An impact-driven public charity focused on building a sustainable funding source for innovative research, best-in-class medical education, and the highest standard of care.
Southwestern Medical Foundation’s largest recent grants center on UT Southwestern, where it has backed research, endowed chairs, professorships, and major institute-level initiatives. One 2024 grant of $34,055,660 supported research, centers, endowed chairs, professorships, and other programs at UT Southwestern, while a 2023 grant of $31,566,075 supported the B. R. Bowling Fund O’Donnell Brain Institute. That pattern shows a funder built around long-term institutional support rather than one-off project funding. The foundation’s giving also includes large annual distributions tied to endowment and operating support, such as semi-annual 4.5% distributions in 2025 and annual distributions from the Mary R. Saner Endowment Fund. Across the recent grants list, UT Southwestern receives repeated support for brain and neurological disorders, cancer research, medical education, and patient-related needs. Grants also appear for clinical infrastructure, such as the TI Biomedical Engineering and Sciences Building and an operating room “black box.” The portfolio points to a medical-centered funder that uses sizable, recurring grants to strengthen research capacity, academic medicine, and specialized care at a single institution.
Brain and neurological research is a major theme. Southwestern Medical Foundation gave $1,380,000 in 2025 to support initiatives of the Peter O’Donnell, Jr. Brain Institute, and $960,000 in 2024 to support the Neuro Wellness in Brains of Infants (NEWBI) program. Earlier grants also supported cerebellum disorders research and neuroscience research at the Harold and Annette Simmons Comprehensive Center for Research and Treatment in Brain and Neurological Disorders. Cancer-related support is another clear area. In 2025, the foundation awarded $1,595,000 to Cancer Prevention Initiative Inc for the Cancer Prevention Initiative, $1,000,040 to UT Southwestern for the Harold C. Simmons Comprehensive Cancer Center, and $500,000 for prostate cancer research under Dr. Kevin Courtney. Medical education and training also appear in the recent record, including $2,127,101 in 2025 for key activities at UT Southwestern Medical School and $1,000,000 in 2024 for the TI Biomedical Engineering and Sciences Building.
Typical grants are substantial: the 25th percentile is $19,392, the median is $50,000, and the 75th percentile is $165,625. The recent record also shows repeated large distributions in the millions, alongside smaller endowment distributions and program awards. UT Southwestern appears across multiple years and at multiple funding levels, indicating recurring support rather than isolated gifts. The foundation is a public charity with annual grants of $164,881,615 and does not fund individuals or make program-related investments.
$164.9M
$1.3B
$183.1M
$55.3M
Most grants fall between $19K and $166K, with a median of $50K.
25th Percentile
$19K
Median
$50K
75th Percentile
$166K
About 97% of grants go to recipients in TX.
MICHAEL MCMAHAN
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Giving is overwhelmingly concentrated in Texas: 97% of grants go to recipients in the HQ state, and the top state by grant count is TX. Recent grants in the list are centered in Dallas, including UT Southwestern and Cancer Prevention Initiative Inc. The recipient-country distribution is entirely U.S.-based, with 189 grants in the US and no non-U.S. recipient countries in the recent data.
The recent grants point to medical research, medical education, patient care, pediatrics, brain research and neurology, cancer research, public health, mental health, and addiction psychiatry. Named programs include the O’Donnell Brain Institute, the Harold C. Simmons Comprehensive Cancer Center, and the NEWBI program.
UT Southwestern is the dominant recipient in the recent grants list, appearing repeatedly across 2023, 2024, and 2025. The foundation also supports Dallas-based organizations such as Cancer Prevention Initiative Inc.
The typical grant size is $50,000 at the median, with a 25th percentile of $19,392 and a 75th percentile of $165,625. The recent list also includes very large institutional grants in the millions, especially to UT Southwestern.
The recent recipient-country distribution is entirely U.S.-based: 189 grants went to US recipients, or 100.0% of the listed grants.
2025
Source: IRS Form 990-PF, fiscal year 2025.
