To eliminate cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer through research, education, advocacy, and service.
American Cancer Society Inc pairs large-scale program support with a long pipeline of research and training grants. In the recent grants list, the biggest awards go to the American Cancer Society Cancer Action Network in Washington, DC, including $38,070,794 in 2025 and $36,352,310 in 2023, showing that advocacy and public-policy work sits alongside its research funding. The foundation also backs major academic medical centers and universities through extramural research and support/research awards, including $9,837,685 to Massachusetts General Hospital in Somerville, MA and $6,670,500 to Icahn School of Medicine at Mt Sinai in New York, NY. Its active programs point to a broad research agenda: investigator-initiated cancer studies, clinician-scientist development, post-baccalaureate training, institutional seed funding, and staged translational grants. The organization’s stated purpose is to eliminate cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering through research, education, advocacy, and service.
Cancer research is the clearest throughline. American Cancer Society Inc gave $6,719,500 to The University of Texas Health Science Center at San Antonio for extramural research in 2023, and $5,618,158 to Yale University for extramural research in 2024. It also funds independent investigators through Research Scholar Grants and institutional seed support through Institutional Research Grants. Training is another visible area: the ACS Center for Innovation in Cancer Research Training supports two-year post-baccalaureate cancer research training programs for participants preparing for doctoral study. Translational work appears in Mission Boost Grants, which move patient-focused research toward clinical impact. Patient-facing support is part of the portfolio as well, reflected in the foundation’s stated focus on rides, lodging, and helpline services.
Typical grant size clusters at $10,000 at the 25th percentile, $20,000 at the median, and $60,000 at the 75th percentile. The recent record shows both very large program awards and a broad base of research grants, with awards recurring across years to the same institutions and entities, such as Washington University, Yale University, and Dana Farber Cancer Institute. American Cancer Society Inc is classified as a regular funder and operates as a national grantmaker. Its active opportunities are described as unsolicited and application-based, including research grants, clinician-scientist development, institutional grants, and mission-oriented funding mechanisms.
$574M
$1.7B
$724.2M
$791.9M
Most grants fall between $10K and $60K, with a median of $20K.
25th Percentile
$10K
Median
$20K
75th Percentile
$60K
About 3% of grants go to recipients in NY.
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Grantmaking is national, and all recent grants shown go to US recipients. The highest concentration by state is New York, while Georgia accounts for 3% of grants. In the recent list, Washington, DC appears repeatedly through program support to the American Cancer Society Cancer Action Network, and New York City appears through Icahn School of Medicine at Mt Sinai and Columbia University. Other frequent recipient locations include Boston, New Haven, St Louis, and Philadelphia, indicating a strong mix of major academic medical centers and policy-focused grantees.
The foundation funds cancer research, prevention and risk-factor work, screening and early detection, patient support services, and community fundraising programs. Its active grant programs include investigator research, clinician-scientist development, post-baccalaureate training, institutional seed grants, and translational research support.
The grant-size distribution centers at $10,000 at the 25th percentile, $20,000 at the median, and $60,000 at the 75th percentile. The recent grants list also includes much larger awards for program support and research, showing a wide spread across grant types.
The recipient country distribution shown is entirely US-based: 2,059 grants, or 100.0%, go to US recipients. The active grant programs listed are also scoped to the United States.
Yes. The active programs include multiple unsolicited opportunities, such as American Cancer Society — Research Grants, Clinician Scientist Development Grant, Discovery Boost Grants, Research Scholar Grants, Institutional Research Grants, and Mission Boost Grants.
The recent grants list is dominated by academic medical centers, universities, and research institutions such as Massachusetts General Hospital, Yale University, Washington University, Columbia University, and Dana Farber Cancer Institute, alongside program support to the American Cancer Society Cancer Action Network in Washington, DC.
