About Alfred E Mann Charities
Alfred E Mann Charities directs large, targeted gifts to major Southern California medical centers, emphasizing support for clinical care, biomedical research, and institutional capacity. Grants are sizable and institution-focused—aimed at established hospitals and research centers rather than small nonprofits or broad cause portfolios. The foundation shows an interest in advancing health care delivery and medical science through concentrated institutional support.
Focus Areas
Capital and general support for major academic medical centers in Southern CaliforniaCancer research and treatment programs (e.g., City of Hope)Translational biomedical research and medical technology/innovation fundingHospital infrastructure and program support at large health systems (e.g., Cedars‑Sinai)
Who They Fund
nonprofit organizations (unspecified)general public/communities (unspecified)
Giving Approach
Highly concentrated giving: very few, very large grants to elite medical institutions; evidence of repeat funding to the same grantee (City of Hope).
About Alfred E Mann Charities
A 2025 $5,000,000 grant to Cedars-Sinai Medical Center captures the foundation’s pattern: Alfred E Mann Charities Inc directs substantial charitable support to established institutions, especially in health care and biomedical research. The recent grants list shows repeated seven-figure awards to major Southern California hospitals, research foundations, and university-linked medical programs, alongside gifts to a small number of arts and community organizations. This is a funder that works through concentrated institutional grants rather than a broad roster of small awards. Health-related support appears repeatedly across the portfolio, with gifts to Cedars-Sinai, City of Hope, UCLA Foundation, Children’s Hospital Los Angeles, and USC-linked medical programs. The foundation also backs organizations outside medicine when they fit its broader charitable priorities, including cultural institutions and community-serving nonprofits in Los Angeles. Its grantmaking is regional, but the recipient list extends beyond one metro area and includes a small amount of international giving. The scale is meaningful even by institutional-funder standards, with multiple grants in the $1 million to $5 million range and recurring support for the same large organizations over several years.
What Alfred E Mann Charities Funds
Biomedical research and medical innovation are central to Alfred E Mann Charities Inc’s recent giving. In 2025, it awarded $1,500,000 to the UCLA Foundation and $250,000 to USC Neurorevascularization Center, both tied to health and science priorities. Children’s health is another visible theme. The foundation gave $1,000,000 to Children’s Hospital - Los Angeles in 2025 and another $1,000,000 to Children’s Hospital Los Angeles in 2023, showing repeated support for pediatric care institutions. The portfolio also includes cancer and hospital-based care. City of Hope received $3,025,000 in 2024 and $2,025,000 in 2025, while Cedars-Sinai Medical Center received $1,000,000 in 2024 and $5,000,000 in 2025. Beyond health, the foundation funded arts and culture organizations, including $375,000 to the Simon Wiesenthal Center in 2024 and 2025, and $250,000 and $250,000 to Los Angeles Opera Company in 2024 and 2025.
How Alfred E Mann Charities Gives
Typical grants are concentrated in the middle of the distribution, with a p25 of $7,800, a median of $10,000, and a p75 of $50,000. The recent-grants list, however, shows a second layer of much larger institution-level gifts, including multiple seven-figure awards. Grantmaking is clearly recurring rather than one-off. Several recipients appear in multiple years, including Cedars-Sinai Medical Center, City of Hope, the Lucile Packard Foundation, UCLA Foundation, Children’s Hospital Los Angeles, American Friends of Magen David Adom, Karsh Center, Alliance Foundation, Simon Wiesenthal Center, Los Angeles Opera Company, and USC Neurorevascularization Center. Alfred E Mann Charities Inc is a regular funder, not a DAF and not an individual-giving funder. Grants are made through charitable support rather than program-related investments, and the listed programs show strategic, institution-based funding.
Financial Snapshot
Annual Giving
$44.8M
Total Assets
$331.8M
Total Revenue
$33.7M
Total Expenses
$47.2M
Typical Grant Size
Most grants fall between $8K and $50K, with a median of $10K.
25th Percentile
$8K
Median
$10K
75th Percentile
$50K
Geographic Reach
Regional15 states funded
Funding intensity
LowHigh
Headquarters
Funding intensity
LowHigh
Where Alfred E Mann Charities Funds
Top 2 recipient countries by grant volume for Alfred E Mann Charities.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 268 | $35.3M | 99.6% |
| 2 | Israel |
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