The Chan Zuckerberg Initiative Foundation concentrates its giving on building large-scale scientific and research infrastructure (especially in genomics, imaging, and AI for biology) while also funding local Bay Area education and community organizations and a smaller set of climate and public-health efforts. Grants are frequently multi-million-dollar, core-support awards to universities, CZ-created research entities, and collaborative data initiatives, with targeted investments in early childhood/primary education in East Palo Alto and community-focused work in Hawaii.
The Chan Zuckerberg Initiative Foundation’s largest recent awards show a clear pattern: it uses very large grants to build research infrastructure, especially around biology, imaging, and data-sharing systems. In 2023, it gave $100 million to President and Fellows of Harvard College for the Kempner Institute for the Study of Natural and Artificial Intelligence, alongside $85 million to Chan Zuckerberg Biohub Inc for medical research. Those grants sit next to a broader set of commitments to CZ-created research entities, university partners, and collaborative scientific platforms. The foundation also backs public-facing work outside the lab, including early education in East Palo Alto, hospital capital support in San Francisco, and ocean and climate work in Hawaii. A recurring theme is core support rather than narrow project funding, with awards often structured to sustain institutions and networks over time. Its grantmaking connects biomedical science, open data, and selected local community initiatives, with some of the biggest checks going to research hubs and partner institutions that can absorb long-term infrastructure funding.
In biology and biomedical research, the foundation gave $12,236,199 to Chan Zuckerberg Institute for Advanced Biological Imaging LLC for CZ Imaging Institute core support and $5,000,000 to University of Washington for science: cell science. It also backed open scientific infrastructure with $2,900,000 to Cold Spring Harbor Laboratory to improve the sustainability and capacity of bioRxiv/medRxiv. In climate-related research, it awarded $8,000,000 to Regents of the University of California at Berkeley for innovative genomics institute research to enhance the natural ability of plants and soil microbes to capture and store carbon, and $7,000,000 to Regents of the University of California Los Angeles for the Institute for Carbon Management for SeaChange. For education, the foundation supported The Primary School and New Schools Fund, reflecting a mix of direct school support and education infrastructure. It also funded Resolve to Save Lives Inc for general operating support.
Typical awards are large: the 25th percentile is $575,000, the median is $1,000,000, and the 75th percentile is $1,585,208. The distribution shows a foundation that often gives at institutional scale, with several grants in the multi-million-dollar range. The recent record also shows repeat support to the same organizations across years, including Chan Zuckerberg Biohub Inc, Resolve to Save Lives Inc, University of Hawaii Foundation, and The Primary School. It is a regular funder, not a DAF, and it makes program-related investments. Several active programs accept unsolicited applications, including Learning Commons, Rare As One Project, Expanding Global Access to Bioimaging, Essential Open Source Software for Science, Learning by Scientific Design Network, and Human Cell Atlas — Pilot Project Grants.
$166.1M
$7.5B
$1.5B
$323M
Most grants fall between $575K and $1.6M, with a median of $1M.
25th Percentile
$575K
Median
$1M
75th Percentile
$1.6M
About 33% of grants go to recipients in CA.
Top 5 recipient countries by grant volume for Chan Zuckerberg Initiative Foundation.
| Rank | Country | Grants | Total | Share |
|---|---|---|---|---|
| 1 | United StatesDomestic | 171 | $635.4M | 95.5% |
| 2 | United Kingdom |
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Concentrated, large-dollar grants and repeat funding: the foundation makes a small number of very large, often multi-year core support awards to universities and CZ-affiliated research entities, supplemented by targeted multi-year commitments to community education and climate/public-health pilots. Many grantees receive repeated grants, indicating preferred strategic partners.
Notable grantees: PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Kempner Institute), CHAN ZUCKERBERG BIOHUB / CZ BIOHUB entities, University of Hawaii Foundation, THE PRIMARY SCHOOL–EAST PALO ALTO, Human Cell Atlas, Inc.
Grantmaking is national, but California receives the most awards, with 33% of grants going to recipients in the HQ state. Recent California recipients include San Francisco, East Palo Alto, Berkeley, Oakland, Palo Alto, and Stanford. Outside California, notable destinations include Honolulu, Cambridge, Seattle, New York, Los Angeles, Washington, DC, Durham, and London. The country distribution is overwhelmingly U.S.-based at 95.5% of grants, with a small number in the UK and isolated grants in Switzerland and Germany.
Its recent giving centers on large-scale scientific and research infrastructure, especially genomics, advanced imaging, AI for biology, and open data systems. It also supports a smaller set of education, local community, climate, and public-health grants.
The 25th percentile is $575,000, the median is $1,000,000, and the 75th percentile is $1,585,208. Recent grants also include many awards above $5 million, showing a strong preference for institutional-scale funding.
