To provide compassionate medical care to people with cancer, diabetes and other life‑threatening illnesses and transforming the future of cancer care by unifying the branches of biomedical research, treatment and academia.
City of Hope’s recent giving is dominated by large operating support grants to its own research and care institutions in Duarte, including $48,529,658 to the Beckman Research Institute of the COH in 2023 and $41,830,802 to the City of Hope National Medical Center in 2025. That pattern fits the organization’s stated mission: providing compassionate medical care for people with cancer, diabetes, and other life-threatening illnesses while advancing cancer care through research, treatment, and academia. The foundation’s grantmaking is closely tied to its medical and research system rather than a broad external portfolio. Across the latest grants list, the same core institutions appear repeatedly, with Beckman Research Institute and City of Hope National Medical Center receiving the largest awards. The foundation also supports the Translational Genomics Research Institute, indicating attention to genomics-linked research within its broader biomedical agenda. Grants in the recent file are all operating support, and the recipient pool is entirely U.S.-based. City of Hope’s leadership is listed as Robert W Stone, President & CEO.
Cancer research and treatment is central to City of Hope’s grantmaking. The latest grants include $46,623,682 in 2025 to the Beckman Research Institute of the City Of Hope for operating support and $40,267,371 in 2024 to the City of Hope National Medical Center for operating support, both tied to the organization’s medical and research system. The foundation also supports translational genomics. In 2024, it gave $2,002,719 to The Translational Genomics Research Institute for operating support, followed by smaller awards in 2025 and 2023 to the same recipient. Its broader mission references diabetes care and research, HIV/AIDS care, stem cell biology and regenerative medicine, clinical trials and translational medicine, and precision medicine / genomics. The recent grants list does not show separate external awards in those areas, but it does show continuing support for biomedical infrastructure through operating grants.
The recent grant sizes are highly skewed: p25 is $320,938, the median is $26,214,443, and p75 is $42,857,122. That reflects a pattern of very large operating grants alongside a few much smaller awards. The grants list also shows repeated support for the same recipients across 2023, 2024, and 2025, especially within City of Hope’s own system. City of Hope makes program-related investments and gives locally; the latest grants are all operating support. The foundation’s portfolio is institution-centered rather than grant-by-grant project funding.
$88.9M
$4.2B
$413.3M
$221.7M
Most grants fall between $321K and $42.9M, with a median of $26.2M.
25th Percentile
$321K
Median
$26.2M
75th Percentile
$42.9M
About 82% of grants go to recipients in CA.
Robert W Stone
President & CEO
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City of Hope gives locally, and 82% of its grants go to recipients in California. The latest grants are all in the United States. Duarte is the main recipient city in the recent file, with multiple awards to Beckman Research Institute, City of Hope National Medical Center, and City of Hope Medical Foundation. Outside Duarte, the only named recipient city in the recent grants list is Phoenix, where The Translational Genomics Research Institute appears in both 2024 and 2025.
City of Hope funds its own medical and research institutions most heavily, including Beckman Research Institute of the City of Hope, City of Hope National Medical Center, and City of Hope Medical Foundation. The recent grants list also includes The Translational Genomics Research Institute, showing support for biomedical research infrastructure.
The grant-size distribution is large and uneven: p25 is $320,938, the median is $26,214,443, and p75 is $42,857,122. Recent awards range from $11,199 to $48,529,658.
Yes. Beckman Research Institute of the COH appears in 2023, 2024, and 2025; City of Hope National Medical Center appears in 2023, 2024, and 2025; and The Translational Genomics Research Institute appears in 2023, 2024, and 2025. The pattern is repeated operating support.
California is the top state by grant count, with 82% of grants going to recipients in the HQ state. Duarte is the main city in the recent grants list, and Phoenix also appears as a recipient city.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| Beckman Research Institute of the City Of Hope | DUARTE, CA | $46,623,682 | 2025 | OPERATING SUPPORT |
| City of Hope National Medical Center | DUARTE, CA | $41,830,802 | 2025 | OPERATING SUPPORT |
| The Translational Genomics Research Institute | PHOENIX, AZ | $408,198 | 2025 | OPERATING SUPPORT |
| Beckman Research Institute of the COH | Duarte, CA | $43,883,442 | 2024 | Operating Support |
| City of Hope National Medical Center | Duarte, CA | $40,267,371 | 2024 | Operating Support |
| The Translational Genomics Research Institute | Phoenix, CA | $2,002,719 | 2024 | Operating Support |
| City of Hope Medical Foundation | Duarte, CA | $11,199 | 2024 | Operating Support |
| Beckman Research Institute of the COH | Duarte, CA | $48,529,658 | 2023 | Operating Support |
| City of Hope National Medical Center | Duarte, CA | $26,214,443 | 2023 | Operating Support |
| The Translational Genomics Research Institute | Phoenix, AZ | $233,678 | 2023 | Operating Support |
| City of Hope Medical Foundation | Duarte, CA | $206,333 | 2023 | Operating Support |
Beckman Research Institute of the City Of Hope
$46,623,682OPERATING SUPPORT
City of Hope National Medical Center
$41,830,802OPERATING SUPPORT
The Translational Genomics Research Institute
$408,198OPERATING SUPPORT
Beckman Research Institute of the COH
$43,883,442Operating Support
City of Hope National Medical Center
$40,267,371Operating Support
The Translational Genomics Research Institute
$2,002,719Operating Support
City of Hope Medical Foundation
$11,199Operating Support
Beckman Research Institute of the COH
$48,529,658Operating Support
City of Hope National Medical Center
$26,214,443Operating Support
The Translational Genomics Research Institute
$233,678Operating Support
City of Hope Medical Foundation
$206,333Operating Support