Open nowCloses in 3 days (Jun 30, 2026)
General Community Grants
EducationArts and cultureHealth and human services+2 more
Who can apply: Nonprofit organizations that meet the Foundation's Grant Guidelines (see guidelines PDF).
Human Services Grants in South Carolina
177 foundations fund human services programs in South Carolina. See who they are, what they give, and how to reach them.
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These foundations have a track record of funding human services work in South Carolina, based on IRS 990 grant data. Use the list below to find funders aligned with your mission, then sign up free to see how well your nonprofit fits each one.
Open Grant Opportunities
Live programs funding human services in South Carolina that your nonprofit can apply to now.
Open nowCloses in 4 days (Jul 1, 2026)
Annual Grant Program (The Doyle Foundation, Inc.)
General charitable purposesCommunity bettermentHuman services+3 more
Who can apply: Must be a 501(c)(3) organization incorporated in the United States. Only complete proposals submitted in the required online format will be considered. Organizations may not apply for more than one project at a time.
Open nowCloses in 13 days (Jul 10, 2026)Award: $25K+
General, Medical, and Research Grants (Over $25,000) — Letter of Inquiry (LOI)
medical researchmedical educationgeneral education+1 more
Who can apply: For requests over $25,000, applicants must submit an LOI with required program details and contact information. LOIs and requested applications are reviewed quarterly prior to board meetings.
Open nowCloses Jul 30, 2026Award: Up to $450K
OVC FY 2026 Increasing Services for American Indian and Alaska Native Victims of Human Trafficking in Urban Centers Program
From National Council of Urban Indian Health
human trafficking servicesvictim servicescase management+3 more
Who can apply: UIOs may apply under Category 1 for direct services; Category 2 supports capacity building among urban Indian-serving service providers. No cost-share required.
Open nowCloses Aug 10, 2026Award: $10K – $50K
Philip L. Van Every Foundation General Grant Program
From Philip L Van Every Foundation
Human ServicesEducationHealthcare+12 more
Who can apply: Established organizations located in North or South Carolina, classified as a public charity and qualified under section 501(c)(3) of the Internal Revenue Code. The Foundation does not fund organizations with pending 501(c)(3) status, fiscal agents, individuals, scholarships, loans, political organizations, events, conferences, meetings, fellowships, seed money/start-up grants, or operating funds including salaries.
Open nowRolling / open intakeAward: $1K – $3K
Legacy Grants
From Elmer L & Eleanor J Andersen Foundation
arts and humanitiescommunicationseducation+4 more
Who can apply: Nonprofit organizations whose work aligns with the foundation's mission, legacy grant focus areas, and other restrictions/deadlines. Applicants must complete an eligibility quiz before receiving access to the application form and submission instructions.
Want every open grant matched to your nonprofit — not just these? Kindora scores your fit and tracks the deadlines for you.
Find My Grant MatchesDeadlines and program details come from public sources and can change. Always confirm on the funder's official site before applying.
Largest Human Services in South Carolina Foundations
| Foundation | Location | Annual Giving | Total Assets | Median Grant | NTEE | Scope |
|---|---|---|---|---|---|---|
| BLUE MERIDIAN PARTNERS INC | NEW YORK, NY | $352.9M | $2.1B | $2.2M | P12 | National |
| DELIVERING GOOD INC | NEW YORK, NY | $132.4M | $3.2M | $52K | P190 | National |
