Fund and accelerate translational research to develop safer, more effective treatments for children, adolescents and young adults with cancer and move promising therapies quickly into clinical trials.
CureSearch for Children's Cancer concentrates on translational research that moves promising pediatric cancer therapies toward clinical trials. Its recent grants show a strong emphasis on large, multi-year awards to major research hospitals and universities, including MD Anderson Cancer Center, Massachusetts General Hospital, and Childrens Hospital of Philadelphia. The foundation backs work across pediatric cancer research and treatment development, with a clear preference for projects that can shift from pre-clinical studies into early-phase clinical testing. The portfolio reflects a disease-specific strategy rather than broad oncology support. Recent funding includes repeated support for pediatric cancer research institutions working on high-risk areas such as brain tumors, sarcomas, leukemias, and neuroblastoma. Grants also reach organizations involved in trial development and field-building, such as St Baldrick's Foundation Inc. Across the recent list, the pattern is consistent: CureSearch funds research teams and trial infrastructure that are positioned to advance children, adolescents, and young adults with cancer toward safer and more effective treatments.
In translational research, CureSearch gave $703,489 to MD Anderson Cancer Center for therapeutic work, and $334,000 to Childrens Hospital of Philadelphia for therapeutic work. It also supported Massachusetts General Hospital with $269,000 for therapeutic work, showing repeated backing for large academic medical centers. The foundation also invests in early-career research. It gave $75,000 to Baylor College of Medicine for therapeutic work and $149,019 to Yale University for therapeutic work, both within a portfolio that includes Young Investigator awards and early-stage research support. Clinical trial development is another clear theme. CureSearch awarded $500,000 to the University of Alabama at Birmingham and $75,000 to Connecticut Childrens Medical Center for therapeutic work, alongside grants to institutions working on phase I and phase II pediatric oncology studies. These awards align with its focus on moving promising therapies into the clinic.
Typical awards cluster around six figures: p25 is $75,000, median grant size is $100,000, and p75 is $269,000. The recent grant list also includes several larger awards above $300,000, indicating capacity for substantial project funding. The pattern appears recurring rather than one-off, with institutions such as Childrens Hospital of Philadelphia, Massachusetts General Hospital, Augusta University Medical College of Georgia, and Baylor College of Medicine appearing in multiple years. CureSearch is an operating-style grantmaker focused on program-specific, outcome-driven research support. Several active programs accept unsolicited applications, including Young Investigator Awards, Acceleration Initiative Awards, and Catapult Award.
$2.7M
$7.2M
$5M
$6.1M
Most grants fall between $75K and $269K, with a median of $100K.
25th Percentile
$75K
Median
$100K
75th Percentile
$269K
About 3% of grants go to recipients in CA.
KAY KOEHLER
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CureSearch gives nationally, and every recent grant in the provided list went to a U.S. recipient. By count, Massachusetts is the top state of giving, while Maryland received 3% of grants. Recent recipients are concentrated in major research hubs such as Houston, Philadelphia, Boston, Los Angeles, Birmingham, and Atlanta. The strongest city-level presence in the list includes Philadelphia through Childrens Hospital of Philadelphia, Boston through Massachusetts General Hospital, and Houston through MD Anderson Cancer Center and Baylor College of Medicine.
The foundation funds translational research, pre-clinical cancer research, and early-phase clinical trials. Its active program areas include pediatric glioma, high-grade glioma, Ewing sarcoma, acute myeloid leukemia, neuroblastoma, atypical teratoid rhabdoid tumor, osteosarcoma, and pediatric recurrent brain tumors.
Typical awards center on six figures. The grant-size distribution is $75,000 at the 25th percentile, $100,000 at the median, and $269,000 at the 75th percentile.
Yes, several active programs accept unsolicited applications. Those include the Acceleration Initiative Awards, Young Investigator Awards, Young Investigator Program, Catapult Award, and Clinical Trial Funding.
The foundation gives nationally across the United States, with Massachusetts as the top state by grant count. Maryland accounts for 3% of grants, and recent recipients include institutions in Houston, Philadelphia, Boston, Los Angeles, Birmingham, and Atlanta.
