Human Services Grants in South Carolina

215 foundations fund human services programs in South Carolina. See who they are, what they give, and how to reach them.

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These foundations have a track record of funding human services work in South Carolina, based on IRS 990 grant data. Use the list below to find funders aligned with your mission, then sign up free to see how well your nonprofit fits each one.

Open Grant Opportunities

Live programs funding human services in South Carolina that your nonprofit can apply to now.

Open nowCloses in 18 days (Aug 31, 2026)Award: $2K – $6K

Annual Ramlose Foundation Grant

From George A Ramlose Foundation

Early EducationHuman ServicesSpecial Needs and Disabilities+1 more

Who can apply: Applicants must be recognized as a 501(c)(3) nonprofit organization and based in Massachusetts, Maine, Connecticut, Rhode Island, Vermont, New Hampshire, Georgia, South Carolina, New Jersey, or Pennsylvania. Preference is given to small organizations and newer organizations approaching a breakthrough moment. Organizations with annual operating budgets over $3 million are seldom funded. Organizations that have received Ramlose Foundation funding for three consecutive years are not eligible to apply in 2026.

Open nowCloses in 18 days (Aug 31, 2026)Award: $2K – $6K

Annual Grant Program

From George A Ramlose Foundation

Early EducationHuman ServicesSpecial Needs and Disabilities+1 more

Who can apply: Must be a 501(c)(3) nonprofit organization based in Massachusetts, Maine, Connecticut, Rhode Island, Vermont, New Hampshire, Georgia, South Carolina, New Jersey, or Pennsylvania. Organizations with an annual operating budget over $3 million are rarely funded. Organizations that have received Ramlose Foundation funding for three consecutive years are not eligible to apply in 2026.

Open nowRolling / open intakeAward: $1K – $3K

Legacy Grants

From Elmer L & Eleanor J Andersen Foundation

arts and humanitiescommunicationseducation+4 more

Who can apply: Nonprofit organizations whose work aligns with the foundation's mission, legacy grant focus areas, and other restrictions/deadlines. Applicants must complete an eligibility quiz before receiving access to the application form and submission instructions.

Open nowCloses Sep 30, 2026

Grant Application

From Daniel-Mickel Foundation

educationarts and culturehealth and human services+1 more

Who can apply: Open to nonprofit organizations that meet the Foundation's Grant Guidelines.

Open nowCloses Sep 30, 2026Award: $10K – $50K

Holleman Foundation — General Grants

From Holleman Roy & Marian Fdn-Main

animal welfarelibrary scienceeducation+3 more

Who can apply: Organizations must be tax-exempt under Section 501(c)(3) of the Internal Revenue Code. No indication that individuals or non-501(c)(3) entities are eligible.

Open nowCloses Oct 1, 2026

Recipient Application

From Rollie and Barbara Anderson Family Foundation

Christian valuesEvangelistic Christian beliefsEducation capital projects+7 more

Who can apply: Must be a qualified 501(c)(3) charity. Organizations that support evangelistic Christian values and beliefs are preferred.

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Deadlines and program details come from public sources and can change. Always confirm on the funder's official site before applying.

Largest Human Services in South Carolina Foundations

BLUE MERIDIAN PARTNERS INC

NEW YORK, NY

Annual Giving

$352.9M

Total Assets

$2.1B

Median Grant

$2.2M

P12National
DELIVERING GOOD INC

NEW YORK, NY

Annual Giving

$132.4M

Total Assets

$3.2M

Median Grant

$52K

P190National
FARMLINK PROJECT

LOS ANGELES, CA

Annual Giving

$106.7M

Total Assets

$9.5M

Median Grant

$138K

P20National
THDF II Inc DBA The Home Depot Foundation & Homer Fund

Atlanta, GA

Annual Giving

$69.4M

Total Assets

$267.4M

Median Grant

$104K

P60Regional
TIDES CENTER

SAN FRANCISCO, CA

Annual Giving

$55.3M

Total Assets

$297.4M

Median Grant

$44K

P20National
NATIONAL URBAN LEAGUE INC

NEW YORK, NY

Annual Giving

$54.8M

Total Assets

$280.5M

Median Grant

$39K

P220National
National Council of YMCAs of the USA

Chicago, IL

Annual Giving

$44.1M

Total Assets

$260.5M

Median Grant

$34K

P270National
PURE INC

BENTONVILLE, AR

Annual Giving

$27.3M

Total Assets

$1.4M

Median Grant

$47K

P12National
EDWARD CHARLES FOUNDATION

BEVERLY HILLS, CA

Annual Giving

$24.5M

Total Assets

$63.5M

Median Grant

$22K

P99National
EASTER SEALS INC

CHICAGO, IL

Annual Giving

$23.9M

Total Assets

$40.9M

Median Grant

$57K

P80National
YOUTHBRIDGE COMMUNITY FOUNDATION

SAINT LOUIS, MO

Annual Giving

$19.7M

Total Assets

$105.2M

Median Grant

$24K

P70ZRegional
For the Girls Inc

Wheaton, MD

Annual Giving

$19.5M

Total Assets

$4M

Median Grant

$16K

P85National
Carequest Foundation Inc

BOSTON, MA

Annual Giving

$14.5M

Total Assets

$21.1M

Median Grant

P20ZNational
FRONTSTREAM GLOBAL FUND

WASHINGTON, DC

Annual Giving

$13.4M

Total Assets

$421K

Median Grant

$14K

P20National
SOLES4SOULS INC

OLD HICKORY, TN

Annual Giving

$12.5M

Total Assets

$42.8M

Median Grant

$13K

P60National
CHILDREN'S TRUST OF SOUTH CAROLINA

COLUMBIA, SC

Annual Giving

$11.5M

Total Assets

$11.4M

Median Grant

$119K

P34JLocal
UNITED WAY OF DANE COUNTY INC

Madison, WI

Annual Giving

$11.4M

Total Assets

$21.9M

Median Grant

$22K

P21Local
ALLIANCE FOR EARLY SUCCESS FKA BIRTH TO FIVE POLICY ALLIANCE

WASHINGTON, DC

Annual Giving

$11.3M

Total Assets

$26.4M

Median Grant

$75K

P30National
MOORE IMPACT INC

DENVER, CO

Annual Giving

$11.1M

Total Assets

$8.5M

Median Grant

$50K

P20National
AARP Foundation

Washington, DC

Annual Giving

$11.1M

Total Assets

$728M

Median Grant

$30K

P81National
THE VERTEX FOUNDATION INC

Boston, MA

Annual Giving

$10M

Total Assets

$2.6M

Median Grant

$5K

P20National
Fund for Nonviolence

Berkeley, CA

Annual Giving

$9.5M

Total Assets

$73.2M

Median Grant

$50K

P20ZNational
THE FOUNDATION FOR ENHANCING COMMUNITIES

HARRISBURG, PA

Annual Giving

$7.7M

Total Assets

$161M

Median Grant

$11K

P12Local
TINY BLUE DOT INC

WEST HOLLYWOOD, CA

Annual Giving

$7.2M

Total Assets

$79.2M

Median Grant

$305K

P20National
NATIONAL DIAPER BANK NETWORK INC

NEW HAVEN, CT

Annual Giving

$7M

Total Assets

$4.2M

Median Grant

$30K

P20National

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