Answer ALS is dedicated to accelerating the discovery of treatments and cures for amyotrophic lateral sclerosis (ALS) by uniting a global community of researchers, patients, and advocates in an open, collaborative quest for answers. Through the Neuromine platform it shares large multi-omics datasets, biosamples, and patient-derived iPSC lines to enable biomarker discovery, risk-factor identification, and therapy testing in patient-relevant models.
Answer Als centers its giving on ALS research, and its recent grant record shows a heavy concentration in large project grants to biomedical research institutions and research vendors. The single largest recent award in the data is $1,029,803 to John Hopkins University School of Medicine in Baltimore for ALS research, followed by a $946,512 grant to Cedars Sinai Hospital in Los Angeles for the same purpose. Those awards sit alongside other substantial commitments to ALS-focused work at the same institutions, including a $724,850 grant to John Hopkins University School of Medicine and a $523,889 grant to Cedars Sinai Hospital. The foundation’s approach is not limited to academic labs. It also funds the infrastructure around ALS science, including support for On Point Scientific, Diagenode LLC, Microsoft, and Antares Formerly Contingasoft, all described as grants to fund ALS research. That mix aligns with Answer Als’s open-science model, which uses the Neuromine platform to share multi-omics data, biosamples, and patient-derived iPSC lines for biomarker discovery, risk-factor identification, and therapy testing. The result is a funder focused on accelerating ALS treatment discovery through both direct research support and enabling research tools.
Answer Als gives across several ALS research functions, with a clear emphasis on the tools and institutions that move the science forward. In translational and clinical research, it awarded $1,029,803 to John Hopkins University School of Medicine for ALS research and another $946,512 to Cedars Sinai Hospital for the same purpose. It also supports the technical side of data generation and analysis. The foundation gave $487,346 to On Point Scientific and $229,531 to Diagenode LLC, each described as grants to fund ALS research. A separate $174,099 grant went to Microsoft for ALS research, showing that software and computational support are part of the portfolio. The foundation also funds Louisiana-based research capacity: Louisiana State University received $41,973 and $41,425, and Pennington Biomedical Research Center received $41,947, all for ALS research. That pattern fits Answer Als’s broader open-science and data-sharing orientation.
Answer Als makes relatively large project grants. In the recent data, the typical grant size is $50,623 at the 25th percentile, $213,700 at the median, and $556,212 at the 75th percentile. The record shows repeated support for the same recipients across years and within 2025, including John Hopkins University School of Medicine and Cedars Sinai Hospital, which indicates ongoing relationships rather than one-off awards. The foundation operates as a grantmaker rather than an individual-giving or PRIs-focused funder. Its active program, Neuromine Data & iPSC Access, does not accept unsolicited applications. The grant descriptions consistently frame awards as project-restricted support for ALS research, data access, or related research infrastructure.
$4.6M
$7.4M
$2.8M
$3.2M
Most grants fall between $51K and $556K, with a median of $214K.
25th Percentile
$51K
Median
$214K
75th Percentile
$556K
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Answer Als gives nationally, with all listed recent grants going to U.S. recipients. California appears as the top state by grant count, driven in part by awards to Cedars Sinai Hospital and other California-based recipients. Maryland also stands out through multiple awards to Baltimore and Bethesda institutions, while Louisiana shows local support in New Orleans and Baton Rouge. Other recipient locations include Montague and Denville, New Jersey; Cambridge, Massachusetts; Redmond, Washington; and New York, New York.
Its giving is centered on ALS research, with related support for neurodegenerative disease research, open science and data sharing, biobanking and iPSC resources, and AI-driven drug discovery. The recent grants show support for research institutions, data platforms, and research infrastructure tied to ALS science.
No. The active Neuromine Data & iPSC Access program is listed as not accepting unsolicited requests.
The recent grant distribution shows a 25th percentile of $50,623, a median of $213,700, and a 75th percentile of $556,212. That suggests a portfolio built around mid-sized and larger project grants.
Its giving is national, and the top state by grant count is California. Louisiana accounts for 12% of grants to recipients in the HQ state, while all listed recent grants went to U.S. recipients.
