The E S Prentiss Foundation concentrates large, targeted gifts to a small number of institutions primarily in the Cleveland/Akron region despite being based in Pittsburgh. Its funding emphasizes K–12 Catholic secondary education, major hospital systems and clinical/medical research (notably cardiovascular care), and patient-centered hospice services. Grants are typically substantial and multi-award commitments that support both general operating needs and specific programmatic initiatives.
E S Prentiss Foundation-ir gives large, repeated grants to a small set of institutions in the Cleveland area, with Cleveland-based University Hospitals Health System and St Martin De Porres High School appearing multiple times in the recent record. The foundation’s recent awards show a clear preference for substantial commitments rather than many small gifts: one $1,000,000 grant supported University Hospitals Health System’s Eye Institute, while St Martin De Porres High School received $675,000 in 2024 and another $675,000 in 2023 for support of its center. Alongside those anchor commitments, the foundation has also backed Case Western Reserve University, Hospice of the Western Reserve, Mercy Health, and Metrohealth Foundation. Its grantmaking reaches across education, medical care, and patient services, with especially visible support for Catholic secondary education, hospital systems, cardiovascular research, hospice care, and community health programs. The pattern is one of targeted institutional funding, often paired with specific program or operating purposes, rather than broad small-dollar dispersal.
In education, the foundation has backed St Martin De Porres High School with $675,000 in both 2024 and 2023 for support of its center, and later provided $150,000 in 2025 for the same purpose. In health care delivery, it gave $250,000 to Neighborhood Health Care Inc in 2024 for a new health center and $250,000 in 2023 to support primary care for low-income patients. Clinical research is another visible thread: Case Western Reserve University received $400,000 in 2025 and $400,000 in 2024 for the Strong Heart program, after a $500,000 general-support grant in 2023. Patient-centered hospice services also appear in multiple years through Hospice of the Western Reserve, which received $400,000 in 2025 and $200,000 in 2024 and 2023 for its 24/7 immediate care work.
Typical grants cluster at a substantial size, with the middle of the distribution at $50,000, while the 25th percentile is $25,000 and the 75th percentile is $100,000. The recent record shows repeated awards to the same organizations across multiple years, including St Martin De Porres High School, University Hospitals Health System, Case Western Reserve University, Hospice of the Western Reserve, Neighborhood Health Care Inc, Metrohealth Foundation, and May Dugan Center. That repeat pattern points to ongoing institutional relationships rather than one-time project-only giving. The foundation funds organizations, not individuals, and there is no program-related investing activity reported.
$4.8M
$72.2M
$6.8M
$5.1M
Most grants fall between $25K and $100K, with a median of $50K.
25th Percentile
$25K
Median
$50K
75th Percentile
$100K
About 0% of grants go to recipients in OH.
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Concentrated, large-dollar grants to a handful of repeat grantees—mix of unrestricted/general operating support and targeted program funding—focused regionally rather than widely distributed.
Notable grantees: University Hospitals Health System, St. Martin de Porres High School, Case Western Reserve University, Hospice of the Western Reserve
Giving is highly concentrated in Ohio, which is the top state by grant count. Most recent grants land in Cleveland, with additional awards in Lorain and Middlefield; one grant in the recent list went to Irvine, California. The recipient-country distribution is entirely U.S.-based, with 142 grants in the United States and none listed elsewhere. The pattern reflects a regional portfolio centered on Northeast Ohio institutions.
The grant-size distribution is weighted toward larger awards: the 25th percentile is $25,000, the median is $50,000, and the 75th percentile is $100,000. Recent grants also include several six- and seven-figure commitments, including awards at $250,000, $400,000, $675,000, and $1,000,000.
Recent grants show support for Catholic secondary education, hospital systems and clinical research, hospice and patient-centered end-of-life care, primary care access, autism services, and health-related facility or program support. Named examples include St Martin De Porres High School, University Hospitals Health System, Case Western Reserve University, and Hospice of the Western Reserve.
Yes. Several recipients appear across multiple years in the recent grants list. Examples include St Martin De Porres High School in 2023, 2024, and 2025; Case Western Reserve University in 2023, 2024, and 2025; University Hospitals Health System in 2023, 2024, and 2025; and Hospice of the Western Reserve in 2023, 2024, and 2025.
