The Fleming Foundation concentrates its giving on neuroscience and Alzheimer's disease work, directing large, targeted gifts to support specific research projects and a regional hospital neuroscience institute. Grants are highly concentrated in the Lehigh Valley area and often made repeatedly to the same institutions, with an element of local philanthropic stewardship via a donor-advised fund. The foundation appears to prioritize translational research and institutional capacity-building in brain health over broad-based community programming.
Fleming Foundation’s largest recent grants have gone to Alzheimer’s research and a hospital-based neuroscience initiative, with $1.25 million awarded to Cure Alzheimers Fund in 2023, 2024, and 2025 and $1 million gifts each year to Lehigh Valley Hospital Network for the Fleming Neuroscience Health Institute. That pattern shows a funder focused on specific research projects and clinical neuroscience capacity rather than broad, open-ended programming. The foundation also uses donor-advised giving through Lehigh Valley Community Foundation, including a $900,000 contribution in 2023 and a $120,000 contribution in 2024. Recent grant recipients include regional nonprofit and health organizations such as Valley Youth House, United Way of Greater Lehigh Valley, Salvation Army of Allentown, and Valley Health Partners. Its grant history includes both large, repeated commitments and smaller general-fund awards, suggesting a mix of project support, institutional support, and local philanthropic stewardship. Across the recent record, the foundation’s giving is concentrated in the Lehigh Valley and tied closely to health, research, and community organizations.
In neuroscience and Alzheimer’s disease work, Fleming Foundation gave $1.25 million to Cure Alzheimers Fund for specific research projects in each of 2023, 2024, and 2025. It also supported Lehigh Valley Hospital Network with $1 million grants in 2023, 2024, and 2025 for the Fleming Neuroscience Health Institute, indicating repeated support for hospital-based neurology infrastructure. Beyond brain health, the foundation funded community nonprofits with general operating support, including $250,000 to Valley Youth House in 2024 and another $250,000 in 2025. It also gave $162,000 to United Way of Greater Lehigh Valley in 2024 and $65,000 in 2025, showing continued support for regional umbrella organizations. Smaller grants include $55,000 to DaVinci Science Center in 2025 and $40,000 to Animal Rescue League of Berks County in 2023.
Typical grants cluster around a modest middle range, with a p25 of $5,000, a median of $10,000, and a p75 of $26,250. The recent record includes repeated awards to the same organizations across multiple years, including annual support for several health and community groups as well as recurring major gifts for research. Fleming Foundation is a regular funder rather than a DAF-only vehicle, and it also makes donor-advised fund contributions through Lehigh Valley Community Foundation. The mix of very large project grants and many smaller general-fund awards suggests a dual approach: concentrated institutional commitments alongside broad local support.
$3.3M
$66.8M
$4.1M
$3.8M
Most grants fall between $5K and $26K, with a median of $10K.
25th Percentile
$5K
Median
$10K
75th Percentile
$26K
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Very concentrated: a small number of large grants, multiple repeat gifts to the same two leading recipients (research fund and regional hospital), and occasional channeling of funds through a local community foundation donor-advised fund.
Notable grantees: Cure Alzheimer's Fund, Lehigh Valley Hospital Network (Fleming Neuroscience Health Institute), Lehigh Valley Community Foundation
Giving is heavily centered in Pennsylvania, which accounts for 64% of grants and is the top state by grant count. Within the Lehigh Valley, Allentown appears frequently as a recipient city, alongside Bethlehem. The foundation also supports organizations in nearby Wilmington, Delaware, including Valley Health Partners. Outside the core region, recent grants reached Wellseley Hills, Massachusetts, through Cure Alzheimers Fund. All recipients in the recent grant list are in the United States.
The clearest patterns are Alzheimer’s disease research, neuroscience and hospital-based neurology programs, and local general operating support. Recent grants include repeated project funding for Cure Alzheimers Fund and the Fleming Neuroscience Health Institute, plus general-fund support for regional nonprofits in the Lehigh Valley.
The grant-size distribution is centered at relatively small to mid-sized awards: p25 is $5,000, the median is $10,000, and p75 is $26,250. At the same time, the foundation also makes much larger targeted gifts, including million-dollar commitments to research and health institutions.
Yes. The recent record shows repeated grants across multiple years to Cure Alzheimers Fund, Lehigh Valley Hospital Network, Valley Youth House, United Way of Greater Lehigh Valley, Valley Health Partners, Burn Prevention Network, and Miller Keystone Blood Center, among others.
It is classified as a regular funder, and its record includes donor-advised fund contributions through Lehigh Valley Community Foundation. It also makes direct grants for specific research projects, general funds, and institutional programs.
