To fund less toxic therapies for children with cancer so they can have a better quality of life during treatment, to fund and expand access to potentially life‑saving clinical trials, to support families emotionally and financially, and to raise awareness through advocacy and their Emmy‑award winning documentary campaign The Truth 365.
Arms Wide Open Childhood Cancer Foundation centers its giving on less toxic therapies for children with cancer, and its recent grants show that mission reaching hospitals, research centers, and collaborative research funds across the country. One of the clearest signals is its support for large research awards tied to pediatric oncology, including $397,500 to Tough2gether in Manhattan, Kansas, for cancer research and $155,000 to Memorial Sloan Kettering Cancer Center in New York for an anti-NB vaccine trial. The foundation also backs named donor funds that direct money into disease-specific work, such as the Awoccf Neuroblastoma Initiatives Fund in Marlboro, New Jersey. Beyond research, it supports the broader childhood-cancer ecosystem with grants that link research institutions, advocacy groups, and clinical programs. Its mix of awards includes both broad collaborative research support and targeted funding for neuroblastoma, DIPG/DMG, immunotherapy, and other pediatric cancer projects. That pattern suggests a funder focused on moving research toward therapies that may reduce treatment toxicity while also strengthening the infrastructure around children and families affected by cancer.
A major theme in the portfolio is pediatric cancer research aimed at safer treatment. The foundation gave $99,996 to Stanford University for pediatric cancer immunotherapy research and $60,185 to the Regents of the University of Michigan for the same purpose, showing support for translational work in major academic centers. Neuroblastoma appears as a specific priority through the $155,000 grant to Memorial Sloan Kettering Cancer Center for an anti-NB vaccine trial. The foundation also backs collaborative pediatric cancer research through a $128,628 award to Rally Foundation under its Collaborative Pediatric Cancer Research Awards Program. Another research angle is therapeutic development through grants such as $50,000 to Children's Cancer Therapy Development Institute and $49,500 to Sonalasense Inc.
Typical grants cluster around a median of $40,000, with a lower quartile of $10,185 and an upper quartile of $125,000. The recent record includes a wide spread, from $10,185 awards to six-figure research grants. Several recipients appear more than once across the recent-grants list, including Tough2gether, Rally Foundation, Sonalasense Inc, Children's Hospital of Philadelphia Foundation, Solving Kids Cancer, The Chadtough Foundation, and Awoccf Neuroblastoma Initiatives Fund. The foundation uses both its own research-grant programs and named donor funds, and it accepts unsolicited applications for some programs, including general research grants through Proposal Central and monthly family support grants by form and email.
$273K
$409K
$1.2M
$1.1M
Most grants fall between $10K and $125K, with a median of $40K.
25th Percentile
$10K
Median
$40K
75th Percentile
$125K
About 5% of grants go to recipients in CA.
DENA SHERWOOD
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Grantmaking is national, and every recent grant in the dataset went to a U.S. recipient. Georgia appears most often by recipient count, with awards to Atlanta-based Children's Healthcare of Atlanta and Rally Foundation. New York City recipients include Memorial Sloan Kettering Cancer Center and Solving Kids Cancer, while Philadelphia appears through Children's Hospital of Philadelphia Foundation. Other recent grants reached Manhattan, Kansas; San Francisco; Stanford, California; Seattle; Chicago; and Denver. New Jersey recipients account for 5% of grants, including the Marlboro-based Awoccf Neuroblastoma Initiatives Fund.
Arms Wide Open Childhood Cancer Foundation focuses on less toxic therapies for children with cancer. Its program descriptions also point to pediatric cancer research, clinical trials, survivorship, palliative care, family support, and disease-specific work in neuroblastoma, DIPG/DMG, sarcomas, and leukemia.
The distribution centers on a median grant size of $40,000, with p25 at $10,185 and p75 at $125,000. Recent awards include both smaller grants at the lower end and six-figure research commitments.
Yes, for some programs. The foundation accepts unsolicited family support applications by form and email, and it also accepts unsolicited research applications through Proposal Central for its annual childhood cancer research process.