DR KAREN E KNUDSEN PHD
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| American Cancer Society Cancer Action Network | Washington, DC | $38,070,794 | 2025 | Program Support |
| Massachusetts General Hospital | Somerville, MA | $9,837,685 | 2025 | Support/Research |
| Icahn School Of Medicine At Mt Sinai | New York, NY | $6,670,500 | 2025 | Support/Research |
| Oregon Health & Science University | Portland, OR | $4,598,554 | 2025 | Extramural Research |
| Yale University | New Haven, CT | $4,516,757 | 2025 | Extramural Research |
| Washington University | St Louis, MO | $4,213,500 | 2025 | Extramural Research |
| University of Oklahoma Health Sciences Center | Oklahoma City, OK | $4,125,000 | 2025 | Support/Research |
| Brigham And Womens Hospital | Boston, MA | $3,681,743 | 2025 | Extramural Research |
| Ut Southwestern Medical Center | Dallas, TX | $3,452,000 | 2025 | Extramural Research |
| University of Alabama at Birmingham | Birmingham, AL | $3,204,500 | 2025 | Support/Research |
| Dana Farber Cancer Institute | Boston, MA | $3,193,000 | 2025 | Support/Research |
| Medical University Of South Carolina | Charleston, SC | $3,171,000 | 2025 | Support/Research |
| Ohio State University | Columbus, OH | $3,015,411 | 2025 | Extramural Research |
| U Of Tx Md Anderson Cancer Ctr | Houston, TX | $2,952,234 | 2025 | Extramural Research |
| Trustees of the University of Penn | Philadelphia, PA | $2,611,500 | 2025 | Support/Research |
| Duke University Health System Inc | Durham, NC | $2,520,500 | 2025 | Support/Research |
| University Of Utah Research Foundation | Salt Lake City, UT | $2,516,452 | 2025 | Extramural Research |
| University of Texas Health Science Center | San Antonio, TX | $2,389,500 | 2025 | Support/Research |
| Regents Of The University Of California at Irvine | Irvine, CA | $2,332,000 | 2025 | Extramural Research |
| The Cleveland Clinic Foundation | Cleveland, OH | $1,987,500 | 2025 | Support/Research |
| Board Of Trustees Of Leland Stanford Junior University | Redwood City, CA | $1,963,500 | 2025 | Support/Research |
| Fred Hutchinson Cancer Center | Seattle, WA | $1,926,000 | 2025 | Extramural Research |
| Weill Med College Of Cornell U | New York, NY | $1,831,000 | 2025 | Extramural Research |
| Univ Of Nebraska Medical Center | Omaha, NE | $1,824,000 | 2025 | Extramural Research |
| University of California San Francisco | San Francisco, CA | $1,781,250 | 2025 | Support/Research |
| President and Fellows Of Harvard College | Boston, MA | $1,760,000 | 2025 | Extramural Research |
| University Of Chicago | Chicago, IL | $1,619,000 | 2025 | Support/Research |
| Sloan - Kettering Institute For | New York, NY | $1,604,000 | 2025 | Extramural Research |
| Georgetown University | Washington, DC | $1,514,500 | 2025 | Extramural Research |
| Patient Advocate Foundation | Hampton, VA | $1,470,000 | 2025 | Patient Support |
| H Lee Moffitt Cancer Center And Research Institute Inc | Tampa, FL | $1,457,000 | 2025 | Extramural Research |
| Regents Of The Univ Of Minn | Minneapolis, MN | $1,393,000 | 2025 | Extramural Research |
| Institute for Cancer Research | Philadelphia, PA | $1,381,000 | 2025 | Extramural Research |
| University Of Arizona | Tucson, AZ | $1,347,500 | 2025 | Extramural Research |
| Univ Of Maryland Baltimore | Baltimore, MD | $1,317,000 | 2025 | Extramural Research |
| Columbia University | New York, NY | $1,313,500 | 2025 | Extramural Research |
| Trustees Of Boston Univ Bumc | Boston, MA | $1,286,200 | 2025 | Extramural Research |
| Sanford Burnham Prebys Medical Discovery Institute | La Jolla, CA | $1,231,062 | 2025 | Extramural Research |
| Baylor College Of Medicine Healthcare | Houston, TX | $1,108,500 | 2025 | Extramural Research |
| Board Of Regents On The Univ | Madison, WI | $1,078,000 | 2025 | Extramural Research |
| University of Kentucky Research Foundation | Cleveland, OH | $1,073,000 | 2025 | Support/Research |