The top state by grant count is Ohio, and recent grants are concentrated in Cleveland with additional awards in Lorain and Middlefield. The grant list also includes one recipient in Irvine, California, while the overall country distribution is entirely U.S.-based.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| UNIVERSITY HOSPITALS HEALTH SYSTEM | CLEVELAND, OH | $1,000,000 | 2025 | EYE INSTITUTE |
| CASE WESTERN RESERVE UNIVERSITY | CLEVELAND, OH | $400,000 | 2025 | STRONG HEART PROGRAM, |
| HOSPICE OF THE WESTERN RESERVE | CLEVELAND, OH | $400,000 | 2025 | PATIENT-CENTERED 24/7 IMMED |
| BELLEFAIRE JCB | SHARKER HEIGHTS, OH | $250,000 | 2025 | SUPPORT FOR BLUESTONE |
| MERCY HEALTH | LORAIN, OH | $250,000 | 2025 | MAMMOGRAM VAN |
| DDC CLINIC | MIDDLEFIELD, OH | $200,000 | 2025 | GENETIC CARDIAC CONDITIONS |
| METROHEALTH FOUNDATION | CLEVELAND, OH | $200,000 | 2025 | SUPPORTING THE AUTISM |
| ST MARTIN DE PORRES HIGH SCHOOL | CLEVELAND, OH | $150,000 | 2025 | SUPPORT FOR CENTER OF |
| NEIGHBORHOOD HEALTH CARE INC | CLEVELAND, OH | $145,000 | 2025 | NEW HEALTH CENTER |
| MAY DUGAN CENTER | CLEVELAND, OH | $125,000 | 2025 | UPDATE AND RENOVATION OF |
| THE CENTERS | CLEVELAND, OH | $100,000 | 2025 | INTEGRATED HEALTH AND |
| ACHIEVEMENT CENTERS FOR CHILDREN | CLEVELAND, OH | $100,000 | 2025 | OCCUPATIONAL, PHYSICAL & |
| KENT STATE UNIVERSITY FOUNDATION | AKRON, OH | $100,000 | 2025 | MOBILE WELLNESS PROGRAM |
| CLEVELAND HEARING AND SPEECH CENTER | CLEVELAND, OH | $100,000 | 2025 | BUILDING NAMING GIFT |
| BALDWIN WALLACE UNIVERSITY | BEREA, OH | $78,000 | 2025 | TRAINING FOR NURSING AND PA |
| PLANNED PARENTHOOD | CLEVELAND HTS, OH | $75,000 | 2025 | CORE OPERATING SUPPORT |
| LAKE COUNTY FREE CLINIC | PAINESVILLE, OH | $75,000 | 2025 | EXPANDING ACCESS TO CARE; |
| CUYAHOGA COMMUNITY COLLEGE FOUNDATION | CLEVELAND, OH | $75,000 | 2025 | MODERNIZE STERILE |
| ST VINCENT CHARITY MEDICAL CENTER | CLEVELAND, OH | $70,000 | 2025 | GERIATRIC BEHAVIORAL HEALTH |
| AMERICAN RED CROSS NORTHERN OHIO | CLEVELAND, OH | $58,000 | 2025 | PURCHASE OF NEW WALK-IN BIO |
| CARE ALLIANCE HEALTH CENTER | CLEVELAND, OH | $50,000 | 2025 | REDUCING BARRIERS TO HEALTH |
| CLEVELAND SIGHT CENTER | CLEVELAND, OH | $50,000 | 2025 | SERVICE FOR LOW INCOME |
| JOSEPH'S HOME | CLEVELAND, OH | $50,000 | 2025 | NEW SPACE FOR JOSEPH'S HOME |
| MENTAL HEALTH SERVICES FOR HOMELESS | CLEVELAND, OH | $50,000 | 2025 | INTEGRATED HEALTH CARE FOR |
| NEW AVENUES TO INDEPENDENCE | CLEVELAND, OH | $50,000 | 2025 | MEDICAL GAP PROJECT |
| PROVIDENCE HOUSE | CLEVELAND, OH | $50,000 | 2025 | SUPPORT OF GIVING HOPE FOR |
| JEWISH FAMILY SERVICE ASSOCIATION | PEPPER PIKE, OH | $50,000 | 2025 | ALZHEIMER & DEMENTIA |
| CLEVELAND RAPE CRISIS CENTER | CLEVELAND, OH | $50,000 | 2025 | SUPPORT OF LAUNCHING |
| AKRON CHILDRENS HOSPITAL | AKRON, OH | $50,000 | 2025 | DIAGNOSTIC EQUIPMENT FOR |
| MOBILEMED 1 FOUNDATION | CLEVELAND, OH | $45,000 | 2025 | CONNECT NE OHIO LOW INC |
| HANNA PERKINS CENTER | SHAKER HEIGHTS, OH | $32,000 | 2025 | CLOSING THE GAP; MOVING |
| UNITED CEREBRAL PALSY ASSOCIATION | CLEVELAND, OH | $30,000 | 2025 | LEAFBRIDGE THERAPY & CASE |
| FAR WEST CENTER | WESTLAKE, OH | $28,000 | 2025 | MENTAL HEALTH PREVENTION & |