Its recent grants go to pediatric oncology research institutions, cancer centers, and collaborative research funds. Examples in the data include university-affiliated medical centers, children’s hospitals, and named donor funds that direct money to pediatric cancer research and specific initiatives.
Grant recipients are U.S.-based across the board, and Georgia shows up most often by recipient count. Recent Georgia recipients include Atlanta organizations, while other grants reached New York, California, Kansas, Pennsylvania, Colorado, Washington, Illinois, and New Jersey.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| RALLY FOUNDATION | ATLANTA, GA | $128,773 | 2025 | TO FURTHER CANCER RESEARCH |
| CHILDREN'S CANCER THERAPY DEVELOPMENT INSTITUTE | HILLSBORO, OR | $50,000 | 2025 | TO FURTHER CANCER RESEARCH |
| ONCOHEROES | HOLLISTON, MA | $45,000 | 2025 | TO FURTHER CANCER RESEARCH |
| TOUGH2GETHER | MANHATTAN, KS | $28,942 | 2025 | TO FURTHER CANCER RESEARCH |
| CHILDREN'S HEALTHCARE OF ATLANTA | ATLANTA, GA | $10,000 | 2025 | TO FURTHER CANCER RESEARCH |
| THE EVAN FOUNDATION | GERMANTOWN, MD | $10,000 | 2025 | TO FURTHER CANCER RESEARCH |
| TOUGH2GETHER | MANHATTAN, KS | $397,500 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| TOUGH2GETHER | MANHATTAN, KS | $397,500 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| RALLY FOUNDATION | ATLANTA, GA | $128,628 | 2024 | TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM |
| RALLY FOUNDATION | ATLANTA, GA | $128,628 | 2024 | TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM |
| AWOCCF NEUROBLASTOMA INITIATIVES FUND | MARLBORO, NJ | $125,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| AWOCCF NEUROBLASTOMA INITIATIVES FUND | MARLBORO, NJ | $125,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SONALASENSE INC | OAKLAND, CA | $49,500 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SONALASENSE INC | OAKLAND, CA | $49,500 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION | PHILADELPHIA, PA | $40,000 | 2024 | RESEARCH FUNDING |
| CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION | PHILADELPHIA, PA | $40,000 | 2024 | RESEARCH FUNDING |
| THE CHADTOUGH FOUNDATION | SALINE, MI | $25,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| THE CHADTOUGH FOUNDATION | SALINE, MI | $25,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SOLVING KIDS CANCER | NEW YORK, NY | $20,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SOLVING KIDS CANCER | NEW YORK, NY | $20,000 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| STAMFORD UNIVERSITY | STANFORD, CA | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| STAMFORD UNIVERSITY | STANFORD, CA | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| LURRE'S CHILDRENS HOSPITAL | CHICAGO, IL | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SEATTLE CHILDREN'S FOUNDATION | SEATTLE, WA | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| LURRE'S CHILDRENS HOSPITAL | CHICAGO, IL | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| SEATTLE CHILDREN'S FOUNDATION | SEATTLE, WA | $10,185 | 2024 | TO ASSIST WITH CANCER RESEARCH |
| UCSF PEDIATRIC NUERO ONCOLOGY | SAN FRANCISCO, CA | $170,236 | 2023 | TO ASSIST WITH CANCER RESEARCH |
