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    5. Kaleidoscope of Hope Foundation
    Logo de Kaleidoscope of Hope Foundation

    Kaleidoscope of Hope Foundation

    ActivoMedical Research
    MADISON, NJSitio web9736440500EIN: 22-3744037

    About Kaleidoscope of Hope Foundation

    The mission of the Kaleidoscope of Hope Ovarian Cancer Foundation is to raise funds for ovarian cancer research and increase awareness of the symptoms of this disease.

    Focus Areas

    ovarian cancer researchearly detectiontreatment researchcommunity grants for patients and familiesawareness and education

    Who They Fund

    patients with high‑grade serous ovarian cancer (HGSOC)patients with clear cell ovarian cancer (CCOC)patients undergoing chemotherapy / surgical resection whose tissue and blood are available for biomarker studies

    Funding Style

    project-specific research grantspreclinical/animal study support

    About Kaleidoscope of Hope Foundation

    Kaleidoscope of Hope Foundation Inc centers its giving on ovarian cancer research, with grants aimed at early detection, treatment research, and awareness. The foundation’s recent awards show a strong project-specific research pattern: a $50,000 grant to Women & Infant Hospital of Rhode Island supported work on spatially resolved immune responses to chemotherapy in high-grade serous ovarian cancer, while another $50,000 award to the Trustees of the University of Pennsylvania backed a p53-stabilizing treatment combination in TP53 wild type ovarian cancer. A separate $50,000 grant to Temple University supported study of CARM1 in cytokine-mediated antitumor response. The portfolio also reaches translational and biomarker work, including liquid biopsy research at University of Texas MD Anderson Cancer Center and a taurine-based ovarian cancer project at Stevens Institute of Technology. Alongside institutional research, the foundation also funds community support for people affected by ovarian cancer and their families. Its mission statement emphasizes both research funding and increasing awareness of symptoms, and the grant record reflects that dual emphasis through awards to investigators, medical centers, and patient-facing support.

    What Kaleidoscope of Hope Foundation Funds

    The foundation supports several distinct ovarian cancer research themes. In biomarker and translational work, it gave $25,000 to University of Texas MD Anderson Cancer Center for liquid biopsy research using extracellular vesicles to identify molecular predictors of disease patterns from matched tissue and blood. In treatment discovery, it awarded $50,000 to the Trustees of the University of Pennsylvania for an investigation of a p53-stabilizing targeted treatment combination in TP53 wild type ovarian cancer. It also funded $25,000 to Stevens Institute of Technology for a taurine-based study, described as testing whether nutritional taurine suppresses ovarian cancer. Another 2023 award of $25,000 to the Trustees of the University of Pennsylvania focused on clear cell ovarian cancer and combination DNA damage inhibitor strategies. The research topics point to a mix of early detection, experimental therapeutics, and subtype-specific biology.

    How Kaleidoscope of Hope Foundation Gives

    Typical grants cluster around $25,000 to $50,000, with a median of $25,000 and a 75th percentile of $50,000. The recent record includes repeated support for some recipients: University of Texas MD Anderson Cancer Center and the Trustees of the University of Pennsylvania each appear in more than one year, suggesting multi-year relationships rather than one-off awards. The foundation’s grant programs are research-oriented and include annual calls for proposals, with one program explicitly accepting unsolicited applications. It does not fund individuals directly through this research line, and the listed structure points to project-specific research support rather than unrestricted operating grants.

    Financial Snapshot

    Annual Giving

    $150K

    Total Assets

    $624K

    Total Revenue

    $181K

    Total Expenses

    $171K

    Typical Grant Size

    Most grants fall between $25K and $50K, with a median of $25K.

    25th Percentile

    $25K

    Median

    $25K

    75th Percentile

    $50K

    Geographic Reach

    Regional5 states funded

    About 14% of grants go to recipients in TX.

    Intensidad de financiamiento
    Baja
    Alta
    Sede

    Leadership

    EMILY DENAPOLI CO-PRES

    Accepts unsolicited proposals

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    translational/clinical validation funding
    experimental therapeutics & biomarker development

    Topics

    high‑grade serous ovarian cancer biology and treatmentclear cell ovarian cancer therapeutic discoverytumor immunology and cytokine‑mediated antitumor responsesp53‑stabilizing targeted therapiesliquid biopsy/extracellular vesicle biomarker discovery for chemo responseimmune checkpoint markers longitudinal monitoring (LAG3, PD‑1, ICOS, OX40)combination DNA damage inhibitors + BET inhibitor strategiesnutritional compound (taurine) as anticancer agentCRISPR screens for novel therapeutic targets

    Where Kaleidoscope of Hope Foundation Makes Grants

    Grantmaking is regional and remains U.S.-based in the recent record, with all listed recent grants going to U.S. recipients. Texas appears as the top state by grant count, driven in part by awards to Houston-based University of Texas MD Anderson Cancer Center. New Jersey also appears in the grant record through Stevens Institute of Technology in Hoboken, while Pennsylvania receives support through Philadelphia-based University of Pennsylvania and Temple University. Recent awards also reach Providence, Rhode Island, showing that the foundation’s research funding extends beyond its headquarters state.