Recent grantees include MD Anderson Cancer Center, Childrens Hospital of Philadelphia, Massachusetts General Hospital, University of Alabama at Birmingham, Augusta University Medical College of Georgia, and Baylor College of Medicine. All of the grants in the provided recent list went to U.S. recipients.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| MD ANDERSON CANCER CENTER | HOUSTON, TX | $703,489 | 2025 | THERAPEUTIC |
| CEDARS SINAI MEDICAL CENTER | LOS ANGELES, CA | $334,000 | 2025 | THERAPEUTIC |
| WASHINGTON UNIVERSITY | ST LOUIS, MO | $333,334 | 2025 | THERAPEUTIC |
| CHILDRENS HOSPITAL OF PHILADELPHIA | PHILADELPHIA, PA | $332,000 | 2025 | THERAPEUTIC |
| AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA | AUGUSTA, GA | $200,000 | 2025 | THERAPEUTIC |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $166,000 | 2025 | THERAPEUTIC |
| UNIVERSITY OF CALIFORNIA (UCLA) | LOS ANGELES, CA | $155,192 | 2025 | THERAPEUTIC |
| ST BALDRICK'S FOUNDATION INC | MONROVIA, CA | $103,000 | 2025 | THERAPEUTIC |
| CHILDREN'S HOSPITAL LOS ANGELES | LOS ANGELES, CA | $75,000 | 2025 | THERAPEUTIC |
| CONNECTICUT CHILDRENS MEDICAL CENTER | HARTFORD, CT | $75,000 | 2025 | THERAPEUTIC |
| EMORY UNIVERSITY | ATLANTA, GA | $75,000 | 2025 | — |
| BAYLOR COLLEGE OF MEDICINE | HOUSTON, TX | $75,000 | 2025 | THERAPEUTIC |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | NEW YORK, NY | $37,500 | 2025 | THERAPEUTIC |
| UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER | CLEVELAND, OH | $37,500 | 2025 | THERAPEUTIC |
| AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA | AUGUSTA, GA | $400,000 | 2024 | THERAPEUTIC |
| CHILDRENS HOSPITAL OF PHILADELPHIA | PHILADELPHIA, PA | $334,000 | 2024 | THERAPEUTIC |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | BIRMINGHAM, AL | $250,000 | 2024 | THERAPEUTIC |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $167,000 | 2024 | THERAPEUTIC |
| YALE UNIVERSITY | NEW HAVEN, CT | $149,019 | 2024 | THERAPEUTIC |
| ST BALDRICK'S FOUNDATION INC | MONROVIA, CA | $100,000 | 2024 | THERAPEUTIC |
| UNIVERSITY OF COLORADO | DENVER, CO | $89,850 | 2024 | THERAPEUTIC |
| UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER | CLEVELAND, OH | $75,000 | 2024 | THERAPEUTIC |
| BAYLOR COLLEGE OF MEDICINE | HOUSTON, TX | $75,000 | 2024 | THERAPEUTIC |
| ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | NEW YORK, NY | $75,000 | 2024 | THERAPEUTIC |
| CONNECTICUT CHILDRENS MEDICAL CENTER | HARTFORD, CT | $75,000 | 2024 | THERAPEUTIC |
| UNIVERSITY OF FLORIDA | GAINESVILLE, FL | $625,000 | 2023 | THERAPEUTIC |
| UNIVERSITY OF ALABAMA AT BIRMINGHAM | BIRMINGHAM, AL | $500,000 | 2023 | THERAPEUTIC |
| CHILDRENS HOSPITAL OF PHILADELPHIA | PHILADELPHIA, PA | $334,000 | 2023 | THERAPEUTIC |
| MASSACHUSETTS GENERAL HOSPITAL | BOSTON, MA | $269,000 | 2023 | THERAPEUTIC |
| AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA | AUGUSTA, GA | $100,000 | 2023 | THERAPEUTIC |
| UNIVERSITY COLORADO | DENVER, CO | $88,900 | 2023 | THERAPEUTIC |
| BAYLOR COLLEGE OF MEDICINE | HOUSTON, TX | $75,000 | 2023 | THERAPEUTIC |
| CONNETICUT CHILDRENS MEDICAL CENTER | HARTFORD, CT | $75,000 | 2023 | THERAPEUTIC |
| NATIONAL INSTITUTES OF HEALTH | BETHESDA, MS | $65,000 | 2023 | THERAPEUTIC |
| UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON | HOUSTON, TX | $50,000 | 2023 | THERAPEUTIC |
| JOHNS HOPKINS | BALTIMORE, MD | $37,500 | 2023 | THERAPEUTIC |
| MEMORIAL SLOAN KETTERING CANCER CENTER | NEW YORK, NY | $37,500 | 2023 | THERAPEUTIC |
MD ANDERSON CANCER CENTER
$703,489THERAPEUTIC
CHILDRENS HOSPITAL OF PHILADELPHIA
$332,000THERAPEUTIC
AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA
$200,000THERAPEUTIC
MASSACHUSETTS GENERAL HOSPITAL
$166,000THERAPEUTIC
UNIVERSITY OF CALIFORNIA (UCLA)
$155,192THERAPEUTIC
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
$37,500THERAPEUTIC
AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA
$400,000THERAPEUTIC
CHILDRENS HOSPITAL OF PHILADELPHIA
$334,000THERAPEUTIC
UNIVERSITY OF ALABAMA AT BIRMINGHAM
$250,000THERAPEUTIC
MASSACHUSETTS GENERAL HOSPITAL
$167,000THERAPEUTIC
UNIVERSITY OF COLORADO
$89,850THERAPEUTIC
UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER
$75,000THERAPEUTIC
UNIVERSITY OF FLORIDA
$625,000THERAPEUTIC
UNIVERSITY OF ALABAMA AT BIRMINGHAM
$500,000THERAPEUTIC
MASSACHUSETTS GENERAL HOSPITAL
$269,000THERAPEUTIC
AUGUSTA UNIVERSITY MEDICAL COLLEGE OF GEORGIA
$100,000THERAPEUTIC
UNIVERSITY COLORADO
$88,900THERAPEUTIC
NATIONAL INSTITUTES OF HEALTH
$65,000THERAPEUTIC
UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT HOUSTON
$50,000THERAPEUTIC
MEMORIAL SLOAN KETTERING CANCER CENTER
$37,500THERAPEUTIC