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    3. American Cancer Society
    American Cancer Society logo

    American Cancer Society

    ActiveDiseases & Disorders
    Atlanta, GAWebsite8002272345

    About American Cancer Society

    To eliminate cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer through research, education, advocacy, and service.

    Focus Areas

    Cancer researchPrevention & risk factors (tobacco, diet, physical activity)Screening and early detectionPatient support services (rides, lodging, helpline)Community fundraising (Relay For Life, Making Strides)

    Who They Fund

    external researchers/institutions (extramural investigators)patients (recipient-facing support services)research programs/teams (program-level support)

    Funding Style

    extramural research grantsprogram support

    About American Cancer Society

    American Cancer Society Inc pairs large-scale program support with a long pipeline of research and training grants. In the recent grants list, the biggest awards go to the American Cancer Society Cancer Action Network in Washington, DC, including $38,070,794 in 2025 and $36,352,310 in 2023, showing that advocacy and public-policy work sits alongside its research funding. The foundation also backs major academic medical centers and universities through extramural research and support/research awards, including $9,837,685 to Massachusetts General Hospital in Somerville, MA and $6,670,500 to Icahn School of Medicine at Mt Sinai in New York, NY. Its active programs point to a broad research agenda: investigator-initiated cancer studies, clinician-scientist development, post-baccalaureate training, institutional seed funding, and staged translational grants. The organization’s stated purpose is to eliminate cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering through research, education, advocacy, and service.

    What American Cancer Society Funds

    Cancer research is the clearest throughline. American Cancer Society Inc gave $6,719,500 to The University of Texas Health Science Center at San Antonio for extramural research in 2023, and $5,618,158 to Yale University for extramural research in 2024. It also funds independent investigators through Research Scholar Grants and institutional seed support through Institutional Research Grants. Training is another visible area: the ACS Center for Innovation in Cancer Research Training supports two-year post-baccalaureate cancer research training programs for participants preparing for doctoral study. Translational work appears in Mission Boost Grants, which move patient-focused research toward clinical impact. Patient-facing support is part of the portfolio as well, reflected in the foundation’s stated focus on rides, lodging, and helpline services.

    How American Cancer Society Gives

    Typical grant size clusters at $10,000 at the 25th percentile, $20,000 at the median, and $60,000 at the 75th percentile. The recent record shows both very large program awards and a broad base of research grants, with awards recurring across years to the same institutions and entities, such as Washington University, Yale University, and Dana Farber Cancer Institute. American Cancer Society Inc is classified as a regular funder and operates as a national grantmaker. Its active opportunities are described as unsolicited and application-based, including research grants, clinician-scientist development, institutional grants, and mission-oriented funding mechanisms.

    Financial Snapshot

    Annual Giving

    $574M

    Total Assets

    $1.7B

    Total Revenue

    $724.2M

    Total Expenses

    $791.9M

    Typical Grant Size

    Most grants fall between $10K and $60K, with a median of $20K.

    25th Percentile

    $10K

    Median

    $20K

    75th Percentile

    $60K

    Geographic Reach

    National53 states funded

    About 3% of grants go to recipients in NY.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

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    Privacy PolicyTerms of ServiceSystem Status
    EIN: 13-1788491
    3 filings on record
    research support (operational/technical)
    patient support funding
    project-based/grantmaking

    Topics

    extramural biomedical/clinical researchsupport for research projects and investigatorspatient support services associated with research/clinical careresearch infrastructure and programmatic capacitysupport/research hybrids (program + research funding)

    Where American Cancer Society Makes Grants

    Grantmaking is national, and all recent grants shown go to US recipients. The highest concentration by state is New York, while Georgia accounts for 3% of grants. In the recent list, Washington, DC appears repeatedly through program support to the American Cancer Society Cancer Action Network, and New York City appears through Icahn School of Medicine at Mt Sinai and Columbia University. Other frequent recipient locations include Boston, New Haven, St Louis, and Philadelphia, indicating a strong mix of major academic medical centers and policy-focused grantees.

    Frequently Asked Questions About American Cancer Society

    What kinds of work does American Cancer Society Inc fund?

    The foundation funds cancer research, prevention and risk-factor work, screening and early detection, patient support services, and community fundraising programs. Its active grant programs include investigator research, clinician-scientist development, post-baccalaureate training, institutional seed grants, and translational research support.

    How large are its typical grants?

    The grant-size distribution centers at $10,000 at the 25th percentile, $20,000 at the median, and $60,000 at the 75th percentile. The recent grants list also includes much larger awards for program support and research, showing a wide spread across grant types.

    Does it fund organizations outside the United States?

    The recipient country distribution shown is entirely US-based: 2,059 grants, or 100.0%, go to US recipients. The active grant programs listed are also scoped to the United States.

    Can organizations apply directly for funding?

    Yes. The active programs include multiple unsolicited opportunities, such as American Cancer Society — Research Grants, Clinician Scientist Development Grant, Discovery Boost Grants, Research Scholar Grants, Institutional Research Grants, and Mission Boost Grants.