| Wake Forest University Health Sciences | Winston Salem, NC | $1,059,036 | 2025 | Support/Research |
| University Of Miami | Coral Gables, FL | $1,040,000 | 2025 | Support/Research |
| American College Of Surgeons | Chicago, IL | $1,021,500 | 2025 | Support/Research |
| Trustees Of Dartmouth College | Hanover, NH | $1,020,000 | 2025 | Extramural Research |
| University Of Pittsburgh | Pittsburgh, PA | $1,019,079 | 2025 | Extramural Research |
| Beckman Research Institute of the City of Hope | Duarte, CA | $1,006,956 | 2025 | Support/Research |
| University Of Illinois | Urbana, IL | $987,250 | 2025 | Support/Research |
| University Of Illinois Chicago | Chicago, IL | $961,462 | 2025 | Extramural Research |
| Purdue University | Chicago, IL | $960,000 | 2025 | Extramural Research |
American Cancer Society Cancer Action Network
$38,070,794Program Support
Massachusetts General Hospital
$9,837,685Support/Research
Icahn School Of Medicine At Mt Sinai
$6,670,500Support/Research
Oregon Health & Science University
$4,598,554Extramural Research
Yale University
$4,516,757Extramural Research
Washington University
$4,213,500Extramural Research
University of Oklahoma Health Sciences Center
$4,125,000Support/Research
Brigham And Womens Hospital
$3,681,743Extramural Research
Ut Southwestern Medical Center
$3,452,000Extramural Research
University of Alabama at Birmingham
$3,204,500Support/Research
Dana Farber Cancer Institute
$3,193,000Support/Research
Medical University Of South Carolina
$3,171,000Support/Research
Ohio State University
$3,015,411Extramural Research
U Of Tx Md Anderson Cancer Ctr
$2,952,234Extramural Research
Trustees of the University of Penn
$2,611,500Support/Research
Duke University Health System Inc
$2,520,500Support/Research
University Of Utah Research Foundation
$2,516,452Extramural Research
University of Texas Health Science Center
$2,389,500Support/Research
Regents Of The University Of California at Irvine
$2,332,000Extramural Research
The Cleveland Clinic Foundation
$1,987,500Support/Research
Board Of Trustees Of Leland Stanford Junior University
$1,963,500Support/Research
Fred Hutchinson Cancer Center
$1,926,000Extramural Research
Weill Med College Of Cornell U
$1,831,000Extramural Research
Univ Of Nebraska Medical Center
$1,824,000Extramural Research
University of California San Francisco
$1,781,250Support/Research
President and Fellows Of Harvard College
$1,760,000Extramural Research
University Of Chicago
$1,619,000Support/Research
Sloan - Kettering Institute For
$1,604,000Extramural Research
Georgetown University
$1,514,500Extramural Research
Patient Advocate Foundation
$1,470,000Patient Support
H Lee Moffitt Cancer Center And Research Institute Inc
$1,457,000Extramural Research
Regents Of The Univ Of Minn
$1,393,000Extramural Research
Institute for Cancer Research
$1,381,000Extramural Research
University Of Arizona
$1,347,500Extramural Research
Univ Of Maryland Baltimore
$1,317,000Extramural Research
Columbia University
$1,313,500Extramural Research
Trustees Of Boston Univ Bumc
$1,286,200Extramural Research
Sanford Burnham Prebys Medical Discovery Institute
$1,231,062Extramural Research
Baylor College Of Medicine Healthcare
$1,108,500Extramural Research
Board Of Regents On The Univ
$1,078,000Extramural Research
University of Kentucky Research Foundation
$1,073,000Support/Research
Wake Forest University Health Sciences
$1,059,036Support/Research
University Of Miami
$1,040,000Support/Research
American College Of Surgeons
$1,021,500Support/Research
Trustees Of Dartmouth College
$1,020,000Extramural Research
University Of Pittsburgh
$1,019,079Extramural Research
Beckman Research Institute of the City of Hope
$1,006,956Support/Research
University Of Illinois
$987,250Support/Research
University Of Illinois Chicago
$961,462Extramural Research
Purdue University
$960,000Extramural Research