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    Answer Als

    ActiveDiseases & Disorders
    NEW ORLEANS, LAWebsite8004902375

    About Answer Als

    Answer ALS is dedicated to accelerating the discovery of treatments and cures for amyotrophic lateral sclerosis (ALS) by uniting a global community of researchers, patients, and advocates in an open, collaborative quest for answers. Through the Neuromine platform it shares large multi-omics datasets, biosamples, and patient-derived iPSC lines to enable biomarker discovery, risk-factor identification, and therapy testing in patient-relevant models.

    Focus Areas

    ALS researchneurodegenerative disease researchopen science / data sharingbiobanking and iPSC resourcesAI-driven drug discovery

    Who They Fund

    people living with ALS (patients)ALS researchers and research teamsmedical research institutions/clinics focused on ALS

    Funding Style

    disease-specific research funding

    About Answer Als

    Answer Als centers its giving on ALS research, and its recent grant record shows a heavy concentration in large project grants to biomedical research institutions and research vendors. The single largest recent award in the data is $1,029,803 to John Hopkins University School of Medicine in Baltimore for ALS research, followed by a $946,512 grant to Cedars Sinai Hospital in Los Angeles for the same purpose. Those awards sit alongside other substantial commitments to ALS-focused work at the same institutions, including a $724,850 grant to John Hopkins University School of Medicine and a $523,889 grant to Cedars Sinai Hospital. The foundation’s approach is not limited to academic labs. It also funds the infrastructure around ALS science, including support for On Point Scientific, Diagenode LLC, Microsoft, and Antares Formerly Contingasoft, all described as grants to fund ALS research. That mix aligns with Answer Als’s open-science model, which uses the Neuromine platform to share multi-omics data, biosamples, and patient-derived iPSC lines for biomarker discovery, risk-factor identification, and therapy testing. The result is a funder focused on accelerating ALS treatment discovery through both direct research support and enabling research tools.

    What Answer Als Funds

    Answer Als gives across several ALS research functions, with a clear emphasis on the tools and institutions that move the science forward. In translational and clinical research, it awarded $1,029,803 to John Hopkins University School of Medicine for ALS research and another $946,512 to Cedars Sinai Hospital for the same purpose. It also supports the technical side of data generation and analysis. The foundation gave $487,346 to On Point Scientific and $229,531 to Diagenode LLC, each described as grants to fund ALS research. A separate $174,099 grant went to Microsoft for ALS research, showing that software and computational support are part of the portfolio. The foundation also funds Louisiana-based research capacity: Louisiana State University received $41,973 and $41,425, and Pennington Biomedical Research Center received $41,947, all for ALS research. That pattern fits Answer Als’s broader open-science and data-sharing orientation.

    How Answer Als Gives

    Answer Als makes relatively large project grants. In the recent data, the typical grant size is $50,623 at the 25th percentile, $213,700 at the median, and $556,212 at the 75th percentile. The record shows repeated support for the same recipients across years and within 2025, including John Hopkins University School of Medicine and Cedars Sinai Hospital, which indicates ongoing relationships rather than one-off awards. The foundation operates as a grantmaker rather than an individual-giving or PRIs-focused funder. Its active program, Neuromine Data & iPSC Access, does not accept unsolicited applications. The grant descriptions consistently frame awards as project-restricted support for ALS research, data access, or related research infrastructure.

    Financial Snapshot

    Annual Giving

    $4.6M

    Total Assets

    $7.4M

    Total Revenue

    $2.8M

    Total Expenses

    $3.2M

    Typical Grant Size

    Most grants fall between $51K and $556K, with a median of $214K.

    25th Percentile

    $51K

    Median

    $214K

    75th Percentile

    $556K

    Geographic Reach

    National6 states funded

    About 13% of grants go to recipients in CA.

    Funding intensity
    Low
    High
    Headquarters

    Leadership

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    Privacy PolicyTerms of ServiceSystem Status
    EIN (Tax ID): 47-1643994Latest Form 990: 2025Total assets: $7.4M3 filings on recordFind their full 990 filing →
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    project-restricted grants
    biomedical/clinical research support

    Topics

    ALS (amyotrophic lateral sclerosis) researchneurodegenerative disease researchtherapeutic development for ALSclinical and translational research

    Where Answer Als Makes Grants

    Answer Als gives nationally, with all listed recent grants going to U.S. recipients. California appears as the top state by grant count, driven in part by awards to Cedars Sinai Hospital and other California-based recipients. Maryland also stands out through multiple awards to Baltimore and Bethesda institutions, while Louisiana shows local support in New Orleans and Baton Rouge. Other recipient locations include Montague and Denville, New Jersey; Cambridge, Massachusetts; Redmond, Washington; and New York, New York.

    Frequently Asked Questions About Answer Als

    What areas does Answer Als fund?

    Its giving is centered on ALS research, with related support for neurodegenerative disease research, open science and data sharing, biobanking and iPSC resources, and AI-driven drug discovery. The recent grants show support for research institutions, data platforms, and research infrastructure tied to ALS science.

    Does Answer Als accept unsolicited grant applications?

    No. The active Neuromine Data & iPSC Access program is listed as not accepting unsolicited requests.

    What is the typical grant size?

    The recent grant distribution shows a 25th percentile of $50,623, a median of $213,700, and a 75th percentile of $556,212. That suggests a portfolio built around mid-sized and larger project grants.

    Where does Answer Als give most often?

    Its giving is national, and the top state by grant count is California. Louisiana accounts for 12% of grants to recipients in the HQ state, while all listed recent grants went to U.S. recipients.

    Does Answer Als fund the same organizations more than once?