Most recent grants reported to the IRS.
| Recipient | Location | Amount | Year | Purpose |
|---|---|---|---|---|
| UT SOUTHWESTERN | DALLAS, TX | $17,475,561 | 2025 | SUMMER 2024 SEMI-ANNUAL 4.5% DISTRIBUTIONS |
| UT SOUTHWESTERN | DALLAS, TX | $17,345,872 | 2025 | SPRING 2024 SEMI-ANNUAL 4.5% DISTRIBUTIONS |
| UT SOUTHWESTERN | DALLAS, TX | $2,127,101 | 2025 | TO SUPPORT KEY ACTIVITIES AT UT SOUTHWESTERN MEDICAL SCHOOL |
| CANCER PREVENTION INITIATIVE INC | DALLAS, TX | $1,595,000 | 2025 | CANCER PREVENTION INITIATIVE |
| UT SOUTHWESTERN | DALLAS, TX | $1,380,000 | 2025 | TO SUPPORT INITIATIVES OF THE PETER O'DONNELL, JR. BRAIN INSTITUTE |
| UT SOUTHWESTERN | DALLAS, TX | $1,000,040 | 2025 | TO SUPPORT THE HAROLD C. SIMMONS COMPREHENSIVE CANCER CENTER |
| UT SOUTHWESTERN | DALLAS, TX | $677,048 | 2025 | MARY R. SANER ENDOWMENT FUND ANNUAL 4% DISTRIBUTION TO BE APPLIED TO OUTSTANDING HOSPITAL BILLS FOR INDIGENT ELDERLY PATIENTS |
| UT SOUTHWESTERN | DALLAS, TX | $572,440 | 2025 | TO SUPPORT THE O'DONNELL BRAIN INSTITUTE |
| UT SOUTHWESTERN | DALLAS, TX | $537,996 | 2025 | TO SUPPORT VARIOUS INITIATIVES AT UTSW |
| UT SOUTHWESTERN | DALLAS, TX | $500,000 | 2025 | TO SUPPORT GULF WAR SYNDROME RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $500,000 | 2025 | TO SUPPORT THE EXPANSION OF AN OPERATING ROOM "BLACK BOX" |
| UT SOUTHWESTERN | DALLAS, TX | $500,000 | 2025 | TO SUPPORT RESEARCH IN THE AREA OF PROSTATE CANCER UNDER THE DIRECTION OF DR. KEVIN COURTNEY AND IN COLLABORATION WITH THE GENITOURINARY DISEASE ORIENTED TEAM OF THE UT SOUTHWESTERN HAROLD C. SIMMONS COMPREHENSIVE CANCER CENTER FOR THE PURPOSE OF COORDINATING CLINICAL TRIALS TO ADVANCE RE OF PATIENTS WITH PROSTATE CANCER |
| UT SOUTHWESTERN | DALLAS, TX | $300,000 | 2025 | TO SUPPORT UT SOUTHWESTERN CLINICAL SERVICE INITIATIVE (EXCELLENCE IN CLINICAL PRACTICE) |
| PARKLAND FOUNDATION | DALLAS, TX | $252,500 | 2025 | COMMUNITY EVENT |
| UT SOUTHWESTERN | DALLAS, TX | $250,000 | 2025 | TO SUPPORT NEW EQUIPMENT FOR ALZHEIMER'S RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $160,000 | 2025 | TO SUPPORT THE HEALING OVER PSYCHOSIS EARLY PROGRAM UNDER THE DIRECTION OF ELENA I. IVLEVA, M.D., PH.D. |
| UT SOUTHWESTERN | DALLAS, TX | $150,000 | 2025 | TO SUPPORT THE LAUNCH OF A NEW CHAPLAINCY AND BEREAVEMENT SUPPORT PROGRAM IN THE SIMMONS CANCER CENTER AT UTSW |
| UT SOUTHWESTERN | DALLAS, TX | $150,000 | 2025 | TO SUPPORT 2024 CARY COUNCIL DOCSTARS |
| UT SOUTHWESTERN | DALLAS, TX | $125,000 | 2025 | TO SUPPORT THE AMGEN SCHOLARS PROGRAM UNDER THE DIRECTION OF ARNALDO DIAZ VAZQUEZ, PH.D. |
| UT SOUTHWESTERN | DALLAS, TX | $111,105 | 2025 | TO SUPPORT THE CENTER FOR DEPRESSION RESEARCH AND CLINICAL CARE |