Yes. The recent grants list includes repeat awards to Chan Zuckerberg Biohub Inc, Resolve to Save Lives Inc, University of Hawaii Foundation, and The Primary School across multiple years, indicating recurring support rather than one-off giving only.
Several active programs accept unsolicited applications, including Learning Commons, Rare As One Project, Expanding Global Access to Bioimaging, Essential Open Source Software for Science, Learning by Scientific Design Network, and Human Cell Atlas — Pilot Project Grants.
The foundation gives nationally, but California receives the most grants and 33% of grants go to recipients in the HQ state. Recent California recipients span San Francisco, East Palo Alto, Berkeley, Oakland, Palo Alto, and Stanford.
2025
Source: IRS Form 990-PF, fiscal year 2025.
| 4 |
| $6.4M |
2.2% |
| 3 | South Africa | 2 | $1.8M | 1.1% |
| 4 | Switzerland | 1 | $1.4M | 0.6% |
| 5 | Germany | 1 | $1M | 0.6% |
Recipient country reflects the grantee's headquarters per IRS 990-PF and Schedule F filings, not the program's implementation country.
Current and upcoming funding from Chan Zuckerberg Initiative Foundation that your nonprofit may be able to apply for.
Who can apply: Organizations and programs working in support of CZI's education mission. Specific eligibility criteria were not visible in the provided content.
Deadline: No deadlines were visible in the provided content.
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Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| CZ BIOHUB SF LLC | SAN FRANCISCO, CA | $60,000,000 | 2025 | SCIENCE: CZ BIOHUB SAN FRANCSICO CORE SUPPORT |
| PRESIDENT AND FELLOWS OF HARVARD COLLEGE | CAMBRIDGE, MA | $29,600,000 | 2025 | THE KEMPNER INSTITUTE FOR THE STUDY OF NATURAL AND ARTIFICIAL INTELLIGENCE AT HARVARD UNIVERSITY |
| CZ BIOHUB CHICAGO LLC | SAN FRANCISCO, CA | $18,000,000 | 2025 | SCIENCE: CZ BIOHUB CHICAGO CORE SUPPORT |
| CHAN ZUCKERBERG BIOHUB INC | SAN FRANCISCO, CA | $14,100,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| CHAN ZUCKERBERG INSTITUTE FOR ADVANCED BIOLOGICAL IMAGING LLC | SAN FRANCISCO, CA | $12,236,199 | 2025 | SCIENCE: CZ IMAGING INSTITUTE CORE SUPPORT |
| CZ BIOHUB NEW YORK LLC | SAN FRANCISCO, CA | $12,000,000 | 2025 | SCIENCE: CZ BIOHUB NEW YORK CORE SUPPORT |
| SAN FRANCISCO GENERAL HOSPITAL FOUNDATION | SAN FRANCISCO, CA | $11,500,000 | 2025 | TO SUPPORT THE CAPITAL CAMPAIGN |
| CHAN ZUCKERBERG BIOHUB INC | SAN FRANCISCO, CA | $11,500,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| UNIVERSITY OF HAWAII FOUNDATION | HONOLULU, HI | $7,700,000 | 2025 | OCEAN CONSERVATION |
| UNIVERSITY OF WASHINGTON | SEATTLE, WA | $5,000,000 | 2025 | SCIENCE: CELL SCIENCE |
| RESOLVE TO SAVE LIVES INC | NEW YORK, NY | $5,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| THE JUST TRUST FOR EDUCATION | DURHAM, NC | $4,347,043 | 2025 | FOR GENERAL OPERATING SUPPORT |
| THE UNIVERSITY COLLEGE LONDON | LONDON | $2,600,000 | 2025 | SCIENCE: IMAGING |
| UNIVERSITY OF WASHINGTON | SEATTLE, WA | $2,500,000 | 2025 | SCIENCE: SCIENCE IN SOCIETY |
| UNITED KINGDOM RESEARCH AND INNOVATION | SWINDON | $2,469,958 | 2025 | SCIENCE: IMAGING |
| THE MOREHOUSE SCHOOL OF MEDICINE INC | ATLANTA, GA | $2,300,000 | 2025 | SCIENCE: PRECISION HEALTH |
| HOWARD UNIVERSITY | WASHINGTON, DC | $2,300,000 | 2025 | SCIENCE: PRECISION HEALTH |
| MEHARRY MEDICAL COLLEGE | NASHVILLE, TN | $2,300,000 | 2025 | SCIENCE: PRECISION HEALTH |
| CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE | LOS ANGELES, CA | $2,300,000 | 2025 | SCIENCE: PRECISION HEALTH |
| YALE UNIVERSITY | NEW HAVEN, CT | $2,199,211 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| UNIVERSITY OF HAWAII FOUNDATION | HONOLULU, HI | $1,980,437 | 2025 | SCHOOL OF MEDICINE - MEDICAL TRAINING |
| HUMAN CELL ATLAS INC | CAMBRIDGE, MA | $1,700,000 | 2025 | SCIENCE: CELL SCIENCE |
| THE PEW CHARITABLE TRUSTS | WASHINGTON, DC | $1,500,000 | 2025 | SCIENCE: OPEN SCIENCE |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY | BERKELEY, CA | $1,499,993 | 2025 | SCIENCE: IMAGING |
| FEDERAL INSTITUTE OF TECHNOLOGY ZURICH | ZURICH | $1,360,000 | 2025 | SCIENCE: CELL SCIENCE |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO | SAN FRANCISCO, CA | $1,200,000 | 2025 | SCIENCE: INFECTIOUS DISEASE |
| EQUAL OPPORTUNITY SCHOOLS | SEATTLE, WA | $1,200,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| EDUCATION LEADERS OF COLOR INC | LOS ANGELES, CA | $1,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| LATINOS FOR EDUCATION INC | BELMONT, MA | $1,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| NATIONAL BOARD FOR PROFESSIONAL TEACHING STANDARDS INC | ARLINGTON, VA | $1,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA SANTA BARBARA | SANTA BARBARA, CA | $1,000,000 | 2025 | SCIENCE: IMAGING |
| SURGE INSTITUTE | CHICAGO, IL | $1,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| FPF EDUCATION AND INNOVATION FOUNDATION | WASHINGTON, DC | $1,000,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY | BERKELEY, CA | $768,646 | 2025 | SCIENCE: IMAGING |
| SEARCH INSTITUTE | MINNEAPOLIS, MN | $750,000 | 2025 | EDUCATION: ALONG |
| BUILDCASA INC | SAN FRANCISCO, CA | $725,000 | 2025 | HOUSING: INVEST IN INNOVATION |
| GRIPTAPE INC | NEW YORK, NY | $700,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| CHILD TRENDS | ROCKVILLE, MD | $560,500 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| PROJECT EVIDENT INC | BOSTON, MA | $560,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| NACA INSPIRED SCHOOLS NETWORK | ALBUQUERQUE, NM | $500,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| NATIONAL CENTER FOR CIVIC INNOVATION INC | NEW YORK, NY | $500,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| FELLOWSHIP FOR RACE & EQUITY IN EDUCATION | WASHINGTON, DC | $500,000 | 2025 | FOR GENERAL OPERATING SUPPORT |
| UNIVERSITY OF SOUTHERN CALIFORNIA | LOS ANGELES, CA | $500,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| THEIAGEN GLOBAL HEALTH INITIATIVE INC | HIGHLANDS RANCH, CO | $450,000 | 2025 | SCIENCE: INFECTIOUS DISEASE |
| INSTRUCTION PARTNERS | NASHVILLE, TN | $365,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - PRACTICE |
| INDEPENDENT SCHOOL DISTRICT NO 535 | ROCHESTER, MN | $363,160 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| TEACH PLUS INCORPORATED | BOSTON, MA | $357,227 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| FRAMEWORKS INSTITUTE | WASHINGTON, DC | $341,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| CAJON VALLEY UNION SCHOOL DISTRICT | EL CAJON, CA | $300,000 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
| REGENTS OF THE UNIVERSITY OF MICHIGAN | ANN ARBOR, MI | $253,134 | 2025 | EDUCATION: RESEARCH TO PRACTICE - MEASURES |
CZ BIOHUB SF LLC
$60,000,000SCIENCE: CZ BIOHUB SAN FRANCSICO CORE SUPPORT
PRESIDENT AND FELLOWS OF HARVARD COLLEGE
$29,600,000THE KEMPNER INSTITUTE FOR THE STUDY OF NATURAL AND ARTIFICIAL INTELLIGENCE AT HARVARD UNIVERSITY
CZ BIOHUB CHICAGO LLC