    Frequently Asked Questions About Kaleidoscope of Hope Foundation

    What kinds of projects does Kaleidoscope of Hope Foundation Inc fund?

    Its grants focus on ovarian cancer research, early detection, treatment research, awareness and education, and community grants for patients and families. Recent awards include immune-response studies, p53-targeted treatment research, liquid biopsy biomarker work, and a taurine-based ovarian cancer project.

    Does the foundation support more than one research project over time?

    Yes. The recent grant record shows repeat awards to University of Texas MD Anderson Cancer Center in 2023 and 2024, and to the Trustees of the University of Pennsylvania in both years as well. That pattern suggests ongoing support for selected research programs.

    What is the typical grant size?

    Typical awards are $25,000, with a median of $25,000 and a 75th percentile of $50,000. Recent grants in the record include both $25,000 and $50,000 awards.

    Can applicants submit unsolicited proposals?

    Yes for at least one active program. The KOH Research Grant Program and the KOH Research Grants (2025 research RFP) both state that applicants submit research proposals, and the program listing says they accept unsolicited applications.

    What geographic area does the foundation fund most often?

    Its giving is regional and U.S.-based in the recent grant record. Texas is the top state by grant count, followed by New Jersey and Pennsylvania in the listed awards.

    Latest 990 Filing

    2024

    Source: IRS Form 990-PF, fiscal year 2024.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    TRUSTEES OF THE UNIVERISTY OF PENNSYLVANIAPHILADELPHIA, PA$50,0002024INVESTIGATION OF A NOVEL P53 STABILIZING TARGETED TREATMENT COMBINATION IN TP53 WILD TYPE OVARIAN CANCER.
    TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONNEW YORK, NY$50,0002024UNDERSTANDING THE ROLE OF CARM 1 IN REGULATION OF CYTOKINE-MEDIATED ANTITUMOR RESPONSE IN OVARIAN CANCER.
    UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTERHOUSTON, TX$25,0002024TO IDENTIFY LIQUID BIOPSY (EXTRACELLULAR VESICLES)BASED MOLECULAR PREDICTORS OF DISEASE PATTERNS FROM PATIENTS FROM MATCHED TISSUES AND BLOOD FROM PATIENTS WITH COMPLETE GROSS RESECTION AND PATIENTS WITH EXCELLENT AND POOR RESPONSE TO CHEMOTHERAPY, FOLLOWED BY CLINICAL VALLIDATION OF OUR FINDING IN PATIENTS WITH HIGHGRADE SEROUS OVARIAN CANCER.
    STEVENS INSTITUTE OF TECHNOLOGYHOBOKEN, NJ$25,0002024NUTRITIONAL SUPPLEMENT TAURINE SUPPRESSES OVARIAN CANCER.
    WOMEN & INFANT HOSPITAL OF RHODE ISLANDPROVIDENCE, RI$50,0002023DETERMINE SPATIALLY RESOLVED IMMUNE RESPONSES TO CHEMOTHERAPY IN HIGH GRADE SEROUS OVARIAN CANCER AND DETERMINE LEVELS OF SERUM LAG3, PD1, ICOS, AND OX40 THROUGHOUT THE COURSE OF CHEMOTHERAPY TREATMENT AND WHETHER THEY CORRELATE WITH PATIENT CLINICAL OUTCOMES.
    TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIAPHILADELPHIA, PA$25,0002023CLEAR CELL OVARIAN CANCER (CCOC) IS OFTEN RESISTANT TO STANDARD OF CARE CHEMOTHERAPY AND HAS LIMITED TREATMENT OPTIONS. DR. XU IS IDENTIFYING EFFECTIVE TREATMENT OPTIONS FOR CCOC BY COMBINATION OF DNA DAMARGE INHIBITORS AND BET INHIBITOR, AND ALSO DISCOVERING NEW TARGETS BY CRISPR SCREEN. WITH THE SUPPORT FROM KOH FOUNDATION, DR. XU WILL BE ABLE TO HAVE SUPPLIES AND ANIMALS TO CONTINUE THE STUDY AND IDENTIFY EFFECTIVE THERAPEUTICS FOR CCOC.
    UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTERHOUSTON, TX$25,0002023TO IDENTIFY LIQUID BIOPSY (EXTRACELLULAR VESICLES)BASED MOLECULAR PREDICTORS OF DISEASE PATTERNS FROM PATIENTS FROM MATCHED TISSUES AND BLOOD FROM PATIENTS WITH COMPLETE GROSS RESECTION AND PATIENTS WITH EXCELLENT AND POOR RESPONSE TO CHEMOTHERAPY, FOLLOWED BY CLINICAL VALLIDATION OF OUR FINDING IN PATIENTS WITH HIGHGRADE SEROUS OVARIAN CANCER.