| UT SOUTHWESTERN | DALLAS, TX | $104,553 | 2025 | TO SUPPORT ALZHEIMER'S RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $100,000 | 2025 | TO SUPPORT POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $100,000 | 2025 | TO SUPPORT BEHAVIORAL NEUROLOGY AND DEMENTIA RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $100,000 | 2025 | TO SUPPORT THE CHAIR AND EFFORTS IN OBESITY AND DIABETES RESEARCH OF DR. SHAWN BURGESS |
| UT SOUTHWESTERN | DALLAS, TX | $100,000 | 2025 | TO SUPPORT ONCOLOGY SERVICES |
| COLLIN COUNTY HEALTH CARE FOUNDATION | MCKINNEY, TX | $98,000 | 2025 | TO SUPPORT THE PROGRAMS OF THE COLLIN COUNTY HEALTH DEPARTMENT |
| DALLAS COUNTY MEDICAL SOCIETY | DALLAS, TX | $80,000 | 2025 | TO SUPPORT THE DALLAS COUNTY MEDICAL SOCIETY |
| AMERICAN ACADEMY OF RESTORATIVE DENTISTRY | BROKEN ARROW, OK | $73,200 | 2025 | TO SUPPORT THE EDUCATIONAL EFFORTS OF THE AMERICAN ACADEMY OF RESTORATIVE DENTISTRY |
| UT SOUTHWESTERN | DALLAS, TX | $60,000 | 2025 | TO SUPPORT PROJECT "INVESTIGATING HUMAN TUMOR METABOLISM IN VIVO TO PREDICT MELANOMA METASTASIS AND THERAPY RESPONSE" |
| PHOENIX HOUSES OF TEXAS INC | DALLAS, TX | $53,528 | 2025 | TO SUPPORT PROGRAMS AT THE PHOENIX HOUSE OF TEXAS |
| UT SOUTHWESTERN | DALLAS, TX | $53,104 | 2025 | TO SUPPORT THE ELLER CDRC RESEARCH FUND |
| UT SOUTHWESTERN | DALLAS, TX | $50,000 | 2025 | TO SUPPORT THE LUNG TRANSPLANT PROGRAM |
| UT SOUTHWESTERN | DALLAS, TX | $50,000 | 2025 | TO SUPPORT GASTROINTESTINAL CANCER RESEARCH UNDER THE DIRECTION OF TIMOTHY BROWN, M.D. |
| UT SOUTHWESTERN | DALLAS, TX | $50,000 | 2025 | TO SUPPORT THE HOPE PROGRAM |
| UT SOUTHWESTERN | DALLAS, TX | $50,000 | 2025 | TO SUPPORT THE CDRC BIOREPOSITORY |
| UT SOUTHWESTERN | DALLAS, TX | $49,935 | 2025 | TO SUPPORT MEDICAL RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $45,000 | 2025 | TO SUPPORT BREAST CANCER RESEARCH |
| TEXAS WOMAN'S UNIVERSITY | DALLAS, TX | $40,000 | 2025 | TO SUPPORT THE STROKE CENTER AT TEXAS WOMAN'S UNIVERSITY DALLAS |
| UT SOUTHWESTERN | DALLAS, TX | $30,000 | 2025 | TO SUPPORT DR. PANAGIOTIS MASTORAKOS, ASSISTANT PROFESSOR OF NUEROLOGICAL SURGERY. |
| UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | GREENSBORO, NC | $27,544 | 2025 | TO SUPPORT THE BRENDA WELLING RECHTINE SCHOLARSHIP FUND |
| UT SOUTHWESTERN | DALLAS, TX | $27,500 | 2025 | TO SUPPORT DEPRESSION RESEARCH AND CLINICAL CARE |
| UT SOUTHWESTERN | DALLAS, TX | $25,000 | 2025 | TO SUPPORT MISCELLANOUS INITIATIVES AT UT SOUTHWESTERN |
| UT SOUTHWESTERN | DALLAS, TX | $20,000 | 2025 | TO SUPPORT FUND FOR GI MOTILITY AT UTSW |
| YOUNGSTOWN STATE UNIVERSITY FOUNDATION | YOUNGSTOWN, OH | $18,364 | 2025 | TO SUPPORT THE THOMAS W. CROGAN III MEMORIAL SCHOLARSHIP IN NURSING FUND |
