |
| Life Steps Foundation Inc | Los Angeles, CA | $25,000 | 2025 | enhance critical care and training for over 300 adults with developmental disabilities. |
| Guide Dogs for the Blind Inc | San Rafael, CA | $25,000 | 2025 | support activities in Southern California. |
| Carol's Kitchen Inc | Beaumont, CA | $25,000 | 2025 | purchase protein for lunches and assist with the operation costs such as: truck gas and maintenance, utilities and rent. |
| Lawrence Family Jewish Community Center | La Jolla, CA | $20,000 | 2025 | cover the salaries of 4 full-time staff members for 8 weeks of summer camp. |
| Happy Trails for Kids | Santa Monica, CA | $20,000 | 2025 | cover direct camp expenses: Counselors and specialty staff, camp facilities, transportation to/from camp, activity supplies, insurance, and staff training. |
| AHEAD With Horses Inc | Shadow Hills, CA | $20,000 | 2025 | create a permanent, expanded facility. |
| Homeboy Industries | Los Angeles, CA | $20,000 | 2025 | support Education and Curriculum programming that enables formerly incarcerated or gang-involved individuals to pursue goals that lead to self-sufficiency and promotes equity in access to education. |
| Foundation for Women Warriors | Vista, CA | $15,000 | 2025 | support the delivery of the Women Veteran Transition and Emergency Services program. |
| Orange County Rescue Mission Inc | Tustin, CA | $15,000 | 2025 | support the Success Center. |
| Cheerful Helpers Child and Family Study Center | Los Angeles, CA | $15,000 | 2025 | expand efforts to further develop continuum of care. |
| Mar Vista Family Center | Culver City, CA | $15,000 | 2025 | support of the organization's community-based programs and services, which address the educational, health and developmental barriers low-income families experience in building sustainable and thriving lives. |
| Switzer Learning Center | Torrance, CA | $15,000 | 2025 | aid Switzer Super Readers, providing classroom reading sets and new resources for our new school library, catering to the unique learning needs of these students. |
| Proyecto Pastoral | Los Angeles, CA | $15,000 | 2025 | expand the IMPACTO youth program. |
| Breast Cancer Solutions | Lake Forest, CA | $10,000 | 2025 | provide financial assistance for housing. |
| Orange County Adult Achievement Center | Anaheim, CA | $10,000 | 2025 | provide 12 adults with disabilities the educational support they need to take one semester of High School Diploma classes and/or college classes, resulting in better employment options, higher earning potential, and greater independence. |
| Coastal Roots Farm | Encinitas, CA | $10,000 | 2025 | cover education program costs, program scholarships, and bus transportation. |
| Forever Balboa Park | San Diego, CA | $10,000 | 2025 | support a new literacy initiative. |
support the Little Heroes League Care Coordination Program.
support Thermo Fisher Bigfoot Spectral Flow Cytometer and Cell Sorter which represents the greatest innovation in the field of research and provides exponential levels of resolution to identify rare single cells contributing to diseases.
support equipment and technology upgrades for the Del Vicario Cardiovascular Center of Excellence to improve the way in which we diagnose and treat cardiovascular care in community.
Glendale Adventist Medical Center Foundation
$300,000renovate four catheterization labs.
Salk Institute for Biological Studies
purchase an Axioscan 7 system.
Long Beach Medical Center
$250,000purchase a new laser system necessary for minimally invasive cardiovascular procedures including coronary and peripheral atherectomies, thoracic aortic aneurysm repair, endovascular abdominal aortic repair, and more.
purchase the next-generation sequencer NextSeq2000.
renovate a recently purchased facility in an unserved/underserved section of South Los Angeles to provide comprehensive services to transition violence victims from crisis to stability and on to self-sufficiency.
Mater Dei High School
$100,000support construction of a performing arts center to support the Mater Dei community as well as the broader Santa Ana and Orange County communities.