    Which types of recipients appear most often in the recent grants list?

    The recent grants list is dominated by academic medical centers, universities, and research institutions such as Massachusetts General Hospital, Yale University, Washington University, Columbia University, and Dana Farber Cancer Institute, alongside program support to the American Cancer Society Cancer Action Network in Washington, DC.

    DR KAREN E KNUDSEN PHD

    Accepts unsolicited proposals
    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    American Cancer Society Cancer Action NetworkWashington, DC$38,070,7942025Program Support
    Massachusetts General HospitalSomerville, MA$9,837,6852025Support/Research
    Icahn School Of Medicine At Mt SinaiNew York, NY$6,670,5002025Support/Research
    Oregon Health & Science UniversityPortland, OR$4,598,5542025Extramural Research
    Yale UniversityNew Haven, CT$4,516,7572025Extramural Research
    Washington UniversitySt Louis, MO$4,213,5002025Extramural Research
    University of Oklahoma Health Sciences CenterOklahoma City, OK$4,125,0002025Support/Research
    Brigham And Womens HospitalBoston, MA$3,681,7432025Extramural Research
    Ut Southwestern Medical CenterDallas, TX$3,452,0002025Extramural Research
    University of Alabama at BirminghamBirmingham, AL$3,204,5002025Support/Research
    Dana Farber Cancer InstituteBoston, MA$3,193,0002025Support/Research
    Medical University Of South CarolinaCharleston, SC$3,171,0002025Support/Research
    Ohio State UniversityColumbus, OH$3,015,4112025Extramural Research
    U Of Tx Md Anderson Cancer CtrHouston, TX$2,952,2342025Extramural Research
    Trustees of the University of PennPhiladelphia, PA$2,611,5002025Support/Research
    Duke University Health System IncDurham, NC$2,520,5002025Support/Research
    University Of Utah Research FoundationSalt Lake City, UT$2,516,4522025Extramural Research
    University of Texas Health Science CenterSan Antonio, TX$2,389,5002025Support/Research
    Regents Of The University Of California at IrvineIrvine, CA$2,332,0002025Extramural Research
    The Cleveland Clinic FoundationCleveland, OH$1,987,5002025Support/Research
    Board Of Trustees Of Leland Stanford Junior UniversityRedwood City, CA$1,963,5002025Support/Research
    Fred Hutchinson Cancer CenterSeattle, WA$1,926,0002025Extramural Research
    Weill Med College Of Cornell UNew York, NY$1,831,0002025Extramural Research
    Univ Of Nebraska Medical CenterOmaha, NE$1,824,0002025Extramural Research
    University of California San FranciscoSan Francisco, CA$1,781,2502025Support/Research
    President and Fellows Of Harvard CollegeBoston, MA$1,760,0002025Extramural Research
    University Of ChicagoChicago, IL$1,619,0002025Support/Research
    Sloan - Kettering Institute ForNew York, NY$1,604,0002025Extramural Research
    Georgetown UniversityWashington, DC$1,514,5002025Extramural Research
    Patient Advocate FoundationHampton, VA$1,470,0002025Patient Support
    H Lee Moffitt Cancer Center And Research Institute IncTampa, FL$1,457,0002025Extramural Research
    Regents Of The Univ Of MinnMinneapolis, MN$1,393,0002025Extramural Research
    Institute for Cancer ResearchPhiladelphia, PA$1,381,0002025Extramural Research
    University Of ArizonaTucson, AZ$1,347,5002025Extramural Research
    Univ Of Maryland BaltimoreBaltimore, MD$1,317,0002025Extramural Research
    Columbia UniversityNew York, NY$1,313,5002025Extramural Research
    Trustees Of Boston Univ BumcBoston, MA$1,286,2002025Extramural Research
    Sanford Burnham Prebys Medical Discovery InstituteLa Jolla, CA$1,231,0622025Extramural Research
    Baylor College Of Medicine HealthcareHouston, TX$1,108,5002025Extramural Research
    Board Of Regents On The UnivMadison, WI$1,078,0002025Extramural Research
    University of Kentucky Research FoundationCleveland, OH$1,073,0002025Support/Research
    Wake Forest University Health SciencesWinston Salem, NC$1,059,0362025Support/Research
    University Of MiamiCoral Gables, FL$1,040,0002025Support/Research
    American College Of SurgeonsChicago, IL$1,021,5002025Support/Research
    Trustees Of Dartmouth CollegeHanover, NH$1,020,0002025Extramural Research
    University Of PittsburghPittsburgh, PA$1,019,0792025Extramural Research
    Beckman Research Institute of the City of HopeDuarte, CA$1,006,9562025Support/Research
    University Of IllinoisUrbana, IL$987,2502025Support/Research
    University Of Illinois ChicagoChicago, IL$961,4622025Extramural Research
    Purdue UniversityChicago, IL$960,0002025Extramural Research

