| CHARITIES AID FOUNDATION AMERICA | ALEXANDRIA, VA | $1,523,928 | 2025 | GENERAL OPERATING SUPPORT |
| THE THORACIC SURGERY FOUNDATION | WASHINGTON, IL | $550,000 | 2025 | 2025 TSF EVERY HEARTBEAT MATTERS PROGRAM |
| PYXERA GLOBAL INC | WASHINGTON, DC | $370,000 | 2025 | EVERY HEARTBEAT MATTERS PRO BONO CORPS |
| UNITED WAY ORANGE COUNTY | IRVINE, CA | $356,097 | 2025 | GENERAL OPERATING SUPPORT |
| MATCHING GIFTS US - ORANGE COUNTY | IRVINE, CA | $305,879 | 2025 | GENERAL OPERATING SUPPORT |
| CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER | CINCINNATI, OH | $300,000 | 2025 | THE ACT REGISTRY: EXPANDING GLOBAL PARTNERSHIPS AND IMPACT |
| MATCHING GIFTS US - OTHER | IRVINE, CA | $258,534 | 2025 | GENERAL OPERATING SUPPORT |
| AMERICAN ASSOCIATION FOR THORACIC SURGERY | BEVERLY, MA | $250,000 | 2025 | AATS FOUNDATION EVERY HEARTBEAT MATTERS INITIATIVE |
| LUCILE PACKARD CHLIDREN'S HOSPITAL STANFORD | PALO ALTO, CA | $250,000 | 2025 | COMMUNITY GRANT |
| PATIENT ADVOCATE FOUNDATION INC | HAMPTON, VA | $250,000 | 2025 | STRUCTURAL HEART DISEASE CARELINE (SHDCL), HEART VALVE FINANCIAL AID FUND (HVFAF), AND SUMMIT |
| STANFORD BYERS CENTER FOR BIODESIGN | STANFORD, CA | $232,000 | 2025 | STANFORD BYERS CENTER FOR BIODESIGN |
| UNITED WAY ORANGE COUNTY | IRVINE, CA | $207,938 | 2025 | GENERAL OPERATING SUPPORT |
| HEART TO HEART GLOBAL CARDIAC CARE | OAKLAND, CA | $200,000 | 2025 | COSTA RICA NATIONWIDE CARDIAC CARE CAMPAIGN (2020-2035) |
| AMERICAN COLLEGE OF CARDIOLOGY FOUNDATION | WASHINGTON, DC | $190,000 | 2025 | INNOVATING CLINICIAN TRAINING IN ECHO FOR THE IDENTIFICATION AND TREATMENT OF VHD |
| CHILDREN'S NATIONAL HOSPITAL | WASHINGTON, DC | $170,000 | 2025 | IMPROVING DETECTION, TREATMENT AND RECOVERY IN UNDERSERVED PATIENTS WITH STRUCTURAL HEART DISEASE ACROSS THE LIFESPAN IN BRAZIL |
| GIVE2ASIA | OAKLAND, CA | $157,093 | 2025 | GENERAL OPERATING SUPPORT |
| PROGRAM FOR APPROPRIATE TECHNOLOGY IN HEALTH (PATH) | SEATTLE, WA | $150,000 | 2025 | YOUNG HEARTS, STRONG FUTURES |
| HEINEMAN-ROBICSEK FOUNDATION | CHARLOTTE, NC | $150,000 | 2025 | CENTRAL AMERICAN HEART |
| CEO LEADERSHIP ALLIANCE ORANGE COUNTY | LAGUNA BEACH, CA | $150,000 | 2025 | BUSINESS AND ECONOMIC DEVELOPMENT FOR ORANGE COUNTY, CA |
| EMERGENCY USA-LIFE SUPPORT FOR CIVILIAN VICTIMS OF WAR AND POVERTY | NEW YORK, NY | $150,000 | 2025 | THE SALAM CENTER FOR CARDIAC SURGERY, KHARTOUM, SUDAN |
| AMERICAN HEART ASSOCIATION INC | DALLAS, TX | $135,000 | 2025 | AHA HEART BALL - FUNDRAISING SUPPORT AF, WM, LP |
| INTERNATIONAL CARDIAC ALLIANCE INC (HAITI CARDIAC ALLIANCE) | BURLINGTON, VT | $125,000 | 2025 | USING COLLABORATION AND DATA MANAGEMENT TO OVERCOME BARRIERS TO SHD CARE |
| UNIVERSITY OF CALIFORNIA IRVINE FOUNDATION (CIRC) | IRVINE, CA | $100,000 | 2025 | ENGINEERING IN CARDIOVASCULAR HEALTH EQUITY BY FACULTY RECRUITING AND UNDERGRADUATE RESEARCH |
| ARRHYTHMIA ALLIANCE | HILTON HEARD, SC | $100,000 | 2025 | A-A HEARTS OF GHANA |