| UT SOUTHWESTERN | DALLAS, TX | $18,200 | 2025 | TO SUPPORT WOMEN IN SCIENCE AND MEDICINE ADVISORY COMMITTEE |
| UT SOUTHWESTERN | DALLAS, TX | $18,000 | 2025 | TO SUPPORT BRAIN TUMOR RESEARCH UNDER ELIZABETH MAHER, M.D., PH.D. |
| UT SOUTHWESTERN | DALLAS, TX | $17,795 | 2025 | TO SUPPORT THE CONSTRUCTION OF A NEW PEDIATRIC CAMPUS JOINTLY DEVELOPED BY UTSW AND CHILDREN'S |
| UT SOUTHWESTERN | DALLAS, TX | $15,000 | 2025 | TO SUPPORT THE RESEARCH UNDER THE DIRECTION OF DR. DAVID GERBER |
| UT SOUTHWESTERN | DALLAS, TX | $15,000 | 2025 | TO SUPPORT OVARIAN CANCER RESEARCH |
| UT SOUTHWESTERN | DALLAS, TX | $11,600 | 2025 | TO SUPPORT THE PARKLAND MEMORIAL HOSPITAL NEURO-TRAUMA AWARD HONORING MAUREEN AND ROBERT DECHERD, DUKE SAMSON, M.D., JIM THORNTON, M.D. AND BABU WELCH, M.D. ENDOWMENT |
UT SOUTHWESTERN
$17,475,561SUMMER 2024 SEMI-ANNUAL 4.5% DISTRIBUTIONS
UT SOUTHWESTERN
$17,345,872SPRING 2024 SEMI-ANNUAL 4.5% DISTRIBUTIONS
UT SOUTHWESTERN
$2,127,101TO SUPPORT KEY ACTIVITIES AT UT SOUTHWESTERN MEDICAL SCHOOL
CANCER PREVENTION INITIATIVE INC
$1,595,000CANCER PREVENTION INITIATIVE
UT SOUTHWESTERN
$1,380,000TO SUPPORT INITIATIVES OF THE PETER O'DONNELL, JR. BRAIN INSTITUTE
UT SOUTHWESTERN
$1,000,040TO SUPPORT THE HAROLD C. SIMMONS COMPREHENSIVE CANCER CENTER
UT SOUTHWESTERN
$677,048MARY R. SANER ENDOWMENT FUND ANNUAL 4% DISTRIBUTION TO BE APPLIED TO OUTSTANDING HOSPITAL BILLS FOR INDIGENT ELDERLY PATIENTS
UT SOUTHWESTERN
$572,440TO SUPPORT THE O'DONNELL BRAIN INSTITUTE
UT SOUTHWESTERN
$537,996TO SUPPORT VARIOUS INITIATIVES AT UTSW
UT SOUTHWESTERN
$500,000TO SUPPORT GULF WAR SYNDROME RESEARCH
UT SOUTHWESTERN
$500,000TO SUPPORT THE EXPANSION OF AN OPERATING ROOM "BLACK BOX"
UT SOUTHWESTERN
$500,000TO SUPPORT RESEARCH IN THE AREA OF PROSTATE CANCER UNDER THE DIRECTION OF DR. KEVIN COURTNEY AND IN COLLABORATION WITH THE GENITOURINARY DISEASE ORIENTED TEAM OF THE UT SOUTHWESTERN HAROLD C. SIMMONS COMPREHENSIVE CANCER CENTER FOR THE PURPOSE OF COORDINATING CLINICAL TRIALS TO ADVANCE RE OF PATIENTS WITH PROSTATE CANCER
UT SOUTHWESTERN
$300,000TO SUPPORT UT SOUTHWESTERN CLINICAL SERVICE INITIATIVE (EXCELLENCE IN CLINICAL PRACTICE)
PARKLAND FOUNDATION
$252,500COMMUNITY EVENT
UT SOUTHWESTERN
$250,000TO SUPPORT NEW EQUIPMENT FOR ALZHEIMER'S RESEARCH
UT SOUTHWESTERN
$160,000TO SUPPORT THE HEALING OVER PSYCHOSIS EARLY PROGRAM UNDER THE DIRECTION OF ELENA I. IVLEVA, M.D., PH.D.
UT SOUTHWESTERN
$150,000TO SUPPORT THE LAUNCH OF A NEW CHAPLAINCY AND BEREAVEMENT SUPPORT PROGRAM IN THE SIMMONS CANCER CENTER AT UTSW
UT SOUTHWESTERN
$150,000TO SUPPORT 2024 CARY COUNCIL DOCSTARS
UT SOUTHWESTERN
$125,000TO SUPPORT THE AMGEN SCHOLARS PROGRAM UNDER THE DIRECTION OF ARNALDO DIAZ VAZQUEZ, PH.D.