    TRUSTEES OF THE UNIVERISTY OF PENNSYLVANIA

    $50,000
    PHILADELPHIA, PA2024

    INVESTIGATION OF A NOVEL P53 STABILIZING TARGETED TREATMENT COMBINATION IN TP53 WILD TYPE OVARIAN CANCER.

    TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

    $50,000
    NEW YORK, NY2024

    UNDERSTANDING THE ROLE OF CARM 1 IN REGULATION OF CYTOKINE-MEDIATED ANTITUMOR RESPONSE IN OVARIAN CANCER.

    UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER

    $25,000
    HOUSTON, TX2024

    TO IDENTIFY LIQUID BIOPSY (EXTRACELLULAR VESICLES)BASED MOLECULAR PREDICTORS OF DISEASE PATTERNS FROM PATIENTS FROM MATCHED TISSUES AND BLOOD FROM PATIENTS WITH COMPLETE GROSS RESECTION AND PATIENTS WITH EXCELLENT AND POOR RESPONSE TO CHEMOTHERAPY, FOLLOWED BY CLINICAL VALLIDATION OF OUR FINDING IN PATIENTS WITH HIGHGRADE SEROUS OVARIAN CANCER.

    STEVENS INSTITUTE OF TECHNOLOGY

    $25,000
    HOBOKEN, NJ2024

    NUTRITIONAL SUPPLEMENT TAURINE SUPPRESSES OVARIAN CANCER.

    WOMEN & INFANT HOSPITAL OF RHODE ISLAND

    $50,000
    PROVIDENCE, RI2023

    DETERMINE SPATIALLY RESOLVED IMMUNE RESPONSES TO CHEMOTHERAPY IN HIGH GRADE SEROUS OVARIAN CANCER AND DETERMINE LEVELS OF SERUM LAG3, PD1, ICOS, AND OX40 THROUGHOUT THE COURSE OF CHEMOTHERAPY TREATMENT AND WHETHER THEY CORRELATE WITH PATIENT CLINICAL OUTCOMES.

    Oportunidades de Subvenciones Abiertas

    Financiamiento actual y próximo de Kaleidoscope of Hope Foundation al que tu organización sin fines de lucro podría postularse.

    Abierta ahoraCierra el 15 nov 2026

    KOH Research Grant Program (annual research proposals)

    Ovarian cancer researchTranslational researchEarly detection and therapeutics

    ¿Quién puede postularse? Researchers conducting ovarian cancer research. Specific eligibility details are provided in the annual Grant Application materials (contact kohgrantinfo@kohnj.org for questions).

    Fecha límite: Full proposals for 2025 are due by Tuesday, October 28, 2025. Notification by end of March 2026. Reporting deadlines for awarded grants include: half-year progress report and one-page budget by November 15, 2026; final report (3 pages narrative and final budget) by May 15, 2027.

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    TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

    $25,000
    PHILADELPHIA, PA2023

    CLEAR CELL OVARIAN CANCER (CCOC) IS OFTEN RESISTANT TO STANDARD OF CARE CHEMOTHERAPY AND HAS LIMITED TREATMENT OPTIONS. DR. XU IS IDENTIFYING EFFECTIVE TREATMENT OPTIONS FOR CCOC BY COMBINATION OF DNA DAMARGE INHIBITORS AND BET INHIBITOR, AND ALSO DISCOVERING NEW TARGETS BY CRISPR SCREEN. WITH THE SUPPORT FROM KOH FOUNDATION, DR. XU WILL BE ABLE TO HAVE SUPPLIES AND ANIMALS TO CONTINUE THE STUDY AND IDENTIFY EFFECTIVE THERAPEUTICS FOR CCOC.

    UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER

    $25,000
    HOUSTON, TX2023

    TO IDENTIFY LIQUID BIOPSY (EXTRACELLULAR VESICLES)BASED MOLECULAR PREDICTORS OF DISEASE PATTERNS FROM PATIENTS FROM MATCHED TISSUES AND BLOOD FROM PATIENTS WITH COMPLETE GROSS RESECTION AND PATIENTS WITH EXCELLENT AND POOR RESPONSE TO CHEMOTHERAPY, FOLLOWED BY CLINICAL VALLIDATION OF OUR FINDING IN PATIENTS WITH HIGHGRADE SEROUS OVARIAN CANCER.