| MITRAL FOUNDATION | NEW YORK, NY | $100,000 | 2025 | INTERNATIONAL DEVELOPMENT PROJECT |
| MAP INTERNATIONAL | BRUNSWICH, GA | $100,000 | 2025 | EDWARDS LIFESCIENCES DONATION PROGRAM WITH MAP INTERNATIONAL |
| TEAM HEART | MILTON, MA | $100,000 | 2025 | STRENGTHENING IDENTIFICATION AND TREATMENT OF STRUCTURAL HEART DISEASE IN THE COMMUNITY TO THE REFERRAL HOSPITAL FOR SPECIALTY CARE |
| OCTANE FOUNDATION FOR INNOVATION | NEWPORT BEACH, CA | $90,000 | 2025 | NON-PROFIT ACCELERATOR (NPA) & NPA 2.0 BUILDING CAPACITY, IMPROVING SUSTAINABILITY AND INCREASING COMMUNITY IMPACT |
| UNIVERSITY OF SOUTHERN CALIFORNIA | LOS ANGELES, CA | $75,000 | 2025 | EDWARDS LIFESCIENCES DOCTORAL FELLOWSHIP AT THE USC SCHAEFFER CENTER |
| THE UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $70,000 | 2025 | SAVE MI-HEARTS |
| SCHOLARSHIP AMERICA | SAINT PETER, MN | $57,500 | 2025 | SCHOLARSHIP PROGRAM |
| ST LUKE'S HEALTH CARE FOUNDATION | WHEATON, IL | $50,000 | 2025 | RHEUMATIC HEART DISEASE SCREENING AND TREATMENT PROGRAM |
| RILEY CHILDREN'S FOUNDATION | INDIANAPOLIS, IN | $50,000 | 2025 | PROVIDING ACCESS TO HEALTHCARE: SYSTEMATIC DEVELOPMENT OF CARDIAC SURGERY AT MOI UNIVERSITY |
| CARDIOSTART INTERNATIONAL | ST PETERSBURG, FL | $45,000 | 2025 | HELPING HEARTS NIGERIA |
| ALTAMED HEALTH SERVICES CORP | COMMERCE, CA | $35,000 | 2025 | ALTAMEDS EDUCATION AND TREATMENT OF STRUCTURAL HEART DISEASE PROGRAM |
| WORKING WARDROBES FOR A NEW START | SANTA ANA, CA | $30,000 | 2025 | REBUILDING CAREERS FOR VETERANS |
| FOUNDATION FOR HOSPITAL ART | WOODSTOCK, GA | $27,700 | 2025 | GENERAL OPERATING SUPPORT |
| MATCHING GIFTS UTAH | IRVINE, CA | $27,567 | 2025 | GENERAL OPERATING SUPPORT |
| AMERICAN RED CROSS - ORANGE COUNTY | SANTA ANA, CA | $25,000 | 2025 | BLOOD SAVES LIVES: GENERAL OPERATIONS |
| MENDING KIDS INTERNATIONAL | WOODLAND HILLS, CA | $25,000 | 2025 | INTERNATIONAL SEPTOSTEMY PROGRAM (ISP) |
| UCLA BIODESIGN | LOS ANGELES, CA | $25,000 | 2025 | UCLA BIODESIGN |
| CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER | CINCINNATI, OH | $25,000 | 2025 | HEART MONTH - SUPPORT FOR FORT APACHE INDIAN RESERVATION IN AZ |
| ST LUKE'S HEALTH FOUNDATION | WHEATON, IL | $25,000 | 2025 | HEART MONTH - CARDIAC CARE IN ETHIOPIA |
| DISCOVERY SCIENCE CENTER | SANTA ANA, CA | $25,000 | 2025 | EDWARDS LIFE SCIENCES FEBRUARY HEART MONTH AT DISCOVERY CUBE |
| MENDING KIDS INTERNATIONAL | WOODLAND HILLS, CA | $25,000 | 2025 | HEARTBEATS |
| UNIVERSITY OF CALIFORNIA IRVINE FOUNDATION | IRVINE, CA | $25,000 | 2025 | UCI-OC ALLIANCE SCHOLARSHIPS |
| ONEOC | SANTA ANA, CA | $25,000 | 2025 | ACCELERATING NONPROFIT SUCCESS- SIGNATURE EVENT SERIES SPONSORSHIP |
| CAMP DEL CORAZON | HOLLYWOOD, CA | $25,000 | 2025 | HAPPY HEART FESTIVAL |
| UNIVERSITY OF CALIFORNIA IRVINE FOUNDATION | IRVINE, CA | $25,000 | 2025 | UC IRVINE SCHOOL OF SOCIAL SCIENCES WOMEN OF THE DEAN'S LEADERSHIP SOCIETY FELLOWSHIP - LEADHER |
| E4E RELIEF | CHARLOTTE, NC | $25,000 | 2025 | HEART 2 HEART EMPLOYEE RELIEF FUND |