| MEMORIAL SLOAN KETTERING CANCER CENTER | NEW YORK, NY | $155,000 | 2023 | FUNDIING ANTI-NB VACCINE TRIAL |
| RALLY FOUNDATION-COLLABORATIVE PEDIATRIC CANCEL RESEARCH | ATLANTA, GA | $125,000 | 2023 | TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM |
| UNIVERSITY OF COLORADO | DENVER, CO | $110,178 | 2023 | TO ASSIST WITH CANCER RESEARCH |
| STANFORD UNIVERSITY | STANFORD, CA | $99,996 | 2023 | PEDIATRIC CANCER IMMUNOTHERAPY RESEARCH |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $60,185 | 2023 | PEDIATRIC CANCER IMMUNOTHERAPY RESEARCHPEDIATRIC CANCER IMMUNOTHERAPY RESEARCHPEDIATRIC CANCER IMMUNOTHERAPY RESEARCH |
| FOCUSED ULTRASOUND FOUNDATION | CHARLOTTESVILLE, VA | $25,000 | 2023 | TO ASSIST WIHT CANCER RESEARCH |
| CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION | PHILADELPHIA, PA | $24,000 | 2023 | RESEARCH FUNDING |
| CHILDREN'S HEALTHCARE OF ATLANTA | ATLANTA, GA | $10,185 | 2023 | RESEARCH FUNDING |
| SEATTLE CHILDREN'S FOUNDATION | SEATTLE, WA | $10,000 | 2023 | TO ASSIST WITH CANCER RESEARCH |
| GREATER MANHATTEN COMMUNITY | MANHATTAN, KS | $10,000 | 2023 | PEDIATRIC CANCER IMMUNOTHERAPY RESEARCH |
ONCOHEROES
$45,000TO FURTHER CANCER RESEARCH
TOUGH2GETHER
$28,942TO FURTHER CANCER RESEARCH
CHILDREN'S HEALTHCARE OF ATLANTA
$10,000TO FURTHER CANCER RESEARCH
THE EVAN FOUNDATION
$10,000TO FURTHER CANCER RESEARCH
TOUGH2GETHER
$397,500TO ASSIST WITH CANCER RESEARCH
TOUGH2GETHER
$397,500TO ASSIST WITH CANCER RESEARCH
TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM
TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM
AWOCCF NEUROBLASTOMA INITIATIVES FUND
$125,000TO ASSIST WITH CANCER RESEARCH
AWOCCF NEUROBLASTOMA INITIATIVES FUND
$125,000TO ASSIST WITH CANCER RESEARCH
SONALASENSE INC
$49,500TO ASSIST WITH CANCER RESEARCH
SONALASENSE INC
$49,500TO ASSIST WITH CANCER RESEARCH
CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION
$40,000RESEARCH FUNDING
CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION
$40,000RESEARCH FUNDING
THE CHADTOUGH FOUNDATION
$25,000TO ASSIST WITH CANCER RESEARCH
THE CHADTOUGH FOUNDATION
$25,000TO ASSIST WITH CANCER RESEARCH
SOLVING KIDS CANCER
$20,000TO ASSIST WITH CANCER RESEARCH
SOLVING KIDS CANCER
$20,000TO ASSIST WITH CANCER RESEARCH
STAMFORD UNIVERSITY
$10,185TO ASSIST WITH CANCER RESEARCH
STAMFORD UNIVERSITY
$10,185TO ASSIST WITH CANCER RESEARCH
LURRE'S CHILDRENS HOSPITAL
$10,185TO ASSIST WITH CANCER RESEARCH
LURRE'S CHILDRENS HOSPITAL
$10,185TO ASSIST WITH CANCER RESEARCH
UCSF PEDIATRIC NUERO ONCOLOGY
$170,236TO ASSIST WITH CANCER RESEARCH
MEMORIAL SLOAN KETTERING CANCER CENTER
$155,000FUNDIING ANTI-NB VACCINE TRIAL
TO ASSIST WITH CANCER RESEARCH- COLLABORATIVE PEADIATRIC CANCER RESEARCH AWARDS PROGRAM
UNIVERSITY OF COLORADO
$110,178TO ASSIST WITH CANCER RESEARCH
REGENTS OF THE UNIVERSITY OF MICHIGAN
$60,185PEDIATRIC CANCER IMMUNOTHERAPY RESEARCHPEDIATRIC CANCER IMMUNOTHERAPY RESEARCHPEDIATRIC CANCER IMMUNOTHERAPY RESEARCH
CHILDREN'S HOSPITAL OF PHILADELPHIA FOUNDATION
$24,000RESEARCH FUNDING
CHILDREN'S HEALTHCARE OF ATLANTA
$10,185RESEARCH FUNDING
GREATER MANHATTEN COMMUNITY
$10,000PEDIATRIC CANCER IMMUNOTHERAPY RESEARCH