Pennsylvania receives 64% of the grants, making it the main recipient state. Recent recipients are concentrated in Allentown and Bethlehem, with additional grants to nearby Wilmington, Delaware, and a smaller number elsewhere in the United States.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| CURE ALZHEIMERS FUND | WELLSELEY HILLS, MA | $1,250,000 | 2025 | CONTRIBUTION TO SPECIFIC RESEARCH PROJECTS |
| LEHIGH VALLEY HOSPITAL NETWORK | ALLENTOWN, PA | $1,000,000 | 2025 | CONTRIBUTION TO FLEMING NEUROSCIENCE HEALTH INSTITUTE |
| VALLEY YOUTH HOUSE | BETHLEHEM, PA | $250,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| SALVATION ARMY OF ALLENTOWN | ALLENTOWN, PA | $127,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| VALLEY HEALTH PARTNERS | WILMINGTON, DE | $100,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| VALLEY HEALTH PARTNERS - VETERANS HEALTH PROGRAM | ALLENTOWN, PA | $79,885 | 2025 | CONTRIBUTION TO GENERAL FUND |
| UNITED WAY OF GREATER LEHIGH VALLEY | BETHLEHEM, PA | $65,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| DAVINCI SCIENCE CENTER | ALLENTOWN, PA | $55,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| COMMUNITY BIKE WORKS | ALLENTOWN, PA | $35,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| MILLER KEYSTONE BLOOD CENTER | ALLENTOWN, PA | $35,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| CALV - FOOD BANK - 6TH ST SHELTER | BETHLEHEM, PA | $30,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| BURN PREVENTION NETWORK | ALLENTOWN, PA | $25,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| DOGS FOR BETTER LIVES | EAST FALMOUTH, MA | $20,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| ANIMAL RESCUE LEAGUE OF BERKS COUNTY | MOHNTON, PA | $20,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| 1 LOVE 4 ANIMALS | SOUTHWESTERN, PA | $20,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| LEHIGH VALLEY HUMANE SOCIETY | ALLENTOWN, PA | $15,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| AMERICAN TRAUMA SOCIETY | FALLS CHURCH, VA | $15,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| PSPCA | PHOENIXVILLE, PA | $10,000 | 2025 | CONTRIUBTION TO GENERAL FUND |
| ALLENTOWN AREA ECUMENICAL FOOD BANK | ALLENTOWN, PA | $10,000 | 2025 | CONTRIUBTION TO GENERAL FUND |
| SCHWARZMAN ANIMAL MEDICAL CENTER | NEW YORK, NY | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| WILDLANDS CONSERVANCY | EMMAUS, PA | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| SEMPER FI FUND | QUANTICO, VA | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| BEST FRIENDS ANIMAL SOCIETY | NEW YORK, NY | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| PUPPIES BEHIND BARS | NEW YORK, NY | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| EQUI-LIBRIUM | NAZARETH, PA | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| MEALS ON WHEELS OF THE GLV | ALLENTOWN, PA | $10,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| RYERRS FARM FOR AGED EQUINES | POTTSTOWN, PA | $7,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| RAILS TO TRAILS CONSERVANCY | WASHINGTON, DC | $7,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| CAMELOT FOR CHILDREN | ALLENTOWN, PA | $7,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| TAILS OF VALOR - PAWS OF HONOR PROGRAM INC | CHAMBERSBURG, PA | $7,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| DISABLED AMERICAN VETERANS CHARITABLE SERVICE TRUST | COLD SPRING, KY | $7,500 | 2025 | CONTRIBUTION TO GENERAL FUND |