    Yes. John Hopkins University School of Medicine appears multiple times in the recent data, including awards of $1,029,803, $724,850, and $500,000. Cedars Sinai Hospital also appears more than once, with grants of $946,512 and $523,889.

    Latest 990 Filing

    2025

    Source: IRS Form 990-PF, fiscal year 2025.

    Recent Grants

    Most recent grants reported to the IRS.

    RecipientLocationAmountYearPurpose
    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINEBALTIMORE, MD$1,029,8032025GRANT TO FUND ALS RESEARCH.
    CEDARS SINAI HOSPITALLOS ANGELES, CA$946,5122025GRANT TO FUND ALS RESEARCH.
    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINEBALTIMORE, MD$724,8502025GRANT TO FUND ALS RESEARCH.
    CEDARS SINAI HOSPITALLOS ANGELES, CA$523,8892025GRANT TO FUND ALS RESEARCH.
    ON POINT SCIENTIFICMONTAGUE, NJ$487,3462025GRANT TO FUND ALS RESEARCH.
    DIAGENODE LLCDENVILLE, NJ$229,5312025GRANT TO FUND ALS RESEARCH.
    DIAGENODE LLCDENVILLE, NJ$227,4002025GRANT TO FUND ALS RESEARCH.
    MICROSOFTREDMOND, WA$174,0992025GRANT TO FUND ALS RESEARCH.
    ANTARES FORMERLY CONTINGASOFTNEW ORLEANS, LA$60,6782025GRANT TO FUND ALS RESEARCH.
    ON POINT SCIENTIFICMONTAGUE, NJ$53,6892025GRANT TO FUND ALS RESEARCH.
    LOUISIANA STATE UNIVERSITYBATON ROUGE, LA$41,9732025GRANT TO FUND ALS RESEARCH.
    PENNINGTON BIOMEDICAL RESEARCH CENTERBATON ROUGE, LA$41,9472025GRANT TO FUND ALS RESEARCH.
    LOUISIANA STATE UNIVERSITYBATON ROUGE, LA$41,4252025GRANT TO FUND ALS RESEARCH.
    ALMAGUNEW YORK, NY$15,0002025GRANT TO FUND ALS RESEARCH.
    ALMAGUNEW YORK, NY$14,9002025GRANT TO FUND ALS RESEARCH.
    FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTHBETHESDA, MD$10,0002025GRANT TO FUND ALS RESEARCH.
    UNIVERSITY OF NEW ORLEANS OFFICE OF RESEARCHNEW ORLEANS, LA$6,9952025GRANT TO FUND ALS RESEARCH.
    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINEBALTIMORE, MD$500,0002023GRANT TO FUND ALS RESEARCH.
    MASSACHUSETTS INSTITUTE OF TECHNOLOGY- MCGOVERN INSTITUTECAMBRIDGE, MA$200,0002023DONATION TO ALS RESEARCH.

    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE

    $1,029,803
    BALTIMORE, MD2025

    GRANT TO FUND ALS RESEARCH.

    CEDARS SINAI HOSPITAL

    $946,512
    LOS ANGELES, CA2025

    GRANT TO FUND ALS RESEARCH.

    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE

    $724,850
    BALTIMORE, MD2025

    GRANT TO FUND ALS RESEARCH.

    CEDARS SINAI HOSPITAL

    $523,889
    LOS ANGELES, CA2025

    GRANT TO FUND ALS RESEARCH.

    ON POINT SCIENTIFIC

    $487,346
    MONTAGUE, NJ2025

    GRANT TO FUND ALS RESEARCH.

    DIAGENODE LLC

    $229,531
    DENVILLE, NJ2025

    GRANT TO FUND ALS RESEARCH.

    DIAGENODE LLC

    $227,400
    DENVILLE, NJ2025

    GRANT TO FUND ALS RESEARCH.

    MICROSOFT

    $174,099
    REDMOND, WA2025

    GRANT TO FUND ALS RESEARCH.

    ANTARES FORMERLY CONTINGASOFT

    $60,678
    NEW ORLEANS, LA2025

    GRANT TO FUND ALS RESEARCH.

    ON POINT SCIENTIFIC

    $53,689
    MONTAGUE, NJ2025

    GRANT TO FUND ALS RESEARCH.

    LOUISIANA STATE UNIVERSITY

    $41,973
    BATON ROUGE, LA2025

    GRANT TO FUND ALS RESEARCH.

    PENNINGTON BIOMEDICAL RESEARCH CENTER

    $41,947
    BATON ROUGE, LA2025

    GRANT TO FUND ALS RESEARCH.

    LOUISIANA STATE UNIVERSITY

    $41,425
    BATON ROUGE, LA2025

    GRANT TO FUND ALS RESEARCH.

    ALMAGU

    $15,000
    NEW YORK, NY2025

    GRANT TO FUND ALS RESEARCH.

    ALMAGU

    $14,900
    NEW YORK, NY2025

    GRANT TO FUND ALS RESEARCH.

    FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTH

    $10,000
    BETHESDA, MD2025

    GRANT TO FUND ALS RESEARCH.

    UNIVERSITY OF NEW ORLEANS OFFICE OF RESEARCH

    $6,995
    NEW ORLEANS, LA2025

    GRANT TO FUND ALS RESEARCH.

    JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE

    $500,000
    BALTIMORE, MD2023

    GRANT TO FUND ALS RESEARCH.

    MASSACHUSETTS INSTITUTE OF TECHNOLOGY- MCGOVERN INSTITUTE

    $200,000
    CAMBRIDGE, MA2023

    DONATION TO ALS RESEARCH.