| FARMLINK PROJECT | LOS ANGELES, CA | $106.7M | $9.5M | $138K | P20 | National |
| TIDES CENTER | SAN FRANCISCO, CA | $55.3M | $297.4M | $44K | P20 | National |
| NATIONAL URBAN LEAGUE INC | NEW YORK, NY | $54.8M | $280.5M | $39K | P220 | National |
| THDF II Inc DBA The Home Depot Foundation & Homer Fund | Atlanta, GA | $53.9M | $238.8M | $104K | P60 | Regional |
| National Council of YMCAs of the USA | Chicago, IL | $44.1M | $260.5M | $34K | P270 | National |
| BOULDER CREST FOUNDATION | BLUEMONT, VA | $32.9M | $44.4M | $600K | P80 | Regional |
| PURE INC | BENTONVILLE, AR | $27.3M | $1.4M | $47K | P12 | Regional |
| EDWARD CHARLES FOUNDATION | BEVERLY HILLS, CA | $24.5M | $63.5M | $22K | P99 | National |
| EASTER SEALS INC | CHICAGO, IL | $23.9M | $40.9M | $57K | P80 | National |
| YOUTHBRIDGE COMMUNITY FOUNDATION | SAINT LOUIS, MO | $19.7M | $105.2M | $24K | P70Z | Regional |
| SOLES4SOULS INC | OLD HICKORY, TN | $17.5M | $44.9M | $13K | P60 | National |
| FRONTSTREAM GLOBAL FUND | WASHINGTON, DC | $14.9M | $447K | $14K | P20 | National |
| CHILDREN'S TRUST OF SOUTH CAROLINA | COLUMBIA, SC | $11.5M | $11.4M | $119K | P34J | Local |
| UNITED WAY OF DANE COUNTY INC | Madison, WI | $11.4M | $21.9M | $22K | P21 | Local |
| ALLIANCE FOR EARLY SUCCESS FKA BIRTH TO FIVE POLICY ALLIANCE | WASHINGTON, DC | $11.3M | $26.4M | $75K | P30 | National |
| MOORE IMPACT INC | DENVER, CO | $11.1M | $8.5M | $50K | P20 | National |
| AARP Foundation | Washington, DC | $11.1M | $728M | $30K | P81 | National |
| THE VERTEX FOUNDATION INC | Boston, MA | $10M | $2.6M | $5K | P20 | National |
| Fund for Nonviolence | Berkeley, CA | $9.5M | $73.2M | $50K | P20Z | National |
| UNITED WAY OF BERGEN COUNTY | PARAMUS, NJ | $8M | $31.5M | $10K | P21 | National |
| THE FOUNDATION FOR ENHANCING COMMUNITIES | HARRISBURG, PA | $7.7M | $161M | $11K | P12 | Local |
| TINY BLUE DOT INC | WEST HOLLYWOOD, CA | $7.2M | $79.2M | $305K | P20 | National |
| NATIONAL DIAPER BANK NETWORK INC | NEW HAVEN, CT | $7M | $4.2M | $30K | P20 | National |
BLUE MERIDIAN PARTNERS INC
NEW YORK, NY
Annual Giving
$352.9M
Total Assets
$2.1B
Median Grant
$2.2M
P12National
NATIONAL URBAN LEAGUE INC
NEW YORK, NY
Annual Giving
$54.8M
Total Assets
$280.5M
Median Grant
$39K
P220National
THDF II Inc DBA The Home Depot Foundation & Homer Fund
Atlanta, GA
Annual Giving
$53.9M
Total Assets
$238.8M
Median Grant
$104K
P60Regional
National Council of YMCAs of the USA
Chicago, IL
Annual Giving
$44.1M
Total Assets
$260.5M
Median Grant
$34K
P270National
BOULDER CREST FOUNDATION
BLUEMONT, VA
Annual Giving
$32.9M
Total Assets
$44.4M
Median Grant
$600K
P80Regional
EDWARD CHARLES FOUNDATION
BEVERLY HILLS, CA
Annual Giving
$24.5M
Total Assets
$63.5M
Median Grant
$22K
P99National
YOUTHBRIDGE COMMUNITY FOUNDATION
SAINT LOUIS, MO
Annual Giving
$19.7M
Total Assets
$105.2M
Median Grant
$24K
P70ZRegional
FRONTSTREAM GLOBAL FUND
WASHINGTON, DC
Annual Giving
$14.9M
Total Assets
$447K
Median Grant
$14K
P20National
CHILDREN'S TRUST OF SOUTH CAROLINA
COLUMBIA, SC
Annual Giving
$11.5M
Total Assets
$11.4M
Median Grant
$119K
P34JLocal
UNITED WAY OF DANE COUNTY INC
Madison, WI
Annual Giving
$11.4M
Total Assets
$21.9M
Median Grant
$22K
P21Local
ALLIANCE FOR EARLY SUCCESS FKA BIRTH TO FIVE POLICY ALLIANCE
WASHINGTON, DC
Annual Giving
$11.3M
Total Assets
$26.4M
Median Grant
$75K
P30National
THE FOUNDATION FOR ENHANCING COMMUNITIES
HARRISBURG, PA
Annual Giving
$7.7M
Total Assets
$161M
Median Grant
$11K
P12Local
NATIONAL DIAPER BANK NETWORK INC
NEW HAVEN, CT
Annual Giving
$7M
Total Assets
$4.2M
Median Grant
$30K
P20National
Human Services grants by state
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