$18,000,000SCIENCE: CZ BIOHUB CHICAGO CORE SUPPORT
CHAN ZUCKERBERG BIOHUB INC
$14,100,000FOR GENERAL OPERATING SUPPORT
CHAN ZUCKERBERG INSTITUTE FOR ADVANCED BIOLOGICAL IMAGING LLC
$12,236,199SCIENCE: CZ IMAGING INSTITUTE CORE SUPPORT
CZ BIOHUB NEW YORK LLC
$12,000,000SCIENCE: CZ BIOHUB NEW YORK CORE SUPPORT
SAN FRANCISCO GENERAL HOSPITAL FOUNDATION
$11,500,000TO SUPPORT THE CAPITAL CAMPAIGN
CHAN ZUCKERBERG BIOHUB INC
$11,500,000FOR GENERAL OPERATING SUPPORT
UNIVERSITY OF HAWAII FOUNDATION
$7,700,000OCEAN CONSERVATION
UNIVERSITY OF WASHINGTON
$5,000,000SCIENCE: CELL SCIENCE
RESOLVE TO SAVE LIVES INC
$5,000,000FOR GENERAL OPERATING SUPPORT
THE JUST TRUST FOR EDUCATION
$4,347,043FOR GENERAL OPERATING SUPPORT
THE UNIVERSITY COLLEGE LONDON
$2,600,000SCIENCE: IMAGING
UNIVERSITY OF WASHINGTON
$2,500,000SCIENCE: SCIENCE IN SOCIETY
UNITED KINGDOM RESEARCH AND INNOVATION
$2,469,958SCIENCE: IMAGING
THE MOREHOUSE SCHOOL OF MEDICINE INC
$2,300,000SCIENCE: PRECISION HEALTH
HOWARD UNIVERSITY
$2,300,000SCIENCE: PRECISION HEALTH
MEHARRY MEDICAL COLLEGE
$2,300,000SCIENCE: PRECISION HEALTH
CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE
$2,300,000SCIENCE: PRECISION HEALTH
YALE UNIVERSITY
$2,199,211EDUCATION: RESEARCH TO PRACTICE - MEASURES
UNIVERSITY OF HAWAII FOUNDATION
$1,980,437SCHOOL OF MEDICINE - MEDICAL TRAINING
HUMAN CELL ATLAS INC
$1,700,000SCIENCE: CELL SCIENCE
THE PEW CHARITABLE TRUSTS
$1,500,000SCIENCE: OPEN SCIENCE
REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY
$1,499,993SCIENCE: IMAGING
FEDERAL INSTITUTE OF TECHNOLOGY ZURICH
$1,360,000SCIENCE: CELL SCIENCE
REGENTS OF THE UNIVERSITY OF CALIFORNIA SAN FRANCISCO
$1,200,000SCIENCE: INFECTIOUS DISEASE
EQUAL OPPORTUNITY SCHOOLS
$1,200,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
EDUCATION LEADERS OF COLOR INC
$1,000,000FOR GENERAL OPERATING SUPPORT
LATINOS FOR EDUCATION INC
$1,000,000FOR GENERAL OPERATING SUPPORT
NATIONAL BOARD FOR PROFESSIONAL TEACHING STANDARDS INC
$1,000,000FOR GENERAL OPERATING SUPPORT
REGENTS OF THE UNIVERSITY OF CALIFORNIA SANTA BARBARA
$1,000,000SCIENCE: IMAGING
SURGE INSTITUTE
$1,000,000FOR GENERAL OPERATING SUPPORT
FPF EDUCATION AND INNOVATION FOUNDATION
$1,000,000FOR GENERAL OPERATING SUPPORT
REGENTS OF THE UNIVERSITY OF CALIFORNIA AT BERKELEY
$768,646SCIENCE: IMAGING
SEARCH INSTITUTE
$750,000EDUCATION: ALONG
BUILDCASA INC
$725,000HOUSING: INVEST IN INNOVATION
GRIPTAPE INC
$700,000FOR GENERAL OPERATING SUPPORT
CHILD TRENDS
$560,500EDUCATION: RESEARCH TO PRACTICE - MEASURES
PROJECT EVIDENT INC
$560,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
NACA INSPIRED SCHOOLS NETWORK
$500,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
NATIONAL CENTER FOR CIVIC INNOVATION INC
$500,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
FELLOWSHIP FOR RACE & EQUITY IN EDUCATION
$500,000FOR GENERAL OPERATING SUPPORT
UNIVERSITY OF SOUTHERN CALIFORNIA
$500,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
THEIAGEN GLOBAL HEALTH INITIATIVE INC
$450,000SCIENCE: INFECTIOUS DISEASE
INSTRUCTION PARTNERS
$365,000EDUCATION: RESEARCH TO PRACTICE - PRACTICE
INDEPENDENT SCHOOL DISTRICT NO 535
$363,160EDUCATION: RESEARCH TO PRACTICE - MEASURES
TEACH PLUS INCORPORATED
$357,227EDUCATION: RESEARCH TO PRACTICE - MEASURES
FRAMEWORKS INSTITUTE
$341,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
CAJON VALLEY UNION SCHOOL DISTRICT
$300,000EDUCATION: RESEARCH TO PRACTICE - MEASURES
REGENTS OF THE UNIVERSITY OF MICHIGAN
$253,134EDUCATION: RESEARCH TO PRACTICE - MEASURES