    American Cancer Society Cancer Action Network

    $38,070,794
    Washington, DC2025

    Program Support

    Massachusetts General Hospital

    $9,837,685
    Somerville, MA2025

    Support/Research

    Icahn School Of Medicine At Mt Sinai

    $6,670,500
    New York, NY2025

    Support/Research

    Oregon Health & Science University

    $4,598,554
    Portland, OR2025

    Extramural Research

    Yale University

    $4,516,757
    New Haven, CT2025

    Extramural Research

    Washington University

    $4,213,500
    St Louis, MO2025

    Extramural Research

    University of Oklahoma Health Sciences Center

    $4,125,000
    Oklahoma City, OK2025

    Support/Research

    Brigham And Womens Hospital

    $3,681,743
    Boston, MA2025

    Extramural Research

    Ut Southwestern Medical Center

    $3,452,000
    Dallas, TX2025

    Extramural Research

    University of Alabama at Birmingham

    $3,204,500
    Birmingham, AL2025

    Support/Research

    Dana Farber Cancer Institute

    $3,193,000
    Boston, MA2025

    Support/Research

    Medical University Of South Carolina

    $3,171,000
    Charleston, SC2025

    Support/Research

    Ohio State University

    $3,015,411
    Columbus, OH2025

    Extramural Research

    U Of Tx Md Anderson Cancer Ctr

    $2,952,234
    Houston, TX2025

    Extramural Research

    Trustees of the University of Penn

    $2,611,500
    Philadelphia, PA2025

    Support/Research

    Duke University Health System Inc

    $2,520,500
    Durham, NC2025

    Support/Research

    University Of Utah Research Foundation

    $2,516,452
    Salt Lake City, UT2025

    Extramural Research

    University of Texas Health Science Center

    $2,389,500
    San Antonio, TX2025

    Support/Research

    Regents Of The University Of California at Irvine

    $2,332,000
    Irvine, CA2025

    Extramural Research

    The Cleveland Clinic Foundation

    $1,987,500
    Cleveland, OH2025

    Support/Research

    Board Of Trustees Of Leland Stanford Junior University

    $1,963,500
    Redwood City, CA2025

    Support/Research

    Fred Hutchinson Cancer Center

    $1,926,000
    Seattle, WA2025

    Extramural Research

    Weill Med College Of Cornell U

    $1,831,000
    New York, NY2025

    Extramural Research

    Univ Of Nebraska Medical Center

    $1,824,000
    Omaha, NE2025

    Extramural Research

    University of California San Francisco

    $1,781,250
    San Francisco, CA2025

    Support/Research

    President and Fellows Of Harvard College

    $1,760,000
    Boston, MA2025

    Extramural Research

    University Of Chicago

    $1,619,000
    Chicago, IL2025

    Support/Research

    Sloan - Kettering Institute For

    $1,604,000
    New York, NY2025

    Extramural Research

    Georgetown University

    $1,514,500
    Washington, DC2025

    Extramural Research

    Patient Advocate Foundation

    $1,470,000
    Hampton, VA2025

    Patient Support

    H Lee Moffitt Cancer Center And Research Institute Inc

    $1,457,000
    Tampa, FL2025

    Extramural Research

    Regents Of The Univ Of Minn

    $1,393,000
    Minneapolis, MN2025

    Extramural Research

    Institute for Cancer Research

    $1,381,000
    Philadelphia, PA2025

    Extramural Research

    University Of Arizona

    $1,347,500
    Tucson, AZ2025

    Extramural Research

    Univ Of Maryland Baltimore

    $1,317,000
    Baltimore, MD2025

    Extramural Research

    Columbia University

    $1,313,500
    New York, NY2025

    Extramural Research

    Trustees Of Boston Univ Bumc

    $1,286,200
    Boston, MA2025

    Extramural Research

    Sanford Burnham Prebys Medical Discovery Institute

    $1,231,062
    La Jolla, CA2025

    Extramural Research

    Baylor College Of Medicine Healthcare

    $1,108,500
    Houston, TX2025

    Extramural Research

    Board Of Regents On The Univ

    $1,078,000
    Madison, WI2025

    Extramural Research

    University of Kentucky Research Foundation

    $1,073,000
    Cleveland, OH2025

    Support/Research

    Wake Forest University Health Sciences

    $1,059,036
    Winston Salem, NC2025

    Support/Research

    University Of Miami

    $1,040,000
    Coral Gables, FL2025

    Support/Research

    American College Of Surgeons

    $1,021,500
    Chicago, IL2025

    Support/Research

    Trustees Of Dartmouth College

    $1,020,000
    Hanover, NH2025

    Extramural Research

    University Of Pittsburgh

    $1,019,079
    Pittsburgh, PA2025

    Extramural Research

    Beckman Research Institute of the City of Hope

    $1,006,956
    Duarte, CA2025

    Support/Research

    University Of Illinois

    $987,250
    Urbana, IL2025

    Support/Research

    University Of Illinois Chicago

    $961,462
    Chicago, IL2025

    Extramural Research

    Purdue University

    $960,000
    Chicago, IL2025

    Extramural Research