UT SOUTHWESTERN
$111,105TO SUPPORT THE CENTER FOR DEPRESSION RESEARCH AND CLINICAL CARE
UT SOUTHWESTERN
$104,553TO SUPPORT ALZHEIMER'S RESEARCH
UT SOUTHWESTERN
$100,000TO SUPPORT POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) RESEARCH
UT SOUTHWESTERN
$100,000TO SUPPORT BEHAVIORAL NEUROLOGY AND DEMENTIA RESEARCH
UT SOUTHWESTERN
$100,000TO SUPPORT THE CHAIR AND EFFORTS IN OBESITY AND DIABETES RESEARCH OF DR. SHAWN BURGESS
UT SOUTHWESTERN
$100,000TO SUPPORT ONCOLOGY SERVICES
COLLIN COUNTY HEALTH CARE FOUNDATION
$98,000TO SUPPORT THE PROGRAMS OF THE COLLIN COUNTY HEALTH DEPARTMENT
DALLAS COUNTY MEDICAL SOCIETY
$80,000TO SUPPORT THE DALLAS COUNTY MEDICAL SOCIETY
AMERICAN ACADEMY OF RESTORATIVE DENTISTRY
$73,200TO SUPPORT THE EDUCATIONAL EFFORTS OF THE AMERICAN ACADEMY OF RESTORATIVE DENTISTRY
UT SOUTHWESTERN
$60,000TO SUPPORT PROJECT "INVESTIGATING HUMAN TUMOR METABOLISM IN VIVO TO PREDICT MELANOMA METASTASIS AND THERAPY RESPONSE"
PHOENIX HOUSES OF TEXAS INC
$53,528TO SUPPORT PROGRAMS AT THE PHOENIX HOUSE OF TEXAS
UT SOUTHWESTERN
$53,104TO SUPPORT THE ELLER CDRC RESEARCH FUND
UT SOUTHWESTERN
$50,000TO SUPPORT THE LUNG TRANSPLANT PROGRAM
UT SOUTHWESTERN
$50,000TO SUPPORT GASTROINTESTINAL CANCER RESEARCH UNDER THE DIRECTION OF TIMOTHY BROWN, M.D.
UT SOUTHWESTERN
$50,000TO SUPPORT THE HOPE PROGRAM
UT SOUTHWESTERN
$50,000TO SUPPORT THE CDRC BIOREPOSITORY
UT SOUTHWESTERN
$49,935TO SUPPORT MEDICAL RESEARCH
UT SOUTHWESTERN
$45,000TO SUPPORT BREAST CANCER RESEARCH
TEXAS WOMAN'S UNIVERSITY
$40,000TO SUPPORT THE STROKE CENTER AT TEXAS WOMAN'S UNIVERSITY DALLAS
UT SOUTHWESTERN
$30,000TO SUPPORT DR. PANAGIOTIS MASTORAKOS, ASSISTANT PROFESSOR OF NUEROLOGICAL SURGERY.
UNIVERSITY OF NORTH CAROLINA AT GREENSBORO
$27,544TO SUPPORT THE BRENDA WELLING RECHTINE SCHOLARSHIP FUND
UT SOUTHWESTERN
$27,500TO SUPPORT DEPRESSION RESEARCH AND CLINICAL CARE
UT SOUTHWESTERN
$25,000TO SUPPORT MISCELLANOUS INITIATIVES AT UT SOUTHWESTERN
UT SOUTHWESTERN
$20,000TO SUPPORT FUND FOR GI MOTILITY AT UTSW
YOUNGSTOWN STATE UNIVERSITY FOUNDATION
$18,364TO SUPPORT THE THOMAS W. CROGAN III MEMORIAL SCHOLARSHIP IN NURSING FUND
UT SOUTHWESTERN
$18,200TO SUPPORT WOMEN IN SCIENCE AND MEDICINE ADVISORY COMMITTEE
UT SOUTHWESTERN
$18,000TO SUPPORT BRAIN TUMOR RESEARCH UNDER ELIZABETH MAHER, M.D., PH.D.
UT SOUTHWESTERN
$17,795TO SUPPORT THE CONSTRUCTION OF A NEW PEDIATRIC CAMPUS JOINTLY DEVELOPED BY UTSW AND CHILDREN'S
UT SOUTHWESTERN
$15,000TO SUPPORT THE RESEARCH UNDER THE DIRECTION OF DR. DAVID GERBER
UT SOUTHWESTERN
$15,000TO SUPPORT OVARIAN CANCER RESEARCH
UT SOUTHWESTERN
$11,600TO SUPPORT THE PARKLAND MEMORIAL HOSPITAL NEURO-TRAUMA AWARD HONORING MAUREEN AND ROBERT DECHERD, DUKE SAMSON, M.D., JIM THORNTON, M.D. AND BABU WELCH, M.D. ENDOWMENT