| SALVATION ARMY NORTHEAST OHIO | CLEVELAND, OH | $25,000 | 2025 | ABUSE RECOVERY PROGRAM |
| MEDWORKS | CLEVELAND, OH | $25,000 | 2025 | SUPPORTING THE MOBILE |
| GREATER CLEVELAND FOOD BANK | CLEVELAND, OH | $25,000 | 2025 | SUPPORT FOR FOOD AS |
| CLEVELAND CENTER FOR ARTS | CLEVELAND, OH | $25,000 | 2025 | WORKFORCE TRAINING FOR |
| IN STEPS WITH HORSES | CHAGRIN FALLS, OH | $25,000 | 2025 | SUPPORT FOR EQUINE |
| FIELDSTONE FARM THERAPEUTIC | CHAGRIN FALLS, OH | $20,000 | 2025 | FINANCIAL ASSISTANCE FOR |
| FAMILY PROMISE OF GREATER CLEVELAND | CLEVELAND, OH | $20,000 | 2025 | HEALTH EDUCATION & SUPPORT |
| HOPEWELL | MIDDLEFIELD, OH | $15,000 | 2025 | FEE ASSISTANCE FOR |
| LET'S GET REAL INC | LORAIN, OH | $10,000 | 2025 | COMMUNITY INDEPENDENT |
| EPILEPSY ASSOCATION | CLEVELAND, OH | $10,000 | 2025 | HEALTH CASE MANAGEMENT |
| PROJECT HOPE OF CLEVELAND ST ALOYSIUS CHURCH | CLEVELAND, OH | $10,000 | 2025 | SAFETY AND EDUCATION FOR |
| FOSTERING HOPE OHIO | PEPPER PIKE, OH | $10,000 | 2025 | TRAUMA INFORMED THERAPEUTIC |
| FLYING HORSE FARMS | MT GILEAD, OH | $10,000 | 2025 | PSYCHOSOCIAL SUPPORT FOR |
| LINKING EMPLOYMENT ABILITIES AND POTENTIAL ( LEAP ) | CLEVELAND, OH | $10,000 | 2025 | TRANSITION, DIVERSION & |
| ST MARTIN DE PORRES HIGH SCHOOL | CLEVELAND, OH | $675,000 | 2024 | SUPPORT FOR CENTER OF |
| CASE WESTERN RESERVE UNIVERSITY | CLEVELAND, OH | $400,000 | 2024 | STRONG HEART PROGRAM, |
| UNIVERSITY HOSPITALS HEALTH SYSTEM | CLEVELAND, OH | $350,000 | 2024 | EYE INSTITUTE |
UNIVERSITY HOSPITALS HEALTH SYSTEM
$1,000,000EYE INSTITUTE
CASE WESTERN RESERVE UNIVERSITY
$400,000STRONG HEART PROGRAM,
MERCY HEALTH
$250,000MAMMOGRAM VAN
DDC CLINIC
$200,000GENETIC CARDIAC CONDITIONS
MAY DUGAN CENTER
$125,000UPDATE AND RENOVATION OF
THE CENTERS
$100,000INTEGRATED HEALTH AND
KENT STATE UNIVERSITY FOUNDATION
$100,000MOBILE WELLNESS PROGRAM
BALDWIN WALLACE UNIVERSITY
$78,000TRAINING FOR NURSING AND PA
PLANNED PARENTHOOD
$75,000CORE OPERATING SUPPORT
CUYAHOGA COMMUNITY COLLEGE FOUNDATION
$75,000MODERNIZE STERILE
AMERICAN RED CROSS NORTHERN OHIO
$58,000PURCHASE OF NEW WALK-IN BIO
CARE ALLIANCE HEALTH CENTER
$50,000REDUCING BARRIERS TO HEALTH
CLEVELAND SIGHT CENTER
$50,000SERVICE FOR LOW INCOME
JOSEPH'S HOME
$50,000NEW SPACE FOR JOSEPH'S HOME
NEW AVENUES TO INDEPENDENCE
$50,000MEDICAL GAP PROJECT
AKRON CHILDRENS HOSPITAL
$50,000DIAGNOSTIC EQUIPMENT FOR
MOBILEMED 1 FOUNDATION
$45,000CONNECT NE OHIO LOW INC
HANNA PERKINS CENTER
$32,000CLOSING THE GAP; MOVING
UNITED CEREBRAL PALSY ASSOCIATION
$30,000LEAFBRIDGE THERAPY & CASE
FAR WEST CENTER
$28,000MENTAL HEALTH PREVENTION &
SALVATION ARMY NORTHEAST OHIO
$25,000ABUSE RECOVERY PROGRAM
MEDWORKS
$25,000SUPPORTING THE MOBILE
CLEVELAND CENTER FOR ARTS
$25,000WORKFORCE TRAINING FOR
IN STEPS WITH HORSES
$25,000SUPPORT FOR EQUINE
FIELDSTONE FARM THERAPEUTIC
$20,000FINANCIAL ASSISTANCE FOR
LET'S GET REAL INC
$10,000COMMUNITY INDEPENDENT
EPILEPSY ASSOCATION
$10,000HEALTH CASE MANAGEMENT
PROJECT HOPE OF CLEVELAND ST ALOYSIUS CHURCH
$10,000SAFETY AND EDUCATION FOR
FOSTERING HOPE OHIO
$10,000TRAUMA INFORMED THERAPEUTIC
LINKING EMPLOYMENT ABILITIES AND POTENTIAL ( LEAP )
$10,000TRANSITION, DIVERSION &
CASE WESTERN RESERVE UNIVERSITY
$400,000STRONG HEART PROGRAM,
UNIVERSITY HOSPITALS HEALTH SYSTEM
$350,000EYE INSTITUTE