To identify and implement a new County and State compliant electronic health record (EHR) system.
support the clinical team for dementia care to vulnerable patients.
American Red Cross
$62,000purchase a new Ram ProMaster 3500.
provide current patrons with additional food support and expand the current number of patrons.
support operation of Harvest Solutions Farm.
renovate the permanent supportive housing building Euclid Villa.
Los Angeles House of Ruth
$50,000help cover the final costs of the building of a Community Building.
sustain and grow research, education, and hearing health care initiatives.
The Dragon Kim Foundation
$50,000expand opportunities for youth through equitable and inclusive entrepreneurship leadership training opportunities for high school students across Southern CA.
sustain and expand the Conejo Free Clinic's Senior Dentistry Program by supporting direct treatment, treatment supplies and advanced specialty dentures; completed care for over 400 low income seniors with no options for care.
Fallbrook Senior Citizens Service Club
$45,000buy food and pay staff for the Nutrition Program that aims to reduce both food insecurity and social isolation among older adults by offering nutritious meals, entertainment, and activities in a communal setting.
support young women and girls impacted by foster care and juvenile justice in our Short-Term Residential Therapeutic Program (STRTP), ages 13-18, and Transitional Housing Program, ages 18-25, who are pregnant and parenting.
Project Understanding of San Buenaventura
$35,000purchase a used truck to transport food donations.
purchase a panoramic radiograph and an oral surgery handpiece for dental clinic to improve access to - and quality of - oral health care for neighbors experiencing or at-risk of homelessness.
support Southern CA programming through book distribution events, ensure deploying units have equipment and supplies needed for story stations, operate the Mobile Story Station West, and train United Through Reading volunteers.
Child & Family Center
$30,000support C&FC's Domestic Violence program - the only DV program and shelter in L.A. County's 3rd largest city.
Healing California
$30,000purchase new mobile dental units.
Boys Club of Fallbrook
$30,000support new teen center project.
support the physical, emotional, mental and spiritual needs of people experiencing homelessness in Long Beach, including hot meals, clothing and a safe place to stay.
support BLCI's College Career and Readiness Program, which prepares underserved students to be the first in their families to attend and graduate college through year-round, no-cost after-school programs.
Florence Crittenton Services of Orange County Inc
$25,000provide behavioral health/child welfare services.
fund direct program expenses and growth in the chapter.
distribute shoes to low-income children in Southern California.
Life Steps Foundation Inc
$25,000enhance critical care and training for over 300 adults with developmental disabilities.
Carol's Kitchen Inc
$25,000purchase protein for lunches and assist with the operation costs such as: truck gas and maintenance, utilities and rent.
Lawrence Family Jewish Community Center
$20,000cover the salaries of 4 full-time staff members for 8 weeks of summer camp.
cover direct camp expenses: Counselors and specialty staff, camp facilities, transportation to/from camp, activity supplies, insurance, and staff training.
AHEAD With Horses Inc
$20,000create a permanent, expanded facility.
support Education and Curriculum programming that enables formerly incarcerated or gang-involved individuals to pursue goals that lead to self-sufficiency and promotes equity in access to education.
support the delivery of the Women Veteran Transition and Emergency Services program.
Cheerful Helpers Child and Family Study Center
$15,000expand efforts to further develop continuum of care.
support of the organization's community-based programs and services, which address the educational, health and developmental barriers low-income families experience in building sustainable and thriving lives.
Switzer Learning Center
$15,000aid Switzer Super Readers, providing classroom reading sets and new resources for our new school library, catering to the unique learning needs of these students.
Breast Cancer Solutions
$10,000provide financial assistance for housing.
Orange County Adult Achievement Center
$10,000provide 12 adults with disabilities the educational support they need to take one semester of High School Diploma classes and/or college classes, resulting in better employment options, higher earning potential, and greater independence.
cover education program costs, program scholarships, and bus transportation.