| CANCER SUPPORT COMMUNITY OF THE GLV | FALLS CHURCH, VA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| BACH CHOIR OF BETHLEHEM | BETHLEHEM, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| DAYS END FARM HORSE RESCUE | WOODBINE, MD | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| ALZHEIMERS ASSOCIATION | PHILADELPHIA, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| THE SEED FARM | EMMAUS, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| THE CAT SHACK INC | TREXLERTOWN, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| STANDARDBRED RETIREMENT FOUNDATION | CREAM RIDGE, NJ | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| BERKS NATURE CONSERVANCY | READING, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| CANINE PARTNERS FOR LIFE | COCHRANVILLE, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| SIGHTS FOR HOPE | ALLENTOWN, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| AMERICAN RED CROSS OF THE GLV | BETHLEHEM, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| MUSICWORKS | HATBORO, PA | $5,000 | 2025 | CONTRIBUTION TO GENERAL FUND |
| CURE ALZHEIMERS FUND | WELLSELEY HILLS, MA | $1,250,000 | 2024 | CONTRIBUTION TO SPECIFIC RESEARCH PROJECTS |
| LEHIGH VALLEY HOSPITAL NETWORK | ALLENTOWN, PA | $1,000,000 | 2024 | CONTRIBUTION TO FLEMING NEUROSCIENCE HEALTH INSTITUTE |
| VALLEY YOUTH HOUSE | BETHLEHEM, PA | $250,000 | 2024 | CONTRIBUTION TO GENERAL FUND |
| UNITED WAY OF GREATER LEHIGH VALLEY | BETHLEHEM, PA | $162,000 | 2024 | CONTRIBUTION TO GENERAL FUND |
| LEHIGH VALLEY COMMUNITY FOUNDATION | ALLENTOWN, PA | $120,000 | 2024 | CONTRIBUTION TO DONOR ADVISED FUND |
| VALLEY HEALTH PARTNERS | WILMINGTON, DE | $100,000 | 2024 | CONTRIBUTION TO GENERAL FUND |
| MILLER KEYSTONE BLOOD CENTER | ALLENTOWN, PA | $35,000 | 2024 | CONTRIBUTION TO GENERAL FUND |
LEHIGH VALLEY HOSPITAL NETWORK
$1,000,000CONTRIBUTION TO FLEMING NEUROSCIENCE HEALTH INSTITUTE
SALVATION ARMY OF ALLENTOWN
$127,500CONTRIBUTION TO GENERAL FUND
VALLEY HEALTH PARTNERS
$100,000CONTRIBUTION TO GENERAL FUND
VALLEY HEALTH PARTNERS - VETERANS HEALTH PROGRAM
CONTRIBUTION TO GENERAL FUND
UNITED WAY OF GREATER LEHIGH VALLEY
$65,000CONTRIBUTION TO GENERAL FUND
DAVINCI SCIENCE CENTER
$55,000CONTRIBUTION TO GENERAL FUND
MILLER KEYSTONE BLOOD CENTER
$35,000CONTRIBUTION TO GENERAL FUND
CALV - FOOD BANK - 6TH ST SHELTER
$30,000CONTRIBUTION TO GENERAL FUND
BURN PREVENTION NETWORK
$25,000CONTRIBUTION TO GENERAL FUND
DOGS FOR BETTER LIVES
$20,000CONTRIBUTION TO GENERAL FUND
ANIMAL RESCUE LEAGUE OF BERKS COUNTY
$20,000CONTRIBUTION TO GENERAL FUND
1 LOVE 4 ANIMALS
$20,000CONTRIBUTION TO GENERAL FUND
LEHIGH VALLEY HUMANE SOCIETY
$15,000CONTRIBUTION TO GENERAL FUND
AMERICAN TRAUMA SOCIETY
$15,000CONTRIBUTION TO GENERAL FUND
PSPCA
$10,000CONTRIUBTION TO GENERAL FUND
ALLENTOWN AREA ECUMENICAL FOOD BANK
$10,000CONTRIUBTION TO GENERAL FUND
MEALS ON WHEELS OF THE GLV
$10,000CONTRIBUTION TO GENERAL FUND
RYERRS FARM FOR AGED EQUINES
$7,500CONTRIBUTION TO GENERAL FUND
CAMELOT FOR CHILDREN
$7,500CONTRIBUTION TO GENERAL FUND
TAILS OF VALOR - PAWS OF HONOR PROGRAM INC
$7,500CONTRIBUTION TO GENERAL FUND
CONTRIBUTION TO GENERAL FUND
CANCER SUPPORT COMMUNITY OF THE GLV
$5,000CONTRIBUTION TO GENERAL FUND
ALZHEIMERS ASSOCIATION
$5,000CONTRIBUTION TO GENERAL FUND
THE SEED FARM
$5,000CONTRIBUTION TO GENERAL FUND
THE CAT SHACK INC
$5,000CONTRIBUTION TO GENERAL FUND
BERKS NATURE CONSERVANCY
$5,000CONTRIBUTION TO GENERAL FUND
AMERICAN RED CROSS OF THE GLV
$5,000CONTRIBUTION TO GENERAL FUND
MUSICWORKS
$5,000CONTRIBUTION TO GENERAL FUND
LEHIGH VALLEY HOSPITAL NETWORK
$1,000,000CONTRIBUTION TO FLEMING NEUROSCIENCE HEALTH INSTITUTE
UNITED WAY OF GREATER LEHIGH VALLEY
$162,000CONTRIBUTION TO GENERAL FUND
LEHIGH VALLEY COMMUNITY FOUNDATION
$120,000CONTRIBUTION TO DONOR ADVISED FUND
VALLEY HEALTH PARTNERS
$100,000CONTRIBUTION TO GENERAL FUND
MILLER KEYSTONE BLOOD CENTER
$35,000CONTRIBUTION TO GENERAL FUND