Yes. John Hopkins University School of Medicine appears multiple times in the recent data, including awards of $1,029,803, $724,850, and $500,000. Cedars Sinai Hospital also appears more than once, with grants of $946,512 and $523,889.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE | BALTIMORE, MD | $1,029,803 | 2025 | GRANT TO FUND ALS RESEARCH. |
| CEDARS SINAI HOSPITAL | LOS ANGELES, CA | $946,512 | 2025 | GRANT TO FUND ALS RESEARCH. |
| JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE | BALTIMORE, MD | $724,850 | 2025 | GRANT TO FUND ALS RESEARCH. |
| CEDARS SINAI HOSPITAL | LOS ANGELES, CA | $523,889 | 2025 | GRANT TO FUND ALS RESEARCH. |
| ON POINT SCIENTIFIC | MONTAGUE, NJ | $487,346 | 2025 | GRANT TO FUND ALS RESEARCH. |
| DIAGENODE LLC | DENVILLE, NJ | $229,531 | 2025 | GRANT TO FUND ALS RESEARCH. |
| DIAGENODE LLC | DENVILLE, NJ | $227,400 | 2025 | GRANT TO FUND ALS RESEARCH. |
| MICROSOFT | REDMOND, WA | $174,099 | 2025 | GRANT TO FUND ALS RESEARCH. |
| ANTARES FORMERLY CONTINGASOFT | NEW ORLEANS, LA | $60,678 | 2025 | GRANT TO FUND ALS RESEARCH. |
| ON POINT SCIENTIFIC | MONTAGUE, NJ | $53,689 | 2025 | GRANT TO FUND ALS RESEARCH. |
| LOUISIANA STATE UNIVERSITY | BATON ROUGE, LA | $41,973 | 2025 | GRANT TO FUND ALS RESEARCH. |
| PENNINGTON BIOMEDICAL RESEARCH CENTER | BATON ROUGE, LA | $41,947 | 2025 | GRANT TO FUND ALS RESEARCH. |
| LOUISIANA STATE UNIVERSITY | BATON ROUGE, LA | $41,425 | 2025 | GRANT TO FUND ALS RESEARCH. |
| ALMAGU | NEW YORK, NY | $15,000 | 2025 | GRANT TO FUND ALS RESEARCH. |
| ALMAGU | NEW YORK, NY | $14,900 | 2025 | GRANT TO FUND ALS RESEARCH. |
| FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTH | BETHESDA, MD | $10,000 | 2025 | GRANT TO FUND ALS RESEARCH. |
| UNIVERSITY OF NEW ORLEANS OFFICE OF RESEARCH | NEW ORLEANS, LA | $6,995 | 2025 | GRANT TO FUND ALS RESEARCH. |
| JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE | BALTIMORE, MD | $500,000 | 2023 | GRANT TO FUND ALS RESEARCH. |
| MASSACHUSETTS INSTITUTE OF TECHNOLOGY- MCGOVERN INSTITUTE | CAMBRIDGE, MA | $200,000 | 2023 | DONATION TO ALS RESEARCH. |
JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE
$1,029,803GRANT TO FUND ALS RESEARCH.
CEDARS SINAI HOSPITAL
$946,512GRANT TO FUND ALS RESEARCH.
JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE
$724,850GRANT TO FUND ALS RESEARCH.
CEDARS SINAI HOSPITAL
$523,889GRANT TO FUND ALS RESEARCH.
ON POINT SCIENTIFIC
$487,346GRANT TO FUND ALS RESEARCH.
DIAGENODE LLC
$229,531GRANT TO FUND ALS RESEARCH.
DIAGENODE LLC
$227,400GRANT TO FUND ALS RESEARCH.
MICROSOFT
$174,099GRANT TO FUND ALS RESEARCH.
ANTARES FORMERLY CONTINGASOFT
$60,678GRANT TO FUND ALS RESEARCH.
ON POINT SCIENTIFIC
$53,689GRANT TO FUND ALS RESEARCH.
LOUISIANA STATE UNIVERSITY
$41,973GRANT TO FUND ALS RESEARCH.
PENNINGTON BIOMEDICAL RESEARCH CENTER
$41,947GRANT TO FUND ALS RESEARCH.
LOUISIANA STATE UNIVERSITY
$41,425GRANT TO FUND ALS RESEARCH.
ALMAGU
$15,000GRANT TO FUND ALS RESEARCH.
ALMAGU
$14,900GRANT TO FUND ALS RESEARCH.
FOUNDATION FOR THE NATIONAL INSTITUTES OF HEALTH
$10,000GRANT TO FUND ALS RESEARCH.
UNIVERSITY OF NEW ORLEANS OFFICE OF RESEARCH
$6,995GRANT TO FUND ALS RESEARCH.
JOHN HOPKINS UNIVERSITY SCHOOL OF MEDICINE
$500,000GRANT TO FUND ALS RESEARCH.
MASSACHUSETTS INSTITUTE OF TECHNOLOGY- MCGOVERN INSTITUTE
$200,000DONATION TO ALS RESEARCH.